Thrombopoietin Induces Phosphoinositol 3-Kinase Activation through SHP2, Gab, and Insulin Receptor Substrate Proteins in BAF3 Cells and Primary Murine Megakaryocytes

Journal of Biological Chemistry

Volumn 276, Issue 4, 2001, Pages 2494-2502

  Miyakawa, Yoshitaka ^b   Rojnuckarin, Ponlapat ^b   Habib, Tania ^b   Kaushansky, Kenneth ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; COMPLEXATION; ENZYME KINETICS; PRECIPITATION (CHEMICAL); PROTEINS;

PHOSPHORYLATION;

BIOCHEMISTRY;

ADAPTOR PROTEIN; BINDING PROTEIN; GENE PRODUCT; INSULIN RECEPTOR SUBSTRATE PROTEIN; PHOSPHOINOSITOL 3 KINASE; PHOSPHOPROTEIN; PHOSPHOPROTEIN 100; PHOSPHOTRANSFERASE; PROTEIN BAF3; PROTEIN GAB; PROTEIN KINASE B; PROTEIN MPL; PROTEIN P85; PROTEIN TYROSINE PHOSPHATASE SHP 2; THROMBOPOIETIN; UNCLASSIFIED DRUG; GAB2 PROTEIN, MOUSE; INSULIN RECEPTOR SUBSTRATE 2 PROTEIN; INSULIN RECEPTOR SUBSTRATE-2 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; PTPN6 PROTEIN, MOUSE; SIGNAL PEPTIDE; SRC HOMOLOGY 2 (SH2) DOMAIN CONTAINING PHOSPHATASES; SRC HOMOLOGY-2 (SH2) DOMAIN-CONTAINING PHOSPHATASES;

ANIMAL CELL; ARTICLE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; COMPLEX FORMATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ERYTHROID PRECURSOR CELL; HORMONE ACTION; IMMUNOPRECIPITATION; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECT; HEMATOPOIESIS; METABOLISM;

ANIMALIA; MURINAE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; ENZYME ACTIVATION; HEMATOPOIESIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEGAKARYOCYTES; MICE; PHOSPHOPROTEINS; PROTEIN-TYROSINE-PHOSPHATASE; SHP1 PROTEIN TYROSINE PHOSPHATASE; THROMBOPOIETIN;

EID: 0035951790     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M002633200     Document Type: Article

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