Degradation of IRS1 leads to impaired glucose uptake in adipose tissue of the type 2 diabetes mouse model TALLYHO/Jng

Journal of Endocrinology

Volumn 203, Issue 1, 2009, Pages 65-74

  Wang, Yun ^a   Nishina, Patsy M ^a   Naggert, Jürgen K ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

20S PROTEASOME; GLUCOSE TRANSPORTER 4; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 9; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; SERINE; STRESS ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG; GLUCOSE; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, MOUSE; SLC2A4 PROTEIN, MOUSE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLUCOSE TRANSPORT; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INSULIN RESISTANCE; MALE; MICROSOME; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING; ADIPOCYTE; ANIMAL; DISEASE MODEL; METABOLISM; MOUSE STRAIN;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED STRAINS; PROTEASOME ENDOPEPTIDASE COMPLEX; SIGNAL TRANSDUCTION;

EID: 70349757694     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-09-0026     Document Type: Article

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