Adenosine A2A receptor activation reduces infarct size in the isolated, perfused mouse heart by inhibiting resident cardiac mast cell degranulation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 5, 2008, Pages

  Rork, Tyler H ^a   Wallace, Kori L ^a   Kennedy, Dylan P ^a   Marshall, Melissa A ^a   Lankford, Amy R ^b   Linden, Joel ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

ATL146e; Bone marrow chimera; CGS 21680; Langendorff; Tryptase

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 [3 [6 AMINO 9 (5 ETHYLCARBAMOYL 3,4 DIHYDROXYTETRAHYDRO 2 FURYL) 9H PURIN 2 YL] 2 PROPYNYL]CYCLOHEXANECARBOXYLIC ACID METHYL ESTER; ADENOSINE A2A RECEPTOR; TRYPTASE; ADENOSINE; CARDIOVASCULAR AGENT; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; DRUG DERIVATIVE; PHENETHYLAMINE DERIVATIVE; PURINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BONE MARROW TRANSPLANTATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DEGRANULATION; ENZYME RELEASE; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART PERFUSION; HEART PROTECTION; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BINDING; REPERFUSION INJURY; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; GENETICS; HEART INFARCTION; HEART MUSCLE; METABOLISM; MOUSE MUTANT; PATHOLOGY; PERFUSION; TIME; WHOLE BODY RADIATION;

ADENOSINE; ANIMALS; BONE MARROW TRANSPLANTATION; CARDIOVASCULAR AGENTS; CELL DEGRANULATION; CELLS, CULTURED; CYCLOHEXANECARBOXYLIC ACIDS; DISEASE MODELS, ANIMAL; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PERFUSION; PHENETHYLAMINES; PURINES; RECEPTOR, ADENOSINE A2A; TIME FACTORS; TRYPTASES; WHOLE-BODY IRRADIATION;

EID: 57049180745     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.495.2008     Document Type: Article

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