Luminal L-glutamate enhances duodenal mucosal defense mechanisms via multiple glutamate receptors in rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 297, Issue 4, 2009, Pages

  Akiba, Yasutada ^a,b,c   Watanabe, Chikako ^a,b   Mizumori, Misa ^a,b   Kaunitz, Jonathan D ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Brentwood Biomedical Research Institute Los Angeles   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Bicarbonate secretion; Intracellular alkalinization; Monosodium glutamate; Mucus secretion; Taste receptor

Indexed keywords

ASPARTIC ACID; CALCIUM SENSING RECEPTOR; CAPSAICIN; GLUTAMATE RECEPTOR; GLUTAMIC ACID; INDOMETACIN; INOSINE PHOSPHATE; LEUCINE; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 4; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; AGENTS ACTING ON THE PERIPHERAL NERVOUS AND NEUROMUSCULAR SYSTEMS; AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT; BICARBONATE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL STIMULATING AGENT; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; METABOTROPIC RECEPTOR; PROSTAGLANDIN SYNTHASE INHIBITOR;

ALKALINIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; CELL DAMAGE; CELL PH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEFENSE MECHANISM; DRUG EFFECT; DUODENUM MUCOSA; EPITHELIUM CELL; MALE; MUCUS SECRETION; NONHUMAN; NUCLEOTIDE SEQUENCE; PERFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TASTE BUD; ANIMAL; CELL PROTECTION; DOSE RESPONSE; DRUG EFFECTS; DUODENUM; INNERVATION; INTESTINE MUCOSA; LASER DOPPLER FLOWMETRY; METABOLISM; MUCUS; PH; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TASTE; TIME; VASCULARIZATION;

ANIMALS; BICARBONATES; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNEL BLOCKERS; CYCLOOXYGENASE INHIBITORS; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DUODENUM; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; INTESTINAL MUCOSA; LASER-DOPPLER FLOWMETRY; MALE; MUCUS; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCIUM-SENSING; RECEPTORS, METABOTROPIC GLUTAMATE; REGIONAL BLOOD FLOW; SENSORY SYSTEM AGENTS; SIGNAL TRANSDUCTION; TASTE; TIME FACTORS;

EID: 70349733123     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90605.2008     Document Type: Article

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