A novel small molecule CFTR inhibitor attenuates HCO3 - secretion and duodenal ulcer formation in rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 289, Issue 4 52-4, 2005, Pages

  Akiba, Yasutada ^b,c,d   Jung, Michael ^a   Ouk, Samedy ^a   Kaunitz, Jonathan D ^a,b,c,d,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Brentwood Biomedical Research Institute Los Angeles   (United States)

^e VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

CFTRinh 172; Cysteamine; Duodenal bicarbonate secretion; Duodenal ulcer; Luminal acid

Indexed keywords

BICARBONATE; MERCAPTAMINE; PENTAGASTRIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRANSMEMBRANE CONDUCTANCE REGULATOR INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG POTENCY; DUODENUM MUCOSA; DUODENUM ULCER; INTESTINE PERFUSION; MALE; NONHUMAN; PH MEASUREMENT; PREDICTION; PRIORITY JOURNAL; RAT; STOMACH ACID SECRETION;

ANIMALS; BENZOIC ACIDS; BICARBONATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTAMINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DUODENAL ULCER; DUODENUM; GASTRIC ACID; MALE; RATS; RATS, SPRAGUE-DAWLEY; SULFHYDRYL REAGENTS; THIAZOLES; THIAZOLIDINES;

EID: 25444492583     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00130.2005     Document Type: Article

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