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Volumn 10, Issue , 2009, Pages 94-

Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: The Finnish diabetes prevention study

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DNA; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LIPID; TRIACYLGLYCEROL; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; MITOCHONDRIAL UNCOUPLING PROTEIN 3;

EID: 70349563773     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-10-94     Document Type: Article
Times cited : (54)

References (58)
  • 1
    • 33751269135 scopus 로고    scopus 로고
    • Regulation of insulin secretion by uncoupling protein
    • Chan CB, Kashemsant N. Regulation of insulin secretion by uncoupling protein. Biochem Soc Trans 2006, 34(Pt 5):802-805.
    • (2006) Biochem Soc Trans , vol.34 , Issue.PT 5 , pp. 802-805
    • Chan, C.B.1    Kashemsant, N.2
  • 6
    • 0030803678 scopus 로고    scopus 로고
    • The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts
    • 10.1074/jbc.272.41.25433, 9325252
    • Solanes G, Vidal-Puig A, Grujic D, Flier JS, Lowell BB. The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts. J Biol Chem 1997, 272(41):25433-25436. 10.1074/jbc.272.41.25433, 9325252.
    • (1997) J Biol Chem , vol.272 , Issue.41 , pp. 25433-25436
    • Solanes, G.1    Vidal-Puig, A.2    Grujic, D.3    Flier, J.S.4    Lowell, B.B.5
  • 9
    • 15444342187 scopus 로고    scopus 로고
    • Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity
    • 10.1210/jc.83.8.2800, 9709950
    • Kubota T, Mori H, Tamori Y, Okazawa H, Fukuda T, Miki M, Ito C, Fleury C, Bouillaud F, Kasuga M. Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity. J Clin Endocrinol Metab 1998, 83(8):2800-2804. 10.1210/jc.83.8.2800, 9709950.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.8 , pp. 2800-2804
    • Kubota, T.1    Mori, H.2    Tamori, Y.3    Okazawa, H.4    Fukuda, T.5    Miki, M.6    Ito, C.7    Fleury, C.8    Bouillaud, F.9    Kasuga, M.10
  • 11
    • 0034766937 scopus 로고    scopus 로고
    • Genetic variation at the uncoupling protein 1, 2 and 3 loci and the response to long-term overfeeding
    • 10.1038/sj.ejcn.1601261, 11641751
    • Ukkola O, Tremblay A, Sun G, Chagnon YC, Bouchard C. Genetic variation at the uncoupling protein 1, 2 and 3 loci and the response to long-term overfeeding. Eur J Clin Nutr 2001, 55(11):1008-1015. 10.1038/sj.ejcn.1601261, 11641751.
    • (2001) Eur J Clin Nutr , vol.55 , Issue.11 , pp. 1008-1015
    • Ukkola, O.1    Tremblay, A.2    Sun, G.3    Chagnon, Y.C.4    Bouchard, C.5
  • 12
    • 0037145722 scopus 로고    scopus 로고
    • Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome
    • Rosmond R, Bouchard C, Bjorntorp P. Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome. Biochim Biophys Acta 2002, 1588(2):103-105.
    • (2002) Biochim Biophys Acta , vol.1588 , Issue.2 , pp. 103-105
    • Rosmond, R.1    Bouchard, C.2    Bjorntorp, P.3
  • 13
    • 0346787545 scopus 로고    scopus 로고
    • Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion
    • 10.1152/ajpendo.00231.2003, 12915397
    • Wang H, Chu WS, Lu T, Hasstedt SJ, Kern PA, Elbein SC. Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion. Am J Physiol Endocrinol Metab 2004, 286(1):E1-7. 10.1152/ajpendo.00231.2003, 12915397.
    • (2004) Am J Physiol Endocrinol Metab , vol.286 , Issue.1
    • Wang, H.1    Chu, W.S.2    Lu, T.3    Hasstedt, S.J.4    Kern, P.A.5    Elbein, S.C.6
  • 14
    • 0036830548 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans
    • 10.2337/diabetes.51.11.3331, 12401727
    • Krempler F, Esterbauer H, Weitgasser R, Ebenbichler C, Patsch JR, Miller K, Xie M, Linnemayr V, Oberkofler H, Patsch W. A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans. Diabetes 2002, 51(11):3331-3335. 10.2337/diabetes.51.11.3331, 12401727.
    • (2002) Diabetes , vol.51 , Issue.11 , pp. 3331-3335
    • Krempler, F.1    Esterbauer, H.2    Weitgasser, R.3    Ebenbichler, C.4    Patsch, J.R.5    Miller, K.6    Xie, M.7    Linnemayr, V.8    Oberkofler, H.9    Patsch, W.10
  • 16
    • 0347990596 scopus 로고    scopus 로고
    • The common -866 g/a polymorphism in the promoter of uncoupling protein 2 is associated with increased carbohydrate and decreased lipid oxidation in juvenile obesity
    • 10.2337/diabetes.53.1.235, 14693721
    • Le Fur S, Le Stunff C, Dos Santos C, Bougneres P. The common -866 g/a polymorphism in the promoter of uncoupling protein 2 is associated with increased carbohydrate and decreased lipid oxidation in juvenile obesity. Diabetes 2004, 53(1):235-239. 10.2337/diabetes.53.1.235, 14693721.
    • (2004) Diabetes , vol.53 , Issue.1 , pp. 235-239
    • Le Fur, S.1    Le Stunff, C.2    Dos Santos, C.3    Bougneres, P.4
  • 18
    • 1942424804 scopus 로고    scopus 로고
    • Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2
    • 10.1016/j.ehj.2004.01.007, 15039126
    • Dhamrait SS, Stephens JW, Cooper JA, Acharya J, Mani AR, Moore K, Miller GJ, Humphries SE, Hurel SJ, Montgomery HE. Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2. Eur Heart J 2004, 25(6):468-475. 10.1016/j.ehj.2004.01.007, 15039126.
    • (2004) Eur Heart J , vol.25 , Issue.6 , pp. 468-475
    • Dhamrait, S.S.1    Stephens, J.W.2    Cooper, J.A.3    Acharya, J.4    Mani, A.R.5    Moore, K.6    Miller, G.J.7    Humphries, S.E.8    Hurel, S.J.9    Montgomery, H.E.10
  • 19
    • 0034883804 scopus 로고    scopus 로고
    • Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes
    • 10.1007/s001250100596, 11484071
    • Dalgaard LT, Pedersen O. Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes. Diabetologia 2001, 44(8):946-965. 10.1007/s001250100596, 11484071.
    • (2001) Diabetologia , vol.44 , Issue.8 , pp. 946-965
    • Dalgaard, L.T.1    Pedersen, O.2
  • 20
    • 27744550916 scopus 로고    scopus 로고
    • Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians
    • 10.1007/s00125-005-1934-9, 16167150
    • Kovacs P, Ma L, Hanson RL, Franks P, Stumvoll M, Bogardus C, Baier LJ. Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians. Diabetologia 2005, 48(11):2292-2295. 10.1007/s00125-005-1934-9, 16167150.
    • (2005) Diabetologia , vol.48 , Issue.11 , pp. 2292-2295
    • Kovacs, P.1    Ma, L.2    Hanson, R.L.3    Franks, P.4    Stumvoll, M.5    Bogardus, C.6    Baier, L.J.7
  • 21
    • 14644390316 scopus 로고    scopus 로고
    • Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women
    • 10.1161/01.ATV.0000153141.42033.22, 15604415
    • Oberkofler H, Iglseder B, Klein K, Unger J, Haltmayer M, Krempler F, Paulweber B, Patsch W. Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women. Arterioscler Thromb Vasc Biol 2005, 25(3):604-610. 10.1161/01.ATV.0000153141.42033.22, 15604415.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.3 , pp. 604-610
    • Oberkofler, H.1    Iglseder, B.2    Klein, K.3    Unger, J.4    Haltmayer, M.5    Krempler, F.6    Paulweber, B.7    Patsch, W.8
  • 22
    • 0036078870 scopus 로고    scopus 로고
    • The role of uncoupling proteins in pathophysiological states
    • 10.1016/S0006-291X(02)00355-8, 12054495
    • Argiles JM, Busquets S, Lopez-Soriano FJ. The role of uncoupling proteins in pathophysiological states. Biochem Biophys Res Commun 2002, 293(4):1145-1152. 10.1016/S0006-291X(02)00355-8, 12054495.
    • (2002) Biochem Biophys Res Commun , vol.293 , Issue.4 , pp. 1145-1152
    • Argiles, J.M.1    Busquets, S.2    Lopez-Soriano, F.J.3
  • 23
    • 0035994713 scopus 로고    scopus 로고
    • UCP2 and UCP3 in muscle controlling body metabolism
    • Schrauwen P, Hesselink M. UCP2 and UCP3 in muscle controlling body metabolism. J Exp Biol 2002, 205(Pt 15):2275-2285.
    • (2002) J Exp Biol , vol.205 , Issue.PT 15 , pp. 2275-2285
    • Schrauwen, P.1    Hesselink, M.2
  • 24
    • 42949126387 scopus 로고    scopus 로고
    • Mitochondrial uncoupling protein 3 and its role in cardiac- and skeletal muscle metabolism
    • 10.1016/j.physbeh.2007.11.039, 18191161
    • Nabben M, Hoeks J. Mitochondrial uncoupling protein 3 and its role in cardiac- and skeletal muscle metabolism. Physiol Behav 2008, 94(2):259-269. 10.1016/j.physbeh.2007.11.039, 18191161.
    • (2008) Physiol Behav , vol.94 , Issue.2 , pp. 259-269
    • Nabben, M.1    Hoeks, J.2
  • 25
    • 0033406189 scopus 로고    scopus 로고
    • A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians
    • 10.1038/sj.ijo.0801057, 10643679
    • Schrauwen P, Xia J, Walder K, Snitker S, Ravussin E. A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians. Int J Obes Relat Metab Disord 1999, 23(12):1242-1245. 10.1038/sj.ijo.0801057, 10643679.
    • (1999) Int J Obes Relat Metab Disord , vol.23 , Issue.12 , pp. 1242-1245
    • Schrauwen, P.1    Xia, J.2    Walder, K.3    Snitker, S.4    Ravussin, E.5
  • 26
    • 0032933115 scopus 로고    scopus 로고
    • Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians
    • 10.2337/diabetes.48.1.146, 9892236
    • Schrauwen P, Xia J, Bogardus C, Pratley RE, Ravussin E. Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians. Diabetes 1999, 48(1):146-149. 10.2337/diabetes.48.1.146, 9892236.
    • (1999) Diabetes , vol.48 , Issue.1 , pp. 146-149
    • Schrauwen, P.1    Xia, J.2    Bogardus, C.3    Pratley, R.E.4    Ravussin, E.5
  • 28
    • 0033735893 scopus 로고    scopus 로고
    • An uncoupling protein 3 gene polymorphism associated with a lower risk of developing Type II diabetes and with atherogenic lipid profile in a French cohort
    • 10.1007/s001250051549, 11126413
    • Meirhaeghe A, Amouyel P, Helbecque N, Cottel D, Otabe S, Froguel P, Vasseur F. An uncoupling protein 3 gene polymorphism associated with a lower risk of developing Type II diabetes and with atherogenic lipid profile in a French cohort. Diabetologia 2000, 43(11):1424-1428. 10.1007/s001250051549, 11126413.
    • (2000) Diabetologia , vol.43 , Issue.11 , pp. 1424-1428
    • Meirhaeghe, A.1    Amouyel, P.2    Helbecque, N.3    Cottel, D.4    Otabe, S.5    Froguel, P.6    Vasseur, F.7
  • 29
    • 0034003721 scopus 로고    scopus 로고
    • A genetic variation in the 5' flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity
    • 10.1007/s001250050037, 10753049
    • Otabe S, Clement K, Dina C, Pelloux V, Guy-Grand B, Froguel P, Vasseur F. A genetic variation in the 5' flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity. Diabetologia 2000, 43(2):245-249. 10.1007/s001250050037, 10753049.
    • (2000) Diabetologia , vol.43 , Issue.2 , pp. 245-249
    • Otabe, S.1    Clement, K.2    Dina, C.3    Pelloux, V.4    Guy-Grand, B.5    Froguel, P.6    Vasseur, F.7
  • 30
    • 25144493070 scopus 로고    scopus 로고
    • Linkage and association analyses of the UCP3 gene with obesity phenotypes in Caucasian families
    • 10.1152/physiolgenomics.00031.2005, 15870396
    • Liu YJ, Liu PY, Long J, Lu Y, Elze L, Recker RR, Deng HW. Linkage and association analyses of the UCP3 gene with obesity phenotypes in Caucasian families. Physiol Genomics 2005, 22(2):197-203. 10.1152/physiolgenomics.00031.2005, 15870396.
    • (2005) Physiol Genomics , vol.22 , Issue.2 , pp. 197-203
    • Liu, Y.J.1    Liu, P.Y.2    Long, J.3    Lu, Y.4    Elze, L.5    Recker, R.R.6    Deng, H.W.7
  • 31
    • 0035074953 scopus 로고    scopus 로고
    • Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population
    • 10.1038/sj.ijo.0801584, 11319649
    • Halsall DJ, Luan J, Saker P, Huxtable S, Farooqi IS, Keogh J, Wareham NJ, O'Rahilly S. Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population. Int J Obes Relat Metab Disord 2001, 25(4):472-477. 10.1038/sj.ijo.0801584, 11319649.
    • (2001) Int J Obes Relat Metab Disord , vol.25 , Issue.4 , pp. 472-477
    • Halsall, D.J.1    Luan, J.2    Saker, P.3    Huxtable, S.4    Farooqi, I.S.5    Keogh, J.6    Wareham, N.J.7    O'Rahilly, S.8
  • 32
    • 38749103590 scopus 로고    scopus 로고
    • The common -55 C/T polymorphism in the promoter region of the uncoupling protein 3 gene reduces prevalence of obesity and elevates serum high-density lipoprotein cholesterol levels in the general Japanese population
    • 10.1016/j.metabol.2007.10.019, 18249216
    • Hamada T, Kotani K, Fujiwara S, Sano Y, Domichi M, Tsuzaki K, Sakane N. The common -55 C/T polymorphism in the promoter region of the uncoupling protein 3 gene reduces prevalence of obesity and elevates serum high-density lipoprotein cholesterol levels in the general Japanese population. Metabolism 2008, 57(3):410-415. 10.1016/j.metabol.2007.10.019, 18249216.
    • (2008) Metabolism , vol.57 , Issue.3 , pp. 410-415
    • Hamada, T.1    Kotani, K.2    Fujiwara, S.3    Sano, Y.4    Domichi, M.5    Tsuzaki, K.6    Sakane, N.7
  • 33
    • 43149118987 scopus 로고    scopus 로고
    • Variations in the uncoupling protein-3 gene are associated with specific obesity phenotypes
    • 10.1530/EJE-07-0834, 18426825
    • van Abeelen AF, de Krom M, Hendriks J, Grobbee DE, Adan RA, Schouw YT. Variations in the uncoupling protein-3 gene are associated with specific obesity phenotypes. Eur J Endocrinol 2008, 158(5):669-676. 10.1530/EJE-07-0834, 18426825.
    • (2008) Eur J Endocrinol , vol.158 , Issue.5 , pp. 669-676
    • van Abeelen, A.F.1    de Krom, M.2    Hendriks, J.3    Grobbee, D.E.4    Adan, R.A.5    Schouw, Y.T.6
  • 34
    • 33646487792 scopus 로고    scopus 로고
    • The effects of uncoupling protein 3 haplotypes on obesity phenotypes and very low-energy diet-induced changes among overweight Korean female subjects
    • 10.1016/j.metabol.2005.11.012, 16631432
    • Cha MH, Shin HD, Kim KS, Lee BH, Yoon Y. The effects of uncoupling protein 3 haplotypes on obesity phenotypes and very low-energy diet-induced changes among overweight Korean female subjects. Metabolism 2006, 55(5):578-586. 10.1016/j.metabol.2005.11.012, 16631432.
    • (2006) Metabolism , vol.55 , Issue.5 , pp. 578-586
    • Cha, M.H.1    Shin, H.D.2    Kim, K.S.3    Lee, B.H.4    Yoon, Y.5
  • 35
    • 17744363274 scopus 로고    scopus 로고
    • A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population
    • 10.1210/jc.86.3.1398, 11238538
    • Dalgaard LT, Sorensen TI, Drivsholm T, Borch-Johnsen K, Andersen T, Hansen T, Pedersen O. A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population. J Clin Endocrinol Metab 2001, 86(3):1398-1402. 10.1210/jc.86.3.1398, 11238538.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.3 , pp. 1398-1402
    • Dalgaard, L.T.1    Sorensen, T.I.2    Drivsholm, T.3    Borch-Johnsen, K.4    Andersen, T.5    Hansen, T.6    Pedersen, O.7
  • 36
    • 34548840813 scopus 로고    scopus 로고
    • Lack of association of -55CT polymorphism of UCP3 gene with fat distribution in obese patients
    • 10.1159/000107685, 17728536
    • de Luis DA, Aller R, Izaola O, Gonzalez Sagrado M, Conde R, Perez Castrillon JL. Lack of association of -55CT polymorphism of UCP3 gene with fat distribution in obese patients. Ann Nutr Metab 2007, 51(4):374-378. 10.1159/000107685, 17728536.
    • (2007) Ann Nutr Metab , vol.51 , Issue.4 , pp. 374-378
    • de Luis, D.A.1    Aller, R.2    Izaola, O.3    Gonzalez Sagrado, M.4    Conde, R.5    Perez Castrillon, J.L.6
  • 40
    • 0034435115 scopus 로고    scopus 로고
    • Assessment of insulin sensitivity and beta-cell function from measurements in the fasting state and during an oral glucose tolerance test
    • 10.1007/s001250051561, 11151759
    • Albareda M, Rodriguez-Espinosa J, Murugo M, de Leiva A, Corcoy R. Assessment of insulin sensitivity and beta-cell function from measurements in the fasting state and during an oral glucose tolerance test. Diabetologia 2000, 43(12):1507-1511. 10.1007/s001250051561, 11151759.
    • (2000) Diabetologia , vol.43 , Issue.12 , pp. 1507-1511
    • Albareda, M.1    Rodriguez-Espinosa, J.2    Murugo, M.3    de Leiva, A.4    Corcoy, R.5
  • 41
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18(6):499-502.
    • (1972) Clin Chem , vol.18 , Issue.6 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 44
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • 10.1093/bioinformatics/bth457, 15297300
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21(2):263-265. 10.1093/bioinformatics/bth457, 15297300.
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 45
    • 1642313766 scopus 로고    scopus 로고
    • A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm
    • 10.1046/j.1529-8817.2003.00085.x, 15008795
    • Tregouet DA, Escolano S, Tiret L, Mallet A, Golmard JL. A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm. Ann Hum Genet 2004, 68(Pt 2):165-177. 10.1046/j.1529-8817.2003.00085.x, 15008795.
    • (2004) Ann Hum Genet , vol.68 , Issue.PT 2 , pp. 165-177
    • Tregouet, D.A.1    Escolano, S.2    Tiret, L.3    Mallet, A.4    Golmard, J.L.5
  • 46
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • 10.1073/pnas.1530509100, 170937, 12883005
    • Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003, 100(16):9440-9445. 10.1073/pnas.1530509100, 170937, 12883005.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.16 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 47
    • 33745312588 scopus 로고    scopus 로고
    • Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men
    • 10.2337/db05-1645, 16644712
    • Gable DR, Stephens JW, Cooper JA, Miller GJ, Humphries SE. Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men. Diabetes 2006, 55(5):1504-1511. 10.2337/db05-1645, 16644712.
    • (2006) Diabetes , vol.55 , Issue.5 , pp. 1504-1511
    • Gable, D.R.1    Stephens, J.W.2    Cooper, J.A.3    Miller, G.J.4    Humphries, S.E.5
  • 48
    • 1842427206 scopus 로고    scopus 로고
    • Genetic variation in uncoupling protein 3 is associated with dietary intake and body composition in females
    • 10.1016/j.metabol.2003.11.019, 15045692
    • Damcott CM, Feingold E, Moffett SP, Barmada MM, Marshall JA, Hamman RF, Ferrell RE. Genetic variation in uncoupling protein 3 is associated with dietary intake and body composition in females. Metabolism 2004, 53(4):458-464. 10.1016/j.metabol.2003.11.019, 15045692.
    • (2004) Metabolism , vol.53 , Issue.4 , pp. 458-464
    • Damcott, C.M.1    Feingold, E.2    Moffett, S.P.3    Barmada, M.M.4    Marshall, J.A.5    Hamman, R.F.6    Ferrell, R.E.7
  • 50
    • 44649092702 scopus 로고    scopus 로고
    • Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis
    • 10.1016/j.jclinepi.2007.08.012, 18359190
    • Lee CM, Huxley RR, Wildman RP, Woodward M. Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis. J Clin Epidemiol 2008, 61(7):646-653. 10.1016/j.jclinepi.2007.08.012, 18359190.
    • (2008) J Clin Epidemiol , vol.61 , Issue.7 , pp. 646-653
    • Lee, C.M.1    Huxley, R.R.2    Wildman, R.P.3    Woodward, M.4
  • 52
    • 14044254272 scopus 로고    scopus 로고
    • The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy
    • 10.1210/jc.2004-1072, 15562023
    • Bulotta A, Ludovico O, Coco A, Di Paola R, Quattrone A, Carella M, Pellegrini F, Prudente S, Trischitta V. The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy. J Clin Endocrinol Metab 2005, 90(2):1176-1180. 10.1210/jc.2004-1072, 15562023.
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.2 , pp. 1176-1180
    • Bulotta, A.1    Ludovico, O.2    Coco, A.3    Di Paola, R.4    Quattrone, A.5    Carella, M.6    Pellegrini, F.7    Prudente, S.8    Trischitta, V.9
  • 53
    • 10744222893 scopus 로고    scopus 로고
    • Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients
    • 10.2337/diabetes.53.2.482, 14747301
    • Sasahara M, Nishi M, Kawashima H, Ueda K, Sakagashira S, Furuta H, Matsumoto E, Hanabusa T, Sasaki H, Nanjo K. Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients. Diabetes 2004, 53(2):482-485. 10.2337/diabetes.53.2.482, 14747301.
    • (2004) Diabetes , vol.53 , Issue.2 , pp. 482-485
    • Sasahara, M.1    Nishi, M.2    Kawashima, H.3    Ueda, K.4    Sakagashira, S.5    Furuta, H.6    Matsumoto, E.7    Hanabusa, T.8    Sasaki, H.9    Nanjo, K.10
  • 55
    • 34248385690 scopus 로고    scopus 로고
    • Association of UCP2 and UCP3 gene polymorphisms with serum high-density lipoprotein cholesterol among Korean women
    • 10.1016/j.metabol.2007.01.023, 17512314
    • Cha MH, Kim IC, Kim KS, Kang BK, Choi SM, Yoon Y. Association of UCP2 and UCP3 gene polymorphisms with serum high-density lipoprotein cholesterol among Korean women. Metabolism 2007, 56(6):806-813. 10.1016/j.metabol.2007.01.023, 17512314.
    • (2007) Metabolism , vol.56 , Issue.6 , pp. 806-813
    • Cha, M.H.1    Kim, I.C.2    Kim, K.S.3    Kang, B.K.4    Choi, S.M.5    Yoon, Y.6
  • 56
    • 4043127546 scopus 로고    scopus 로고
    • A polymorphism in the promoter of UCP2 gene modulates lipid levels in patients with type 2 diabetes
    • 10.1016/j.ymgme.2004.06.008, 15308133
    • Reis AF, Dubois-Laforgue D, Bellanne-Chantelot C, Timsit J, Velho G. A polymorphism in the promoter of UCP2 gene modulates lipid levels in patients with type 2 diabetes. Mol Genet Metab 2004, 82(4):339-344. 10.1016/j.ymgme.2004.06.008, 15308133.
    • (2004) Mol Genet Metab , vol.82 , Issue.4 , pp. 339-344
    • Reis, A.F.1    Dubois-Laforgue, D.2    Bellanne-Chantelot, C.3    Timsit, J.4    Velho, G.5
  • 57
    • 0034927069 scopus 로고    scopus 로고
    • Uncoupling protein 2: Adiposity angel and diabetes devil?
    • 10.1038/89877, 11433333
    • O'Rahilly S. Uncoupling protein 2: Adiposity angel and diabetes devil?. Nat Med 2001, 7(7):770-772. 10.1038/89877, 11433333.
    • (2001) Nat Med , vol.7 , Issue.7 , pp. 770-772
    • O'Rahilly, S.1
  • 58
    • 33846813359 scopus 로고    scopus 로고
    • Uncoupling protein-3: clues in an ongoing mitochondrial mystery
    • 10.1096/fj.06-6966rev, 17202247
    • Bezaire V, Seifert EL, Harper ME. Uncoupling protein-3: clues in an ongoing mitochondrial mystery. FASEB J 2007, 21(2):312-324. 10.1096/fj.06-6966rev, 17202247.
    • (2007) FASEB J , vol.21 , Issue.2 , pp. 312-324
    • Bezaire, V.1    Seifert, E.L.2    Harper, M.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.