-
1
-
-
33751269135
-
Regulation of insulin secretion by uncoupling protein
-
Chan CB, Kashemsant N. Regulation of insulin secretion by uncoupling protein. Biochem Soc Trans 2006, 34(Pt 5):802-805.
-
(2006)
Biochem Soc Trans
, vol.34
, Issue.PT 5
, pp. 802-805
-
-
Chan, C.B.1
Kashemsant, N.2
-
2
-
-
0033667705
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
-
10.1038/82565, 11101840
-
Arsenijevic D, Onuma H, Pecqueur C, Raimbault S, Manning BS, Miroux B, Couplan E, Alves-Guerra MC, Goubern M, Surwit R, Bouillaud F, Richard D, Collins S, Ricquier D. Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet 2000, 26(4):435-439. 10.1038/82565, 11101840.
-
(2000)
Nat Genet
, vol.26
, Issue.4
, pp. 435-439
-
-
Arsenijevic, D.1
Onuma, H.2
Pecqueur, C.3
Raimbault, S.4
Manning, B.S.5
Miroux, B.6
Couplan, E.7
Alves-Guerra, M.C.8
Goubern, M.9
Surwit, R.10
Bouillaud, F.11
Richard, D.12
Collins, S.13
Ricquier, D.14
-
3
-
-
33947618988
-
Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action
-
10.1096/fj.06-7148com, 17209127
-
De Souza CT, Araujo EP, Stoppiglia LF, Pauli JR, Ropelle E, Rocco SA, Marin RM, Franchini KG, Carvalheira JB, Saad MJ, Boschero AC, Carneiro EM, Velloso LA. Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action. FASEB J 2007, 21(4):1153-1163. 10.1096/fj.06-7148com, 17209127.
-
(2007)
FASEB J
, vol.21
, Issue.4
, pp. 1153-1163
-
-
De Souza, C.T.1
Araujo, E.P.2
Stoppiglia, L.F.3
Pauli, J.R.4
Ropelle, E.5
Rocco, S.A.6
Marin, R.M.7
Franchini, K.G.8
Carvalheira, J.B.9
Saad, M.J.10
Boschero, A.C.11
Carneiro, E.M.12
Velloso, L.A.13
-
4
-
-
0035875087
-
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes
-
10.1016/S0092-8674(01)00378-6, 11440717
-
Zhang CY, Baffy G, Perret P, Krauss S, Peroni O, Grujic D, Hagen T, Vidal-Puig AJ, Boss O, Kim YB, Zheng XX, Wheeler MB, Shulman GI, Chan CB, Lowell BB. Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. Cell 2001, 105(6):745-755. 10.1016/S0092-8674(01)00378-6, 11440717.
-
(2001)
Cell
, vol.105
, Issue.6
, pp. 745-755
-
-
Zhang, C.Y.1
Baffy, G.2
Perret, P.3
Krauss, S.4
Peroni, O.5
Grujic, D.6
Hagen, T.7
Vidal-Puig, A.J.8
Boss, O.9
Kim, Y.B.10
Zheng, X.X.11
Wheeler, M.B.12
Shulman, G.I.13
Chan, C.B.14
Lowell, B.B.15
-
5
-
-
0031019249
-
Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia
-
10.1038/ng0397-269, 9054939
-
Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levi-Meyrueis C, Bouillaud F, Seldin MF, Surwit RS, Ricquier D, Warden CH. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet 1997, 15(3):269-272. 10.1038/ng0397-269, 9054939.
-
(1997)
Nat Genet
, vol.15
, Issue.3
, pp. 269-272
-
-
Fleury, C.1
Neverova, M.2
Collins, S.3
Raimbault, S.4
Champigny, O.5
Levi-Meyrueis, C.6
Bouillaud, F.7
Seldin, M.F.8
Surwit, R.S.9
Ricquier, D.10
Warden, C.H.11
-
6
-
-
0030803678
-
The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts
-
10.1074/jbc.272.41.25433, 9325252
-
Solanes G, Vidal-Puig A, Grujic D, Flier JS, Lowell BB. The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts. J Biol Chem 1997, 272(41):25433-25436. 10.1074/jbc.272.41.25433, 9325252.
-
(1997)
J Biol Chem
, vol.272
, Issue.41
, pp. 25433-25436
-
-
Solanes, G.1
Vidal-Puig, A.2
Grujic, D.3
Flier, J.S.4
Lowell, B.B.5
-
7
-
-
35548952185
-
Meta-Analysis of Genome-wide Linkage Studies in BMI and Obesity
-
10.1038/oby.2007.269, 17890495
-
Saunders CL, Chiodini BD, Sham P, Lewis CM, Abkevich V, Adeyemo AA, de Andrade M, Arya R, Berenson GS, Blangero J, Boehnke M, Borecki IB, Chagnon YC, Chen W, Comuzzie AG, Deng HW, Duggirala R, Feitosa MF, Froguel P, Hanson RL, Hebebrand J, Huezo-Dias P, Kissebah AH, Li W, Luke A, Martin LJ, Nash M, Ohman M, Palmer LJ, Peltonen L, Perola M, Price RA, Redline S, Srinivasan SR, Stern MP, Stone S, Stringham H, Turner S, Wijmenga C, A Collier D. Meta-Analysis of Genome-wide Linkage Studies in BMI and Obesity. Obesity (Silver Spring) 2007, 15(9):2263-2275. 10.1038/oby.2007.269, 17890495.
-
(2007)
Obesity (Silver Spring)
, vol.15
, Issue.9
, pp. 2263-2275
-
-
Saunders, C.L.1
Chiodini, B.D.2
Sham, P.3
Lewis, C.M.4
Abkevich, V.5
Adeyemo, A.A.6
de Andrade, M.7
Arya, R.8
Berenson, G.S.9
Blangero, J.10
Boehnke, M.11
Borecki, I.B.12
Chagnon, Y.C.13
Chen, W.14
Comuzzie, A.G.15
Deng, H.W.16
Duggirala, R.17
Feitosa, M.F.18
Froguel, P.19
Hanson, R.L.20
Hebebrand, J.21
Huezo-Dias, P.22
Kissebah, A.H.23
Li, W.24
Luke, A.25
Martin, L.J.26
Nash, M.27
Ohman, M.28
Palmer, L.J.29
Peltonen, L.30
Perola, M.31
Price, R.A.32
Redline, S.33
Srinivasan, S.R.34
Stern, M.P.35
Stone, S.36
Stringham, H.37
Turner, S.38
Wijmenga, C.39
A Collier, D.40
more..
-
8
-
-
7344220905
-
Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians
-
10.1093/hmg/7.9.1431, 9700198
-
Walder K, Norman RA, Hanson RL, Schrauwen P, Neverova M, Jenkinson CP, Easlick J, Warden CH, Pecqueur C, Raimbault S, Ricquier D, Silver MH, Shuldiner AR, Solanes G, Lowell BB, Chung WK, Leibel RL, Pratley R, Ravussin E. Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians. Hum Mol Genet 1998, 7(9):1431-1435. 10.1093/hmg/7.9.1431, 9700198.
-
(1998)
Hum Mol Genet
, vol.7
, Issue.9
, pp. 1431-1435
-
-
Walder, K.1
Norman, R.A.2
Hanson, R.L.3
Schrauwen, P.4
Neverova, M.5
Jenkinson, C.P.6
Easlick, J.7
Warden, C.H.8
Pecqueur, C.9
Raimbault, S.10
Ricquier, D.11
Silver, M.H.12
Shuldiner, A.R.13
Solanes, G.14
Lowell, B.B.15
Chung, W.K.16
Leibel, R.L.17
Pratley, R.18
Ravussin, E.19
-
9
-
-
15444342187
-
Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity
-
10.1210/jc.83.8.2800, 9709950
-
Kubota T, Mori H, Tamori Y, Okazawa H, Fukuda T, Miki M, Ito C, Fleury C, Bouillaud F, Kasuga M. Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity. J Clin Endocrinol Metab 1998, 83(8):2800-2804. 10.1210/jc.83.8.2800, 9709950.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, Issue.8
, pp. 2800-2804
-
-
Kubota, T.1
Mori, H.2
Tamori, Y.3
Okazawa, H.4
Fukuda, T.5
Miki, M.6
Ito, C.7
Fleury, C.8
Bouillaud, F.9
Kasuga, M.10
-
10
-
-
0032989496
-
An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes
-
10.1007/s001250051216, 10382588
-
Cassell PG, Neverova M, Janmohamed S, Uwakwe N, Qureshi A, McCarthy MI, Saker PJ, Albon L, Kopelman P, Noonan K, Easlick J, Ramachandran A, Snehalatha C, Pecqueur C, Ricquier D, Warden C, Hitman GA. An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes. Diabetologia 1999, 42(6):688-692. 10.1007/s001250051216, 10382588.
-
(1999)
Diabetologia
, vol.42
, Issue.6
, pp. 688-692
-
-
Cassell, P.G.1
Neverova, M.2
Janmohamed, S.3
Uwakwe, N.4
Qureshi, A.5
McCarthy, M.I.6
Saker, P.J.7
Albon, L.8
Kopelman, P.9
Noonan, K.10
Easlick, J.11
Ramachandran, A.12
Snehalatha, C.13
Pecqueur, C.14
Ricquier, D.15
Warden, C.16
Hitman, G.A.17
-
11
-
-
0034766937
-
Genetic variation at the uncoupling protein 1, 2 and 3 loci and the response to long-term overfeeding
-
10.1038/sj.ejcn.1601261, 11641751
-
Ukkola O, Tremblay A, Sun G, Chagnon YC, Bouchard C. Genetic variation at the uncoupling protein 1, 2 and 3 loci and the response to long-term overfeeding. Eur J Clin Nutr 2001, 55(11):1008-1015. 10.1038/sj.ejcn.1601261, 11641751.
-
(2001)
Eur J Clin Nutr
, vol.55
, Issue.11
, pp. 1008-1015
-
-
Ukkola, O.1
Tremblay, A.2
Sun, G.3
Chagnon, Y.C.4
Bouchard, C.5
-
12
-
-
0037145722
-
Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome
-
Rosmond R, Bouchard C, Bjorntorp P. Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome. Biochim Biophys Acta 2002, 1588(2):103-105.
-
(2002)
Biochim Biophys Acta
, vol.1588
, Issue.2
, pp. 103-105
-
-
Rosmond, R.1
Bouchard, C.2
Bjorntorp, P.3
-
13
-
-
0346787545
-
Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion
-
10.1152/ajpendo.00231.2003, 12915397
-
Wang H, Chu WS, Lu T, Hasstedt SJ, Kern PA, Elbein SC. Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion. Am J Physiol Endocrinol Metab 2004, 286(1):E1-7. 10.1152/ajpendo.00231.2003, 12915397.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
, Issue.1
-
-
Wang, H.1
Chu, W.S.2
Lu, T.3
Hasstedt, S.J.4
Kern, P.A.5
Elbein, S.C.6
-
14
-
-
0036830548
-
A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans
-
10.2337/diabetes.51.11.3331, 12401727
-
Krempler F, Esterbauer H, Weitgasser R, Ebenbichler C, Patsch JR, Miller K, Xie M, Linnemayr V, Oberkofler H, Patsch W. A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans. Diabetes 2002, 51(11):3331-3335. 10.2337/diabetes.51.11.3331, 12401727.
-
(2002)
Diabetes
, vol.51
, Issue.11
, pp. 3331-3335
-
-
Krempler, F.1
Esterbauer, H.2
Weitgasser, R.3
Ebenbichler, C.4
Patsch, J.R.5
Miller, K.6
Xie, M.7
Linnemayr, V.8
Oberkofler, H.9
Patsch, W.10
-
15
-
-
12444292715
-
A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects
-
10.2337/diabetes.52.5.1280, 12716765
-
Sesti G, Cardellini M, Marini MA, Frontoni S, D'Adamo M, Del Guerra S, Lauro D, De Nicolais P, Sbraccia P, Del Prato S, Gambardella S, Federici M, Marchetti P, Lauro R. A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects. Diabetes 2003, 52(5):1280-1283. 10.2337/diabetes.52.5.1280, 12716765.
-
(2003)
Diabetes
, vol.52
, Issue.5
, pp. 1280-1283
-
-
Sesti, G.1
Cardellini, M.2
Marini, M.A.3
Frontoni, S.4
D'Adamo, M.5
Del Guerra, S.6
Lauro, D.7
De Nicolais, P.8
Sbraccia, P.9
Del Prato, S.10
Gambardella, S.11
Federici, M.12
Marchetti, P.13
Lauro, R.14
-
16
-
-
0347990596
-
The common -866 g/a polymorphism in the promoter of uncoupling protein 2 is associated with increased carbohydrate and decreased lipid oxidation in juvenile obesity
-
10.2337/diabetes.53.1.235, 14693721
-
Le Fur S, Le Stunff C, Dos Santos C, Bougneres P. The common -866 g/a polymorphism in the promoter of uncoupling protein 2 is associated with increased carbohydrate and decreased lipid oxidation in juvenile obesity. Diabetes 2004, 53(1):235-239. 10.2337/diabetes.53.1.235, 14693721.
-
(2004)
Diabetes
, vol.53
, Issue.1
, pp. 235-239
-
-
Le Fur, S.1
Le Stunff, C.2
Dos Santos, C.3
Bougneres, P.4
-
17
-
-
0034972150
-
A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans
-
10.1038/88911, 11381268
-
Esterbauer H, Schneitler C, Oberkofler H, Ebenbichler C, Paulweber B, Sandhofer F, Ladurner G, Hell E, Strosberg AD, Patsch JR, Krempler F, Patsch W. A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans. Nat Genet 2001, 28(2):178-183. 10.1038/88911, 11381268.
-
(2001)
Nat Genet
, vol.28
, Issue.2
, pp. 178-183
-
-
Esterbauer, H.1
Schneitler, C.2
Oberkofler, H.3
Ebenbichler, C.4
Paulweber, B.5
Sandhofer, F.6
Ladurner, G.7
Hell, E.8
Strosberg, A.D.9
Patsch, J.R.10
Krempler, F.11
Patsch, W.12
-
18
-
-
1942424804
-
Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2
-
10.1016/j.ehj.2004.01.007, 15039126
-
Dhamrait SS, Stephens JW, Cooper JA, Acharya J, Mani AR, Moore K, Miller GJ, Humphries SE, Hurel SJ, Montgomery HE. Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2. Eur Heart J 2004, 25(6):468-475. 10.1016/j.ehj.2004.01.007, 15039126.
-
(2004)
Eur Heart J
, vol.25
, Issue.6
, pp. 468-475
-
-
Dhamrait, S.S.1
Stephens, J.W.2
Cooper, J.A.3
Acharya, J.4
Mani, A.R.5
Moore, K.6
Miller, G.J.7
Humphries, S.E.8
Hurel, S.J.9
Montgomery, H.E.10
-
19
-
-
0034883804
-
Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes
-
10.1007/s001250100596, 11484071
-
Dalgaard LT, Pedersen O. Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes. Diabetologia 2001, 44(8):946-965. 10.1007/s001250100596, 11484071.
-
(2001)
Diabetologia
, vol.44
, Issue.8
, pp. 946-965
-
-
Dalgaard, L.T.1
Pedersen, O.2
-
20
-
-
27744550916
-
Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians
-
10.1007/s00125-005-1934-9, 16167150
-
Kovacs P, Ma L, Hanson RL, Franks P, Stumvoll M, Bogardus C, Baier LJ. Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians. Diabetologia 2005, 48(11):2292-2295. 10.1007/s00125-005-1934-9, 16167150.
-
(2005)
Diabetologia
, vol.48
, Issue.11
, pp. 2292-2295
-
-
Kovacs, P.1
Ma, L.2
Hanson, R.L.3
Franks, P.4
Stumvoll, M.5
Bogardus, C.6
Baier, L.J.7
-
21
-
-
14644390316
-
Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women
-
10.1161/01.ATV.0000153141.42033.22, 15604415
-
Oberkofler H, Iglseder B, Klein K, Unger J, Haltmayer M, Krempler F, Paulweber B, Patsch W. Associations of the UCP2 gene locus with asymptomatic carotid atherosclerosis in middle-aged women. Arterioscler Thromb Vasc Biol 2005, 25(3):604-610. 10.1161/01.ATV.0000153141.42033.22, 15604415.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, Issue.3
, pp. 604-610
-
-
Oberkofler, H.1
Iglseder, B.2
Klein, K.3
Unger, J.4
Haltmayer, M.5
Krempler, F.6
Paulweber, B.7
Patsch, W.8
-
22
-
-
0036078870
-
The role of uncoupling proteins in pathophysiological states
-
10.1016/S0006-291X(02)00355-8, 12054495
-
Argiles JM, Busquets S, Lopez-Soriano FJ. The role of uncoupling proteins in pathophysiological states. Biochem Biophys Res Commun 2002, 293(4):1145-1152. 10.1016/S0006-291X(02)00355-8, 12054495.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, Issue.4
, pp. 1145-1152
-
-
Argiles, J.M.1
Busquets, S.2
Lopez-Soriano, F.J.3
-
23
-
-
0035994713
-
UCP2 and UCP3 in muscle controlling body metabolism
-
Schrauwen P, Hesselink M. UCP2 and UCP3 in muscle controlling body metabolism. J Exp Biol 2002, 205(Pt 15):2275-2285.
-
(2002)
J Exp Biol
, vol.205
, Issue.PT 15
, pp. 2275-2285
-
-
Schrauwen, P.1
Hesselink, M.2
-
24
-
-
42949126387
-
Mitochondrial uncoupling protein 3 and its role in cardiac- and skeletal muscle metabolism
-
10.1016/j.physbeh.2007.11.039, 18191161
-
Nabben M, Hoeks J. Mitochondrial uncoupling protein 3 and its role in cardiac- and skeletal muscle metabolism. Physiol Behav 2008, 94(2):259-269. 10.1016/j.physbeh.2007.11.039, 18191161.
-
(2008)
Physiol Behav
, vol.94
, Issue.2
, pp. 259-269
-
-
Nabben, M.1
Hoeks, J.2
-
25
-
-
0033406189
-
A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians
-
10.1038/sj.ijo.0801057, 10643679
-
Schrauwen P, Xia J, Walder K, Snitker S, Ravussin E. A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians. Int J Obes Relat Metab Disord 1999, 23(12):1242-1245. 10.1038/sj.ijo.0801057, 10643679.
-
(1999)
Int J Obes Relat Metab Disord
, vol.23
, Issue.12
, pp. 1242-1245
-
-
Schrauwen, P.1
Xia, J.2
Walder, K.3
Snitker, S.4
Ravussin, E.5
-
26
-
-
0032933115
-
Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians
-
10.2337/diabetes.48.1.146, 9892236
-
Schrauwen P, Xia J, Bogardus C, Pratley RE, Ravussin E. Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians. Diabetes 1999, 48(1):146-149. 10.2337/diabetes.48.1.146, 9892236.
-
(1999)
Diabetes
, vol.48
, Issue.1
, pp. 146-149
-
-
Schrauwen, P.1
Xia, J.2
Bogardus, C.3
Pratley, R.E.4
Ravussin, E.5
-
27
-
-
0038458975
-
Uncoupling protein 1 and 3 polymorphisms are associated with waist-to-hip ratio
-
Herrmann SM, Wang JG, Staessen JA, Kertmen E, Schmidt-Petersen K, Zidek W, Paul M, Brand E. Uncoupling protein 1 and 3 polymorphisms are associated with waist-to-hip ratio. J Mol Med 2003, 81(5):327-332.
-
(2003)
J Mol Med
, vol.81
, Issue.5
, pp. 327-332
-
-
Herrmann, S.M.1
Wang, J.G.2
Staessen, J.A.3
Kertmen, E.4
Schmidt-Petersen, K.5
Zidek, W.6
Paul, M.7
Brand, E.8
-
28
-
-
0033735893
-
An uncoupling protein 3 gene polymorphism associated with a lower risk of developing Type II diabetes and with atherogenic lipid profile in a French cohort
-
10.1007/s001250051549, 11126413
-
Meirhaeghe A, Amouyel P, Helbecque N, Cottel D, Otabe S, Froguel P, Vasseur F. An uncoupling protein 3 gene polymorphism associated with a lower risk of developing Type II diabetes and with atherogenic lipid profile in a French cohort. Diabetologia 2000, 43(11):1424-1428. 10.1007/s001250051549, 11126413.
-
(2000)
Diabetologia
, vol.43
, Issue.11
, pp. 1424-1428
-
-
Meirhaeghe, A.1
Amouyel, P.2
Helbecque, N.3
Cottel, D.4
Otabe, S.5
Froguel, P.6
Vasseur, F.7
-
29
-
-
0034003721
-
A genetic variation in the 5' flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity
-
10.1007/s001250050037, 10753049
-
Otabe S, Clement K, Dina C, Pelloux V, Guy-Grand B, Froguel P, Vasseur F. A genetic variation in the 5' flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity. Diabetologia 2000, 43(2):245-249. 10.1007/s001250050037, 10753049.
-
(2000)
Diabetologia
, vol.43
, Issue.2
, pp. 245-249
-
-
Otabe, S.1
Clement, K.2
Dina, C.3
Pelloux, V.4
Guy-Grand, B.5
Froguel, P.6
Vasseur, F.7
-
30
-
-
25144493070
-
Linkage and association analyses of the UCP3 gene with obesity phenotypes in Caucasian families
-
10.1152/physiolgenomics.00031.2005, 15870396
-
Liu YJ, Liu PY, Long J, Lu Y, Elze L, Recker RR, Deng HW. Linkage and association analyses of the UCP3 gene with obesity phenotypes in Caucasian families. Physiol Genomics 2005, 22(2):197-203. 10.1152/physiolgenomics.00031.2005, 15870396.
-
(2005)
Physiol Genomics
, vol.22
, Issue.2
, pp. 197-203
-
-
Liu, Y.J.1
Liu, P.Y.2
Long, J.3
Lu, Y.4
Elze, L.5
Recker, R.R.6
Deng, H.W.7
-
31
-
-
0035074953
-
Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population
-
10.1038/sj.ijo.0801584, 11319649
-
Halsall DJ, Luan J, Saker P, Huxtable S, Farooqi IS, Keogh J, Wareham NJ, O'Rahilly S. Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population. Int J Obes Relat Metab Disord 2001, 25(4):472-477. 10.1038/sj.ijo.0801584, 11319649.
-
(2001)
Int J Obes Relat Metab Disord
, vol.25
, Issue.4
, pp. 472-477
-
-
Halsall, D.J.1
Luan, J.2
Saker, P.3
Huxtable, S.4
Farooqi, I.S.5
Keogh, J.6
Wareham, N.J.7
O'Rahilly, S.8
-
32
-
-
38749103590
-
The common -55 C/T polymorphism in the promoter region of the uncoupling protein 3 gene reduces prevalence of obesity and elevates serum high-density lipoprotein cholesterol levels in the general Japanese population
-
10.1016/j.metabol.2007.10.019, 18249216
-
Hamada T, Kotani K, Fujiwara S, Sano Y, Domichi M, Tsuzaki K, Sakane N. The common -55 C/T polymorphism in the promoter region of the uncoupling protein 3 gene reduces prevalence of obesity and elevates serum high-density lipoprotein cholesterol levels in the general Japanese population. Metabolism 2008, 57(3):410-415. 10.1016/j.metabol.2007.10.019, 18249216.
-
(2008)
Metabolism
, vol.57
, Issue.3
, pp. 410-415
-
-
Hamada, T.1
Kotani, K.2
Fujiwara, S.3
Sano, Y.4
Domichi, M.5
Tsuzaki, K.6
Sakane, N.7
-
33
-
-
43149118987
-
Variations in the uncoupling protein-3 gene are associated with specific obesity phenotypes
-
10.1530/EJE-07-0834, 18426825
-
van Abeelen AF, de Krom M, Hendriks J, Grobbee DE, Adan RA, Schouw YT. Variations in the uncoupling protein-3 gene are associated with specific obesity phenotypes. Eur J Endocrinol 2008, 158(5):669-676. 10.1530/EJE-07-0834, 18426825.
-
(2008)
Eur J Endocrinol
, vol.158
, Issue.5
, pp. 669-676
-
-
van Abeelen, A.F.1
de Krom, M.2
Hendriks, J.3
Grobbee, D.E.4
Adan, R.A.5
Schouw, Y.T.6
-
34
-
-
33646487792
-
The effects of uncoupling protein 3 haplotypes on obesity phenotypes and very low-energy diet-induced changes among overweight Korean female subjects
-
10.1016/j.metabol.2005.11.012, 16631432
-
Cha MH, Shin HD, Kim KS, Lee BH, Yoon Y. The effects of uncoupling protein 3 haplotypes on obesity phenotypes and very low-energy diet-induced changes among overweight Korean female subjects. Metabolism 2006, 55(5):578-586. 10.1016/j.metabol.2005.11.012, 16631432.
-
(2006)
Metabolism
, vol.55
, Issue.5
, pp. 578-586
-
-
Cha, M.H.1
Shin, H.D.2
Kim, K.S.3
Lee, B.H.4
Yoon, Y.5
-
35
-
-
17744363274
-
A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population
-
10.1210/jc.86.3.1398, 11238538
-
Dalgaard LT, Sorensen TI, Drivsholm T, Borch-Johnsen K, Andersen T, Hansen T, Pedersen O. A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population. J Clin Endocrinol Metab 2001, 86(3):1398-1402. 10.1210/jc.86.3.1398, 11238538.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, Issue.3
, pp. 1398-1402
-
-
Dalgaard, L.T.1
Sorensen, T.I.2
Drivsholm, T.3
Borch-Johnsen, K.4
Andersen, T.5
Hansen, T.6
Pedersen, O.7
-
36
-
-
34548840813
-
Lack of association of -55CT polymorphism of UCP3 gene with fat distribution in obese patients
-
10.1159/000107685, 17728536
-
de Luis DA, Aller R, Izaola O, Gonzalez Sagrado M, Conde R, Perez Castrillon JL. Lack of association of -55CT polymorphism of UCP3 gene with fat distribution in obese patients. Ann Nutr Metab 2007, 51(4):374-378. 10.1159/000107685, 17728536.
-
(2007)
Ann Nutr Metab
, vol.51
, Issue.4
, pp. 374-378
-
-
de Luis, D.A.1
Aller, R.2
Izaola, O.3
Gonzalez Sagrado, M.4
Conde, R.5
Perez Castrillon, J.L.6
-
37
-
-
0034033026
-
The Finnish Diabetes Prevention Study
-
Uusitupa M, Louheranta A, Lindström J, Valle T, Sundvall J, Eriksson J, Tuomilehto J. The Finnish Diabetes Prevention Study. Br J Nutr 2000, 83(Suppl 1):S137-42.
-
(2000)
Br J Nutr
, vol.83
, Issue.SUPPL 1
-
-
Uusitupa, M.1
Louheranta, A.2
Lindström, J.3
Valle, T.4
Sundvall, J.5
Eriksson, J.6
Tuomilehto, J.7
-
38
-
-
0032791143
-
Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland. Study design and 1-year interim report on the feasibility of the lifestyle intervention programme
-
10.1007/s001250051229, 10440120
-
Eriksson J, Lindström J, Valle T, Aunola S, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Lauhkonen M, Lehto P, Lehtonen A, Louheranta A, Mannelin M, Martikkala V, Rastas M, Sundvall J, Turpeinen A, Viljanen T, Uusitupa M, Tuomilehto J. Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland. Study design and 1-year interim report on the feasibility of the lifestyle intervention programme. Diabetologia 1999, 42(7):793-801. 10.1007/s001250051229, 10440120.
-
(1999)
Diabetologia
, vol.42
, Issue.7
, pp. 793-801
-
-
Eriksson, J.1
Lindström, J.2
Valle, T.3
Aunola, S.4
Hämäläinen, H.5
Ilanne-Parikka, P.6
Keinänen-Kiukaanniemi, S.7
Laakso, M.8
Lauhkonen, M.9
Lehto, P.10
Lehtonen, A.11
Louheranta, A.12
Mannelin, M.13
Martikkala, V.14
Rastas, M.15
Sundvall, J.16
Turpeinen, A.17
Viljanen, T.18
Uusitupa, M.19
Tuomilehto, J.20
more..
-
39
-
-
0035799806
-
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
-
10.1056/NEJM200105033441801, 11333990
-
Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Rastas M, Salminen V, Uusitupa M, . Finnish Diabetes Prevention Study Group Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001, 344(18):1343-1350. 10.1056/NEJM200105033441801, 11333990.
-
(2001)
N Engl J Med
, vol.344
, Issue.18
, pp. 1343-1350
-
-
Tuomilehto, J.1
Lindström, J.2
Eriksson, J.G.3
Valle, T.T.4
Hämäläinen, H.5
Ilanne-Parikka, P.6
Keinänen-Kiukaanniemi, S.7
Laakso, M.8
Louheranta, A.9
Rastas, M.10
Salminen, V.11
Uusitupa, M.12
-
40
-
-
0034435115
-
Assessment of insulin sensitivity and beta-cell function from measurements in the fasting state and during an oral glucose tolerance test
-
10.1007/s001250051561, 11151759
-
Albareda M, Rodriguez-Espinosa J, Murugo M, de Leiva A, Corcoy R. Assessment of insulin sensitivity and beta-cell function from measurements in the fasting state and during an oral glucose tolerance test. Diabetologia 2000, 43(12):1507-1511. 10.1007/s001250051561, 11151759.
-
(2000)
Diabetologia
, vol.43
, Issue.12
, pp. 1507-1511
-
-
Albareda, M.1
Rodriguez-Espinosa, J.2
Murugo, M.3
de Leiva, A.4
Corcoy, R.5
-
41
-
-
0015348189
-
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
-
Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18(6):499-502.
-
(1972)
Clin Chem
, vol.18
, Issue.6
, pp. 499-502
-
-
Friedewald, W.T.1
Levy, R.I.2
Fredrickson, D.S.3
-
42
-
-
27644439141
-
Efficiency and power in genetic association studies
-
10.1038/ng1669, 16244653
-
de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D. Efficiency and power in genetic association studies. Nat Genet 2005, 37(11):1217-1223. 10.1038/ng1669, 16244653.
-
(2005)
Nat Genet
, vol.37
, Issue.11
, pp. 1217-1223
-
-
de Bakker, P.I.1
Yelensky, R.2
Pe'er, I.3
Gabriel, S.B.4
Daly, M.J.5
Altshuler, D.6
-
43
-
-
0034434968
-
Evidence that single nucleotide polymorphism in the uncoupling protein 3 (UCP3) gene influences fat distribution in women of European and Asian origin
-
10.1007/s001250051569, 11151767
-
Cassell PG, Saker PJ, Huxtable SJ, Kousta E, Jackson AE, Hattersley AT, Frayling TM, Walker M, Kopelman PG, Ramachandran A, Snehelatha C, Hitman GA, McCarthy MI. Evidence that single nucleotide polymorphism in the uncoupling protein 3 (UCP3) gene influences fat distribution in women of European and Asian origin. Diabetologia 2000, 43(12):1558-1564. 10.1007/s001250051569, 11151767.
-
(2000)
Diabetologia
, vol.43
, Issue.12
, pp. 1558-1564
-
-
Cassell, P.G.1
Saker, P.J.2
Huxtable, S.J.3
Kousta, E.4
Jackson, A.E.5
Hattersley, A.T.6
Frayling, T.M.7
Walker, M.8
Kopelman, P.G.9
Ramachandran, A.10
Snehelatha, C.11
Hitman, G.A.12
McCarthy, M.I.13
-
44
-
-
13444269543
-
Haploview: analysis and visualization of LD and haplotype maps
-
10.1093/bioinformatics/bth457, 15297300
-
Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21(2):263-265. 10.1093/bioinformatics/bth457, 15297300.
-
(2005)
Bioinformatics
, vol.21
, Issue.2
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
45
-
-
1642313766
-
A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm
-
10.1046/j.1529-8817.2003.00085.x, 15008795
-
Tregouet DA, Escolano S, Tiret L, Mallet A, Golmard JL. A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm. Ann Hum Genet 2004, 68(Pt 2):165-177. 10.1046/j.1529-8817.2003.00085.x, 15008795.
-
(2004)
Ann Hum Genet
, vol.68
, Issue.PT 2
, pp. 165-177
-
-
Tregouet, D.A.1
Escolano, S.2
Tiret, L.3
Mallet, A.4
Golmard, J.L.5
-
46
-
-
0042424602
-
Statistical significance for genomewide studies
-
10.1073/pnas.1530509100, 170937, 12883005
-
Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003, 100(16):9440-9445. 10.1073/pnas.1530509100, 170937, 12883005.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.16
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
47
-
-
33745312588
-
Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men
-
10.2337/db05-1645, 16644712
-
Gable DR, Stephens JW, Cooper JA, Miller GJ, Humphries SE. Variation in the UCP2-UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged men. Diabetes 2006, 55(5):1504-1511. 10.2337/db05-1645, 16644712.
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1504-1511
-
-
Gable, D.R.1
Stephens, J.W.2
Cooper, J.A.3
Miller, G.J.4
Humphries, S.E.5
-
48
-
-
1842427206
-
Genetic variation in uncoupling protein 3 is associated with dietary intake and body composition in females
-
10.1016/j.metabol.2003.11.019, 15045692
-
Damcott CM, Feingold E, Moffett SP, Barmada MM, Marshall JA, Hamman RF, Ferrell RE. Genetic variation in uncoupling protein 3 is associated with dietary intake and body composition in females. Metabolism 2004, 53(4):458-464. 10.1016/j.metabol.2003.11.019, 15045692.
-
(2004)
Metabolism
, vol.53
, Issue.4
, pp. 458-464
-
-
Damcott, C.M.1
Feingold, E.2
Moffett, S.P.3
Barmada, M.M.4
Marshall, J.A.5
Hamman, R.F.6
Ferrell, R.E.7
-
49
-
-
44849093847
-
Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk
-
10.1161/ATVBAHA.107.159228, 18356555
-
Despres JP, Lemieux I, Bergeron J, Pibarot P, Mathieu P, Larose E, Rodes-Cabau J, Bertrand OF, Poirier P. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol 2008, 28(6):1039-1049. 10.1161/ATVBAHA.107.159228, 18356555.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, Issue.6
, pp. 1039-1049
-
-
Despres, J.P.1
Lemieux, I.2
Bergeron, J.3
Pibarot, P.4
Mathieu, P.5
Larose, E.6
Rodes-Cabau, J.7
Bertrand, O.F.8
Poirier, P.9
-
50
-
-
44649092702
-
Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis
-
10.1016/j.jclinepi.2007.08.012, 18359190
-
Lee CM, Huxley RR, Wildman RP, Woodward M. Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis. J Clin Epidemiol 2008, 61(7):646-653. 10.1016/j.jclinepi.2007.08.012, 18359190.
-
(2008)
J Clin Epidemiol
, vol.61
, Issue.7
, pp. 646-653
-
-
Lee, C.M.1
Huxley, R.R.2
Wildman, R.P.3
Woodward, M.4
-
51
-
-
42449098483
-
The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men
-
10.2337/db07-1292, 18192542
-
Cheurfa N, Dubois-Laforgue D, Ferrarezi DA, Reis AF, Brenner GM, Bouche C, Le Feuvre C, Fumeron F, Timsit J, Marre M, Velho G. The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men. Diabetes 2008, 57(4):1063-1068. 10.2337/db07-1292, 18192542.
-
(2008)
Diabetes
, vol.57
, Issue.4
, pp. 1063-1068
-
-
Cheurfa, N.1
Dubois-Laforgue, D.2
Ferrarezi, D.A.3
Reis, A.F.4
Brenner, G.M.5
Bouche, C.6
Le Feuvre, C.7
Fumeron, F.8
Timsit, J.9
Marre, M.10
Velho, G.11
-
52
-
-
14044254272
-
The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy
-
10.1210/jc.2004-1072, 15562023
-
Bulotta A, Ludovico O, Coco A, Di Paola R, Quattrone A, Carella M, Pellegrini F, Prudente S, Trischitta V. The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy. J Clin Endocrinol Metab 2005, 90(2):1176-1180. 10.1210/jc.2004-1072, 15562023.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.2
, pp. 1176-1180
-
-
Bulotta, A.1
Ludovico, O.2
Coco, A.3
Di Paola, R.4
Quattrone, A.5
Carella, M.6
Pellegrini, F.7
Prudente, S.8
Trischitta, V.9
-
53
-
-
10744222893
-
Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients
-
10.2337/diabetes.53.2.482, 14747301
-
Sasahara M, Nishi M, Kawashima H, Ueda K, Sakagashira S, Furuta H, Matsumoto E, Hanabusa T, Sasaki H, Nanjo K. Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients. Diabetes 2004, 53(2):482-485. 10.2337/diabetes.53.2.482, 14747301.
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 482-485
-
-
Sasahara, M.1
Nishi, M.2
Kawashima, H.3
Ueda, K.4
Sakagashira, S.5
Furuta, H.6
Matsumoto, E.7
Hanabusa, T.8
Sasaki, H.9
Nanjo, K.10
-
54
-
-
3042698328
-
The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes
-
10.2337/diabetes.53.7.1905, 15220218
-
D'Adamo M, Perego L, Cardellini M, Marini MA, Frontoni S, Andreozzi F, Sciacqua A, Lauro D, Sbraccia P, Federici M, Paganelli M, Pontiroli AE, Lauro R, Perticone F, Folli F, Sesti G. The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes. Diabetes 2004, 53(7):1905-1910. 10.2337/diabetes.53.7.1905, 15220218.
-
(2004)
Diabetes
, vol.53
, Issue.7
, pp. 1905-1910
-
-
D'Adamo, M.1
Perego, L.2
Cardellini, M.3
Marini, M.A.4
Frontoni, S.5
Andreozzi, F.6
Sciacqua, A.7
Lauro, D.8
Sbraccia, P.9
Federici, M.10
Paganelli, M.11
Pontiroli, A.E.12
Lauro, R.13
Perticone, F.14
Folli, F.15
Sesti, G.16
-
55
-
-
34248385690
-
Association of UCP2 and UCP3 gene polymorphisms with serum high-density lipoprotein cholesterol among Korean women
-
10.1016/j.metabol.2007.01.023, 17512314
-
Cha MH, Kim IC, Kim KS, Kang BK, Choi SM, Yoon Y. Association of UCP2 and UCP3 gene polymorphisms with serum high-density lipoprotein cholesterol among Korean women. Metabolism 2007, 56(6):806-813. 10.1016/j.metabol.2007.01.023, 17512314.
-
(2007)
Metabolism
, vol.56
, Issue.6
, pp. 806-813
-
-
Cha, M.H.1
Kim, I.C.2
Kim, K.S.3
Kang, B.K.4
Choi, S.M.5
Yoon, Y.6
-
56
-
-
4043127546
-
A polymorphism in the promoter of UCP2 gene modulates lipid levels in patients with type 2 diabetes
-
10.1016/j.ymgme.2004.06.008, 15308133
-
Reis AF, Dubois-Laforgue D, Bellanne-Chantelot C, Timsit J, Velho G. A polymorphism in the promoter of UCP2 gene modulates lipid levels in patients with type 2 diabetes. Mol Genet Metab 2004, 82(4):339-344. 10.1016/j.ymgme.2004.06.008, 15308133.
-
(2004)
Mol Genet Metab
, vol.82
, Issue.4
, pp. 339-344
-
-
Reis, A.F.1
Dubois-Laforgue, D.2
Bellanne-Chantelot, C.3
Timsit, J.4
Velho, G.5
-
57
-
-
0034927069
-
Uncoupling protein 2: Adiposity angel and diabetes devil?
-
10.1038/89877, 11433333
-
O'Rahilly S. Uncoupling protein 2: Adiposity angel and diabetes devil?. Nat Med 2001, 7(7):770-772. 10.1038/89877, 11433333.
-
(2001)
Nat Med
, vol.7
, Issue.7
, pp. 770-772
-
-
O'Rahilly, S.1
-
58
-
-
33846813359
-
Uncoupling protein-3: clues in an ongoing mitochondrial mystery
-
10.1096/fj.06-6966rev, 17202247
-
Bezaire V, Seifert EL, Harper ME. Uncoupling protein-3: clues in an ongoing mitochondrial mystery. FASEB J 2007, 21(2):312-324. 10.1096/fj.06-6966rev, 17202247.
-
(2007)
FASEB J
, vol.21
, Issue.2
, pp. 312-324
-
-
Bezaire, V.1
Seifert, E.L.2
Harper, M.E.3
|