Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians

Diabetes

Volumn 48, Issue 1, 1999, Pages 146-149

  Schrauwen, Patrick ^b   Xia, James ^a   Bogardus, Clifton ^a   Pratley, Richard E ^a   Ravussin, Eric ^a,c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; ENERGY EXPENDITURE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; INDIAN; MALE; METABOLIC RATE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RACE DIFFERENCE; SKELETAL MUSCLE;

ADULT; BODY COMPOSITION; BODY MASS INDEX; CARRIER PROTEINS; ENERGY METABOLISM; HUMANS; INDIANS, NORTH AMERICAN; ION CHANNELS; MALE; MIDDLE AGED; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; SLEEP;

EID: 0032933115     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.1.146     Document Type: Article

References (22)

1. Ravussin E, Lillioja S, Anderson TE, Christin L, Bogardus C: Determinants of 24-hour energy expenditure in man: methods and results using a respiratory chamber. J Clin Invest 78:1568-1578, 1986
2. Tataranni PA, Ravussin E: Variability in metabolic rate: biological sites of regulation. Int J Obesity 19:S102-S106, 1995
3. Bogardus C, Lillioja S, Ravussin E. Abbott W, Zawadzki JK, Young A, Knowler WC, Jacobowitz R, Moll PP: Familial dependence of the resting metabolic rate. New Engl J Med 315:96-100, 1986
4. Bouchard C, Tremblay A, Nadeau A, Després JP, Thériault G, Boulay MR, Lortie G, Leblanc C, Fournier G: Genetic effect in resting and exercise metabolic rate. Metabolism 38:364-370, 1989
5. Ravussin E, Lillioja S, Knowler WC, Christen L, Freymond D, Abbott WGH, Boyce V, Howard BV, Bogardus C: Reduced rate of energy expenditure as a risk factor for body-weight gain. N Engl J Med 318:467-472, 1988
6. Zurlo F, Larson K, Bogardus C, Ravussin E: Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest 86:1423-1427, 1990
7. Ricquier D, Casteilla L, Bouillaud F: Molecular studies of the uncoupling protein. FASEB J 5:2237-2242, 1991
8. Gimeno RE, Dembski M, Weng X, Deng N, Shyjan AW, Gimeno CJ, Iris F, Ellis SJ, Woolf EA, Tartaglia LA: Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis. Diabetes 46:900-906, 1997
9. Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levi-Meyrueis C, Bouillaud F, Seldin MF, Surwit RS, Ricquier D, Warden CH: Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet 15:269-273, 1997
10. Boss O, Samec S, Paoloni-Giacobino A, Rossier C, Dulloo A, Seydoux J, Muzzin P, Giacobino J-P: Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett 408:39-42, 1997
11. Vidal-Puig A, Solanes G, Grujic D, Flier JS, Lowell BB: UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem Biophys Res Commun 235:79-82, 1997
12. Gong D-W, He Y, Karas M, Reitman M: Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, β3-adrenergic agonists, and leptin. J Biol Chem 272:24129-24132, 1997
13. Bouchard C, Pérusse L, Chagnon YC, Warden G, Ricquier D: Linkage between markers in the vicinity of the uncoupling protein 2 gene and resting metabolic rate in humans. Hum Mol Genet 6:1887-1889, 1997
14. Solanes G, Vidal-Puig A, Grujic D, Flier JS, Lowell BB: The human uncoupling protein-3 gene: genomic structure, chromosomal localization, and genetic basis for short and long form transcripts. J Biol Chem 272:25433-25436, 1997
15. WHO Study Group: Prevention of Diabetes Mellitus. Geneva, World Health Organization, 1994 (WHO Tech. Rep. Ser. 727)
16. Tataranni PA, Ravussin E: Use of dual X-ray absorptiometry in obese individuals. Am. J Clin Nutr 55:730-734, 1995
17. Walder K, Norman RA, Hanson RL, Schrauwen P, Neverova M, Jenkinson CP, Easlick J, Warden CH, Pecqueur C, Raimbault S, Ricquier D, Harper M, Silver K, Shuldiner AR, Solanes G, Lowell BB, Chung WK, Leibel RL, Pratley R, Ravussin E: Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima Indians. Hum Mol Genet 7:1431-1435, 1998
18. Barbe P, Millet L, Larrouy D, Galitzky J, Berlan M, Louvet J-P, Langin D: Uncoupling protein-2 messenger ribonucleic acid expression during very-low-calorie diet in obese premenopausal women. J Clin Endocrinol Metab 88:2450-2453, 1998
19. Millet L, Vidal H, Andreelli F, Larrouy D, Riou J-P, Ricquier D, Laville M, Langin D: Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans. J Clin Invest 100:2665-2670, 1997
20. Bouillaud F, Arechage I, Petit PX, Raimbault S, Levi-Meyrueis C, Casteilla L, Laurent M, Rial E, Ricquier D: A sequence related to a DNA recognition element is essential for the inhibition by nucleotides of proton transport through the mitochondrial uncoupling protein. EMBO J 13:1990-1997, 1994
21. Pratley RE, Thompson DB, Prochazka M, Baier L, Mott D, Ravussin E, Sakul H, Ehm MG, Burns DK, Foroud T, Garvey WT, Hanson RL, Knowler WC, Bennett PH, Bogardus C: An autosomal genomic scan for loci linked to pre-diabetic phenotypes in Pima Indians. J Clin Invest 101:1757-1764, 1998
22. Weigle DS, Selfridge LE, Schwartz MW, Seeley RJ, Cummings DE, Havel PJ, Kuijper JL, BertrandelRio H: Elevated free fatty acids induce uncoupling protein 3 expression in muscle: a potential explanation for the effect of fasting. Diabetes 47:298-302, 1998