Resolving individual steps in the operation of ATP-dependent proteolytic molecular machines: From conformational changes to substrate translocation and processivity

Biochemistry

Volumn 47, Issue 12, 2008, Pages 3595-3605

  Licht, Stuart ^a   Lee, Irene ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEOLYTIC MOLECULAR MACHINES; SUBSTRATE TRANSLOCATION;

CONFORMATIONS; FREE ENERGY; MOLECULAR DYNAMICS; PROTEOLYSIS;

PROTEIN FOLDING;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DEPENDENT PROTEINASE; ENDOPEPTIDASE CLP; ENDOPEPTIDASE LA; FTSH ENZYME; UNCLASSIFIED DRUG;

BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW;

ATP-DEPENDENT PROTEASES; BINDING SITES; ENDOPEPTIDASE CLP; ESCHERICHIA COLI PROTEINS; KINETICS; MODELS, CHEMICAL; PROTEASE LA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, QUATERNARY;

EID: 41149142931     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800025g     Document Type: Review

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