Structural and Functional Characterization of the NHR1 Domain of the Drosophila Neuralized E3 Ligase in the Notch Signaling Pathway

Journal of Molecular Biology

Volumn 393, Issue 2, 2009, Pages 478-495

  He, Fahu ^a   Saito, Kohei ^a   Kobayashi, Naohiro ^a   Harada, Takushi ^a   Watanabe, Satoru ^a   Kigawa, Takanori ^a,b   Güntert, Peter ^a,c,d   Ohara, Osamu ^e,f   Tanaka, Akiko ^a   Unzai, Satoru ^g   Muto, Yutaka ^a   Yokoyama, Shigeyuki ^a,h  

^a RIKEN   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c RIKEN YOKOHAMA INSTITUTE   (Japan)

^d FRANKFURT INSTITUTE FOR ADVANCED STUDIES   (Germany)

^e KAZUSA DNA RESEARCH INSTITUTE   (Japan)

^f RIKEN Center for Integrative Medical Sciences   (Japan)

^g YOKOHAMA CITY UNIVERSITY   (Japan)

^h UNIVERSITY OF TOKYO   (Japan)

Author keywords

Neuralized (Neur); neuralized homology repeat (NHR) domain; NMR; Notch signaling pathway; solution structure

Indexed keywords

CARBON 13; NEUTRALIZED HOMOLOGY REPEAT 1 DOMAIN PROTEIN; NITROGEN 15; NOTCH RECEPTOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; UBIQUITIN PROTEIN LIGASE;

AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; CELL FREE SYSTEM; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME STRUCTURE; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; CLASSIFICATION; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

DROSOPHILA MELANOGASTER;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NOTCH; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 70349419517     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.08.020     Document Type: Article

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