메뉴 건너뛰기




Volumn 4, Issue 9, 2009, Pages

Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN SPT5; RNA POLYMERASE II; UNCLASSIFIED DRUG; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HISTONE; NONHISTONE PROTEIN; SPT5 TRANSCRIPTIONAL ELONGATION FACTOR; TRANSCRIPTION ELONGATION FACTOR;

EID: 70349149449     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006918     Document Type: Article
Times cited : (24)

References (56)
  • 1
    • 0842265974 scopus 로고    scopus 로고
    • Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors
    • Kadonaga JT (2004) Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors. Cell 116: 247-257.
    • (2004) Cell , vol.116 , pp. 247-257
    • Kadonaga, J.T.1
  • 3
    • 15744388341 scopus 로고    scopus 로고
    • A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation
    • Barboric M, Peterlin BM (2005) A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation. PLoS Biol 3: e76.
    • (2005) PLoS Biol , vol.3
    • Barboric, M.1    Peterlin, B.M.2
  • 4
    • 0022817308 scopus 로고
    • RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster cells
    • Gilmour DS, Lis JT (1986) RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster cells. Mol Cell Biol 6: 3984-3989.
    • (1986) Mol Cell Biol , vol.6 , pp. 3984-3989
    • Gilmour, D.S.1    Lis, J.T.2
  • 5
    • 0023513563 scopus 로고
    • Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product
    • Kao SY, Calman AF, Luciw PA, Peterlin BM (1987) Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product. Nature 330: 489-493.
    • (1987) Nature , vol.330 , pp. 489-493
    • Kao, S.Y.1    Calman, A.F.2    Luciw, P.A.3    Peterlin, B.M.4
  • 6
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA (2007) A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130: 77-88.
    • (2007) Cell , vol.130 , pp. 77-88
    • Guenther, M.G.1    Levine, S.S.2    Boyer, L.A.3    Jaenisch, R.4    Young, R.A.5
  • 7
    • 34547624303 scopus 로고    scopus 로고
    • Genomewide maps of chromatin state in pluripotent and lineage-committed cells
    • Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, et al. (2007) Genomewide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448: 553-560.
    • (2007) Nature , vol.448 , pp. 553-560
    • Mikkelsen, T.S.1    Ku, M.2    Jaffe, D.B.3    Issac, B.4    Lieberman, E.5
  • 9
    • 36549013619 scopus 로고    scopus 로고
    • RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo
    • Zeitlinger J, Stark A, Kellis M, Hong JW, Nechaev S, et al. (2007) RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo. Nat Genet 39: 1512-1516.
    • (2007) Nat Genet , vol.39 , pp. 1512-1516
    • Zeitlinger, J.1    Stark, A.2    Kellis, M.3    Hong, J.W.4    Nechaev, S.5
  • 10
    • 0032836135 scopus 로고    scopus 로고
    • Transcription elongation and human disease
    • Conaway JW, Conaway RC (1999) Transcription elongation and human disease. Annu Rev Biochem 68: 301-309.
    • (1999) Annu Rev Biochem , vol.68 , pp. 301-309
    • Conaway, J.W.1    Conaway, R.C.2
  • 11
    • 5444225805 scopus 로고    scopus 로고
    • Elongation by RNA polymerase II: The short and long of it
    • Sims RJ, Belotserkovskaya R, Reinberg D (2004) Elongation by RNA polymerase II: the short and long of it. Genes Dev 18: 2437-2468.
    • (2004) Genes Dev , vol.18 , pp. 2437-2468
    • Sims, R.J.1    Belotserkovskaya, R.2    Reinberg, D.3
  • 12
    • 14444275279 scopus 로고    scopus 로고
    • DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
    • Wada T, Takagi T, Yamaguchi Y, Ferdous A, Imai T, et al. (1998) DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes Dev 12: 343-356.
    • (1998) Genes Dev , vol.12 , pp. 343-356
    • Wada, T.1    Takagi, T.2    Yamaguchi, Y.3    Ferdous, A.4    Imai, T.5
  • 13
    • 0033515521 scopus 로고    scopus 로고
    • NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
    • Yamaguchi Y, Takagi T, Wada T, Yano K, Furuya A, et al. (1999) NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell 97: 41-51.
    • (1999) Cell , vol.97 , pp. 41-51
    • Yamaguchi, Y.1    Takagi, T.2    Wada, T.3    Yano, K.4    Furuya, A.5
  • 14
    • 0027523232 scopus 로고
    • Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae
    • Malone EA, Fassler JS, Winston F (1993) Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae. Mol Gen Genet 237: 449-459.
    • (1993) Mol Gen Genet , vol.237 , pp. 449-459
    • Malone, E.A.1    Fassler, J.S.2    Winston, F.3
  • 15
    • 0342748478 scopus 로고    scopus 로고
    • Domains in the SPT5 protein that modulate its transcriptional regulatory properties
    • Ivanov D, Kwak YT, Guo J, Gaynor RB (2000) Domains in the SPT5 protein that modulate its transcriptional regulatory properties. Mol Cell Biol 20: 2970-2983.
    • (2000) Mol Cell Biol , vol.20 , pp. 2970-2983
    • Ivanov, D.1    Kwak, Y.T.2    Guo, J.3    Gaynor, R.B.4
  • 16
    • 0035853736 scopus 로고    scopus 로고
    • Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase
    • Kim JB, Sharp PA (2001) Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase. J Biol Chem 276: 12317-12323.
    • (2001) J Biol Chem , vol.276 , pp. 12317-12323
    • Kim, J.B.1    Sharp, P.A.2
  • 17
    • 0035965126 scopus 로고    scopus 로고
    • The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9
    • Lavoie SB, Albert AL, Handa H, Vincent M, Bensaude O (2001) The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9. J Mol Biol 312: 675-685.
    • (2001) J Mol Biol , vol.312 , pp. 675-685
    • Lavoie, S.B.1    Albert, A.L.2    Handa, H.3    Vincent, M.4    Bensaude, O.5
  • 18
    • 0242321980 scopus 로고    scopus 로고
    • Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 protein kinase: Spt5 phosphorylation, autophosphorylation, and mutational analysis
    • Pei Y, Shuman S (2003) Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 protein kinase: Spt5 phosphorylation, autophosphorylation, and mutational analysis. J Biol Chem 278: 43346-43356.
    • (2003) J Biol Chem , vol.278 , pp. 43346-43356
    • Pei, Y.1    Shuman, S.2
  • 19
    • 30744449491 scopus 로고    scopus 로고
    • P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation
    • Yamada T, Yamaguchi Y, Inukai N, Okamoto S, Mura T, et al. (2006) P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation. Mol Cell 21: 227-237.
    • (2006) Mol Cell , vol.21 , pp. 227-237
    • Yamada, T.1    Yamaguchi, Y.2    Inukai, N.3    Okamoto, S.4    Mura, T.5
  • 20
    • 0032534814 scopus 로고    scopus 로고
    • Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro
    • Wada T, Takagi T, Yamaguchi Y, Watanabe D, Handa H (1998) Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro. EMBO J 17: 7395-7403.
    • (1998) EMBO J , vol.17 , pp. 7395-7403
    • Wada, T.1    Takagi, T.2    Yamaguchi, Y.3    Watanabe, D.4    Handa, H.5
  • 21
    • 33746403681 scopus 로고    scopus 로고
    • Controlling the elongation phase of transcription with P-TEFb
    • Peterlin BM, Price DH (2006) Controlling the elongation phase of transcription with P-TEFb. Mol Cell 23: 297-305.
    • (2006) Mol Cell , vol.23 , pp. 297-305
    • Peterlin, B.M.1    Price, D.H.2
  • 22
    • 0025869163 scopus 로고
    • SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae encodes an acidic nuclear protein with a carboxy-terminal repeat
    • Swanson MS, malone EA, Winston F (1991) SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae encodes an acidic nuclear protein with a carboxy-terminal repeat. Mol Cell Biol 11: 3009-3019.
    • (1991) Mol Cell Biol , vol.11 , pp. 3009-3019
    • Swanson, M.S.1    malone, E.A.2    Winston, F.3
  • 23
    • 0037102566 scopus 로고    scopus 로고
    • CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo
    • Shim EY, Walker AK, Shi Y, Blackwell TK (2002) CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo. Genes Dev 16: 2135-2146.
    • (2002) Genes Dev , vol.16 , pp. 2135-2146
    • Shim, E.Y.1    Walker, A.K.2    Shi, Y.3    Blackwell, T.K.4
  • 24
    • 4544293017 scopus 로고    scopus 로고
    • Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila
    • Jennings BH, Shah S, Yamaguchi Y, Seki M, Phillips RG, et al. (2004) Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila. Curr Biol 14: 1680-1684.
    • (2004) Curr Biol , vol.14 , pp. 1680-1684
    • Jennings, B.H.1    Shah, S.2    Yamaguchi, Y.3    Seki, M.4    Phillips, R.G.5
  • 25
    • 0034676431 scopus 로고    scopus 로고
    • A regulator of transcriptional elongation, which is required for vertebrate neuronal development
    • Guo S, Yamaguchi Y, Schilbach S, Wada T, Goddard A, et al. (2000) A regulator of transcriptional elongation, which is required for vertebrate neuronal development. Nature 408: 366-369.
    • (2000) Nature , vol.408 , pp. 366-369
    • Guo, S.1    Yamaguchi, Y.2    Schilbach, S.3    Wada, T.4    Goddard, A.5
  • 26
    • 0036336890 scopus 로고    scopus 로고
    • The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo
    • Keegan BR, Feldman JL, Lee DH, Koos DS, Ho RK, et al. (2002) The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo. Development 129: 1623-1632.
    • (2002) Development , vol.129 , pp. 1623-1632
    • Keegan, B.R.1    Feldman, J.L.2    Lee, D.H.3    Koos, D.S.4    Ho, R.K.5
  • 27
    • 27444435588 scopus 로고    scopus 로고
    • Zebrafish foggy/spt 5 is required for migration of facial branchiomotor neurons but not for their survival
    • Cooper KL, Armstrong J, Moens CB (2005) Zebrafish foggy/spt 5 is required for migration of facial branchiomotor neurons but not for their survival. Dev Dyn 234: 651-658.
    • (2005) Dev Dyn , vol.234 , pp. 651-658
    • Cooper, K.L.1    Armstrong, J.2    Moens, C.B.3
  • 28
    • 0033566042 scopus 로고    scopus 로고
    • Transcription elongation factor hSPT5 stimulates mRNA capping
    • Wen Y, Shatkin AJ (1999) Transcription elongation factor hSPT5 stimulates mRNA capping. Genes Dev 13: 1774-1779.
    • (1999) Genes Dev , vol.13 , pp. 1774-1779
    • Wen, Y.1    Shatkin, A.J.2
  • 29
    • 0037205456 scopus 로고    scopus 로고
    • Interaction between fission yeast mRNA capping enzymes and elongation factor Spt5
    • Pei Y, Shuman S (2002) Interaction between fission yeast mRNA capping enzymes and elongation factor Spt5. J Biol Chem 277: 19639-19648.
    • (2002) J Biol Chem , vol.277 , pp. 19639-19648
    • Pei, Y.1    Shuman, S.2
  • 30
    • 0037313160 scopus 로고    scopus 로고
    • Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins
    • Lindstrom DL, Squazzo SL, Muster N, Burckin TA, Wachter KC, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23: 1368-1378.
    • (2003) Mol Cell Biol , vol.23 , pp. 1368-1378
    • Lindstrom, D.L.1    Squazzo, S.L.2    Muster, N.3    Burckin, T.A.4    Wachter, K.C.5
  • 31
    • 21844435714 scopus 로고    scopus 로고
    • Npl3 is an antagonist of mRNA 3′ end formation by RNA polymerase II
    • Bucheli ME, Buratowski S (2005) Npl3 is an antagonist of mRNA 3′ end formation by RNA polymerase II. EMBO J 24: 2150-2160.
    • (2005) EMBO J , vol.24 , pp. 2150-2160
    • Bucheli, M.E.1    Buratowski, S.2
  • 32
    • 0142059889 scopus 로고    scopus 로고
    • In vivo evidence that defects in the transcriptional elongation factors RPB2, TFIIS, and SPT5 enhance upstream poly(A) site utilization
    • Cui Y, Denis CL (2003) In vivo evidence that defects in the transcriptional elongation factors RPB2, TFIIS, and SPT5 enhance upstream poly(A) site utilization. Mol Cell Biol 23: 7887-7901.
    • (2003) Mol Cell Biol , vol.23 , pp. 7887-7901
    • Cui, Y.1    Denis, C.L.2
  • 33
    • 20144379765 scopus 로고    scopus 로고
    • Exploring functional relationships between components of the gene expression machinery
    • Burckin T, Nagel R, Mandel-Gutfreund Y, Shiue L, Clark TA, et al. (2005) Exploring functional relationships between components of the gene expression machinery. Nat Struct Mol Biol 12: 175-182.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 175-182
    • Burckin, T.1    Nagel, R.2    Mandel-Gutfreund, Y.3    Shiue, L.4    Clark, T.A.5
  • 34
    • 0034667949 scopus 로고    scopus 로고
    • High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: Roles in promoter proximal pausing and transcription elongation
    • Andrulis ED, Guzman E, Doring P, Werner J, Lis JT (2000) High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation. Genes Dev 14: 2635-2649.
    • (2000) Genes Dev , vol.14 , pp. 2635-2649
    • Andrulis, E.D.1    Guzman, E.2    Doring, P.3    Werner, J.4    Lis, J.T.5
  • 35
    • 0034667805 scopus 로고    scopus 로고
    • Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster
    • Kaplan CD, Morris JR, Wu C, Winston F (2000) Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster. Genes Dev 14: 2623-2634.
    • (2000) Genes Dev , vol.14 , pp. 2623-2634
    • Kaplan, C.D.1    Morris, J.R.2    Wu, C.3    Winston, F.4
  • 37
    • 0033583290 scopus 로고    scopus 로고
    • Structure and function of the human transcription elongation factor DSIF
    • Yamaguchi Y, Wada T, Watanabe D, Takagi T, Hasegawa J, et al. (1999) Structure and function of the human transcription elongation factor DSIF. J Biol Chem 274: 8085-8092.
    • (1999) J Biol Chem , vol.274 , pp. 8085-8092
    • Yamaguchi, Y.1    Wada, T.2    Watanabe, D.3    Takagi, T.4    Hasegawa, J.5
  • 38
    • 0742270279 scopus 로고    scopus 로고
    • Heat shock gene expression and function during zebrafish embryogenesis
    • Krone PH, Evans TG, Blechinger SR (2003) Heat shock gene expression and function during zebrafish embryogenesis. Semin Cell Dev Biol 14: 267-274.
    • (2003) Semin Cell Dev Biol , vol.14 , pp. 267-274
    • Krone, P.H.1    Evans, T.G.2    Blechinger, S.R.3
  • 39
    • 0034121384 scopus 로고    scopus 로고
    • Laser-induced gene expression in specific cells of transgneic zebrafish
    • Halloran MC, Sato-Maeda M, Warren JT, Su F, Lele Z, et al. (2000) Laser-induced gene expression in specific cells of transgneic zebrafish. Development 127: 1953-1960.
    • (2000) Development , vol.127 , pp. 1953-1960
    • Halloran, M.C.1    Sato-Maeda, M.2    Warren, J.T.3    Su, F.4    Lele, Z.5
  • 40
    • 0032571254 scopus 로고    scopus 로고
    • Role of the human homolog of the yeast transcription factor SPT5 in HIV-1 Tat-activation
    • Wu-Baer F, Lane WS, Gaynor RB (1998) Role of the human homolog of the yeast transcription factor SPT5 in HIV-1 Tat-activation. J Mol Biol 277: 179-197.
    • (1998) J Mol Biol , vol.277 , pp. 179-197
    • Wu-Baer, F.1    Lane, W.S.2    Gaynor, R.B.3
  • 41
    • 0346095303 scopus 로고    scopus 로고
    • Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element
    • Fujinaga K, Irwin D, Huang Y, Taube R, Kurosu T, et al. (2004) Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element. Mol Cell Biol 24: 787-795.
    • (2004) Mol Cell Biol , vol.24 , pp. 787-795
    • Fujinaga, K.1    Irwin, D.2    Huang, Y.3    Taube, R.4    Kurosu, T.5
  • 42
    • 0036275982 scopus 로고    scopus 로고
    • Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation
    • Kim YK, Bourgeois CF, Isel C, Churcher MJ, Karn J (2002) Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation. Mol Cell Biol 22: 4622-4637.
    • (2002) Mol Cell Biol , vol.22 , pp. 4622-4637
    • Kim, Y.K.1    Bourgeois, C.F.2    Isel, C.3    Churcher, M.J.4    Karn, J.5
  • 43
    • 18144372773 scopus 로고    scopus 로고
    • Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5
    • Ping YH, Chu CY, Cao H, Jacque JM, Stevenson M, et al. (2004) Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5. Retrovirology 1: 46.
    • (2004) Retrovirology , vol.1 , pp. 46
    • Ping, Y.H.1    Chu, C.Y.2    Cao, H.3    Jacque, J.M.4    Stevenson, M.5
  • 44
    • 0026440184 scopus 로고
    • Promoter melting and TFIID complexes on Drosophila genes in vivo
    • Giardina C, Pérez-Riba M, Lis JT (1992) Promoter melting and TFIID complexes on Drosophila genes in vivo. Genes Dev 6: 2190-2200.
    • (1992) Genes Dev , vol.6 , pp. 2190-2200
    • Giardina, C.1    Pérez-Riba, M.2    Lis, J.T.3
  • 45
    • 2642570305 scopus 로고    scopus 로고
    • The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
    • Schubeler D, MacAlpine DM, Scalzo D, Wirbelauer C, Kooperberg C, et al. (2004) The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. Genes Dev 18: 1263-1271.
    • (2004) Genes Dev , vol.18 , pp. 1263-1271
    • Schubeler, D.1    MacAlpine, D.M.2    Scalzo, D.3    Wirbelauer, C.4    Kooperberg, C.5
  • 46
    • 0037609009 scopus 로고    scopus 로고
    • NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila
    • Wu CH, Yamaguchi Y, Benjamin LR, Horvat-Gordon M, Washinsky J, et al. (2003) NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila. Genes Dev 17: 1402-1414.
    • (2003) Genes Dev , vol.17 , pp. 1402-1414
    • Wu, C.H.1    Yamaguchi, Y.2    Benjamin, L.R.3    Horvat-Gordon, M.4    Washinsky, J.5
  • 47
    • 0035834647 scopus 로고    scopus 로고
    • A highly purified RNA polymerase II elongation control system
    • Renner DB, Yamaguchi Y, Wada T, Handa H, Price DH (2001) A highly purified RNA polymerase II elongation control system. J Biol Chem 276: 42601-42609.
    • (2001) J Biol Chem , vol.276 , pp. 42601-42609
    • Renner, D.B.1    Yamaguchi, Y.2    Wada, T.3    Handa, H.4    Price, D.H.5
  • 48
    • 27244444725 scopus 로고    scopus 로고
    • A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS
    • Palangat M, Renner DB, Price DH, Landick R (2005) A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS. Proc Natl Acad Sci 102: 15036-15041.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 15036-15041
    • Palangat, M.1    Renner, D.B.2    Price, D.H.3    Landick, R.4
  • 49
    • 34547563511 scopus 로고    scopus 로고
    • Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation
    • Cheng B, Price DH (2007) Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation. J Biol Chem 282: 21901-21912.
    • (2007) J Biol Chem , vol.282 , pp. 21901-21912
    • Cheng, B.1    Price, D.H.2
  • 50
    • 47549090254 scopus 로고    scopus 로고
    • NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly
    • Gilchrist DA, Nechaev S, Lee C, Ghosh SK, Collins JB, et al. (2008) NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly. Genes Dev 22: 1921-1933.
    • (2008) Genes Dev , vol.22 , pp. 1921-1933
    • Gilchrist, D.A.1    Nechaev, S.2    Lee, C.3    Ghosh, S.K.4    Collins, J.B.5
  • 51
    • 43249086572 scopus 로고    scopus 로고
    • NELF and GAGA factor are linked to promoter-proximal pausing at many genes in Drosophila
    • Lee C, Li X, Hechmer A, Eisen M, Biggin MD, et al. (2008) NELF and GAGA factor are linked to promoter-proximal pausing at many genes in Drosophila. Mol Cell Biol 28: 3290-3300.
    • (2008) Mol Cell Biol , vol.28 , pp. 3290-3300
    • Lee, C.1    Li, X.2    Hechmer, A.3    Eisen, M.4    Biggin, M.D.5
  • 54
    • 0033231292 scopus 로고    scopus 로고
    • Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein Soulless/Phox2a
    • Guo S, Brush J, Teraoka H, Goddard A, Wilson SW, et al. (1999) Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein Soulless/Phox2a. Neuron 24: 555-566.
    • (1999) Neuron , vol.24 , pp. 555-566
    • Guo, S.1    Brush, J.2    Teraoka, H.3    Goddard, A.4    Wilson, S.W.5
  • 55
    • 37549060329 scopus 로고    scopus 로고
    • AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells
    • Oven I, Brdicková N, Kohoutek J, Vaupotic T, Narat M, et al. (2007) AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells. Mol Cell Biol 27: 8815-8823.
    • (2007) Mol Cell Biol , vol.27 , pp. 8815-8823
    • Oven, I.1    Brdicková, N.2    Kohoutek, J.3    Vaupotic, T.4    Narat, M.5
  • 56
    • 30444431914 scopus 로고    scopus 로고
    • NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
    • Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, et al. (2006) NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J 25: 139-149.
    • (2006) EMBO J , vol.25 , pp. 139-149
    • Williams, S.A.1    Chen, L.F.2    Kwon, H.3    Ruiz-Jarabo, C.M.4    Verdin, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.