메뉴 건너뛰기




Volumn 8, Issue 10, 2009, Pages 1179-1189

TREX1 acts in degrading damaged DNA from drug-treated tumor cells

Author keywords

Autoimmunity; Camptothecin; DNA degradation; Dying cells; TREX1

Indexed keywords

ARSENIC TRIOXIDE; CAMPTOTHECIN; CISPLATIN; CYTARABINE; DOXORUBICIN; ETOPOSIDE; EXONUCLEASE; GEMCITABINE; HYDROGEN PEROXIDE; OXALIPLATIN; PROTEIN TREX1; TROXACITABINE; UNCLASSIFIED DRUG;

EID: 70149107812     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2009.06.006     Document Type: Article
Times cited : (29)

References (56)
  • 1
    • 0014690918 scopus 로고
    • Properties of deoxyribonuclease 3 from mammalian tissues
    • Lindahl T., Gally J.A., and Edelman G.M. Properties of deoxyribonuclease 3 from mammalian tissues. J. Biol. Chem. 244 (1969) 5014-5019
    • (1969) J. Biol. Chem. , vol.244 , pp. 5014-5019
    • Lindahl, T.1    Gally, J.A.2    Edelman, G.M.3
  • 2
    • 0037786682 scopus 로고    scopus 로고
    • A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein
    • Hoss M., Robins P., Naven T.J., Pappin D.J., Sgouros J., and Lindahl T. A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein. EMBO J. 18 (1999) 3868-3875
    • (1999) EMBO J. , vol.18 , pp. 3868-3875
    • Hoss, M.1    Robins, P.2    Naven, T.J.3    Pappin, D.J.4    Sgouros, J.5    Lindahl, T.6
  • 3
    • 0033538461 scopus 로고    scopus 로고
    • Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3′ → 5′ exonucleases
    • Mazur D.J., and Perrino F.W. Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3′ → 5′ exonucleases. J. Biol. Chem. 274 (1999) 19655-19660
    • (1999) J. Biol. Chem. , vol.274 , pp. 19655-19660
    • Mazur, D.J.1    Perrino, F.W.2
  • 4
    • 0035907239 scopus 로고    scopus 로고
    • Excision of 3′ termini by the Trex1 and TREX2 3′ → 5′ exonucleases, characterization of the recombinant proteins
    • Mazur D.J., and Perrino F.W. Excision of 3′ termini by the Trex1 and TREX2 3′ → 5′ exonucleases, characterization of the recombinant proteins. J. Biol. Chem. 276 (2001) 17022-17029
    • (2001) J. Biol. Chem. , vol.276 , pp. 17022-17029
    • Mazur, D.J.1    Perrino, F.W.2
  • 5
    • 0028178394 scopus 로고
    • Identification of a 3′ → 5′-exonuclease that removes cytosine arabinoside monophosphate from 3′ termini of DNA
    • Perrino F.W., Miller H., and EaleyF K.A. Identification of a 3′ → 5′-exonuclease that removes cytosine arabinoside monophosphate from 3′ termini of DNA. J. Biol. Chem. 269 (1994) 16357-16363
    • (1994) J. Biol. Chem. , vol.269 , pp. 16357-16363
    • Perrino, F.W.1    Miller, H.2    EaleyF, K.A.3
  • 6
    • 34249848019 scopus 로고    scopus 로고
    • The crystal structure of TREX1 explains the 3′ nucleotide specificity and reveals a polyproline II helix for protein partnering
    • de Silva U., Choudhury S., Bailey S.L., Harvey S., Perrino F.W., and Hollis T. The crystal structure of TREX1 explains the 3′ nucleotide specificity and reveals a polyproline II helix for protein partnering. J. Biol. Chem. 282 (2007) 10537-10543
    • (2007) J. Biol. Chem. , vol.282 , pp. 10537-10543
    • de Silva, U.1    Choudhury, S.2    Bailey, S.L.3    Harvey, S.4    Perrino, F.W.5    Hollis, T.6
  • 7
    • 17644407757 scopus 로고    scopus 로고
    • The human TREX2 3′ → 5′-exonuclease structure suggests a mechanism for efficient nonprocessive DNA catalysis
    • Perrino F.W., Harvey S., McMillin S., and Hollis T. The human TREX2 3′ → 5′-exonuclease structure suggests a mechanism for efficient nonprocessive DNA catalysis. J. Biol. Chem. 280 (2005) 15212-15218
    • (2005) J. Biol. Chem. , vol.280 , pp. 15212-15218
    • Perrino, F.W.1    Harvey, S.2    McMillin, S.3    Hollis, T.4
  • 9
    • 0009448216 scopus 로고    scopus 로고
    • The TREX2 3′ → 5′ exonuclease physically interacts with DNA polymerase delta and increases its accuracy
    • Shevelev I.V., Ramadan K., and Hubscher U. The TREX2 3′ → 5′ exonuclease physically interacts with DNA polymerase delta and increases its accuracy. Sci. World J. 2 (2002) 275-281
    • (2002) Sci. World J. , vol.2 , pp. 275-281
    • Shevelev, I.V.1    Ramadan, K.2    Hubscher, U.3
  • 13
    • 48549085675 scopus 로고    scopus 로고
    • Aicardi-Goutieres syndrome (AGS)
    • Stephenson J.B. Aicardi-Goutieres syndrome (AGS). Eur. J. Paediatr. Neurol. 12 (2008) 355-358
    • (2008) Eur. J. Paediatr. Neurol. , vol.12 , pp. 355-358
    • Stephenson, J.B.1
  • 20
    • 57649134251 scopus 로고    scopus 로고
    • The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease
    • Lehtinen D.A., Harvey S., Mulcahy M.J., Hollis T., and Perrino F.W. The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease. J. Biol. Chem. 283 (2008) 31649-31656
    • (2008) J. Biol. Chem. , vol.283 , pp. 31649-31656
    • Lehtinen, D.A.1    Harvey, S.2    Mulcahy, M.J.3    Hollis, T.4    Perrino, F.W.5
  • 21
    • 36248988008 scopus 로고    scopus 로고
    • Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease
    • Yang Y.G., Lindahl T., and Barnes D.E. Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease. Cell 131 (2007) 873-886
    • (2007) Cell , vol.131 , pp. 873-886
    • Yang, Y.G.1    Lindahl, T.2    Barnes, D.E.3
  • 22
    • 36248943050 scopus 로고    scopus 로고
    • DNA mismanagement leads to immune system oversight
    • Coscoy L., and Raulet D.H. DNA mismanagement leads to immune system oversight. Cell 131 (2007) 836-838
    • (2007) Cell , vol.131 , pp. 836-838
    • Coscoy, L.1    Raulet, D.H.2
  • 23
    • 43849107357 scopus 로고    scopus 로고
    • Do all of the neurologic diseases in patients with DNA repair gene mutations result from the accumulation of DNA damage?
    • Brooks P.J., Cheng T.F., and Cooper L. Do all of the neurologic diseases in patients with DNA repair gene mutations result from the accumulation of DNA damage?. DNA Rep. (Amst.) 7 (2008) 834-848
    • (2008) DNA Rep. (Amst.) , vol.7 , pp. 834-848
    • Brooks, P.J.1    Cheng, T.F.2    Cooper, L.3
  • 24
    • 43849093697 scopus 로고    scopus 로고
    • TREX1 DNA exonuclease deficiency, accumulation of single stranded DNA and complex human genetic disorders
    • O'Driscoll M. TREX1 DNA exonuclease deficiency, accumulation of single stranded DNA and complex human genetic disorders. DNA Rep. (Amst.) 7 (2008) 997-1003
    • (2008) DNA Rep. (Amst.) , vol.7 , pp. 997-1003
    • O'Driscoll, M.1
  • 25
    • 49549100511 scopus 로고    scopus 로고
    • Trex1 prevents cell-intrinsic initiation of autoimmunity
    • Stetson D.B., Ko J.S., Heidmann T., and Medzhitov R. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134 (2008) 587-598
    • (2008) Cell , vol.134 , pp. 587-598
    • Stetson, D.B.1    Ko, J.S.2    Heidmann, T.3    Medzhitov, R.4
  • 26
    • 33745501366 scopus 로고    scopus 로고
    • The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death
    • Chowdhury D., Beresford P.J., Zhu P., Zhang D., Sung J.S., Demple B., Perrino F.W., and Lieberman J. The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death. Mol. Cell 23 (2006) 133-142
    • (2006) Mol. Cell , vol.23 , pp. 133-142
    • Chowdhury, D.1    Beresford, P.J.2    Zhu, P.3    Zhang, D.4    Sung, J.S.5    Demple, B.6    Perrino, F.W.7    Lieberman, J.8
  • 27
    • 42949098879 scopus 로고    scopus 로고
    • Death by a thousand cuts: granzyme pathways of programmed cell death
    • Chowdhury D., and Lieberman J. Death by a thousand cuts: granzyme pathways of programmed cell death. Annu. Rev. Immunol. 26 (2008) 389-420
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 389-420
    • Chowdhury, D.1    Lieberman, J.2
  • 28
    • 13444261490 scopus 로고    scopus 로고
    • Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake
    • Lam W., Chen C., Ruan S., Leung C.H., and Cheng Y.C. Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake. Mol. Pharmacol. 67 (2005) 408-416
    • (2005) Mol. Pharmacol. , vol.67 , pp. 408-416
    • Lam, W.1    Chen, C.2    Ruan, S.3    Leung, C.H.4    Cheng, Y.C.5
  • 29
    • 0038043250 scopus 로고    scopus 로고
    • The exonuclease activity of human apurinic/apyrimidinic endonuclease (APE1). Biochemical properties and inhibition by the natural dinucleotide Gp4G
    • Chou K.M., and Cheng Y.C. The exonuclease activity of human apurinic/apyrimidinic endonuclease (APE1). Biochemical properties and inhibition by the natural dinucleotide Gp4G. J. Biol. Chem. 278 (2003) 18289-18296
    • (2003) J. Biol. Chem. , vol.278 , pp. 18289-18296
    • Chou, K.M.1    Cheng, Y.C.2
  • 30
    • 0023244718 scopus 로고
    • Induction of virus enzymes by phorbol esters and n-butyrate in Epstein-Barr virus genome-carrying Raji cells
    • Nutter L.M., Grill S.P., Li J.S., Tan R.S., and Cheng Y.C. Induction of virus enzymes by phorbol esters and n-butyrate in Epstein-Barr virus genome-carrying Raji cells. Cancer Res. 47 (1987) 4407-4412
    • (1987) Cancer Res. , vol.47 , pp. 4407-4412
    • Nutter, L.M.1    Grill, S.P.2    Li, J.S.3    Tan, R.S.4    Cheng, Y.C.5
  • 31
    • 1642475128 scopus 로고    scopus 로고
    • Novel mode of action of tylophorine analogs as antitumor compounds
    • Gao W., Lam W., Zhong S., Kaczmarek C., Baker D.C., and Cheng Y.C. Novel mode of action of tylophorine analogs as antitumor compounds. Cancer Res. 64 (2004) 678-688
    • (2004) Cancer Res. , vol.64 , pp. 678-688
    • Gao, W.1    Lam, W.2    Zhong, S.3    Kaczmarek, C.4    Baker, D.C.5    Cheng, Y.C.6
  • 32
    • 0022403590 scopus 로고
    • The sources of thymidine nucleotides for virus DNA synthesis in herpes simplex virus type 2-infected cells
    • Nutter L.M., Grill S.P., and Cheng Y.C. The sources of thymidine nucleotides for virus DNA synthesis in herpes simplex virus type 2-infected cells. J. Biol. Chem. 260 (1985) 13272-13275
    • (1985) J. Biol. Chem. , vol.260 , pp. 13272-13275
    • Nutter, L.M.1    Grill, S.P.2    Cheng, Y.C.3
  • 33
    • 0035805548 scopus 로고    scopus 로고
    • Structure and expression of the TREX1 and TREX2 3′ → 5′ exonuclease genes
    • Mazur D.J., and Perrino F.W. Structure and expression of the TREX1 and TREX2 3′ → 5′ exonuclease genes. J. Biol. Chem. 276 (2001) 14718-14727
    • (2001) J. Biol. Chem. , vol.276 , pp. 14718-14727
    • Mazur, D.J.1    Perrino, F.W.2
  • 34
    • 0029072716 scopus 로고
    • Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity
    • Beidler D.R., and Cheng Y.C. Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity. Mol. Pharmacol. 47 (1995) 907-914
    • (1995) Mol. Pharmacol. , vol.47 , pp. 907-914
    • Beidler, D.R.1    Cheng, Y.C.2
  • 35
    • 0033226985 scopus 로고    scopus 로고
    • Differences in induction of p53, p21WAF1 and apoptosis in relation to cell cycle phase of MCF-7 cells treated with camptothecin
    • Deptala A., Li X., Bedner E., Cheng W., Traganos F., and Darzynkiewicz Z. Differences in induction of p53, p21WAF1 and apoptosis in relation to cell cycle phase of MCF-7 cells treated with camptothecin. Int. J. Oncol. 15 (1999) 861-871
    • (1999) Int. J. Oncol. , vol.15 , pp. 861-871
    • Deptala, A.1    Li, X.2    Bedner, E.3    Cheng, W.4    Traganos, F.5    Darzynkiewicz, Z.6
  • 37
    • 0032500543 scopus 로고    scopus 로고
    • Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs
    • Simizu S., Takada M., Umezawa K., and Imoto M. Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs. J. Biol. Chem. 273 (1998) 26900-26907
    • (1998) J. Biol. Chem. , vol.273 , pp. 26900-26907
    • Simizu, S.1    Takada, M.2    Umezawa, K.3    Imoto, M.4
  • 38
    • 14544288305 scopus 로고    scopus 로고
    • Co-localization of poly(ADPR)polymerase 1 (PARP-1) poly(ADPR)polymerase 2 (PARP-2) and related proteins in rat testis nuclear matrix defined by chemical cross-linking
    • Tramontano F., Di Meglio S., and Quesada P. Co-localization of poly(ADPR)polymerase 1 (PARP-1) poly(ADPR)polymerase 2 (PARP-2) and related proteins in rat testis nuclear matrix defined by chemical cross-linking. J. Cell. Biochem. 94 (2005) 58-66
    • (2005) J. Cell. Biochem. , vol.94 , pp. 58-66
    • Tramontano, F.1    Di Meglio, S.2    Quesada, P.3
  • 39
    • 84934442764 scopus 로고    scopus 로고
    • Nucleolar remodeling in nuclear transfer embryos
    • Laurincik J., and Maddox-Hyttel P. Nucleolar remodeling in nuclear transfer embryos. Adv. Exp. Med. Biol. 591 (2007) 84-92
    • (2007) Adv. Exp. Med. Biol. , vol.591 , pp. 84-92
    • Laurincik, J.1    Maddox-Hyttel, P.2
  • 44
    • 35148822715 scopus 로고    scopus 로고
    • Cisplatin depletes TREX2 and causes Robertsonian translocations as seen in TREX2 knockout cells
    • Chen M.J., Dumitrache L.C., Wangsa D., Ma S.M., Padilla-Nash H., Ried T., and Hasty P. Cisplatin depletes TREX2 and causes Robertsonian translocations as seen in TREX2 knockout cells. Cancer Res. 67 (2007) 9077-9083
    • (2007) Cancer Res. , vol.67 , pp. 9077-9083
    • Chen, M.J.1    Dumitrache, L.C.2    Wangsa, D.3    Ma, S.M.4    Padilla-Nash, H.5    Ried, T.6    Hasty, P.7
  • 45
    • 34347226273 scopus 로고    scopus 로고
    • ISG20, an actor of the innate immune response
    • Degols G., Eldin P., and Mechti N. ISG20, an actor of the innate immune response. Biochimie 89 (2007) 831-835
    • (2007) Biochimie , vol.89 , pp. 831-835
    • Degols, G.1    Eldin, P.2    Mechti, N.3
  • 46
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang Y.H., Hertzberg R., Hecht S., and Liu L.F. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem. 260 (1985) 14873-14878
    • (1985) J. Biol. Chem. , vol.260 , pp. 14873-14878
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 47
    • 0035029153 scopus 로고    scopus 로고
    • Tumor cell death induced by topoisomerase-targeting drugs
    • Li T.K., and Liu L.F. Tumor cell death induced by topoisomerase-targeting drugs. Annu. Rev. Pharmacol. Toxicol. 41 (2001) 53-77
    • (2001) Annu. Rev. Pharmacol. Toxicol. , vol.41 , pp. 53-77
    • Li, T.K.1    Liu, L.F.2
  • 49
    • 33947608268 scopus 로고    scopus 로고
    • Activation of nuclear factor kappa B by different agents: influence of culture conditions in a cell-based assay
    • Hellweg C.E., Arenz A., Bogner S., Schmitz C., and Baumstark-Khan C. Activation of nuclear factor kappa B by different agents: influence of culture conditions in a cell-based assay. Ann. N.Y. Acad. Sci. 1091 (2006) 191-204
    • (2006) Ann. N.Y. Acad. Sci. , vol.1091 , pp. 191-204
    • Hellweg, C.E.1    Arenz, A.2    Bogner, S.3    Schmitz, C.4    Baumstark-Khan, C.5
  • 50
    • 33645498154 scopus 로고    scopus 로고
    • En masse nascent transcription analysis to elucidate regulatory transcription factors
    • Fan J., Zhan M., Shen J., Martindale J.L., Yang X., Kawai T., and Gorospe M. En masse nascent transcription analysis to elucidate regulatory transcription factors. Nucleic Acids Res. 34 (2006) 1492-1500
    • (2006) Nucleic Acids Res. , vol.34 , pp. 1492-1500
    • Fan, J.1    Zhan, M.2    Shen, J.3    Martindale, J.L.4    Yang, X.5    Kawai, T.6    Gorospe, M.7
  • 51
    • 39349090624 scopus 로고    scopus 로고
    • Nucleic acid recognition receptors in autoimmunity
    • Krug A. Nucleic acid recognition receptors in autoimmunity. Handb. Exp. Pharmacol. (2008) 129-151
    • (2008) Handb. Exp. Pharmacol. , pp. 129-151
    • Krug, A.1
  • 52
    • 49549122469 scopus 로고    scopus 로고
    • Linking retroelements to autoimmunity
    • Bhoj V.G., and Chen Z.J. Linking retroelements to autoimmunity. Cell 134 (2008) 569-571
    • (2008) Cell , vol.134 , pp. 569-571
    • Bhoj, V.G.1    Chen, Z.J.2
  • 55
    • 36749027112 scopus 로고    scopus 로고
    • Apoptotic cell clearance and autoimmune disorder
    • Tanaka M., and Miyake Y. Apoptotic cell clearance and autoimmune disorder. Curr. Med. Chem. 14 (2007) 2892-2897
    • (2007) Curr. Med. Chem. , vol.14 , pp. 2892-2897
    • Tanaka, M.1    Miyake, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.