Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW domains

Journal of Biological Chemistry

Volumn 282, Issue 19, 2007, Pages 14547-14557

  Brucet, Marina ^a   Querol Audí, Jordi ^b   Serra, Maria ^a   Ramirez Espain, Ximena ^c   Bertlik, Kamila ^a   Ruiz, Lidia ^c   Lloberas, Jorge ^a   Macias, Maria J ^c   Fita, Ignacio ^b   Celada, Antonio ^a,d  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^d NONE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASMIC SUBCELLULAR COMPARTMENTS; DNA EXONUCLEASE; DNA SUBSTRATE; EXONUCLEASE REACTION;

BINDING SITES; CRYSTAL STRUCTURE; ENZYME ACTIVITY; NUCLEOTIDES; PLASMA (HUMAN); PROTEINS;

DNA SEQUENCES;

DNA; EXONUCLEASE; LEUCINE; PROLINE; TRANSCRIPTION FACTOR; TREX1 PROTEIN; UNCLASSIFIED DRUG; EXODEOXYRIBONUCLEASE; PHOSPHOPROTEIN; TREX1 PROTEIN, MOUSE;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFOCAL MICROSCOPY; CRYSTAL STRUCTURE; DNA SEQUENCE; ENZYME ACTIVITY; IMMUNOPRECIPITATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; ANIMAL; BINDING SITE; CELL FRACTIONATION; CELL NUCLEUS; CHEMISTRY; CYTOPLASM; DIMERIZATION; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

MAMMALIA; MURINAE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL NUCLEUS; CRYSTALLOGRAPHY, X-RAY; CYTOPLASM; DIMERIZATION; DNA; EXODEOXYRIBONUCLEASES; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROLINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SUBCELLULAR FRACTIONS;

EID: 34347265261     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700236200     Document Type: Article

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