Impaired clearance of dying cells in systemic lupus erythematosus

Autoimmunity Reviews

Volumn 4, Issue 4, 2005, Pages 189-194

  Gaipl, Udo S ^a   Voll, Reinhard E ^b   Sheriff, Ahmed ^a   Franz, Sandra ^a   Kalden, Joachim R ^a   Herrmann, Martin ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Apoptosis; Clearance; Macrophages; SLE; Stem cells

Indexed keywords

AUTOANTIBODY; CD34 ANTIGEN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4;

APOPTOSIS; AUTOIMMUNITY; CELL COUNT; CELL DEATH; COMPLEMENT ACTIVATION; DENDRITIC CELL; FIBROBLAST CULTURE; FOLLICULAR DENDRITIC CELL; GENE DELETION; GENE TARGETING; GERMINAL CENTER; HUMAN; LUNG ALVEOLUS MACROPHAGE; LYMPHOCYTE PROLIFERATION; MACROPHAGE ACTIVATION; MACROPHAGE MIGRATION; MOLECULAR RECOGNITION; OPSONIZATION; REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; APOPTOSIS; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MACROPHAGES; MICE; PHAGOCYTOSIS;

EID: 18944365579     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2004.10.007     Document Type: Review

References (35)

1. J.J. Cohen Apoptosis Immunol. Today 14 1993 126 130
2. R.E. Voll, M. Herrmann, E.A. Roth, C. Stach, J.R. Kalden, and I. Girkontaite Immunosuppressive effects of apoptotic cells Nature 390 1997 350 351
3. N.I. Walker, B.V. Harmon, G.C. Gobe, and J.F. Kerr Patterns of cell death Methods Achiev. Exp. Pathol. 13 1988 18 54
4. W. Lieberthal, and J.S. Levine Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury Am. J. Physiol. 271 1996 F477 F488
5. R.E. Ellis, D.M. Jacobson, and H.R. Horvitz Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans Genetics 129 1991 79 94
6. P. Rovere, F. Fazzini, M.G. Sabbadini, and A.A. Manfredi Apoptosis and systemic autoimmunity: the dendritic cell connection Eur. J. Histochem. 44 2000 229 236
7. M. Herrmann, R.E. Voll, and J.R. Kalden Etiopathogenesis of systemic lupus erythematosus Immunol. Today 21 2000 424 426
8. M. Botto, C. Dell'Agnola, A.E. Bygrave, E.M. Thompson, H.T. Cook, and F. Petry Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies Nat. Genet. 19 1998 56 59
9. M. Napirei, H. Karsunky, B. Zevnik, H. Stephan, H.G. Mannherz, and T. Moroy Features of systemic lupus erythematosus in Dnase1-deficient mice Nat. Genet. 25 2000 177 181
10. M. Boes, T. Schmidt, K. Linkemann, B.C. Beaudette, A. Marshak-Rothstein, and J. Chen Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM Proc. Natl. Acad. Sci. U. S. A. 97 2000 1184 1189
11. M.C. Bickerstaff, M. Botto, W.L. Hutchinson, J. Herbert, G.A. Tennent, and A. Bybee Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity Nat. Med. 5 1999 694 697
12. R.W. Vandivier, C.A. Ogden, V.A. Fadok, P.R. Hoffmann, K.K. Brown, and M. Botto Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex J. Immunol. 169 2002 3978 3986
13. H. Clark, N. Palaniyar, S. Hawgood, and K.B. Reid A recombinant fragment of human surfactant protein D reduces alveolar macrophage apoptosis and pro-inflammatory cytokines in mice developing pulmonary emphysema Ann. N.Y. Acad. Sci. 1010 2003 113 116
14. M.J. Walport Lupus, DNase and defective disposal of cellular debris [news; comment] Nat. Genet. 25 2000 135 136
15. R.S. Scott, E.J. McMahon, S.M. Pop, E.A. Reap, R. Caricchio, and P.L. Cohen Phagocytosis and clearance of apoptotic cells is mediated by MER Nature 411 2001 207 211
16. R. Hanayama, M. Tanaka, K. Miyasaka, K. Aozasa, M. Koike, and Y. Uchiyama Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice Science 304 2004 1147 1150
17. M.O. Li, M.R. Sarkisian, W.Z. Mehal, P. Rakic, and R.A. Flavell Phosphatidylserine receptor is required for clearance of apoptotic cells Science 302 2003 1560 1563
18. S.P. Hart, J.R. Smith, and I. Dransfield Phagocytosis of opsonized apoptotic cells: roles for 'old-fashioned' receptors for antibody and complement Clin. Exp. Immunol. 135 2004 181 185
19. A.I. Russell, D.S. Cunninghame Graham, C. Shepherd, C.A. Roberton, J. Whittaker, and J. Meeks Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus Hum. Mol. Genet. 13 2004 137 147
20. S. Chitrabamrung, R.L. Rubin, and E.M. Tan Serum deoxyribonuclease I and clinical activity in systemic lupus erythematosus Rheumatol. Int. 1 1981 55 60
21. M.J. Walport, K.A. Davies, and M. Botto C1q and systemic lupus erythematosus Immunobiology 199 1998 265 285
22. C. Mold, and C.A. Morris Complement activation by apoptotic endothelial cells following hypoxia/reoxygenation Immunology 102 2001 359 364
23. U.S. Gaipl, S. Kuenkele, R.E. Voll, T.D. Beyer, W. Kolowos, and P. Heyder Complement binding is an early feature of necrotic and a rather late event during apoptotic cell death Cell Death Differ. 8 2001 327 334
24. J.S. Navratil, L.C. Korb, and J.M. Ahearn Systemic lupus erythematosus and complement deficiency: clues to a novel role for the classical complement pathway in the maintenance of immune tolerance Immunopharmacology 42 1999 47 52
25. D. Mevorach, J.O. Mascarenhas, D. Gershov, and K.B. Elkon Complement-dependent clearance of apoptotic cells by human macrophages J. Exp. Med. 188 1998 2313 2320
26. P.R. Taylor, A. Carugati, V.A. Fadok, H.T. Cook, M. Andrews, and M.C. Carroll A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo J. Exp. Med. 192 2000 359 366
27. U.S. Gaipl, T.D. Beyer, P. Heyder, S. Kuenkele, A. Bottcher, and R.E. Voll Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin Arthritis Rheum. 50 2004 640 649
28. M. Napirei, S. Wulf, and H.G. Mannherz Chromatin breakdown during necrosis by serum Dnase1 and the plasminogen system Arthritis Rheum. 50 2004 1873 1883
29. M. Herrmann, R.E. Voll, O.M. Zoller, M. Hagenhofer, B.B. Ponner, and J.R. Kalden Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus Arthritis Rheum. 41 1998 1241 1250
30. A. Perniok, F. Wedekind, M. Herrmann, C. Specker, and M. Schneider High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus Lupus 7 1998 113 118
31. I. Baumann, W. Kolowos, R.E. Voll, B. Manger, U. Gaipl, and W.L. Neuhuber Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus Arthritis Rheum. 46 2002 191 201
32. C.A. Casiano, R.L. Ochs, and E.M. Tan Distinct cleavage products of nuclear proteins in apoptosis and necrosis revealed by autoantibody probes Cell Death Differ. 5 1998 183 190
33. L. Casciola-Rosen, F. Andrade, D. Ulanet, W.B. Wong, and A. Rosen Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity J. Exp. Med. 190 1999 815 826
34. K.D. Moudgil, E.E. Sercarz, and I.S. Grewal Modulation of the immunogenicity of antigenic determinants by their flanking residues Immunol. Today 19 1998 217 220
35. V.A. Fadok, D.L. Bratton, A. Konowal, P.W. Freed, J.Y. Westcott, and P.M. Henson Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF J. Clin. Invest. 101 1998 890 898