Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides: Peptide properties and plausible modes of action

Journal of Biological Chemistry

Volumn 281, Issue 3, 2006, Pages 1636-1643

  Rosenfeld, Yosef ^a   Papo, Niv ^a   Shai, Yechiel ^a,b  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b Department of Cancer Research ^*  (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITE; CYTOKINE; MACROPHAGES;

AMINO ACIDS; BIOCHEMISTRY; BONE; COMPOSITION; IMMUNOLOGY; MOLECULAR BIOLOGY; POLYMERIZATION; POLYPEPTIDES; PROTEINS;

TOXIC MATERIALS;

AMINO ACID; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; DEXTRO AMINO ACID; ENDOTOXIN; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; LIPOPOLYSACCHARIDE; MAGAININ 1; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; INTERLEUKIN 6; LIPOPOLYSACCHARIDE 6B, YERSINIA PESTIS; LIPOPOLYSACCHARIDE-6B, YERSINIA PESTIS; MESSENGER RNA; PEPTIDE; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DRUG INHIBITION; FLOW CYTOMETRY; FLUORESCENCE SPECTROSCOPY; HOST RESISTANCE; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SERODIAGNOSIS; BINDING SITE; CHEMISTRY; GENETICS; HUMAN; IMMUNOLOGY; MICROBIOLOGICAL EXAMINATION; MOLECULAR GENETICS; SIMIAN SARCOMA VIRUS;

ANIMALIA;

AMINO ACID SEQUENCE; BINDING SITES; ENDOTOXINS; HUMANS; IMMUNITY, NATURAL; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; PEPTIDES; RNA, MESSENGER; SARCOMA VIRUS, WOOLLY MONKEY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33644978944     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M504327200     Document Type: Article

References (44)

1. Raetz, C. R., and Whitfield, C. (2002) Annu. Rev. Biochem. 71, 635-700
2. Hopkin, D. A. (1978) Lancet 2, 1193-1194
3. Hancock, R. E., and Scott, M. G. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 8856-8861
4. Rietschel, E. T., Brade, H., Holst, O., Brade, L., Muller-Loennies, S., Mamat, U., Zahringer, U., Beckmann, F., Seydel, U., Brandenburg, K., Ulmer, A. J., Mattern, T., Heine, H., Schletter, J., Loppnow, H., Schonbeck, U., Flad, H. D., Hauschildt, S., Schade, U. F., Di Padova, F., Kusumoto, S., and Schumann, R. R. (1996) Curr. Top. Microbiol. Immunol. 216, 39-81
5. Zhang, F. X., Kirschning, C. J., Mancinelli, R., Xu, X. P., Jin, Y., Faure, E., Mantovani, A., Rothe, M., Muzio, M., and Arditi, M. (1999) J. Biol. Chem. 274, 7611-7614
6. Dobrovolskaia, M. A., and Vogel, S. N. (2002) Microbes Infect. 4, 903-914
7. Hardaway, R. M. (2000) Am. Surg. 66, 22-29
8. Cohen, J. (2002) Nature 420, 885-891
9. Wright, S. D., Ramos, R. A., Tobias, P. S., Ulevitch, R. J., and Mathison, J. C. (1990) Science 249, 1431-1433
10. Schumann, R. R., Leong, S. R., Flaggs, G. W., Gray, P. W., Wright, S. D., Mathison, J. C., Tobias, P. S., and Ulevitch, R. J. (1990) Science 249, 1429-1431
11. Tobias, P. S., and Ulevitch, R. J. (1993) Immunobiology 187, 227-232
12. Hailman, E., Lichenstein, H. S., Wurfel, M. M., Miller, D. S., Johnson, D. A., Kelley, M., Busse, L. A., Zukowski, M. M., and Wright, S. D. (1994) J. Exp. Med. 179, 269-277
13. Poltorak, A., He, X., Smirnova, I., Liu, M. Y., Van Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., Freudenberg, M., Ricciardi-Castagnoli, P., Layton, B., and Beutler, B. (1998) Science 282, 2085-2088
14. Woltmann, A., Hamann, L., Ulmer, A. J., Gerdes, J., Bruch, H. P., and Rietschel, E. T. (1998) Langenbecks Arch. Surg. 383, 2-10
15. Chow, J. C., Young, D. W., Golenbock, D. T., Christ, W. J., and Gusovsky, F. (1999) J. Biol. Chem. 274, 10689-10692
16. Jiang, Q., Akashi, S., Miyake, K., and Petty, H. R. (2000) J. Immunol. 165, 3541-3544
17. Schimke, J., Mathison, J., Morgiewicz, J., and Ulevitch, R. J. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13875-13880
18. Stover, A. G., Da Silva Correia, J., Evans, J. T., Cluff, C. W., Elliott, M. W., Jeffery, E. W., Johnson, D. A., Lacy, M. J., Baldridge, J. R., Probst, P., Ulevitch, R. J., Persing, D. H., and Hershberg, R. M. (2004) J. Biol. Chem. 279, 4440-4449
19. David, S. A. (2001) J. Mol. Recognit. 14, 370-387
20. Manocha, S., Feinstein, D., and Kumar, A. (2002) Expert Opin. Investig. Drugs 11, 1795-1812
21. Boman, H. G. (1995) Annu. Rev. Immunol. 13, 61-92
22. Zasloff, M. (2002) Nature 415, 389-395
23. Larrick, J. W., Hirata, M., Balint, R. F., Lee, J., Zhong, J., and Wright, S. C. (1995) Infect. Immun. 63, 1291-1297
24. Hirata, M., Zhong, J., Wright, S. C., and Larrick, J. W. (1995) Prog. Clin. Biol. Res. 392, 317-326
25. Gough, M., Hancock, R. E., and Kelly, N. M. (1996) Infect. Immun. 64, 4922-4927
26. Scott, M. G., Yan, H., and Hancock, R. E. (1999) Infect. Immun. 67, 2005-2009
27. Giacometti, A., Cirioni, O., Ghiselli, R., Mocchegiani, F., Del Prete, M. S., Viticchi, C., Kamysz, W., Lempicka, E., Saba, V., and Scalise, G. (2002) Antimicrob. Agents Chemother. 46, 2132-2136
28. David, S. A., Awasthi, S. K., and Balaram, P. (2000) J. Endotoxin Res. 6, 249-256
29. Scott, M. G., Vreugdenhil, A. C., Buurman, W. A., Hancock, R. E., and Gold, M. R. (2000) J. Immunol. 164, 549-553
30. Nagaoka, I., Hirota, S., Niyonsaba, F., Hirata, M., Adachi, Y., Tamura, H., Tanaka, S., and Heumann, D. (2002) Clin. Diagn. Lab. Immunol. 9, 972-982
31. Pouny, Y., and Shai, Y. (1992) Biochemistry 31, 9482-9490
32. Rapaport, D., and Shai, Y. (1991) J. Biol. Chem. 266, 23769-23775
33. Tobias, P. S., Soldau, K., Gegner, J. A., Mintz, D., and Ulevitch, R. J. (1995) J. Biol. Chem. 270, 10482-10488
34. de Haas, C. J., van Leeuwen, H. J., Verhoef, J., van Kessel, K. P., and van Strijp, J. A. (2000) J. Immunol. Methods 242, 79-89
35. Schiffer, M., and Edmundson, A. B. (1967) Biophys. J. 7, 121-135
36. Frey, S., and Tamm, L. K. (1990) Biochem. J. 272, 713-719
37. Wang, P. Y., Kitchens, R. L., and Munford, R. S. (1995) J. Inflamm. 47, 126-137
38. Papo, N., and Shai, Y. (2003) Biochemistry 42, 458-466
39. Nagaoka, I., Hirota, S., Niyonsaba, F., Hirata, M., Adachi, Y., Tamura, H., and Heumann, D. (2001) J. Immunol. 167, 3329-3338
40. Takayama, K., Mitchell, D. H., Din, Z. Z., Mukerjee, P., Li, C., and Coleman, D. L. (1994) J. Biol. Chem. 269, 2241-2244
41. Alexander, C., and Rietschel, E. T. (2001) J. Endotoxin Res. 7, 167-202
42. Andra, J., Koch, M. H., Bartels, R., and Brandenburg, K. (2004) Antimicrob. Agents Chemother. 48, 1593-1599
43. Oren, Z., and Shai, Y. (1997) Biochemistry 36, 1826-1835
44. Papo, N., Oren, Z., Pag, U., Sahl, H. G., and Shai, Y. (2002) J. Biol. Chem. 277, 33913-33921