The structure of the human βII-tryptase tetramer: Fo(u)r better or worse

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 20, 1999, Pages 10984-10991

  Sommerhoff, Christian P ^a   Bode, Wolfram ^b   Pereira, Pedro J B ^b   Stubbs, Milton T ^c   Stürzebecher, Jörg ^d   Piechottka, Gerd P ^a   Matschiner, Gabriele ^a   Bergner, Andreas ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c Pharmazeutisch Chemisches Inst P   (Germany)

^d Klinikum der Universitat Jena   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME PRECURSOR; HEPARIN; MONOMER; PHENYLPYRUVIC ACID; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; TETRAMER; TRYPTASE; CHYMASE; CHYMASE 2;

ALLERGIC ASTHMA; CONFERENCE PAPER; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; INFLAMMATION; MACROMOLECULE; MAST CELL; MEDIATOR RELEASE; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; CRYSTALLOGRAPHY; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; CHYMASES; CRYSTALLOGRAPHY; HUMANS; MOLECULAR SEQUENCE DATA; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; TRYPTASES;

EID: 0033612961     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.20.10984     Document Type: Article

References (49)

1. Miller, J. S., Westin, E. H. & Schwartz, L. B. (1989) J. Clin. Invest. 84, 1188-1195.
2. Pallaoro, M., Fejzo, M. S., Shayesteh, L., Blount, J. L. & Caughey, G. H. (1999) J. Biol. Chem. 274, 3355-3362.
3. Schwartz, L. B., Irani, A. M., Roller, K., Castells, M. C. & Schechter, N. M. (1987) J. Immunol. 138, 2611-2615.
4. Xia, H. Z., Kepley, C. L., Sakai, K., Chelliah, J., Irani, A. M. & Schwartz, L. B. (1995) J. Immunol. 154, 5472-5480.
5. Schwartz, L. B., Sakai, K., Bradford, T. R., Ren, S., Zweiman, B., Worobec, A. S. & Metcalfe, D. D. (1995) J. Clin. Invest. 96, 2702-2710.
6. Sakai, K., Ren, S. & Schwartz, L. B. (1996) J. Clin. Invest. 97, 988-995.
7. Caughey, G. H. (1997) Am. J. Respir. Cell Mol. Biol. 16, 621-628.
8. Johnson, P. R. A., Ammit, A. J., Carlin, S. M., Armour, C. L., Caughey, G. H. & Black, J. L. (1997) Eur. Respir. J. 10, 38-43.
9. Rice, K. D., Tanaka, R. D., Katz, B. A., Numerof, R. P. & Moore, W. R. (1998) Curr. Pharm. Des. 4, 381-396.
10. De Sanctis, G. T., Merchant, M., Beier, D. R., Dredge, R. D., Grobholz, J. K., Martin, T. R., Lander, E. S. & Drazen, J. M. (1995) Nat. Genet. 11, 150-154.
11. Hunt, J. E., Stevens, R. L., Austen, K. F., Zhang, J., Xia, Z. & Ghildyal, N. (1996) J. Biol. Chem. 271, 2851-2855.
12. Schwartz, L. B. (1994) Methods Enzymol. 244, 88-100.
13. Caughey, G. H. (1995) Mast Cell Proteases in Immunology and Biology (Dekker, New York).
14. Ren, S., Sakai, K. & Schwartz, L. B. (1998) J. Immunol. 160, 4561-4569.
15. Selwood, T., McCaslin, D. R. & Schechter, N. M. (1998) Biochemistry 37, 13174-13183.
16. Sommerhoff, C. P., Söllner, C., Mentele, R., Piechottka, G. P., Auerswald, E. A. & Fritz, H. (1994) Biol. Chem. Hoppe-Seyler 375, 685-694.
17. Stubbs, M. T., Morenweiser, R., Stürzebecher, J., Bauer, M., Bode, W., Huber, R., Piechottka, G. P., Matschiner, G., Sommerhoff, C. P., Fritz, H., et al. (1997) J. Biol. Chem. 272, 19931-19937.
18. Tam, E. K. & Caughey, G. H. (1990) Am. J. Respir. Cell Mol. Biol. 3, 27-32.
19. Gruber, B. L., Marchese, M. J., Suzuki, K., Schwartz, L. B., Okada, Y., Nagase, H. & Ramamurthy, N. S. (1989) J. Clin. Invest. 84, 1657-1662.
20. Stack, M. S. & Johnson, D. A. (1994) J. Biol. Chem. 269, 9416-9419.
21. Molino, M., Barnathan, E. S., Numerof, R., Clark, J., Dreyer, M., Cumashi, A., Hoxie, J. A., Schechter, N., Woolkalis, M. & Brass, L. F. (1997) J. Biol. Chem. 272, 4043-4049.
22. Lohi, J., Harvima, I. & Keski-Oja, J. (1992) J. Cell. Biochem. 50, 337-349.
23. Little, S. S. & Johnson, D. A. (1995) Biochem. J. 307, 341-346.
24. Schwartz, L. B., Bradford, T. R., Littman, B. H. & Wintroub, B. U. (1985) J. Immunol. 135, 2762-2767.
25. Pereira, P. J., Bergner, A., Macedo-Ribeiro, S., Huber, R., Matschiner, G., Fritz, H., Sommerhoff, C. P. & Bode, W. (1998) Nature (London) 392, 306-311.
26. Blevins, R. A. & Tulinsky, A. (1985) J. Biol. Chem. 260, 4264-4275.
27. Bode, W. & Schwager, P. (1975) J. Mol. Biol. 98, 693-717.
28. Wang, D., Bode, W. & Huber, R. (1985) J. Mol. Biol. 185, 595-624.
29. Renatus, M., Engh, R. A., Stubbs, M. T., Huber, R., Fischer, S., Kohnert, U. & Bode, W. (1997) EMBO J. 16, 4797-4805.
30. Huber, R. & Bode, W. (1978) Acc. Chem. Res. 11, 114-122.
31. Bode, W. (1979) J. Mol. Biol. 127, 357-374.
32. Freer, S. T., Kraut, J., Robertus, J. D., Wright, H. A. T. & Xuong, N. H. (1970) Biochemistry 9, 1997-2009.
33. Bode, W., Fehlhammer, H. & Huber, R. (1976) J. Mol. Biol. 106, 325-335.
34. Hedstrom, L., Lin, T. Y. & Fast, W. (1996) Biochemistry 35, 4515-4523.
35. Bode, W., Schwager, P. & Huber, R. (1978) J. Mol. Biol. 118, 99-112.
36. Bolognesi, M., Gatti, G., Menagatti, E., Guarneri, M., Marquart, M., Papamokos, E. & Huber, R. (1982) J. Mol. Biol. 162, 839-868.
37. Higashi, S. & Iwanaga, S. (1998) Int. J. Hematol. 67, 229-241.
38. Pignol, D., Gaboriaud, C., Michon, T., Kerfelec, B., Chapus, C. & Fontecilla Camps, J. C. (1994) EMBO J. 13, 1763-1771.
39. Banner, D. W., D'Arcy, A., Chene, C., Winkler, F. W., Guha, A., Konigsberg, W. H., Nemerson, Y. & Kirchhofer, D. (1996) Nature (London) 380, 41-46.
40. Alter, S. C., Metcalfe, D. D., Bradford, T. R. & Schwartz, L. B. (1987) Biochem. J. 248, 821-827.
41. Walter, J. & Bode, W. (1983) Hoppe-Seylers Z. Physiol. Chem. 364, 949-959.
42. Stürzebecher, J., Prasa, D. & Sommerhoff, C. P. (1992) Biol. Chem. Hoppe-Seyler 373, 1025-1030.
43. Caughey, G. H., Raymond, W. W., Bacci, E., Lombardy, R. J. & Tidwell, R. R. (1993) J. Pharmacol. Exp. Ther. 264, 676-682.
44. Katz, B. A., Clark, J. M., Finer Moore, J. S., Jenkins, T. E., Johnson, C. R., Ross, M. J., Luong, C., Moore, W. R. & Stroud, R. M. (1998) Nature (London) 391, 608-612.
45. Becker, J. W., Marcy, A. I., Rokosz, L. L., Axel, M. G., Burbaum, J. J., Fitzgerald, P. M., Cameron, P. M., Esser, C. K., Hagmann, W. K., Hermes, J. D., et al. (1995) Protein Sci. 4, 1966-1976.
46. Bode, W. & Huber, R. (1992) Eur. J. Biochem. 204, 433-451.
47. Grütter, M. G., Fendrich, G., Huber, R. & Bode, W. (1988) EMBO J. 7, 345-351.
48. Tsunemi, M., Matsuura, Y., Sakakibara, S. & Katsube, Y. (1996) Biochemistry 35, 11570-11576.
49. Huber, R., Kukla, D., Bode, W., Schwager, P., Bartels, K., Deisenhofer, J. & Steigemann, W. (1974) J. Mol. Biol. 89, 73-101.