ICAM-1 depletion does not alter retinal vascular development in a model of oxygen-mediated neovascularization

Experimental Eye Research

Volumn 89, Issue 4, 2009, Pages 503-510

  Kociok, Norbert ^a,b   Radetzky, Sven ^b   Krohne, Tim U ^b   Gavranic, Claudia ^a   Liang, Yong ^a   Semkova, Irina ^a   Joussen, Antonia M ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

angiogenesis; cytokine; intercellular adhesion molecule 1 (ICAM 1); receptors; retinopathy of prematurity

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; INTERCELLULAR ADHESION MOLECULE 1; LECTIN; MESSENGER RNA; OXYGEN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LABELING; CONTROLLED STUDY; DISEASE MODEL; ENDOTHELIUM CELL; FEMALE; MALE; MOUSE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; RETINA BLOOD VESSEL; RETINA DEVELOPMENT; RETINA NEOVASCULARIZATION; RETROLENTAL FIBROPLASIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANIMALS; ANOXIA; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFANT, NEWBORN; INTERCELLULAR ADHESION MOLECULE-1; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXYGEN; PROTO-ONCOGENE PROTEINS C-SIS; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; RETINOPATHY OF PREMATURITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 69749091950     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2009.05.005     Document Type: Article

References (39)

1. Aiello L.P., Northrup J.M., Keyt B.A., Takagi H., and Iwamoto M.A. Hypoxic regulation of vascular endothelial growth factor in retinal cells. Arch. Ophthalmol. 113 (1995) 1538-1544
2. Aoki T., Suzuki Y., Nishio K., Suzuki K., Miyata A., Oyamada Y., Mori M., Fujita H., and Yamaguchi K. Effect of antioxidants on hyperoxia-induced ICAM-1 expression in human endothelial cells. Adv.Exp. Med. Biol. 411 (1997) 503-511
3. Asahara T., Chen D., Takahashi T., Fujikawa K., Kearney M., Magner M., Yancopoulos G.D., and Isner J.M. Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ. Res. 83 (1998) 233-240
4. Banin E., Dorrell M.I., Aguilar E., Ritter M.R., Aderman C.M., Smith A.C., Friedlander J., and Friedlander M. T2-TrpRS inhibits preretinal neovascularization and enhances physiological vascular regrowth in OIR as assessed by a new method of quantification. Invest. Ophthalmol.Vis. Sci. 47 (2006) 2125-2134
5. Benjamin L.E., Hemo I., and Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125 (1998) 1591-1598
6. Davies M.H., Eubanks J.P., and Powers M.R. Microglia and macrophages are increased in response to ischemia-induced retinopathy in the mouse retina. Mol.Vis. 12 (2006) 467-477
7. Davis S., Aldrich T.H., Jones P.F., Acheson A., Compton D.L., Jain V., Ryan T.E., Bruno J., Radziejewski C., Maisonpierre P.C., and Yancopoulos G.D. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 87 (1996) 1161-1169
8. Gamble J.R., Drew J., Trezise L., Underwood A., Parsons M., Kasminkas L., Rudge J., Yancopoulos G., and Vadas M.A. Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions. Circ. Res. 87 (2000) 603-607
9. Hackett S.F., Wiegand S., Yancopoulos G., and Campochiaro P.A. Angiopoietin-2 plays an important role in retinal angiogenesis. J. Cell Physiol. 192 (2002) 182-187
10. Ishida S., Yamashiro K., Usui T., Kaji Y., Ogura Y., Hida T., Honda Y., Oguchi Y., and Adamis A.P. Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease. Nat.Med. 9 (2003) 781-788
11. Joussen A.M., Poulaki V., Le M.L., Koizumi K., Esser C., Janicki H., Schraermeyer U., Kociok N., Fauser S., Kirchhof B., Kern T.S., and Adamis A.P. A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J. 18 (2004) 1450-1452
12. Joussen A.M., Poulaki V., Mitsiades N., Stechschulte S.U., Kirchhof B., Dartt D.A., Fong G.H., Rudge J., Wiegand S.J., Yancopoulos G.D., and Adamis A.P. VEGF-Dependent conjunctivalization of the corneal surface. Invest. Ophthalmol. Vis. Sci. 44 (2003) 117-123
13. Joussen A.M., Poulaki V., Qin W., Kirchhof B., Mitsiades N., Wiegand S.J., Rudge J., Yancopoulos G.D., and Adamis A.P. Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo. Am. J. Pathol. 160 (2002) 501-509
14. Joussen A.M., Poulaki V., Tsujikawa A., Qin W., Qaum T., Xu Q., Moromizato Y., Bursell S.E., Wiegand S.J., Rudge J., Ioffe E., Yancopoulos G.D., and Adamis A.P. Suppression of diabetic retinopathy with angiopoietin-1. Am. J. Pathol. 160 (2002) 1683-1693
15. Kim I., Moon S.O., Park S.K., Chae S.W., and Koh G.Y. Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression. Circ. Res. 89 (2001) 477-479
16. Koblizek T.I., Weiss C., Yancopoulos G.D., Deutsch U., and Risau W. Angiopoietin-1 induces sprouting angiogenesis in vitro. Curr. Biol. 8 (1998) 529-532
17. Kociok N., Krohne T.U., Poulaki V., and Joussen A.M. Geldanamycin treatment reduces neovascularization in a mouse model of retinopathy of prematurity. Graefes Arch. Clin. Exp. Ophthalmol. 245 (2007) 258-266
18. Kociok N., Radetzky S., Krohne T.U., Gavranic C., and Joussen A.M. Pathological but not physiological retinal neovascularization is altered in TNF-Rp55 receptor deficinet mice. Invest. Ophthalmol. Vis. Sci. 47 (2006) 5057-5065
19. Maisonpierre P.C., Suri C., Jones P.F., Bartunkova S., Wiegand S.J., Radziejewski C., Compton D., McClain J., Aldrich T.H., Papadopoulos N., Daly T.J., Davis S., Sato T.N., and Yancopoulos G.D. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277 (1997) 55-60
20. Morrison T.B., Weis J.J., and Wittwer C.T. Quantification of low-copy transcripts by continuous SYBR Green I monitoring during amplification. Biotechniques 24 (1998) 954-958 960, 962
21. Mustonen T., and Alitalo K. Endothelial receptor tyrosine kinases involved in angiogenesis. J.Cell Biol. 129 (1995) 895-898
22. Nishio K., Suzuki Y., Aoki T., Suzuki K., Miyata A., Sato N., Naoki K., Kudo H., Tsumura H., Serizawa H., Morooka S., Ishimura Y., Suematsu M., and Yamaguchi K. Differential contribution of various adhesion molecules to leukocyte kinetics in pulmonary microvessels of hyperoxia-exposed rat lungs. Am. J. Respir. Crit. Care Med. 157 (1998) 599-609
23. Papapetropoulos A., Garcia-Cardena G., Dengler T.J., Maisonpierre P.C., Yancopoulos G.D., and Sessa W.C. Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors. Lab. Invest. 79 (1999) 213-223
24. Ramakers C., Ruijter J.M., Deprez R.H., and Moorman A.F. Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data. Neurosci. Lett. (2003) 62-66
25. Reynolds J.D. The management of retinopathy of prematurity. Paediatr. Drugs 3 (2001) 263-272
26. Risau W. Mechanisms of angiogenesis. Nature 386 (1997) 671-674
27. Romashkova J.A., and Makarov S.S. NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature 401 (1999) 86-90
28. Sakurai E., Taguchi H., Anand A., Ambati B.K., Gragoudas E.S., Miller J.W., Adamis A.P., and Ambati J. Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. 44 (2003) 2743-2749
29. Sarlos S., Rizkalla B., Moravski C.J., Cao Z., Cooper M.E., and Wilkinson-Berka J.L. Retinal angiogenesis is mediated by an interaction between the angiotensin type 2 receptor, VEGF, and angiopoietin. Am. J. Pathol. 163 (2003) 879-887
30. Shen J., Xie B., Dong A., Swaim M., Hackett S.F., and Campochiaro P.A. In vivo immunostaining demonstrates macrophages associate with growing and regressing vessels. Invest. Ophthalmol. Vis. Sci. 48 (2007) 4335-4341
31. Smith L.E., Wesolowski E., McLellan A., Kostyk S.K., D'Amato R., Sullivan R., and D'Amore P.A. Oxygen-induced retinopathy in the mouse. Invest. Ophthalmol. Vis. Sci. 35 (1994) 101-111
32. Suri C., Jones P.F., Patan S., Bartunkova S., Maisonpierre P.C., Davis S., Sato T.N., and Yancopoulos G.D. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87 (1996) 1171-1180
33. Thurston G., Rudge J.S., Ioffe E., Zhou H., Ross L., Croll S.D., Glazer N., Holash J., McDonald D.M., and Yancopoulos G.D. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat.Med. 6 (2000) 460-463
34. Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., and Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3 (2002) RESEARCH0034
35. Vikkula M., Boon L.M., Carraway III K.L., Calvert J.T., Diamonti A.J., Goumnerov B., Pasyk K.A., Marchuk D.A., Warman M.L., Cantley L.C., Mulliken J.B., and Olsen B.R. Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2. Cell 87 (1996) 1181-1190
36. Wilkinson-Berka J.L., Babic S., De G.T., Stitt A.W., Jaworski K., Ong L.G., Kelly D.J., and Gilbert R.E. Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy. Am. J. Pathol. 164 (2004) 1263-1273
37. Willam C., Schindler R., Frei U., and Eckardt K.U. Increases in oxygen tension stimulate expression of ICAM-1 and VCAM-1 on human endothelial cells. Am. J. Physiol. 276 (1999) H2044-H2052
38. Witzenbichler B., Maisonpierre P.C., Jones P., Yancopoulos G.D., and Isner J.M. Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2. J. Biol. Chem. 273 (1998) 18514-18521
39. Yokota T., Utsunomiya K., Taniguchi K., Gojo A., Kurata H., and Tajima N. Involvement of the Rho/Rho kinase signaling pathway in platelet-derived growth factor BB-induced vascular endothelial growth factor expression in diabetic rat retina. Jpn. J. Ophthalmol. 51 (2007) 424-430