Geldanamycin treatment reduces neovascularization in a mouse model of retinopathy of prematurity

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 245, Issue 2, 2007, Pages 258-266

  Kociok, Norbert ^a   Krohne, Tim U ^a   Poulaki, Vassiliki ^b   Joussen, Antonia M ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Geldanamycin; Kinase inhibitor; Neovascularization; Retina; Retinopathy of prematurity

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; CONCANAVALIN A; GELDANAMYCIN; MESSENGER RNA; OXYGEN; VASCULOTROPIN; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RETINA; RETINA BLOOD VESSEL; RETINA NEOVASCULARIZATION; RETROLENTAL FIBROPLASIA; SIGNAL TRANSDUCTION;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANIMALS; BENZOQUINONES; DISEASE MODELS, ANIMAL; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; INFANT, NEWBORN; INJECTIONS, INTRAPERITONEAL; LACTAMS, MACROCYCLIC; MALE; MICE; MICE, INBRED C57BL; OXYGEN; PROTEIN-SERINE-THREONINE KINASES; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; RETINOPATHY OF PREMATURITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33847160332     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-006-0355-x     Document Type: Article

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