Involvement of the Rho/Rho kinase signaling pathway in platelet-derived growth factor BB-induced vascular endothelial growth factor expression in diabetic rat retina

Japanese Journal of Ophthalmology

Volumn 51, Issue 6, 2007, Pages 424-430

  Yokota, Tamotsu ^a,b   Utsunomiya, Kazunori ^a   Taniguchi, Kanta ^a   Gojo, Atsushi ^a   Kurata, Hideaki ^a   Tajima, Naoko ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE   (Japan)

Author keywords

Diabetic retinopathy; Fasudil; Pericytes; Rho; Vascular endothelial growth factor

Indexed keywords

FASUDIL; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR BB; RHO KINASE; RHO KINASE INHIBITOR; STREPTOZOCIN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES CONTROL; DIABETIC RETINOPATHY; ENZYME ACTIVATION; MALE; NONHUMAN; NORTHERN BLOTTING; PERICYTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; UPREGULATION; WESTERN BLOTTING;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANGIOGENESIS INDUCING AGENTS; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; FATTY ACIDS, MONOUNSATURATED; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INDOLES; MALE; PERICYTES; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RETINAL VESSELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; SWINE; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 37549062567     PISSN: 00215155     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10384-007-0471-0     Document Type: Article

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