-
1
-
-
38349049307
-
Neuropathology for the neuroradiologist: Plaques and tangles
-
Wippold FJ 2nd, Cairns N, Vo K, Holtzman DM, Morris JC: Neuropathology for the neuroradiologist: Plaques and tangles. AJNR Am J Neuroradiol (2008) 29(1):18-22.
-
(2008)
AJNR Am J Neuroradiol
, vol.29
, Issue.1
, pp. 18-22
-
-
Wippold 2nd, F.J.1
Cairns, N.2
Vo, K.3
Holtzman, D.M.4
Morris, J.C.5
-
2
-
-
0025753852
-
-
Selkoe DJ: The molecular pathology of Alzheimer's disease. Neuron (1991) 6(4):487-498.**Seminal paper to posit the amyloid hypothesis, drawing significantly from genetic studies to support this hypothesis.
-
Selkoe DJ: The molecular pathology of Alzheimer's disease. Neuron (1991) 6(4):487-498.**Seminal paper to posit the amyloid hypothesis, drawing significantly from genetic studies to support this hypothesis.
-
-
-
-
3
-
-
0028123071
-
Alzheimer's disease: A central role for amyloid
-
Selkoe DJ: Alzheimer's disease: A central role for amyloid. J Neuropathol Exp Neurol (1994) 53(5):438-447.
-
(1994)
J Neuropathol Exp Neurol
, vol.53
, Issue.5
, pp. 438-447
-
-
Selkoe, D.J.1
-
4
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ: The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science (2002) 297(5580):353-356.
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
5
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy JA, Higgins GA: Alzheimer's disease: The amyloid cascade hypothesis. Science (1992) 256(5054):184-185.
-
(1992)
Science
, vol.256
, Issue.5054
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
6
-
-
56349144614
-
11C]PIB-PET study
-
11C]PIB-PET study. Neurobiol Dis (2008) 32(3):412-419.
-
(2008)
Neurobiol Dis
, vol.32
, Issue.3
, pp. 412-419
-
-
Edison, P.1
Archer, H.A.2
Gerhard, A.3
Hinz, R.4
Pavese, N.5
Turkheimer, F.E.6
Hammers, A.7
Tai, Y.F.8
Fox, N.9
Kennedy, A.10
Rossor, M.11
-
7
-
-
12644258498
-
141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue
-
141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue. Proc Natl Acad Sci USA (1997) 94(5):2025- 2030.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.5
, pp. 2025-2030
-
-
Tomita, T.1
Maruyama, K.2
Saido, T.C.3
Kume, H.4
Shinozaki, K.5
Tokuhiro, S.6
Capell, A.7
Walter, J.8
Grunberg, J.9
Haass, C.10
Iwatsubo, T.11
-
8
-
-
0031003233
-
The Alzheimer family of diseases: Many etiologies, one pathogenesis?
-
Hardy J: The Alzheimer family of diseases: Many etiologies, one pathogenesis? Proc Natl Acad Sci USA (1997) 94(6):2095-2097.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.6
, pp. 2095-2097
-
-
Hardy, J.1
-
9
-
-
8644240928
-
Vascular pathologies and cognition in a population-based cohort of elderly people
-
Fernando MS, Ince PG: Vascular pathologies and cognition in a population-based cohort of elderly people. J Neurol Sci (2004) 226(1-2):13-17.
-
(2004)
J Neurol Sci
, vol.226
, Issue.1-2
, pp. 13-17
-
-
Fernando, M.S.1
Ince, P.G.2
-
10
-
-
34447275455
-
42 levels, incident dementia, and mortality in Down syndrome
-
42 levels, incident dementia, and mortality in Down syndrome. Arch Neurol (2007) 64(7):1007-1013.
-
(2007)
Arch Neurol
, vol.64
, Issue.7
, pp. 1007-1013
-
-
Schupf, N.1
Patel, B.2
Pang, D.3
Zigman, W.B.4
Silverman, W.5
Mehta, P.D.6
Mayeux, R.7
-
11
-
-
66049148147
-
Biological CSF markers of Alzheimer's disease
-
Zetterberg H, Blennow K: Biological CSF markers of Alzheimer's disease. Handb Clin Neurol (2008) 89:261-268.
-
(2008)
Handb Clin Neurol
, vol.89
, pp. 261-268
-
-
Zetterberg, H.1
Blennow, K.2
-
12
-
-
33847204043
-
42, tau and phosphorylated tau, APOE ε4 allele and MCI type in progressive MCI
-
42, tau and phosphorylated tau, APOE ε4 allele and MCI type in progressive MCI. Neurobiol Aging (2007) 28(4):507-514.
-
(2007)
Neurobiol Aging
, vol.28
, Issue.4
, pp. 507-514
-
-
Herukka, S.K.1
Helisalmi, S.2
Hallikainen, M.3
Tervo, S.4
Soininen, H.5
Pirttila, T.6
-
13
-
-
37349026227
-
Multicenter assessment of CSF-phosphorylated tau for the prediction of conversion of MCI
-
Ewers M, Buerger K, Teipel SJ, Scheltens P, Schroder J, Zinkowski RP, Bouwman FH, Schonknecht P, Schoonenboom NS, Andreasen N, Wallin A et al: Multicenter assessment of CSF-phosphorylated tau for the prediction of conversion of MCI. Neurology (2007) 69(24):2205-2212.
-
(2007)
Neurology
, vol.69
, Issue.24
, pp. 2205-2212
-
-
Ewers, M.1
Buerger, K.2
Teipel, S.J.3
Scheltens, P.4
Schroder, J.5
Zinkowski, R.P.6
Bouwman, F.H.7
Schonknecht, P.8
Schoonenboom, N.S.9
Andreasen, N.10
Wallin, A.11
-
14
-
-
38149081191
-
Imaging of amyloid β in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: Proof of mechanism
-
Rowe CC, Ackerman U, Browne W, Mulligan R, Pike KL, O'Keefe G, Tochon-Danguy H, Chan G, Berlangieri SU, Jones G, Dickinson-Rowe KL et al: Imaging of amyloid β in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: Proof of mechanism. Lancet Neurol (2008) 7(2):129-135.
-
(2008)
Lancet Neurol
, vol.7
, Issue.2
, pp. 129-135
-
-
Rowe, C.C.1
Ackerman, U.2
Browne, W.3
Mulligan, R.4
Pike, K.L.5
O'Keefe, G.6
Tochon-Danguy, H.7
Chan, G.8
Berlangieri, S.U.9
Jones, G.10
Dickinson-Rowe, K.L.11
-
15
-
-
33644832047
-
-
42 levels in the CSF.
-
42 levels in the CSF.
-
-
-
-
16
-
-
56749112290
-
The future of amyloid-β imaging: A tale of radionuclides and tracer proliferation
-
Klunk WE, Mathis CA: The future of amyloid-β imaging: A tale of radionuclides and tracer proliferation. Curr Opin Neurol (2008) 21(6):683-687.
-
(2008)
Curr Opin Neurol
, vol.21
, Issue.6
, pp. 683-687
-
-
Klunk, W.E.1
Mathis, C.A.2
-
18
-
-
34447326955
-
Amyloid imaging in Alzheimer's disease
-
Nordberg A: Amyloid imaging in Alzheimer's disease. Curr Opin Neurol (2007) 20(4):398-402.
-
(2007)
Curr Opin Neurol
, vol.20
, Issue.4
, pp. 398-402
-
-
Nordberg, A.1
-
20
-
-
47949132196
-
Active and passive immunotherapy for neurodegenerative disorders
-
Brody DL, Holtzman DM: Active and passive immunotherapy for neurodegenerative disorders. Annu Rev Neurosci (2008) 31:175-193.
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 175-193
-
-
Brody, D.L.1
Holtzman, D.M.2
-
21
-
-
33646384419
-
Immunology and immunotherapy of Alzheimer's disease
-
Weiner HL, Frenkel D: Immunology and immunotherapy of Alzheimer's disease. Nat Rev Immunol (2006) 6(5):404-416.
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.5
, pp. 404-416
-
-
Weiner, H.L.1
Frenkel, D.2
-
22
-
-
70349123872
-
O3-05-02: EHT-0202: A neuroprotective and procognitive α-secretase stimulator targeted towards Alzheimer disease therapy
-
Abs O3-05-02
-
Desire L, Buee L, Lambeng N, Drouin D, Schweighoffer F: O3-05-02: EHT-0202: A neuroprotective and procognitive α-secretase stimulator targeted towards Alzheimer disease therapy. Alzheimer's and Dementia (2008) 4(4 Suppl 1):Abs O3-05-02.
-
(2008)
Alzheimer's and Dementia
, vol.4
, Issue.4 SUPPL. 1
-
-
Desire, L.1
Buee, L.2
Lambeng, N.3
Drouin, D.4
Schweighoffer, F.5
-
24
-
-
20944448555
-
-
Gilman S, Koller M, Black RS, Jenkins L, Griffith SG, Fox NC, Eisner L, Kirby L, Rovira MB, Forette F, Orgogozo JM: Clinical effects of β immunization (AN1792) in patients with AD in an interrupted trial. Neurology (2005) 64(9):1553-1562. * First paper to comprehensively describe the overall clinical outcome in patients with AD, who received from one to three administrations of AN-1792 (n = 300) or placebo (n = 72) and were followed for a minimum of 9 months after the last injection.
-
Gilman S, Koller M, Black RS, Jenkins L, Griffith SG, Fox NC, Eisner L, Kirby L, Rovira MB, Forette F, Orgogozo JM: Clinical effects of β immunization (AN1792) in patients with AD in an interrupted trial. Neurology (2005) 64(9):1553-1562. * First paper to comprehensively describe the overall clinical outcome in patients with AD, who received from one to three administrations of AN-1792 (n = 300) or placebo (n = 72) and were followed for a minimum of 9 months after the last injection.
-
-
-
-
25
-
-
67650409845
-
S2-04-06: Safety, tolerability and immunogenicity of the Aβ immunotherapeutic vaccine CAD106 in a first-in-man study in Alzheimer patients
-
Abs S2-04-06
-
Winblad B: S2-04-06: Safety, tolerability and immunogenicity of the Aβ immunotherapeutic vaccine CAD106 in a first-in-man study in Alzheimer patients. Alzheimer;s and Dementia (2008) 4(4 Suppl 1):Abs S2-04-06.
-
(2008)
Alzheimer;s and Dementia
, vol.4
, Issue.4 SUPPL. 1
-
-
Winblad, B.1
-
26
-
-
69249125588
-
-
Annual Report , March 14
-
Wyeth: Annual report 2001. Annual Report (2002): March 14.
-
(2002)
Annual report 2001
-
-
Wyeth1
-
27
-
-
46749113799
-
Targeting β-amyloid pathology in Alzheimer's disease with Aβ immunotherapy
-
Nitsch RM, Hock C: Targeting β-amyloid pathology in Alzheimer's disease with Aβ immunotherapy. Neurotherapeutics (2008) 5(3):415-420.
-
(2008)
Neurotherapeutics
, vol.5
, Issue.3
, pp. 415-420
-
-
Nitsch, R.M.1
Hock, C.2
-
28
-
-
0035123370
-
The functions of the amyloid precursor protein gene
-
Panegyres PK: The functions of the amyloid precursor protein gene. Rev Neurosci (2001) 12(1):1-39.
-
(2001)
Rev Neurosci
, vol.12
, Issue.1
, pp. 1-39
-
-
Panegyres, P.K.1
-
29
-
-
69249138938
-
Passive immunotherapies as an approach to disease modification in Alzheimer's disease
-
Chicago, IL, USA
-
Morgan D: Passive immunotherapies as an approach to disease modification in Alzheimer's disease. Satellite Symposium International Conference on Alzheimer's Disease, Chicago, IL, USA (2008).
-
(2008)
Satellite Symposium International Conference on Alzheimer's Disease
-
-
Morgan, D.1
-
30
-
-
33745111586
-
Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice
-
Carty NC, Wilcock DM, Rosenthal A, Grimm J, Pons J, Ronan V, Gottschall PE, Gordon MN, Morgan D: Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice. J Neuroinflammation (2006) 3:11.
-
(2006)
J Neuroinflammation
, vol.3
, pp. 11
-
-
Carty, N.C.1
Wilcock, D.M.2
Rosenthal, A.3
Grimm, J.4
Pons, J.5
Ronan, V.6
Gottschall, P.E.7
Gordon, M.N.8
Morgan, D.9
-
31
-
-
33745001453
-
Deglycosylated anti-amyloid-β antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice
-
Wilcock DM, Alamed J, Gottschall PE, Grimm J, Rosenthal A, Pons J, Ronan V, Symmonds K, Gordon MN, Morgan D: Deglycosylated anti-amyloid-β antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice. J Neurosci (2006) 26(20):5340-5346.
-
(2006)
J Neurosci
, vol.26
, Issue.20
, pp. 5340-5346
-
-
Wilcock, D.M.1
Alamed, J.2
Gottschall, P.E.3
Grimm, J.4
Rosenthal, A.5
Pons, J.6
Ronan, V.7
Symmonds, K.8
Gordon, M.N.9
Morgan, D.10
-
32
-
-
69249112464
-
Safety and pharmacokinetics of the anti-amyloid monoclonal antibody PF-04360365 following a single infusion in patients with mild-to-moderate Alzheimer's Disease: Preliminary results
-
Bednar MM, Zhao Q, Landen JW, Billing CB, Rohrbacher K, Kupiec JW: Safety and pharmacokinetics of the anti-amyloid monoclonal antibody PF-04360365 following a single infusion in patients with mild-to-moderate Alzheimer's Disease: Preliminary results. Alzheimer Dementia (2009) 5(4):P157.
-
(2009)
Alzheimer Dementia
, vol.5
, Issue.4
-
-
Bednar, M.M.1
Zhao, Q.2
Landen, J.W.3
Billing, C.B.4
Rohrbacher, K.5
Kupiec, J.W.6
-
33
-
-
65549113533
-
Suppression of amyloid deposition leads to long-term reductions in Alzheimer's pathologies in Tg2576 mice
-
Karlnoski RA, Rosenthal A, Kobayashi D, Pons J, Alamed J, Mercer M, Li Q, Gordon MN, Gottschall PE, Morgan D: Suppression of amyloid deposition leads to long-term reductions in Alzheimer's pathologies in Tg2576 mice. J Neurosci (2009) 29(15):4964-4971.
-
(2009)
J Neurosci
, vol.29
, Issue.15
, pp. 4964-4971
-
-
Karlnoski, R.A.1
Rosenthal, A.2
Kobayashi, D.3
Pons, J.4
Alamed, J.5
Mercer, M.6
Li, Q.7
Gordon, M.N.8
Gottschall, P.E.9
Morgan, D.10
-
34
-
-
60549107033
-
A specific enzyme-linked immunosorbent assay for measuring β-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease
-
Xia W, Yang T, Shankar G, Smith IM, Shen Y, Walsh DM, Selkoe DJ: A specific enzyme-linked immunosorbent assay for measuring β-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease. Arch Neurol (2009) 66(2):190-199.
-
(2009)
Arch Neurol
, vol.66
, Issue.2
, pp. 190-199
-
-
Xia, W.1
Yang, T.2
Shankar, G.3
Smith, I.M.4
Shen, Y.5
Walsh, D.M.6
Selkoe, D.J.7
-
35
-
-
69249125589
-
Tissue-type plasminogen activator promotes amyloid degradation
-
Abs 876.11
-
Cacquevel M, Chéenne S, Lesne S, Carmeliet P, Buée L, Delacourte A, Bernaudin M, Buisson A, Vivien D: Tissue-type plasminogen activator promotes amyloid degradation. Society for Neuroscience Annual Meeting (2003) 33:Abs 876.11.
-
(2003)
Society for Neuroscience Annual Meeting
, vol.33
-
-
Cacquevel, M.1
Chéenne, S.2
Lesne, S.3
Carmeliet, P.4
Buée, L.5
Delacourte, A.6
Bernaudin, M.7
Buisson, A.8
Vivien, D.9
-
36
-
-
60549094292
-
P2-393: Increasing the efficacy of immunotherapy for Alzheimer's disease (AD) with intravenous immunoglobulin (IVIG)
-
Abs P2-393
-
Szabo P, Esteban M, Monthe C, White L, Lent R, Relkin N, Weksler M: P2-393: Increasing the efficacy of immunotherapy for Alzheimer's disease (AD) with intravenous immunoglobulin (IVIG). Alzheimer's and Dementia (2006) 2(3 Suppl 1):Abs P2-393.
-
(2006)
Alzheimer's and Dementia
, vol.2
, Issue.3 SUPPL. 1
-
-
Szabo, P.1
Esteban, M.2
Monthe, C.3
White, L.4
Lent, R.5
Relkin, N.6
Weksler, M.7
-
37
-
-
33846080463
-
Drug insight: The use of intravenous immunoglobulin in neurology Therapeutic considerations and practical issues
-
Gold R, Stangel M, Dalakas MC: Drug insight: The use of intravenous immunoglobulin in neurology Therapeutic considerations and practical issues. Nat Clin Pract Neurol (2007) 3(1):36-44.
-
(2007)
Nat Clin Pract Neurol
, vol.3
, Issue.1
, pp. 36-44
-
-
Gold, R.1
Stangel, M.2
Dalakas, M.C.3
-
38
-
-
19944431509
-
Exacerbation of cerebral amyloid angiopathyassociated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid β
-
Racke MM, Boone LI, Hepburn DL, Parsadainian M, Bryan MT, Ness DK, Piroozi KS, Jordan WH, Brown DD, Hoffman WP, Holtzman DM et al: Exacerbation of cerebral amyloid angiopathyassociated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid β. J Neurosci (2005) 25(3):629-636.
-
(2005)
J Neurosci
, vol.25
, Issue.3
, pp. 629-636
-
-
Racke, M.M.1
Boone, L.I.2
Hepburn, D.L.3
Parsadainian, M.4
Bryan, M.T.5
Ness, D.K.6
Piroozi, K.S.7
Jordan, W.H.8
Brown, D.D.9
Hoffman, W.P.10
Holtzman, D.M.11
-
39
-
-
0037452779
-
Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology
-
Bard F, Barbour R, Cannon C, Carretto R, Fox M, Games D, Guido T, Hoenow K, Hu K, Johnson-Wood K, Khan K et al: Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology. Proc Natl Acad Sci USA (2003) 100(4):2023-2028.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.4
, pp. 2023-2028
-
-
Bard, F.1
Barbour, R.2
Cannon, C.3
Carretto, R.4
Fox, M.5
Games, D.6
Guido, T.7
Hoenow, K.8
Hu, K.9
Johnson-Wood, K.10
Khan, K.11
-
40
-
-
76849117025
-
S1-02-02: Natural human antibodies targeting amyloid aggregates in intravenous immunoglobulin
-
Abs S1-02-02
-
Relkin NR: S1-02-02: Natural human antibodies targeting amyloid aggregates in intravenous immunoglobulin. Alzheimer's and Dementia (2008) 4(4 Suppl 1):Abs S1-02-02.
-
(2008)
Alzheimer's and Dementia
, vol.4
, Issue.4 SUPPL. 1
-
-
Relkin, N.R.1
-
41
-
-
0035979145
-
Aβ immunization: Moving Aβ peptide from brain to blood
-
Lee VMY: Aβ immunization: Moving Aβ peptide from brain to blood. Proc Natl Acad Sci USA (2001) 98(16):8931-8932.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.16
, pp. 8931-8932
-
-
Lee, V.M.Y.1
-
42
-
-
0035902619
-
-
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM: Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA (2001) 98(15):8850-8855. ** Studying PDAPP (PDGF promoter expressing APP) transgenic mice, a rise in Aβ levels in the plasma of > 1000-fold was observed after the peripheral administration of a mAb targeting amyloid. This rise in Aβ was due, in part, to the peripheral effects of the mAb that altered the clearance of amyloid from the CNS.
-
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM: Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA (2001) 98(15):8850-8855. ** Studying PDAPP (PDGF promoter expressing APP) transgenic mice, a rise in Aβ levels in the plasma of > 1000-fold was observed after the peripheral administration of a mAb targeting amyloid. This rise in Aβ was due, in part, to the peripheral effects of the mAb that altered the clearance of amyloid from the CNS.
-
-
-
-
43
-
-
52649157170
-
Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid β-protein in perivascular astrocytes
-
Utter S, Tamboli IY, Walter J, Upadhaya AR, Birkenmeier G, Pietrzik CU, Ghebremedhin E, Thal DR: Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid β-protein in perivascular astrocytes. J Neuropathol Exp Neurol (2008) 67(9):842-856.
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, Issue.9
, pp. 842-856
-
-
Utter, S.1
Tamboli, I.Y.2
Walter, J.3
Upadhaya, A.R.4
Birkenmeier, G.5
Pietrzik, C.U.6
Ghebremedhin, E.7
Thal, D.R.8
-
44
-
-
34249040510
-
Blood-brain barrier impairment in Alzheimer disease: Stability and functional significance
-
Bowman GL, Kaye JA, Moore M, Waichunas D, Carlson NE, Quinn JF: Blood-brain barrier impairment in Alzheimer disease: Stability and functional significance. Neurology (2007) 68(21):1809-1814.
-
(2007)
Neurology
, vol.68
, Issue.21
, pp. 1809-1814
-
-
Bowman, G.L.1
Kaye, J.A.2
Moore, M.3
Waichunas, D.4
Carlson, N.E.5
Quinn, J.F.6
-
45
-
-
33750874717
-
Vaccine development for Alzheimer's disease
-
DaSilva KA, Aubert I, McLaurin JA: Vaccine development for Alzheimer's disease. Curr Pharm Des (2006) 12(33):4283-4293.
-
(2006)
Curr Pharm Des
, vol.12
, Issue.33
, pp. 4283-4293
-
-
DaSilva, K.A.1
Aubert, I.2
McLaurin, J.A.3
-
46
-
-
49149124343
-
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM et al: Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med (2008) 14(8):837-842.
-
(2008)
Nat Med
, vol.14
, Issue.8
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
-
47
-
-
0032590054
-
Soluble pool of Aβ amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, Bush AI, Masters CL: Soluble pool of Aβ amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol (1999) 46(6):860-866.
-
(1999)
Ann Neurol
, vol.46
, Issue.6
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
48
-
-
47149112621
-
-
42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebo-controlled phase I trial. Lancet (2008) 372(9634):216-223. * A thought-provoking paper on the cognitive-histopathological relationship of a group of patients immunized with AN-1793 who were followed until death; results of the post-mortem autopsy were also analyzed.
-
42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebo-controlled phase I trial. Lancet (2008) 372(9634):216-223. * A thought-provoking paper on the cognitive-histopathological relationship of a group of patients immunized with AN-1793 who were followed until death; results of the post-mortem autopsy were also analyzed.
-
-
-
-
49
-
-
0036240395
-
-
Dodart JC, Bales KR, Gannon KS, Greene SJ, DeMattos RB, Mathis C, DeLong CA, Wu S, Wu X, Holtzman DM, Paul SM: Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model. Nat Neurosci (2002) 5(5):452-457. * Provides evidence that the reversal of memory deficits in transgenic mice may be affected by alterations in soluble amyloid rather than insoluble brain amyloid.
-
Dodart JC, Bales KR, Gannon KS, Greene SJ, DeMattos RB, Mathis C, DeLong CA, Wu S, Wu X, Holtzman DM, Paul SM: Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model. Nat Neurosci (2002) 5(5):452-457. * Provides evidence that the reversal of memory deficits in transgenic mice may be affected by alterations in soluble amyloid rather than insoluble brain amyloid.
-
-
-
-
50
-
-
35648932901
-
β-amyloid imaging and memory in non-demented individuals: Evidence for preclinical Alzheimer's disease
-
Pike KE, Savage G, Villemagne VL, Ng S, Moss SA, Maruff P, Mathis CA, Klunk WE, Masters CL, Rowe CC: β-amyloid imaging and memory in non-demented individuals: Evidence for preclinical Alzheimer's disease. Brain (2007) 130(Pt 11):2837-2844.
-
(2007)
Brain
, vol.130
, Issue.PART 11
, pp. 2837-2844
-
-
Pike, K.E.1
Savage, G.2
Villemagne, V.L.3
Ng, S.4
Moss, S.A.5
Maruff, P.6
Mathis, C.A.7
Klunk, W.E.8
Masters, C.L.9
Rowe, C.C.10
-
51
-
-
65249163018
-
O3-04-05: Clinical trials of bapineuzumab, a β-amyloid-targeted immunotherapy in patients with mild to moderate Alzheimer's disease
-
Abs O3-04-05
-
Grundman M, Black R: O3-04-05: Clinical trials of bapineuzumab, a β-amyloid-targeted immunotherapy in patients with mild to moderate Alzheimer's disease. Alzheimer's and Dementia (2008) 4(4 Suppl 1):Abs O3-04-05.
-
(2008)
Alzheimer's and Dementia
, vol.4
, Issue.4 SUPPL. 1
-
-
Grundman, M.1
Black, R.2
-
52
-
-
1542268242
-
-
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE: Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. Arch Neurol (2004) 61(3):378-384. * Human cognitive-neuropathological correlation from the Religious Orders Study, which provided evidence that tau may be the downstream mediator for the cognitive decline previously associated with the more proximal event of amyloid deposition.
-
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE: Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. Arch Neurol (2004) 61(3):378-384. * Human cognitive-neuropathological correlation from the Religious Orders Study, which provided evidence that tau may be the downstream mediator for the cognitive decline previously associated with the more proximal event of amyloid deposition.
-
-
-
-
54
-
-
65249091605
-
P4-346: Safety, tolerability and biomarker effects of an Aβ monoclonal antibody administered to patients with Alzheimer's disease
-
Abs P4-346
-
Siemers ER, Friedrich S, Dean RA, Sethuraman G, DeMattos R, Jennings D, Tamagnan G, Marek K, Seibyl J: P4-346: Safety, tolerability and biomarker effects of an Aβ monoclonal antibody administered to patients with Alzheimer's disease. Alzheimer's and Dementia (2008) 4(4 Suppl 1):Abs P4-346.
-
(2008)
Alzheimer's and Dementia
, vol.4
, Issue.4 SUPPL. 1
-
-
Siemers, E.R.1
Friedrich, S.2
Dean, R.A.3
Sethuraman, G.4
DeMattos, R.5
Jennings, D.6
Tamagnan, G.7
Marek, K.8
Seibyl, J.9
-
55
-
-
70049083865
-
-
Relkin NR, Szabo P, Adamiak B, Burgut T, Monthe C, Lent RW, Younkin S, Younkin L, Schiff R, Weksler ME: 18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease. Neurobiol Aging (2008):doi:10.1016/j.neurobiolaging.2007.12.021 * Despite a small patient population (n = 8), this study demonstrates an association of cognitive improvement/stabilization with changes in Aβ levels in the plasma and CSF during IVIg administration, with reversion to baseline during a 3-month withdrawal period that occurred between a 6-month and a 9-month IVIg dosing period.
-
Relkin NR, Szabo P, Adamiak B, Burgut T, Monthe C, Lent RW, Younkin S, Younkin L, Schiff R, Weksler ME: 18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease. Neurobiol Aging (2008):doi:10.1016/j.neurobiolaging.2007.12.021 * Despite a small patient population (n = 8), this study demonstrates an association of cognitive improvement/stabilization with changes in Aβ levels in the plasma and CSF during IVIg administration, with reversion to baseline during a 3-month withdrawal period that occurred between a 6-month and a 9-month IVIg dosing period.
-
-
-
-
56
-
-
69249149090
-
Cognitive and functional outcomes from a phase II trial of bapineuzumab in mild to moderate Alzheimer's disease
-
WA, USA ():Abs
-
Salloway S SR, Gregg K, Black R, Grundman M: Cognitive and functional outcomes from a phase II trial of bapineuzumab in mild to moderate Alzheimer's disease. American Academy of Neurology, Seattle, WA, USA (2009):Abs S32.002.
-
(2009)
American Academy of Neurology, Seattle
-
-
Salloway, S.S.1
Gregg, K.2
Black, R.3
Grundman, M.4
-
57
-
-
69249160466
-
Intravenous immunoglobulin increases brain glucose metabolism in Alzheimer disease
-
WA, USA ():Abs
-
Mosconi L, Asamiak B, Tsakanikas D, Shah K, Kreisl W, Synan M,Morim S, Tsui W, De Leon M, Vallabhajousla S, Goldsmith S et al: Intravenous immunoglobulin increases brain glucose metabolism in Alzheimer disease. American Academy of Neurology, Seattle, WA, USA (2008):Abs S51.003.
-
(2008)
American Academy of Neurology, Seattle
-
-
Mosconi, L.1
Asamiak, B.2
Tsakanikas, D.3
Shah, K.4
Kreisl, W.5
Synan, M.6
Morim, S.7
Tsui, W.8
De Leon, M.9
Vallabhajousla, S.10
Goldsmith, S.11
-
58
-
-
69249150272
-
O3-05-04: Intravenous immunoglobulin (IVIg) maintains cognition over 18 months in patients with Alzheimer's disease (AD)
-
Abs O3-05-04
-
Adamiak B, Monthe C, Bender H, Szabo P, Schiff R, Weksler ME, Relkin NR: O3-05-04: Intravenous immunoglobulin (IVIg) maintains cognition over 18 months in patients with Alzheimer's disease (AD). Alzheimer's and Dementia (2006) 2(3 Suppl 1):Abs O3-05-04.
-
(2006)
Alzheimer's and Dementia
, vol.2
, Issue.3 SUPPL. 1
-
-
Adamiak, B.1
Monthe, C.2
Bender, H.3
Szabo, P.4
Schiff, R.5
Weksler, M.E.6
Relkin, N.R.7
-
59
-
-
69249142076
-
-
A multicentre, randomised, double blind, placebo controlled, multiple ascending dose, safety, tolerability, and amyloidimaging positron emission tomography (PET) trial of AAB 001 (ELN115727) in patients with mild to moderate Alzheimer's disease (AD): Current Controlled Trials Ltd, London, UK (2009). controlled-trials.com/ISRCTN17517446
-
A multicentre, randomised, double blind, placebo controlled, multiple ascending dose, safety, tolerability, and amyloidimaging positron emission tomography (PET) trial of AAB 001 (ELN115727) in patients with mild to moderate Alzheimer's disease (AD): Current Controlled Trials Ltd, London, UK (2009). controlled-trials.com/ISRCTN17517446
-
-
-
-
60
-
-
18144415471
-
Effects of Aβ immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease
-
Fox NC, Black RS, Gilman S, Rossor MN, Griffith SG, Jenkins L, Koller M: Effects of Aβ immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease. Neurology (2005) 64(9):1563-1572.
-
(2005)
Neurology
, vol.64
, Issue.9
, pp. 1563-1572
-
-
Fox, N.C.1
Black, R.S.2
Gilman, S.3
Rossor, M.N.4
Griffith, S.G.5
Jenkins, L.6
Koller, M.7
-
61
-
-
69249120453
-
Effect of bapineuzumab on MRI measures of cerebral volume change in patients with Alzheimer's disease
-
WA, USA ():Abs
-
Fox NC, DeCarli C, Black R, Grundman M: Effect of bapineuzumab on MRI measures of cerebral volume change in patients with Alzheimer's disease. American Academy of Neurology, Seattle, WA, USA (2009):Abs P03.098.
-
(2009)
American Academy of Neurology, Seattle
-
-
Fox, N.C.1
DeCarli, C.2
Black, R.3
Grundman, M.4
-
62
-
-
58149129243
-
Consequence of Aβ immunization on the vasculature of human Alzheimer's disease brain
-
Boche D, Zotova E, Weller RO, Love S, Neal JW, Pickering RM, Wilkinson D, Holmes C, Nicoll JA: Consequence of Aβ immunization on the vasculature of human Alzheimer's disease brain. Brain (2008) 131(Pt 12):3299-3310.
-
(2008)
Brain
, vol.131
, Issue.PART 12
, pp. 3299-3310
-
-
Boche, D.1
Zotova, E.2
Weller, R.O.3
Love, S.4
Neal, J.W.5
Pickering, R.M.6
Wilkinson, D.7
Holmes, C.8
Nicoll, J.A.9
-
63
-
-
70349847734
-
Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances
-
doi:10.1016/j.neurobiolaging.2008.01.017
-
Thal DR, Capetillo-Zarate E, Larionov S, Staufenbiel M, Zurbruegg S, Beckmann N: Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances. Neurobiol Aging (2008):doi:10.1016/j.neurobiolaging.2008.01.017.
-
(2008)
Neurobiol Aging
-
-
Thal, D.R.1
Capetillo-Zarate, E.2
Larionov, S.3
Staufenbiel, M.4
Zurbruegg, S.5
Beckmann, N.6
-
64
-
-
51349166667
-
-
2O PET imaging, respectively, and were demonstrated to be inversely correlated in various (though not all) brain regions.
-
2O PET imaging, respectively, and were demonstrated to be inversely correlated in various (though not all) brain regions.
-
-
-
-
65
-
-
0037703255
-
-
Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H et al: RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain. Nat Med (2003) 9(7):907-913. * Describes the interaction of Aβ with the receptor for advanced glycation endproducts (RAGE) at the BBB in transgenic mice, resulting in the transport of Aβ into the CNS and an associated proinflammatory response, thus outlining a possible target for modulating AD pathology.
-
Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H et al: RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain. Nat Med (2003) 9(7):907-913. * Describes the interaction of Aβ with the receptor for advanced glycation endproducts (RAGE) at the BBB in transgenic mice, resulting in the transport of Aβ into the CNS and an associated proinflammatory response, thus outlining a possible target for modulating AD pathology.
-
-
-
-
66
-
-
41249097238
-
Cerebral cortical arteriolar angiopathy, vascular β-amyloid, smooth muscle actin, Braak stage, and APOE genotype
-
Stopa EG, Butala P, Salloway S, Johanson CE, Gonzalez L, Tavares R, Hovanesian V, Hulette CM, Vitek MP, Cohen RA: Cerebral cortical arteriolar angiopathy, vascular β-amyloid, smooth muscle actin, Braak stage, and APOE genotype. Stroke (2008) 39(3): 814-821.
-
(2008)
Stroke
, vol.39
, Issue.3
, pp. 814-821
-
-
Stopa, E.G.1
Butala, P.2
Salloway, S.3
Johanson, C.E.4
Gonzalez, L.5
Tavares, R.6
Hovanesian, V.7
Hulette, C.M.8
Vitek, M.P.9
Cohen, R.A.10
-
67
-
-
0035047718
-
Cerebral microvascular pathology in aging and Alzheimer's disease
-
Farkas E, Luiten PG: Cerebral microvascular pathology in aging and Alzheimer's disease. Prog Neurobiol (2001) 64(6):575-611.
-
(2001)
Prog Neurobiol
, vol.64
, Issue.6
, pp. 575-611
-
-
Farkas, E.1
Luiten, P.G.2
-
68
-
-
33748925716
-
Interventions for heart disease and their effects on Alzheimer's disease
-
Wolozin B, Bednar MM: Interventions for heart disease and their effects on Alzheimer's disease. Neurol Res (2006) 28(6): 630-636.
-
(2006)
Neurol Res
, vol.28
, Issue.6
, pp. 630-636
-
-
Wolozin, B.1
Bednar, M.M.2
-
69
-
-
69249154058
-
Risk factors and clinical course associated with vasogenic edema in a phase II trial of bapineuzumab
-
WA, USA ():Abs
-
Sperling RA, Salloway S, Fox NC, Barackos J, Morris K, Francis G, Black RS, Grundman M: Risk factors and clinical course associated with vasogenic edema in a phase II trial of bapineuzumab. American Academy of Neurology, Seattle, WA, USA (2009):Abs S32.001
-
(2009)
American Academy of Neurology, Seattle
-
-
Sperling, R.A.1
Salloway, S.2
Fox, N.C.3
Barackos, J.4
Morris, K.5
Francis, G.6
Black, R.S.7
Grundman, M.8
-
70
-
-
54349124928
-
O4-03-04: Safety assessments and biomarker changes following a monoclonal Aβ antibody given to subjects with Alzheimer's disease
-
Abs O4-03-04
-
Siemers ER, Benson C, Gonzales C, Hansen R, Dean RA, Farlow MR, DeMattos R: O4-03-04: Safety assessments and biomarker changes following a monoclonal Aβ antibody given to subjects with Alzheimer's disease. Alzheimer's and Dementia (2006) 2(3 Suppl 1):Abs O4-03-04.
-
(2006)
Alzheimer's and Dementia
, vol.2
, Issue.3 SUPPL. 1
-
-
Siemers, E.R.1
Benson, C.2
Gonzales, C.3
Hansen, R.4
Dean, R.A.5
Farlow, M.R.6
DeMattos, R.7
-
71
-
-
48949085739
-
Amyloid-β immunisation for Alzheimer's disease
-
Wisniewski T, Konietzko U: Amyloid-β immunisation for Alzheimer's disease. Lancet Neurol (2008) 7(9):805-811.
-
(2008)
Lancet Neurol
, vol.7
, Issue.9
, pp. 805-811
-
-
Wisniewski, T.1
Konietzko, U.2
-
72
-
-
0033835996
-
Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F, Cannon C, Barbour R, Burke RL, Games D, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K et al: Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med (2000) 6(8): 916-919.
-
(2000)
Nat Med
, vol.6
, Issue.8
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
Khan, K.11
-
73
-
-
3042839092
-
Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition
-
Wilcock DM, Rojiani A, Rosenthal A, Levkowitz G, Subbarao S, Alamed J, Wilson D, Wilson N, Freeman MJ, Gordon MN, Morgan D: Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition. J Neurosci (2004) 24(27):6144-6151.
-
(2004)
J Neurosci
, vol.24
, Issue.27
, pp. 6144-6151
-
-
Wilcock, D.M.1
Rojiani, A.2
Rosenthal, A.3
Levkowitz, G.4
Subbarao, S.5
Alamed, J.6
Wilson, D.7
Wilson, N.8
Freeman, M.J.9
Gordon, M.N.10
Morgan, D.11
-
74
-
-
0035877075
-
Antibody-mediated phagocytosis of the amyloid β-peptide in microglia is differentially modulated by C1q
-
Webster SD, Galvan MD, Ferran E, Garzon-Rodriguez W, Glabe CG, Tenner AJ: Antibody-mediated phagocytosis of the amyloid β-peptide in microglia is differentially modulated by C1q. J Immunol (2001) 166(12):7496-7503.
-
(2001)
J Immunol
, vol.166
, Issue.12
, pp. 7496-7503
-
-
Webster, S.D.1
Galvan, M.D.2
Ferran, E.3
Garzon-Rodriguez, W.4
Glabe, C.G.5
Tenner, A.J.6
-
75
-
-
59249103997
-
Alzheimer disease macrophages shuttle amyloid-β from neurons to vessels, contributing to amyloid angiopathy
-
Zaghi J, Goldenson B, Inayathullah M, Lossinsky AS, Masoumi A, Avagyan H, Mahanian M, Bernas M, Weinand M, Rosenthal MJ, Espinosa-Jeffrey A et al: Alzheimer disease macrophages shuttle amyloid-β from neurons to vessels, contributing to amyloid angiopathy. Acta Neuropathol (2009) 117(2):111-124.
-
(2009)
Acta Neuropathol
, vol.117
, Issue.2
, pp. 111-124
-
-
Zaghi, J.1
Goldenson, B.2
Inayathullah, M.3
Lossinsky, A.S.4
Masoumi, A.5
Avagyan, H.6
Mahanian, M.7
Bernas, M.8
Weinand, M.9
Rosenthal, M.J.10
Espinosa-Jeffrey, A.11
-
76
-
-
47949132196
-
Active and passive immunotherapy for neurodegenerative disorders
-
Brody DL, Holtzman DM: Active and passive immunotherapy for neurodegenerative disorders. Annu Rev Neurosci (2008) 31:175-193.
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 175-193
-
-
Brody, D.L.1
Holtzman, D.M.2
-
77
-
-
30844472909
-
IgG-assisted age-dependent clearance of Alzheimer's amyloid β peptide by the blood-brain barrier neonatal Fc receptor
-
Describes neonatal Fc receptor-mediated transport of amyloid across the BBB; details of this process are relevant to understanding the equilibrium established for amyloid between central and peripheral compartments, *
-
Deane R, Sagare A, Hamm K, Parisi M, LaRue B, Guo H, Wu Z, Holtzman DM, Zlokovic BV: IgG-assisted age-dependent clearance of Alzheimer's amyloid β peptide by the blood-brain barrier neonatal Fc receptor. J Neurosci (2005) 25(50):11495-11503. * Describes neonatal Fc receptor-mediated transport of amyloid across the BBB; details of this process are relevant to understanding the equilibrium established for amyloid between central and peripheral compartments.
-
(2005)
J Neurosci
, vol.25
, Issue.50
, pp. 11495-11503
-
-
Deane, R.1
Sagare, A.2
Hamm, K.3
Parisi, M.4
LaRue, B.5
Guo, H.6
Wu, Z.7
Holtzman, D.M.8
Zlokovic, B.V.9
-
78
-
-
4043167747
-
Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
-
Oddo S, Billings L, Kesslak JP, Cribbs DH, LaFerla FM: Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron (2004) 43(3):321-332.
-
(2004)
Neuron
, vol.43
, Issue.3
, pp. 321-332
-
-
Oddo, S.1
Billings, L.2
Kesslak, J.P.3
Cribbs, D.H.4
LaFerla, F.M.5
-
79
-
-
69249123594
-
-
Weller RO: CSF, interstitial fluid, cerebrovascular disease and Alzheimer's disease. The 4th International Congress of the International Society for Vascular Behavioral and Cognitive Disorders (VAS-COG), City of Singapore, Singapore (2009).
-
Weller RO: CSF, interstitial fluid, cerebrovascular disease and Alzheimer's disease. The 4th International Congress of the International Society for Vascular Behavioral and Cognitive Disorders (VAS-COG), City of Singapore, Singapore (2009).
-
-
-
-
80
-
-
50949094660
-
A single ascending dose study of bapineuzumab, a humanized monoclonal antibody to Aβ, in AD
-
IL, USA
-
Black RS, Sperling R, Kirby L, Safirstein B, Motter R, Pallay A, Nichols A, Grundman M: A single ascending dose study of bapineuzumab, a humanized monoclonal antibody to Aβ, in AD. International Geneva/Springfield Symposium on Advances in Alzheimer Therapy, Geneva, Switzerland/Springfield, IL, USA (2006).
-
(2006)
International Geneva/Springfield Symposium on Advances in Alzheimer Therapy, Geneva, Switzerland/Springfield
-
-
Black, R.S.1
Sperling, R.2
Kirby, L.3
Safirstein, B.4
Motter, R.5
Pallay, A.6
Nichols, A.7
Grundman, M.8
-
81
-
-
67649268898
-
P4-351: Effects of uninterrrupted intravenous immunoglobulin treatment of Alzheimer's disease for nine months
-
Abs P4-351
-
Tsakanikas D, Shah K, Flores C, Assuras S, Relkin NR: P4-351: Effects of uninterrrupted intravenous immunoglobulin treatment of Alzheimer's disease for nine months. Alzheimer's and Dementia (2008) 4(4 Suppl 1):Abs P4-351.
-
(2008)
Alzheimer's and Dementia
, vol.4
, Issue.4 SUPPL. 1
-
-
Tsakanikas, D.1
Shah, K.2
Flores, C.3
Assuras, S.4
Relkin, N.R.5
|