MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation

Journal of Immunology

Volumn 183, Issue 1, 2009, Pages 261-269

  O'Reilly, Lorraine A ^a   Kruse, Elizabeth A ^a,b   Puthalakath, Hamsa ^a,c   Kelly, Priscilla N ^a   Kaufmann, Thomas ^a,d   Huang, David C S ^a   Strasser, Andreas ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; IONOMYCIN; ISOPROTEIN; LAMBDA PHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; DRUG DERIVATIVE; IMMUNOGLOBULIN F(AB) FRAGMENT; MEMBRANE PROTEIN; MITOGENIC AGENT; ONCOPROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOLOL MYRISTATE ACETATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CELL KILLING; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MITOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY; RAT; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE; WISTAR RAT;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; B-LYMPHOCYTE SUBSETS; CELL SURVIVAL; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; IMMUNOGLOBULIN FAB FRAGMENTS; IONOMYCIN; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; MITOGENS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; RATS; RATS, WISTAR; T-LYMPHOCYTE SUBSETS; TETRADECANOYLPHORBOL ACETATE;

EID: 68949094024     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803853     Document Type: Article

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