Transient in vivo β-globin production after lentiviral gene transfer to hematopoietic stem cells in the nonhuman primate

Human Gene Therapy

Volumn 20, Issue 6, 2009, Pages 563-572

  Hayakawa, Jun ^a   Ueda, Takahiro ^a   Lisowski, Leszek ^a   Hsieh, Matthew M ^a   Washington, Kareem ^a   Phang, Oswald ^a   Metzger, Mark ^a   Krouse, Allen ^a   Donahue, Robert E ^a   Sadelain, Michel ^a   Tisdale, John F ^a,b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; CD34 ANTIGEN; GENOMIC DNA; HEMOGLOBIN; IMMUNOGLOBULIN M ANTIBODY; LENTIVIRUS VECTOR; LENTIVIRUS VECTOR TNS 9 3; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT HUMAN STEM CELL FACTOR; STEM CELL FACTOR; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BETA GLOBIN GENE; CD34 SELECTION; CELL DIFFERENTIATION; COLONY FORMING UNIT; CONTROLLED STUDY; ERYTHROID CELL; FEMALE; FLOW CYTOMETRY; GLOBIN GENE; GLOBIN SYNTHESIS; GRANULOCYTE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INTRAVENOUS ADMINISTRATION; MACACA; MASS SPECTROMETRY; MONONUCLEAR CELL; NONHUMAN; PERIPHERAL LYMPHOCYTE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SICKLE CELL BETA THALASSEMIA; SOUTHERN BLOTTING; THERAPY EFFECT; VESICULAR STOMATITIS VIRUS; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; WHOLE BODY RADIATION; ADULT; ANIMAL; BIOSYNTHESIS; CELL COUNT; CLONOGENIC ASSAY; GENE TRANSFER; GENETIC TRANSDUCTION; GENETICS; HEMATOPOIETIC STEM CELL; LENTIVIRINAE; METABOLISM; TIME;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA; PRIMATES; VESICULAR STOMATITIS VIRUS;

ADULT; ANIMALS; ANTIGENS, CD34; BETA-GLOBINS; BLOTTING, SOUTHERN; CELL COUNT; COLONY-FORMING UNITS ASSAY; FLOW CYTOMETRY; GENE TRANSFER TECHNIQUES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; LENTIVIRUS; MACACA MULATTA; TIME FACTORS; TRANSDUCTION, GENETIC;

EID: 68849108689     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2008.186     Document Type: Article

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