메뉴 건너뛰기




Volumn 92, Issue 4, 1998, Pages 1131-1141

Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; DNA; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 6; STEM CELL FACTOR;

EID: 0032529523     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.4.1131.416k41_1131_1141     Document Type: Article
Times cited : (230)

References (48)
  • 1
    • 0029857382 scopus 로고    scopus 로고
    • Gene marking and gene therapy directed at primary hematopoietic cells
    • Dunbar CE, Young NS: Gene marking and gene therapy directed at primary hematopoietic cells. Curr Opin Hematol 3:430, 1996
    • (1996) Curr Opin Hematol , vol.3 , pp. 430
    • Dunbar, C.E.1    Young, N.S.2
  • 2
    • 0030034183 scopus 로고    scopus 로고
    • Rapid and efficient selection of human hematopoietic cells expressing murine heat-stable antigen as an indicator of retroviral-mediated gene transfer
    • Conneally E, Bardy P, Eaves CJ, Thomas T, Chappel S, Shpall EJ, Humphries RK: Rapid and efficient selection of human hematopoietic cells expressing murine heat-stable antigen as an indicator of retroviral-mediated gene transfer. Blood 87:456, 1996
    • (1996) Blood , vol.87 , pp. 456
    • Conneally, E.1    Bardy, P.2    Eaves, C.J.3    Thomas, T.4    Chappel, S.5    Shpall, E.J.6    Humphries, R.K.7
  • 4
    • 0028143406 scopus 로고
    • Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer
    • Pawliuk R, Kay R, Lansdorp P, Humphries RK: Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer. Blood 84:2868, 1994
    • (1994) Blood , vol.84 , pp. 2868
    • Pawliuk, R.1    Kay, R.2    Lansdorp, P.3    Humphries, R.K.4
  • 5
    • 0030669120 scopus 로고    scopus 로고
    • Sustained high-level reconstitution of the hematopoietic system by preselected hematopoeitic cells expressing a transduced cell-surface antigen
    • Pawliuk R, Eaves CJ, Humphries RK: Sustained high-level reconstitution of the hematopoietic system by preselected hematopoeitic cells expressing a transduced cell-surface antigen. Hum Gene Ther 8:1595, 1997
    • (1997) Hum Gene Ther , vol.8 , pp. 1595
    • Pawliuk, R.1    Eaves, C.J.2    Humphries, R.K.3
  • 6
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller DG, Adam MA, Miller AD: Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol 10:4239, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 4239
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 7
    • 0029981525 scopus 로고    scopus 로고
    • Ex vivo expansion of hematopoietic precursors, progenitors, and stem cells: The next generation of cellular therapeutics
    • Emerson SG: Ex vivo expansion of hematopoietic precursors, progenitors, and stem cells: The next generation of cellular therapeutics. Blood 87:3082, 1996
    • (1996) Blood , vol.87 , pp. 3082
    • Emerson, S.G.1
  • 8
    • 0027233837 scopus 로고
    • Ex-vivo expansion of hematopoietic stem and progenitor cells-Robbing Peter to pay Paul?
    • Williams DA: Ex-vivo expansion of hematopoietic stem and progenitor cells-Robbing Peter to pay Paul? Blood 81:3169, 1993
    • (1993) Blood , vol.81 , pp. 3169
    • Williams, D.A.1
  • 9
    • 0029858420 scopus 로고    scopus 로고
    • Partially differentiated ex vivo expanded cells accelerate hematologic recovery in myeloablated mice transplanted with highly enriched long-term repopulating stem cells
    • Szilvassy SJ, Weller KP, Chen B, Juttner CA, Tsukamoto A, Hoffman R: Partially differentiated ex vivo expanded cells accelerate hematologic recovery in myeloablated mice transplanted with highly enriched long-term repopulating stem cells. Blood 88:3642, 1996
    • (1996) Blood , vol.88 , pp. 3642
    • Szilvassy, S.J.1    Weller, K.P.2    Chen, B.3    Juttner, C.A.4    Tsukamoto, A.5    Hoffman, R.6
  • 10
    • 0027178453 scopus 로고
    • Bone marrow tranplant with IL-1 plus kit ligand ex vivo-expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell lineage and proliferative potential
    • Muench MO, Firpo MT, Moore MA: Bone marrow tranplant with IL-1 plus kit ligand ex vivo-expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell lineage and proliferative potential. Blood 81:3463, 1993
    • (1993) Blood , vol.81 , pp. 3463
    • Muench, M.O.1    Firpo, M.T.2    Moore, M.A.3
  • 11
    • 0029016628 scopus 로고
    • Murine marrow cells expanded in culture with IL-3, IL-6, IL-11, and SCF acquire an engraftment defect in normal hosts
    • Peters SO, Kittler ELW, Ramshaw HS, Quesenberry PJ: Murine marrow cells expanded in culture with IL-3, IL-6, IL-11, and SCF acquire an engraftment defect in normal hosts. Exp Hematol 23:461, 1995
    • (1995) Exp Hematol , vol.23 , pp. 461
    • Peters, S.O.1    Kittler, E.L.W.2    Ramshaw, H.S.3    Quesenberry, P.J.4
  • 12
    • 0031936092 scopus 로고    scopus 로고
    • Restrictions in the stem cell function of murine bone marrow grafts after ex vivo expansion of short-term repopulating progenitors
    • Varas F, Bernad A, Eueren JA: Restrictions in the stem cell function of murine bone marrow grafts after ex vivo expansion of short-term repopulating progenitors. Exp Hematol 26:100, 1998
    • (1998) Exp Hematol , vol.26 , pp. 100
    • Varas, F.1    Bernad, A.2    Eueren, J.A.3
  • 13
    • 0026758506 scopus 로고
    • Retroviral vector-mediated gene transfer into primitive human hematopoietic progentior cells: Effects of mast cell growth factor (MGF) combined with other cytokines
    • Nolta JA, Crooks GM, Overell RW, Williams DE, Kohn DB: Retroviral vector-mediated gene transfer into primitive human hematopoietic progentior cells: Effects of mast cell growth factor (MGF) combined with other cytokines. Exp Hematol 20:1065, 1992
    • (1992) Exp Hematol , vol.20 , pp. 1065
    • Nolta, J.A.1    Crooks, G.M.2    Overell, R.W.3    Williams, D.E.4    Kohn, D.B.5
  • 14
    • 0026699602 scopus 로고
    • Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage
    • Haylock DN, To LB, Dowse TL, Juttner CA, Simmons PJ: Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage. Blood 80:1405, 1992
    • (1992) Blood , vol.80 , pp. 1405
    • Haylock, D.N.1    To, L.B.2    Dowse, T.L.3    Juttner, C.A.4    Simmons, P.J.5
  • 15
    • 0027162426 scopus 로고
    • Large-scales expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures
    • Koller MR, Emerson SG, Palsson BO: Large-scales expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures. Blood 82:378, 1993
    • (1993) Blood , vol.82 , pp. 378
    • Koller, M.R.1    Emerson, S.G.2    Palsson, B.O.3
  • 16
    • 0029977501 scopus 로고    scopus 로고
    • Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: Novel responses to Flt3-ligand and thrombopoietin
    • Petzer AL, Zandstra PW, Piret JM, Eaves CJ: Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: Novel responses to Flt3-ligand and thrombopoietin. J Exp Med 183:2551, 1996
    • (1996) J Exp Med , vol.183 , pp. 2551
    • Petzer, A.L.1    Zandstra, P.W.2    Piret, J.M.3    Eaves, C.J.4
  • 18
    • 0029047564 scopus 로고
    • Reconstitution of hematopoiesis after high-dose chemotherapy by autologous progenitor cells generated ex vivo
    • Brugger W, Heimfeld S, Berenson RJ, Mertelsmann R, Kanz L: Reconstitution of hematopoiesis after high-dose chemotherapy by autologous progenitor cells generated ex vivo. N Engl J Med 333:283, 1995
    • (1995) N Engl J Med , vol.333 , pp. 283
    • Brugger, W.1    Heimfeld, S.2    Berenson, R.J.3    Mertelsmann, R.4    Kanz, L.5
  • 20
    • 0030063293 scopus 로고    scopus 로고
    • Peripheral blood CD34+ cells differ from bone marrow CD34+ cells in Thy-1 expression and cell cycle status in nonhuman primates mobilized or non mobilized with granulocyte colony-stimulating factor and/or stem cell factor
    • Donahue RE, Kirby MR, Metzger ME, Agricola BA, Sellers SE, Cullis HM: Peripheral blood CD34+ cells differ from bone marrow CD34+ cells in Thy-1 expression and cell cycle status in nonhuman primates mobilized or non mobilized with granulocyte colony-stimulating factor and/or stem cell factor. Blood 87:1644, 1996
    • (1996) Blood , vol.87 , pp. 1644
    • Donahue, R.E.1    Kirby, M.R.2    Metzger, M.E.3    Agricola, B.A.4    Sellers, S.E.5    Cullis, H.M.6
  • 21
    • 0027819175 scopus 로고
    • Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells
    • Cassel A, Cottier-Fox M, Doren S, Dunbar CE: Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells. Exp Hematol 21:585, 1993
    • (1993) Exp Hematol , vol.21 , pp. 585
    • Cassel, A.1    Cottier-Fox, M.2    Doren, S.3    Dunbar, C.E.4
  • 24
    • 0023392425 scopus 로고
    • Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model
    • Nienhuis AW, Donahue RE. Karlsson S, Clark SC, Agricola B, Antinoff N, Pierce JE, Turner P, Anderson WF: Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. J Clin Invest 80:573, 1987
    • (1987) J Clin Invest , vol.80 , pp. 573
    • Nienhuis, A.W.1    Donahue, R.E.2    Karlsson, S.3    Clark, S.C.4    Agricola, B.5    Antinoff, N.6    Pierce, J.E.7    Turner, P.8    Anderson, W.F.9
  • 26
    • 0029859412 scopus 로고    scopus 로고
    • Improved retroviral gene transfer into murine and rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor
    • Dunbar CE, Seidel NE, Doren S, Sellers S, Cline AP, Metzger ME, Agricola BA, Donahue RE, Bodine DM: Improved retroviral gene transfer into murine and rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor. Proc Natl Acad Sci USA 93:11871, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11871
    • Dunbar, C.E.1    Seidel, N.E.2    Doren, S.3    Sellers, S.4    Cline, A.P.5    Metzger, M.E.6    Agricola, B.A.7    Donahue, R.E.8    Bodine, D.M.9
  • 28
    • 0030005639 scopus 로고    scopus 로고
    • Flt3 ligand induces proliferation of quiescent human bone marrow CD34+CD38- cells and maintains progenitor cells in vitro
    • Shah AJ, Smogorzweska EM, Hannum C, Crooks GM: Flt3 ligand induces proliferation of quiescent human bone marrow CD34+CD38- cells and maintains progenitor cells in vitro. Blood 87:3563, 1996
    • (1996) Blood , vol.87 , pp. 3563
    • Shah, A.J.1    Smogorzweska, E.M.2    Hannum, C.3    Crooks, G.M.4
  • 29
    • 0030059543 scopus 로고    scopus 로고
    • The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor cells in vitro
    • Rusten LS, Lyman SD, Veiby OP, Jacobsen SEW: The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor cells in vitro. Blood 87:1317, 1996
    • (1996) Blood , vol.87 , pp. 1317
    • Rusten, L.S.1    Lyman, S.D.2    Veiby, O.P.3    Jacobsen, S.E.W.4
  • 30
    • 0030899608 scopus 로고    scopus 로고
    • In vitro expansion of hematopoietic progenitors and maintenance of stem cells: Comparison between FLT3/FLK-2 ligand and KIT ligand
    • Yonemura Y, Ku H, Lyman SD, Ogawa M: In vitro expansion of hematopoietic progenitors and maintenance of stem cells: Comparison between FLT3/FLK-2 ligand and KIT ligand. Blood 89:1915, 1997
    • (1997) Blood , vol.89 , pp. 1915
    • Yonemura, Y.1    Ku, H.2    Lyman, S.D.3    Ogawa, M.4
  • 32
    • 0029838238 scopus 로고    scopus 로고
    • Gene transfer into hematopoietic stem cells of nonhuman primates
    • Van Beusechem VW, Valerio D: Gene transfer into hematopoietic stem cells of nonhuman primates. Hum Gene Ther 7:1649, 1996
    • (1996) Hum Gene Ther , vol.7 , pp. 1649
    • Van Beusechem, V.W.1    Valerio, D.2
  • 33
    • 0030997671 scopus 로고    scopus 로고
    • Does the granulocytemacrophage colony-forming unit content in ex vivo-expanded grafts predict the recovery of the recipient leukocytes?
    • Albella B, Segovia JC, Eueren JA: Does the granulocytemacrophage colony-forming unit content in ex vivo-expanded grafts predict the recovery of the recipient leukocytes? Blood 90:464, 1997
    • (1997) Blood , vol.90 , pp. 464
    • Albella, B.1    Segovia, J.C.2    Eueren, J.A.3
  • 35
    • 0028282857 scopus 로고
    • Patient characteristics associated with successful mobilizing and autografting of peripheral blood progenitor cells in malignant lymphoma
    • Haas R, Möhle R, Frühauf S, Goldschmidt H, Witt B, Flentje M, Wannenmacher M, Hunstein W: Patient characteristics associated with successful mobilizing and autografting of peripheral blood progenitor cells in malignant lymphoma. Blood 83:3787, 1994
    • (1994) Blood , vol.83 , pp. 3787
    • Haas, R.1    Möhle, R.2    Frühauf, S.3    Goldschmidt, H.4    Witt, B.5    Flentje, M.6    Wannenmacher, M.7    Hunstein, W.8
  • 36
    • 0028963248 scopus 로고
    • Peripheral blood stem cell transplants for multiple myeloma: Identification of favorable variables for rapid engraftment in 225 patients
    • Tricot G, Jagannath S, Vesole D, Nelson J, Tindle S, Miller L, Cheson B, Crowley J, Barlogie B: Peripheral blood stem cell transplants for multiple myeloma: Identification of favorable variables for rapid engraftment in 225 patients. Blood 85:588, 1995
    • (1995) Blood , vol.85 , pp. 588
    • Tricot, G.1    Jagannath, S.2    Vesole, D.3    Nelson, J.4    Tindle, S.5    Miller, L.6    Cheson, B.7    Crowley, J.8    Barlogie, B.9
  • 37
    • 0029135329 scopus 로고
    • Engraftment of bone marrow cells into normal unprepared hosts: Effects of 5-fluorouracil and cell cycle status
    • Ramshaw HS, Rao SS, Crittenden RB, Peters SO, Weier HU, Quesenberry PJ: Engraftment of bone marrow cells into normal unprepared hosts: Effects of 5-fluorouracil and cell cycle status. Blood 86:924, 1995
    • (1995) Blood , vol.86 , pp. 924
    • Ramshaw, H.S.1    Rao, S.S.2    Crittenden, R.B.3    Peters, S.O.4    Weier, H.U.5    Quesenberry, P.J.6
  • 38
    • 0029767842 scopus 로고    scopus 로고
    • The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction
    • Orlic D, Girard LJ, Jordan CT, Anderson SM, Cline AP. Bodine DM: The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction. Proc Natl Acad Sci USA 93:11097, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11097
    • Orlic, D.1    Girard, L.J.2    Jordan, C.T.3    Anderson, S.M.4    Cline, A.P.5    Bodine, D.M.6
  • 40
    • 0030886656 scopus 로고    scopus 로고
    • Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice
    • Conneally E, Cashman J, Petzer A, Eaves C: Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice. Proc Natl Acad Sci USA 94:9836, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9836
    • Conneally, E.1    Cashman, J.2    Petzer, A.3    Eaves, C.4
  • 41
    • 0030916733 scopus 로고    scopus 로고
    • Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo seid-repopulating cell assay
    • Wang JCY, Doedens M, Dick JE: Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo seid-repopulating cell assay. Blood 89:3919, 1997
    • (1997) Blood , vol.89 , pp. 3919
    • Wang, J.C.Y.1    Doedens, M.2    Dick, J.E.3
  • 43
    • 0031468286 scopus 로고    scopus 로고
    • Placental and/or umbilical cord blood: An alternative source of hematopoietic stem cells for transplantation
    • Cairo MS, Wagner JE: Placental and/or umbilical cord blood: An alternative source of hematopoietic stem cells for transplantation. Blood 90:4665, 1997
    • (1997) Blood , vol.90 , pp. 4665
    • Cairo, M.S.1    Wagner, J.E.2
  • 44
    • 0031008521 scopus 로고    scopus 로고
    • In vitro maintenance of highly purified transplantable hematopoietic stem cells
    • Moore KA, Ema H, Lemischka IR: In vitro maintenance of highly purified transplantable hematopoietic stem cells. Blood 89:4337, 1997
    • (1997) Blood , vol.89 , pp. 4337
    • Moore, K.A.1    Ema, H.2    Lemischka, I.R.3
  • 45
    • 9044237272 scopus 로고    scopus 로고
    • Maintenance of murine long-term repopulating stem cells in ex vivo culture is affected by modulation of transforming growth factor-β but not macrophage inflammatory protein-lα activities
    • Soma T, Yu JM, Dunbar CE: Maintenance of murine long-term repopulating stem cells in ex vivo culture is affected by modulation of transforming growth factor-β but not macrophage inflammatory protein-lα activities. Blood 87:4561, 1996
    • (1996) Blood , vol.87 , pp. 4561
    • Soma, T.1    Yu, J.M.2    Dunbar, C.E.3
  • 46
    • 0030823542 scopus 로고    scopus 로고
    • Ability of early acting cytokines to directly promote survival and suppress apoptosis of human primitive CD34+CD38- bone marrow cells with multilineage potential at the single cell level: Key role of thrombopoietin
    • Borge OJ, Ramsfjell V, Cui L, Jacobsen SEW: Ability of early acting cytokines to directly promote survival and suppress apoptosis of human primitive CD34+CD38- bone marrow cells with multilineage potential at the single cell level: Key role of thrombopoietin. Blood 90:2282, 1997
    • (1997) Blood , vol.90 , pp. 2282
    • Borge, O.J.1    Ramsfjell, V.2    Cui, L.3    Jacobsen, S.E.W.4
  • 47
    • 0031157028 scopus 로고    scopus 로고
    • Thrombopoietin directly and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+ CD38-) human bone marrow progenitor cells: Distinct and key interactions with the ligands for c-kit and flt3, and inhibitory effects of TGF-beta and TNF-alpha
    • Ramsfjell V, Borge OJ, Cui L, Jacobsen SE: Thrombopoietin directly and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+ CD38-) human bone marrow progenitor cells: Distinct and key interactions with the ligands for c-kit and flt3, and inhibitory effects of TGF-beta and TNF-alpha. J Immunol 158:5169, 1997
    • (1997) J Immunol , vol.158 , pp. 5169
    • Ramsfjell, V.1    Borge, O.J.2    Cui, L.3    Jacobsen, S.E.4
  • 48
    • 0030788152 scopus 로고    scopus 로고
    • Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture
    • Bhatia M, Bonnet D, Kapp U, Wang JC, Murdoch B, Dick JE: Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture. J Exp Med 18:619, 1997
    • (1997) J Exp Med , vol.18 , pp. 619
    • Bhatia, M.1    Bonnet, D.2    Kapp, U.3    Wang, J.C.4    Murdoch, B.5    Dick, J.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.