Improved gene transfer into baboon marrow repopulating cells using recombinant human fibronectin fragment CH-296 in combination with interleukin-6, stem cell factor, FLT-3 ligand, and megakaryocyte growth and development factor

Blood

Volumn 92, Issue 6, 1998, Pages 1878-1886

  Kiem, Hans Peter ^a   Andrews, Robert G ^b   Morris, Julia ^b   Peterson, Laura ^b   Heyward, Scott ^b   Allen, James M ^b   Rasko, John E J ^b   Potter, Jennifer ^b   Miller, A Dusty ^b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE PLACENTA ISOENZYME; BOVINE SERUM ALBUMIN; CD34 ANTIGEN; FIBRONECTIN; GROWTH FACTOR; INTERLEUKIN 6; MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT STEM CELL FACTOR; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BABOON; CONTROLLED STUDY; GENE TRANSFER; GIBBON LEUKEMIA VIRUS; HEMATOPOIETIC STEM CELL; NONHUMAN; PRIORITY JOURNAL;

EID: 0032531012     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.6.1878     Document Type: Article

References (35)

1. Kohn DB: The current status of gene therapy using hematopoietic stem cells. Curr Opin Pediatr 7:56, 1995
2. Karlsson S: Treatment of genetic defects in hematopoietic cell function by gene transfer. Blood 78:2481, 1991
3. Kiem H-P, von Kalle C, Schuening F, Storb R: Gene therapy and bone marrow transplantation. Curr Opin Oncol 7:107, 1995
4. O'Marcaigh AS, Cowan MJ: Bone marrow transplantation for inherited diseases. Curr Opin Oncol 9:126, 1997
5. Kapelushnik J, Or R, Filon D, Nagler A, Cividalli G, Aker M, Naparstek E, Slavin S, Oppenheim A: Analysis of beta-globin mutations shows stable mixed chimerism in patients with thalassemia after bone marrow transplantation. Blood 86:3241, 1995
6. + progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviralmediated transduction. Blood 89:446, 1997
7. Nolta JA, Smogorzewska EM, Kohn DB: Analysis of optimal conditions for retroviral-mediated transduction of primitative human hematopoietic cells. Blood 86:101, 1995
8. Chuck AS, Clarke MF, Palsson BO: Retroviral infection is limited by Brownian motion. Hum Gene Ther 7:1527, 1996
9. Palsson B, Andreadis S: The physico-chemical factors that govern retrovirus-mediated gene transfer. Exp Hematol 25:94, 1997
10. Bahnson AB, Dunigan JT, Baysal BE, Mohney T, Atchison RW, Nimgaonkar MT, Ball ED, Barranger JA: Centrifugal enhancement of retroviral mediated gene transfer. J Virol Methods 54:131, 1995
11. Moritz T, Dutt P, Xiao X, Carstanjen D, Vik T, Hanenberg H, Williams DA: Fibronectin improves transduction of reconstituting hematopoietic stem cells by retroviral vectors: Evidence of direct viral binding to chymotryptic carboxy-terminal fragments. Blood 88:855, 1996
12. Hanenberg H, Xiao XL, Dilloo D, Hashino K, Kato I, Williams DA: Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells. Nat Med 2:876, 1996
13. Dunbar CE, Seidel NE, Doren S, Sellers S, Cline AP, Metzger ME, Agricola BA, Donahue RE, Bodine DM: Improved retroviral gene transfer into murine and rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor. Proc Natl Acad Sci USA 93:11871, 1996
14. Kiem H-P, Darovsky B, von Kalle C, Goehle S, Graham T, Miller AD, Storb R, Schuening FG: Long-term persistence of canine hematopoietic cells genetically marked by retrovirus vectors. Hum Gene Ther 7:89, 1996
15. Kiem H-P, Heyward S, Winkler A, Potter J, Allen JM, Miller AD, Andrews RG: Gene transfer into marrow repopulating cells: Comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons. Blood 90:4638, 1997
16. Van Beusechem VW, Valerio D: Gene transfer into hematopoietic stem cells of nonhuman primates. Hum Gene Ther 7:1649, 1996
17. Kohn DB, Weinberg KI, Nolta JA, Heiss LN, Lenarsky C, Crooks GM, Hanley ME, Annett G, Brooks JS, el-Khoureiy A, Lawrence K, Wells S, Moen RC, Bastian J, Williams-Herman DE, Elder M, Wara D, Bowen T, Hershfield MS, Mullen CA, Blaese RM, Parkman R: Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med 1:1017, 1995
18. Morton WR, Knitter GH, Smith PM, Susor TG, Schmitt K: Alternatives to chronic restraint of nonhuman primates. J Am Vet Med Assn 191:1282, 1987
19. Miller AD, Rosman GJ: Improved retroviral vectors for gene transfer and expression. Biotechniques 7:980, 1989
20. Miller AD, Garcia JV, von Suhr N, Lynch CM, Wilson C, Eiden MV: Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus. J Virol 65:2220, 1991
21. Miller DG, Edwards RH, Miller AD: Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus. Proc Natl Acad Sci USA 91:78, 1994
22. Kimizuka F, Taguchi Y, Ohdate Y, Kawase Y, Shimojo T, Hashino K, Kato I, Sekiguchi K, Titani K: Production and characterization of functional domains of human fibronectin expressed in Escherichia coli. J Biochem 110:284, 1991
23. Hanenberg H, Hashino K, Konishi H, Hock RA, Kato I, Williams DA: Optimization of fibronectin-assisted retroviral gene transfer into human CD34+ hematopoietic cells. Hum Gene Ther 8:2193, 1997
24. Andrews RG, Bryant EM, Bartelmez SH, Muirhead DY, Knitter GH, Bensinger W, Strong DM, Bernstein ID: CD34+ marrow cells, devoid of T and B lymphocytes, reconstitute stable lymphopoiesis and myelopoiesis in lethally irradiated allogeneic baboons. Blood 80:1693, 1992
25. Fields-Berry SC, Halliday AL, Cepko CL: A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina. Proc Natl Acad Sci USA 89:693, 1992
26. von Kalle C, Kiem H-P, Goehle S, Darovsky B, Heimfeld S, Torok-Storb B, Storb R, Schuening FG: Increased gene transfer into human hematopoietic progenitor cells by extended in vitro exposure to a pseudotyped retroviral vector. Blood 84:2890, 1994
27. Yonemura Y, Ku H, Hirayama F, Souza LM, Ogawa M: Interleukin 3 or interleukin 1 abrogates the reconstituting ability of hematopoietic stem cells. Proc Natl Acad Sci USA 93:4040, 1996
28. de Revel T, Appelbaum FR, Storb R, Schuening F, Nash R, Deeg J, McNiece I, Andrews R, Graham T: Effects of granulocyte colony stimulating factor and stem cell factor, alone and in combination, on the mobilization of peripheral blood cells that engraft lethally irradiated dogs. Blood 83:3795, 1994
29. Andrews RG, Briddell RA, Knitter GH, Opie T, Bronsden M, Myerson D, Appelbaum FR, McNiece IK: In vivo synergy between recombinant human stem cell factor and recombinant human granulocyte colony-stimulating factor in baboons: Enhanced circulation of progenitor cells. Blood 84:800, 1994
30. Elwood NJ, Zogos H, Willson T, Begley CG: Retroviral transduction of human progenitor cells: Use of granulocyte colony-stimulating factor plus stem cell factor to mobilize progenitor cells in vivo and stimulation by Flt3/Flk-2 ligand in vitro. Blood 88:4452, 1996
31. Andrews RG, Briddell RA, Knitter GH, Opie T, Bronsden M, Myerson D, Appelbaum FR, McNiece IK: In vivo synergy between recombinant human stem cell factor and recombinant human granulocyte colony-stimulating factor in baboons: Enhanced circulation of progenitor cells. Blood 84:800, 1994
32. Andrews RG, Bartelmez SH, Knitter GH, Myerson D, Bernstein ID, Appelbaum FR, Zsebo KM: A c-kit ligand, recombinant human stem cell factor, mediates reversible expansion of multiple CD34+ colony-forming cell types in blood and marrow of baboons. Blood 80:920, 1992
33. + cell dose predicts survival, posttransplant morbidity, and rate of hematologic recovery after allogeneic marrow transplants for hematologic malignancies. Blood 88:3223, 1996
34. Bodine DM, Seidel NE, Orlic D: Bone marrow collected 14 days after in vivo administration of granulocyte colony-stimulating factor and stem cell factor to mice has 10-fold more repopulating ability than untreated bone marrow. Blood 88:89, 1996
35. Pawliuk R, Eaves CJ, Humphries RK: Sustained high-level reconstitution of the hematopoietic system by preselected hematopoietic cells expressing a transduced cell-surface antigen. Hum Gene Ther 8:1595, 1997