Prolonged High-Level Detection of Retrovirally Marked Hematopoietic Cells in Nonhuman Primates after Transduction of CD34+ Progenitors Using Clinically Feasible Methods

Molecular Therapy

Volumn 1, Issue 3, 2000, Pages 285-293

  Wu, Tong ^a   Joon Kim, Hyeoung ^a   Sellers, Stephanie E ^a   Meade, Kristin E ^a   Agricola, Brian A ^a   Metzger, Mark E ^a   Kato, Ikunoshin ^c   Donahue, Robert E ^a   Dunbar, Cynthia E ^a   Tisdale, John F ^b  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c TAKARA SHUZO CO LTD   (Japan)

Author keywords

Hematopoietic stem cell; retroviral; gene transfer; rhesus; in vivo; stroma; fibronectin; flt3; megakaryocyte growth and development factor; engraftment

Indexed keywords

CD34 ANTIGEN; FIBRONECTIN; FLT3 LIGAND PROTEIN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 6; MEMBRANE PROTEIN; STEM CELL FACTOR; THROMBOPOIETIN;

ANIMAL; ARTICLE; CELL CULTURE; CLONOGENIC ASSAY; GENE TRANSFER; GENETICS; HEMATOPOIETIC STEM CELL; MACACA; METABOLISM; POLYMERASE CHAIN REACTION; RETROVIRUS; SOUTHERN BLOTTING; STROMA CELL;

ANIMALS; ANTIGENS, CD34; BLOTTING, SOUTHERN; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; FIBRONECTINS; GENE TRANSFER TECHNIQUES; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; INTERLEUKIN-3; INTERLEUKIN-6; MACACA MULATTA; MEMBRANE PROTEINS; POLYMERASE CHAIN REACTION; RETROVIRIDAE; STEM CELL FACTOR; STROMAL CELLS; THROMBOPOIETIN;

EID: 0034153385     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0034     Document Type: Article

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