Global brain gene expression analysis links Glutamatergic and GABAergic alterations to suicide and major depression

PLoS ONE

Volumn 4, Issue 8, 2009, Pages

  Sequeira, Adolfo ^a,d   Mamdani, Firoza ^a   Ernst, Carl ^a   Vawter, Marquis P ^d   Bunney, William E ^d   Lebel, Veronique ^a   Rehal, Sonia ^a   Klempan, Tim ^a   Gratton, Alain ^a   Benkelfat, Chawki ^b   Rouleau, Guy A ^c   Mechawar, Naguib ^a   Turecki, Gustavo ^a  

^a MCGILL UNIVERSITY   (Canada)

^b ROYAL VICTORIA HOSPITAL   (Canada)

^c UNIVERSITY OF MONTREAL   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ASSOCIATED PROTEIN LIKE 1; 4 AMINOBUTYRIC ACID A RECEPTOR DELTA; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA 1; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA 2; 4 AMINOBUTYRIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR RHO 1; AMPA RECEPTOR; AMPA RECEPTOR 1; AMPA RECEPTOR 3; GLUTAMATE AMMONIA LIGASE; GLUTAMATE RECEPTOR; MESSENGER RNA; NEUROTRANSMITTER TRANSPORTER; SOLUTE CARRIER FAMILY 6 MEMBER 1; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; GLUTAMIC ACID;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; COMORBIDITY; CONTROLLED STUDY; FOLLOW UP; GABAERGIC TRANSMISSION; GENE EXPRESSION PROFILING; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MICROARRAY ANALYSIS; MOLECULAR GENETICS; NEUROBIOLOGY; NONHUMAN; PREFRONTAL CORTEX; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUICIDE; SYNAPTIC TRANSMISSION; ADULT; ANIMAL; BRAIN; DNA MICROARRAY; GENETICS; METABOLISM; MIDDLE AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMALIA;

ADULT; ANIMALS; BRAIN; DEPRESSIVE DISORDER, MAJOR; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION PROFILING; GLUTAMIC ACID; HUMANS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUICIDE;

EID: 68749087317     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006585     Document Type: Article

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