Implication of SSAT by gene expression and genetic variation in suicide and major depression

Archives of General Psychiatry

Volumn 63, Issue 1, 2006, Pages 35-48

  Sequeira, Adolfo ^a   Gwadry, Fuad G ^b   Ffrench Mullen, Jarlath M H ^b   Canetti, Lilian ^a   Gingras, Yves ^a   Casero Jr , Robert A ^c   Rouleau, Guy ^a   Benkelfat, Chawki ^a   Turecki, Gustavo ^a  

^a MCGILL UNIVERSITY   (Canada)

^b Gene Logic Inc   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; SPERMINE SPERMIDINE N 1 ACETYLTRANSFERASE; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; BRAIN LEVEL; CLINICAL ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION; GENE LOCATION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR DEPRESSION; MALE; MEDICAL INSTRUMENTATION; MOTOR CORTEX; ORBITAL CORTEX; PREFRONTAL CORTEX; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUICIDE; VALIDATION PROCESS; WESTERN BLOTTING;

ACETYLTRANSFERASES; ADULT; BLOTTING, WESTERN; CEREBRAL CORTEX; CHROMOSOME MAPPING; CLUSTER ANALYSIS; DEPRESSIVE DISORDER, MAJOR; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOTOR CORTEX; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGONUCLEOTIDE PROBES; PREFRONTAL CORTEX; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUICIDE; VARIATION (GENETICS);

EID: 29844442061     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archpsyc.63.1.35     Document Type: Article

References (33)

1. Diekstra RFW. The epidemiology of suicide and parasuicide. Acta Psychiatr Scand Suppl. 1993;371:9-20.
2. Mann JJ, Brent DA, Arango V. The neurobiology and genetics of suicide and attempted suicide: a focus on the serotonergic system. Neuropsychopharmacology. 2001;24:467-477.
3. Kim C, Seguin M, Therrien N, Riopel G, Chawky N, Lesage A, Turecki G. Familial aggregation of suicidal behaviour: a family study of male suicide victims from the general population. Am J Psychiatry. 2005;162:1017-1019.
4. Statham DJ, Heath AC, Madden PA, Bucholz KK, Bierut L, Dinwiddie SH, Slutske WS, Dunne MP, Martin NG. Suicidal behaviour: an epidemiological and genetic study. Psychol Med. 1998;28:839-855.
5. Brent DA, Bridge J, Johnson BA, Connolly J. Suicidal behavior runs in families: a controlled family study of adolescent suicide victims. Arch Gen Psychiatry. 1996;53:1145-1152.
6. Brent DA, Oquendo M, Birmaher B, Greenhill L, Kolko D, Stanley B, Zelazny J, Brodsky B, Bridge J, Ellis S, Salazar JO, Mann JJ. Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters. Arch Gen Psychiatry. 2002;59:801-807.
7. Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM. Neurobiology of depression. Neuron. 2002;34:13-25.
8. Gross-Isseroff R, Biegon A, Voet H, Weizman A. The suicide brain: a review of postmortem receptor/transporter binding studies. Neurosci Biobehav Rev. 1998;22:653-661.
9. Sheline YI. Neuroimaging studies of mood disorder effects on the brain. Biol Psychiatry. 2003;54:338-352.
10. Wolff EA III, Putnam FW, Post RM. Motor activity and affective illness: the relationship of amplitude and temporal distribution to changes in affective state. Arch Gen Psychiatry. 1985;42:288-294.
11. Schwartz F, Carr AC, Munich RL, Glauber S, Lesser B, Murray J. Reaction time impairment in schizophrenia and affective illness: the role of attention. Biol Psychiatry. 1989;25:540-548.
12. Rogowska J, Gruber SA, Yurgelun-Todd DA. Functional magnetic resonance imaging in schizophrenia: cortical response to motor stimulation. Psychiatry Res. 2004;130:227-243.
13. Simard LR, Prescott G, Rochette C, Morgan K, Lemieux B, Mathieu J, Melancon SB, Vanasse M. Linkage disequilibrium analysis of childhood-onset spinal muscular atrophy (SMA) in the French-Canadian population. Hum Mol Genet. 1994;3:459-463.
14. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1989.
15. Sequeira A, Mamdani F, Lalovic A, Anguelova M, Lesage A, Seguin M, Chawky N, Desautels A, Turecki G. Alpha 2A adrenergic receptor gene and suicide. Psychiatry Res. 2004;125:87-93.
16. Lindblad-Toh K, Winchester E, Daly MJ, Wang DG, Hirschhorn JN, Laviolette JP, Ardlie K, Reich DE, Robinson E, Sklar P, Shah N, Thomas D, Fan JB, Gingeras T, Warrington J, Patil N, Hudson TJ, Lander ES. Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse. Nat Genet. 2000;24:381-386.
17. Tomita H, Vawter MP, Walsh DM, Evans SJ, Choudary PV, Li J, Overman KM, Atz ME, Myers RM, Jones EG, Watson SJ, Akil H, Bunney WE Jr. Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain. Biol Psychiatry. 2004;55:346-352.
18. Li JZ, Vawter MP, Walsh DM, Tomita H, Evans SJ, Choudary PV, Lopez JF, Avelar A, Shokoohi V, Chung T, Mesarwi O, Jones EG, Watson SJ, Akil H, Bunney WE Jr, Myers RM. Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. Hum Mol Genet. 2004;13:609-616.
19. Barton AJ, Pearson RC, Najlerahim A, Harrison PJ. Pre- and postmortem influences on brain RNA. J Neurochem. 1993;61:1-11.
20. 1- acetyltransferase in MALME-3M human melanoma cells. J Biol Chem. 1993;268:19 118-19 125.
21. 1-acetyltransferase (SSAT) gene in human lung carcinoma cells. Biochem J. 1996;313:691-696.
22. 1-acetyltransferase superinduced in response to treatment with antitumor polyamine analogues. Cancer Res. 1994;54:3955-3958.
23. 1-acetyltransferase gene transcription. J Biol Chem. 1998;273:34623-34630.
24. 1- acetyltransferase: the turning point in polyamine metabolism. FASEB J. 1993;7:653-661.
25. Gilad GM, Gilad VH. Stress-induced dynamic changes in mouse brain polyamines: role in behavioral reactivity. Brain Res. 2002;943:23-29.
26. Gilad VH, Rabey JM, Kimiagar Y, Gilad GM. The polyamine stress response: tissue-, endocrine-, and developmental-dependent regulation. Biochem Pharmacol. 2001;61:207-213.
27. Masuko T, Kusama-Eguchi K, Sakata K, Kusama T, Chaki S, Okuyama S, Williams K, Kashiwagi K, Igarashi K. Polyamine transport, accumulation, and release in brain. J Neurochem. 2003;84:610-617.
28. Gilad GM, Gilad VH, Wyatt RJ, Casero RA Jr. Chronic lithium treatment prevents the dexamethasone-induced increase of brain polyamine metabolizing enzymes. Life Sci. 1992;50:PL149-PL154.
29. Gilad GM, Gilad VH, Casanova MF, Casero RA Jr. Polyamines and their metabolizing enzymes in human frontal cortex and hippocampus: preliminary measurements in affective disorders. Biol Psychiatry. 1995;38:227-234.
30. Li M, Farley RA, Lester HA. Voltage-dependent transient currents of human and rat 5-HT transporters (SERT) are blocked by HEPES and ion channel ligands. FEBS Lett. 2002;513:247-252.
31. Williams K. Interactions of polyamines with ion channels. Biochem J. 1997;325:289-297.
32. Sibille E, Arango V, Galfalvy HC, Pavlidis P, Erraji-Benchekroun L, Ellis SP, John MJ. Gene expression profiling of depression and suicide in human prefrontal cortex. Neuropsychopharmacology. 2004;29:351-361.
33. Galfalvy HC, Erraji-Benchekroun L, Smyrniotopoulos P, Pavlidis P, Ellis SP, Mann JJ, Sibille E, Arango V. Sex genes for genomic analysis in human brain: internal controls for comparison of probe level data extraction. BMC Bioinformatics. 2003;4:37. Available at: http://www.biomedcentral.com/1471-2105/ 4/37. Access verified December 1, 2005.