An Essential Role for RIG-I in Toll-like Receptor-Stimulated Phagocytosis

Cell Host and Microbe

Volumn 6, Issue 2, 2009, Pages 150-161

  Kong, Ling ^a,d   Sun, Lei ^a,d   Zhang, Hongxin ^b   Liu, Qin ^a   Liu, Ye ^a   Qin, Linhua ^a   Shi, Guojun ^a,d   Hu, Jun Hao ^a,d   Xu, Ajing ^a   Sun, Yue Ping ^b   Li, Dangsheng ^e   Shi, Yu Fang ^a   Zang, Jing Wu ^a   Zhu, Jiang ^c   Chen, Zhu ^c   Wang, Zhu Gang ^b,c   Ge, Bao Xue ^a  

^a SHANGHAI UNIVERSITY OF MEDICINE AND HEALTH SCIENCES   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^e Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

CELLBIO; MICROBIO; MOLIMMUNO

Indexed keywords

ACTIN RELATED PROTEIN 2-3 COMPLEX; LIPOPOLYSACCHARIDE; PROTEIN CDC42; RAC1 PROTEIN; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; CELL STIMULATION; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE TARGETING; HUMAN; HUMAN CELL; INFECTION SENSITIVITY; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PERITONITIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WILD TYPE;

ACTIN-RELATED PROTEIN 2-3 COMPLEX; ANIMALS; CELL LINE; DEAD-BOX RNA HELICASES; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; GENE SILENCING; GTPASE-ACTIVATING PROTEINS; MACROPHAGES; MICE; MICE, KNOCKOUT; NEUROPEPTIDES; PHAGOCYTOSIS; RAC GTP-BINDING PROTEINS; RNA, SMALL INTERFERING; SURVIVAL ANALYSIS; TOLL-LIKE RECEPTOR 4;

ESCHERICHIA COLI; MUS;

EID: 68549132515     PISSN: 19313128     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chom.2009.06.008     Document Type: Article

References (47)

1. Aderem A., and Underhill D.M. Mechanisms of phagocytosis in macrophages. Annu. Rev. Immunol. 17 (1999) 593-623
2. Akira S., and Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 4 (2004) 499-511
3. Akira S., Uematsu S., and Takeuchi O. Pathogen recognition and innate immunity. Cell 124 (2006) 783-801
4. Beutler B., and Kruys V. Lipopolysaccharide signal transduction, regulation of tumor necrosis factor biosynthesis, and signaling by tumor necrosis factor itself. J. Cardiovasc. Pharmacol. 25 (1995) S1-S8
5. Blander J.M., and Medzhitov R. Regulation of phagosome maturation by signals from toll-like receptors. Science 304 (2004) 1014-1018
6. Caron E., and Hall A. Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 282 (1998) 1717-1721
7. Castellano F., Chavrier P., and Caron E. Actin dynamics during phagocytosis. Semin. Immunol. 13 (2001) 347-355
8. Chimini G., and Chavrier P. Function of Rho family proteins in actin dynamics during phagocytosis and engulfment. Nat. Cell Biol. 2 (2000) E191-E196
9. Cox D., Chang P., Zhang Q., Reddy P.G., Bokoch G.M., and Greenberg S. Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes. J. Exp. Med. 186 (1997) 1487-1494
10. Cui X.F., Imaizumi T., Yoshida H., Borden E.C., and Satoh K. Retinoic acid-inducible gene-I is induced by interferon-gamma and regulates the expression of interferon-gamma stimulated gene 15 in MCF-7 cells. Biochem. Cell Biol. 82 (2004) 401-405
11. Doyle S.E., O'Connell R.M., Miranda G.A., Vaidya S.A., Chow E.K., Liu P.T., Suzuki S., Suzuki N., Modlin R.L., Yeh W.C., et al. Toll-like receptors induce a phagocytic gene program through p38. J. Exp. Med. 199 (2004) 81-90
12. Fitzgerald K.A., McWhirter S.M., Faia K.L., Rowe D.C., Latz E., Golenbock D.T., Coyle A.J., Liao S.M., and Maniatis T. IKKε and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 4 (2003) 491-496
13. Greenberg S., and Grinstein S. Phagocytosis and innate immunity. Curr. Opin. Immunol. 14 (2002) 136-145
14. Hargreaves D.C., and Medzhitov R. Innate sensors of microbial infection. J. Clin. Immunol. 25 (2005) 503-510
15. Hemmi H., Takeuchi O., Sato S., Yamamoto M., Kaisho T., Sanjo H., Kawai T., Hoshino K., Takeda K., and Akira S. The roles of two IκB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. J. Exp. Med. 199 (2004) 1641-1650
16. Henson P.M., Bratton D.L., and Fadok V.A. Apoptotic cell removal. Curr. Biol. 11 (2001) R795-R805
17. Henson P.M., Bratton D.L., and Fadok V.A. The phosphatidylserine receptor: a crucial molecular switch. Nat. Rev. Mol. Cell Biol. 2 (2001) 627-633
18. Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434 (2005) 772-777
19. Imaizumi T., Aratani S., Nakajima T., Carlson M., Matsumiya T., Tanji K., Ookawa K., Yoshida H., Tsuchida S., McIntyre T.M., et al. Retinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2. Biochem. Biophys. Res. Commun. 292 (2002) 274-279
20. Imaizumi T., Hatakeyama M., Yamashita K., Ishikawa A., Yoshida H., Satoh K., Taima K., Mori F., and Wakabayashi K. Double-stranded RNA induces the synthesis of retinoic acid-inducible gene-I in vascular endothelial cells. Endothelium 12 (2005) 133-137
21. Kato H., Sato S., Yoneyama M., Yamamoto M., Uematsu S., Matsui K., Tsujimura T., Takeda K., Fujita T., Takeuchi O., et al. Cell type-specific involvement of RIG-I in antiviral response. Immunity 23 (2005) 19-28
22. Kato H., Takeuchi O., Sato S., Yoneyama M., Yamamoto M., Matsui K., Uematsu S., Jung A., Kawai T., Ishii K.J., et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441 (2006) 101-105
23. Kawai T., Takahashi K., Sato S., Coban C., Kumar H., Kato H., Ishii K.J., Takeuchi O., and Akira S. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6 (2005) 981-988
24. Kong L., and Ge B.X. Toll-like receptors regulates phagocytosis through MyD88-independent actin-Cdc42/Rac pathway. Cell Res. 18 (2008) 745-755
25. Liu C.Z., Chen Y., and Sui S.F. The identification of a new actin-binding region in p57. Cell Res. 16 (2006) 106-112
26. Ma L., Rohatgi R., and Kirschner M.W. The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42. Proc. Natl. Acad. Sci. USA 95 (1998) 15362-15367
27. Marion G., Wolfgang H., Dieter M., Sonja L., Klaus W., Bettina B.M., Werner L., and Peter P. Dermal microvascular endothelial cells expresses the 180-kDa macrophage mannose receptor in situ and in vitro. J. Immunol. 165 (2000) 5428-5434
28. Mellman I. Endocytosis and antigen processing. Semin. Immunol. 2 (1990) 229-237
29. Meylan E., Curran J., Hofmann K., Moradpour D., Binder M., Bartenschlager R., and Tschopp J. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437 (2005) 1167-1172
30. Mukherjee A., Morosky S.A., Shen L., Weber C.R., Turner J.R., Kim K.S., Wang T., and Coyne C.B. Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions. J. Biol. Chem. 284 (2009) 6486-6494
31. Ono K., and Han J. The p38 signal transduction pathway activation and function. Cell. Signal. 12 (2000) 1-13
32. Ozinsky A., Underhill D.M., Fontenot J.D., Hajjar A.M., Smith K.D., Wilson C.B., Schroeder L., and Aderem A. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc. Natl. Acad. Sci. USA 97 (2000) 13766-13771
33. Poltorak A., He X., Smirnova I., Liu M.Y., Van Huffel C., Du X., Birdwell D., Alejos E., Silva M., Galanos C., et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282 (1998) 2085-2088
34. Sakaki H., Imaizumi T., Matsumiya T., Kusumi A., Nakagawa H., Kubota K., Nishi N., Nakamura T., Hirashima M., Satoh K., et al. Retinoic acid-inducible gene-I is induced by interleukin-1beta in cultured human gingival fibroblasts. Oral Microbiol. Immunol. 20 (2005) 47-50
35. Sato M., Suemori H., Hata N., Asagiri M., Ogasawara K., Nakao K., Nakaya T., Katsuki M., Noguchi S., Tanaka N., et al. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-α/β gene induction. Immunity 13 (2000) 539-548
36. Seth R.B., Sun L., Ea C.K., and Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF-3. Cell 122 (2005) 669-682
37. Sharma S., TenOever B.R., Grandvaux N., Zhou G.P., Lin R., and Hiscott J. Triggering the interferon antiviral response through an IKK-related pathway. Science 300 (2003) 1148-1151
38. Sun, Y.W. (1997). RIG-I, a human homolog gene of RNA helicase, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell. PhD thesis, Shanghai Institute of Heamatology, Rui-Jin Hospital, Shanghai Second Medical University.
39. Underhill D.M., and Ozinsky A. phagocytosis of microbes: complexity in action. Annu. Rev. Immunol. 20 (2002) 825-852
40. Underhill D.M., Ozinsky A., Hajjar A.M., Stevens A., Wilson C.B., Bassetti M., and Aderem A. The toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401 (1999) 811-815
41. Wang Y., Zhang H.X., Sun Y.P., Liu Z.X., Liu X.S., Wang L., Lu S.Y., Kong H., Liu Q.L., Li X.H., et al. Rig-I(-/-) mice develop colitis associated with downregulation of Galphai2. Cell Res. 17 (2007) 858-868
42. Weijer S., Sewnath M.E., de Vos A.F., Florquin S., van der Sluis K., Gouma D.J., Takeda K., Akira S., and van der Poll T. Interleukin-18 facilitates the early antimicrobial host response to Escherichia coli peritonitis. Infect. Immun. 71 (2003) 5488-5497
43. Williams L.M., and Ridley A.J. Lipopolysaccharide induces actin reorganization and tyrosine phosphorylation of Pyk2 and paxillin in monocytes and macrophages. J. Immunol. 164 (2000) 2028-2036
44. Xu L.G., Wang Y.Y., Han K.J., Li L.Y., Zhai Z., and Shu H.B. VISA is an adapter protein required for virus-triggered IFN-β signaling. Mol. Cell 19 (2005) 727-740
45. Yates R.M., and Russell D.G. Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4. Immunity 23 (2005) 409-417
46. Yoneyama M., Kikuchi M., Natsukawa T., Shinobu N., Imaizumi T., Miyagishi M., Taira K., Akira S., and Fujita T. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5 (2004) 730-737
47. Zhang N.N., Shen S.H., Jiang L.J., Zhang W., Zhang H.X., Sun Y.P., Li X.Y., Huang Q.H., Ge B.X., Chen S.J., et al. RIG-I plays a critical role in negatively regulating granulocytic proliferation. Proc. Natl. Acad. Sci. USA 105 (2008) 10553-10558