메뉴 건너뛰기




Volumn 4, Issue 7, 2009, Pages 891-910

Prognostic and predictive markers of benefit from adjuvant chemotherapy in early-stage non-small cell lung cancer

Author keywords

Early stages; Molecular prognostic and predictive markers; Non small cell lung cancer; Platinumbased adjuvant chemotherapy

Indexed keywords

BETA TUBULIN; BRCA1 PROTEIN; CARBOPLATIN; CISPLATIN; DOCETAXEL; ETOPOSIDE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; GEMCITABINE; MOLECULAR MARKER; NAVELBINE; PACLITAXEL; PROTEIN P53; RIBONUCLEOTIDE REDUCTASE; RIBONUCLEOTIDE REDUCTASE SUBUNIT M1; UNCLASSIFIED DRUG; VINCA ALKALOID; VINCRISTINE;

EID: 68549127070     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3181a4b8fb     Document Type: Review
Times cited : (49)

References (144)
  • 2
    • 34547756731 scopus 로고    scopus 로고
    • Surgical treatment of non small cell lung cancer
    • Shields TW, Lo Cicero J III, Ponn R, Rusch VW (Eds.), Philadelphia: Lippincott Williams & Wilkins
    • Ponn RB, Lo Cicero J III, Daly BDT. Surgical treatment of non small cell lung cancer. In Shields TW, Lo Cicero J III, Ponn R, Rusch VW (Eds.). General Thoracic Surgery, 6th Ed. Philadelphia: Lippincott Williams & Wilkins, 2005. Pp. 1548-1587.
    • (2005) General Thoracic Surgery, 6th Ed. , pp. 1548-1587
    • Ponn, R.B.1    Lo Cicero III, J.2    Daly, B.D.T.3
  • 3
    • 33745870113 scopus 로고    scopus 로고
    • Surgery for non-small cell lung cancer: Systematic review and meta-analysis of randomised controlled trials
    • DOI 10.1136/thx.2005.051995
    • Wright G, Manser RL, Byrnes G, Hart D, Campbell DA. Surgery for early-stage non-small cell lung cancer: systematic review and metaanalysis of randomised controlled trials. Thorax 2006;61:597-603. (Pubitemid 44035140)
    • (2006) Thorax , vol.61 , Issue.7 , pp. 597-603
    • Wright, G.1    Manser, R.L.2    Byrnes, G.3    Hart, D.4    Campbell, D.A.5
  • 4
    • 17044393041 scopus 로고    scopus 로고
    • Adjuvant chemotherapy of lung cancer: Methodologic issues and therapeutic advances
    • DOI 10.1016/j.hoc.2005.02.008
    • Strauss GM. Adjuvant chemotherapy of lung cancer: methodologic issues and therapeutic advances. Hematol Oncol Clin North Am 2005; 19:263-281. (Pubitemid 40502853)
    • (2005) Hematology/Oncology Clinics of North America , vol.19 , Issue.2 , pp. 263-281
    • Strauss, G.M.1
  • 8
    • 33747820148 scopus 로고    scopus 로고
    • Lung adjuvant cisplatin evaluation (LACE): A pooled analysis of 5 randomized trials including 4584 patients
    • [Abstract No.7008 2006 ASCO Annual Meeting.]
    • Pignon JP, Tribodet H, Scagliotti GV, et al. Lung Adjuvant Cisplatin Evaluation (LACE): a pooled analysis of 5 randomized trials including 4584 patients. J Clin Oncol 2006;24:366S. [Abstract No. 7008 2006 ASCO Annual Meeting.]
    • (2006) J Clin Oncol , vol.24
    • Pignon, J.P.1    Tribodet, H.2    Scagliotti, G.V.3
  • 9
    • 10244233949 scopus 로고    scopus 로고
    • Randomized clinical trial of adjuvant chemotherapy with paclitaxel and carboplatin following resection in stage IB non-small cell lung cancer (NSCLC): Report of cancer and leukemia group B (CALGB) protocol 9633
    • Strauss GM, Herndon JE, Maddaus MA, et al. Randomized clinical trial of adjuvant chemotherapy with paclitaxel and carboplatin following resection in stage IB non-small cell lung cancer (NSCLC): report of Cancer and Leukemia Group B (CALGB) Protocol 9633. J Clin Oncol 2004;22:7019.
    • (2004) J Clin Oncol , vol.22 , pp. 7019
    • Strauss, G.M.1    Herndon, J.E.2    Maddaus, M.A.3
  • 10
    • 55549138045 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in stage IB non-small cell lung cancer (NSCLC): Update of cancer and leukemia group B (CALGB) protocol 9633
    • [Abstract No. 7007 2006 ASCO Annual Meeting.]
    • Strauss GM, Herndon JE, Maddaus MA, et al. Adjuvant chemotherapy in stage IB non-small cell lung cancer (NSCLC): update of cancer and Leukemia Group B (CALGB) protocol 9633. J Clin Oncol 2008;26: 5043-5051. [Abstract No. 7007 2006 ASCO Annual Meeting.]
    • (2008) J Clin Oncol , vol.26 , pp. 5043-5051
    • Strauss, G.M.1    Herndon, J.E.2    Maddaus, M.A.3
  • 12
    • 15044352688 scopus 로고    scopus 로고
    • Clinical model to predict survival in chemonaive patients with advanced non-small-cell lung cancer treated with third-generation chemotherapy regimens based on Eastern Cooperative Oncology Group data
    • DOI 10.1200/JCO.2005.04.177
    • Hoang T, Xu R, Schiller JH, Bonomi P, Johnson DH. Clinical model to predict survival in chemonaïve patients with advanced non-small-cell lung cancer treated with third-generation chemotherapy regimens based on eastern cooperative oncology group data. J Clin Oncol 2005;23: 175-183. (Pubitemid 41702636)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.1 , pp. 175-183
    • Hoang, T.1    Xu, R.2    Schiller, J.H.3    Bonomi, P.4    Johnson, D.H.5
  • 13
    • 20344377869 scopus 로고    scopus 로고
    • A prospective longitudinal study of performance status, an inflammation-based score (GPS) and survival in patients with inoperable non-small-cell lung cancer
    • DOI 10.1038/sj.bjc.6602591
    • Forrest LM, McMillan DC, McArdle CS, Angerson WT, Dagg K, Scott HR. A prospective longitudinal study of performance status, an inflammation- based score (GPS) and survival in patients with inoperable non-small-cell lung cancer. Br J Cancer 2005;92:1834-1836. (Pubitemid 40826128)
    • (2005) British Journal of Cancer , vol.92 , Issue.10 , pp. 1834-1836
    • Forrest, L.M.1    McMillan, D.C.2    McArdle, C.S.3    Angerson, W.J.4    Dagg, K.5    Scott, H.R.6
  • 14
    • 0036384579 scopus 로고    scopus 로고
    • Prognostic factors in nonsmall cell lung cancer: A decade of progress
    • Brundage MD, Davies D, Mackillop WJ. Prognostic factors in nonsmall cell lung cancer: a decade of progress. Chest 2002;122:1037-1057.
    • (2002) Chest , vol.122 , pp. 1037-1057
    • Brundage, M.D.1    Davies, D.2    Mackillop, W.J.3
  • 15
    • 19844380235 scopus 로고    scopus 로고
    • Genomic and proteomic profiling of lung cancers: Lung cancer classification in the age of targeted therapy
    • DOI 10.1200/JCO.2005.15.511
    • Meyerson M, Carbone DP. Genomic and proteomic profiling of lung cancers: lung cancer classification in the age of targeted therapy. J Clin Oncol 2005;23:3219-3226. (Pubitemid 46211346)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.14 , pp. 3219-3226
    • Meyerson, M.1    Carbone, D.2
  • 16
    • 1542608359 scopus 로고    scopus 로고
    • Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction
    • DOI 10.1200/JCO.2004.04.109
    • Endoh H, Tomida S, Yatabe Y, et al. Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction. J Clin Oncol 2004;22:811-819. (Pubitemid 41103592)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.5 , pp. 811-819
    • Endoh, H.1    Tomida, S.2    Yatabe, Y.3    Konishi, H.4    Osada, H.5    Tajima, K.6    Kuwano, H.7    Takahashi, T.8    Mitsudomi, T.9
  • 18
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer DG, Kardia SL, Huang CC, et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 2002;8:816-824.
    • (2002) Nat Med , vol.8 , pp. 816-824
    • Beer, D.G.1    Kardia, S.L.2    Huang, C.C.3
  • 20
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena M, Shalon D, Davis RW, Brown PO. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995;270:467-470.
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 21
    • 33644844520 scopus 로고    scopus 로고
    • Microarray technology: Beyond transcript profiling and genotype analysis
    • Hoheisel JD. Microarray technology: beyond transcript profiling and genotype analysis. Nat Rev Genet 2006;7:200-210.
    • (2006) Nat Rev Genet , vol.7 , pp. 200-210
    • Hoheisel, J.D.1
  • 22
    • 2342631260 scopus 로고    scopus 로고
    • Translating cancer genomics into clinical oncology
    • DOI 10.1056/NEJMp048059
    • Ramaswamy S. Tranlating cancer genomics into clinical oncology. N Engl J Med 2004;350:1814-1816. (Pubitemid 38917246)
    • (2004) New England Journal of Medicine , vol.350 , Issue.18 , pp. 1814-1816
    • Ramaswamy, S.1
  • 27
    • 1042302005 scopus 로고    scopus 로고
    • The stats of cancer - New molecular targets come of age
    • Yu H, Jove R. The STATs of cancer-new molecular targets come on age. Nat Rev Cancer 2004;4:97-105. (Pubitemid 38198738)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 28
    • 0030659512 scopus 로고    scopus 로고
    • Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
    • DOI 10.1126/science.278.5343.1630
    • Kumar A, Commane M, Flickinger TW, Horvath CM, Stark GR. Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 1997;278:1630-1632. (Pubitemid 27516283)
    • (1997) Science , vol.278 , Issue.5343 , pp. 1630-1632
    • Kumar, A.1    Commane, M.2    Flickinger, T.W.3    Horvath, C.M.4    Stark, G.R.5
  • 29
    • 0029590749 scopus 로고
    • Molecular cloning of a novel macrophage maturation-associated transcript encoding a protein with several potential transmembrane domains
    • DOI 10.1006/bbrc.1995.2825
    • Rehli M, Krause SW, Schwarzfischer L, Kreutz M, Andreesen R. Molecular cloning of a novel macrophage maturation-associated transcript encoding a protein with several potential transmembrane domains. Biochem Biophys Res Commun 1995;217:661-667. (Pubitemid 26011760)
    • (1995) Biochemical and Biophysical Research Communications , vol.217 , Issue.2 , pp. 661-667
    • Rehli, M.1    Krause, S.W.2    Schwarzfischer, L.3    Kreutz, M.4    Andreesen, R.5
  • 33
    • 0037307095 scopus 로고    scopus 로고
    • The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation
    • DOI 10.1034/j.1600-065X.2003.00015.x
    • Zamoyska R, Basson A, Filby A, Legname G, Lovatt M, Seddon B. The influence of the src-family kinases, on T cell differentiation, survival and activation. Immunol Rev 2003;191:107-118. (Pubitemid 36398852)
    • (2003) Immunological Reviews , vol.191 , pp. 107-118
    • Zamoyska, R.1    Basson, A.2    Filby, A.3    Legname, G.4    Lovatt, M.5    Seddon, B.6
  • 34
    • 1642373712 scopus 로고    scopus 로고
    • lck-induced Cell Motility, and Urokinase-type Plasminogen Activator Secretion Involve Activation of Epidermal Growth Factor Receptor/Extracellular Signal Regulated Kinase Pathways
    • DOI 10.1074/jbc.M311400200
    • Mahabeleshwar GH, Das R, Kundu GC. Tyrosine Kinase, p56lckinduced cell motility, and urokinase-type plasminogen activator secretion involve activation of epidermal growth factor receptor/extracellular regulated kinase pathways. J Biol Chem 2004;279:9733-9742. (Pubitemid 38372571)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.11 , pp. 9733-9742
    • Mahabeleshwar, G.H.1    Das, R.2    Kundu, G.C.3
  • 35
    • 0346101761 scopus 로고    scopus 로고
    • Tyrosine kinase p56lck regulates cell motility and nuclear factor kappa B-mediated secretion of urokinase type plasminogen activator through tyrosine phosphorylation of IkappaBalpha following hipoxia/reoxygenation
    • Mahabeleshwar GH, Kundu GC. Tyrosine Kinase p56lck regulates cell motility and nuclear factor kappa B-mediated secretion of urokinase type plasminogen activator through tyrosine phosphorylation of IkappaBalpha following hipoxia/reoxygenation. J Biol Chem 2003;278: 52598-52612.
    • (2003) J Biol Chem , vol.278 , pp. 52598-52612
    • Mahabeleshwar, G.H.1    Kundu, G.C.2
  • 36
    • 68549120489 scopus 로고    scopus 로고
    • Expression profile of 29 genes by real-time quantitative PCR (RT-QPCR) in early-stage (I-IIIA) squamous cell carcinoma of the lung (SCCL)
    • abstract 7612
    • Skrzypski M, Jassem E, Mendez P, et al. Expression profile of 29 genes by real-time quantitative PCR (RT-QPCR) in early-stage (I-IIIA) squamous cell carcinoma of the lung (SCCL). J Clin Oncol 2007; 25(supp):abstract 7612.
    • (2007) J Clin Oncol , vol.25 , Issue.SUPPL.
    • Skrzypski, M.1    Jassem, E.2    Mendez, P.3
  • 37
    • 59449100715 scopus 로고    scopus 로고
    • Validation of 5- and 3-gene expression signatures for predicting outcome in non-small cell lung cancer (NSCLC) patients (p)
    • abstract 7532
    • Skrzypski M, Jassem E, Benlloch S, et al. Validation of 5- and 3-gene expression signatures for predicting outcome in non-small cell lung cancer (NSCLC) patients (p). J Clin Oncol 2008;26(supp):abstract 7532.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Skrzypski, M.1    Jassem, E.2    Benlloch, S.3
  • 38
    • 59449101845 scopus 로고    scopus 로고
    • A 15-gene expression signature prognostic for survival and predictive for adjuvant chemotherapy benefit in JBR. 10 patients
    • abstract 7510
    • Tsao MS, Zhu C, Ding K, et al. A 15-gene expression signature prognostic for survival and predictive for adjuvant chemotherapy benefit in JBR. 10 patients. J Clin Oncol 2008;26(supp):abstract 7510.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Tsao, M.S.1    Zhu, C.2    Ding, K.3
  • 39
    • 55449138473 scopus 로고    scopus 로고
    • Long-term results of the internacional adjuvant lung cancer trial (IALT) evaluating adjuvant cisplatin-based chemotherapy in resected non-small cell lung cancer (NSCLC)
    • abstract 7507
    • Le Chevalier T, Dunant A, Arriagada R, et al. Long-term results of the Internacional Adjuvant Lung Cancer Trial (IALT) evaluating adjuvant cisplatin-based chemotherapy in resected non-small cell lung cancer (NSCLC). J Clin Oncol 2008;26(supp):abstract 7507.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Le Chevalier, T.1    Dunant, A.2    Arriagada, R.3
  • 41
    • 0031791029 scopus 로고    scopus 로고
    • Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy
    • Reed E. Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy. Cancer Treat Rev 1998;24:331-344. (Pubitemid 28537769)
    • (1998) Cancer Treatment Reviews , vol.24 , Issue.5 , pp. 331-344
    • Reed, E.1
  • 42
    • 0029783348 scopus 로고    scopus 로고
    • Repair of cisplatin-DNA adducts by the mammalian excision nuclease
    • DOI 10.1021/bi960453+
    • Zamble DB, Mu D, Reardon JT, Sancar A, Lippard SJ. Repair of cisplatin-DNA adducts by the mammalian excision nuclease. Biochemistry 1996;35:10004-10013. (Pubitemid 26269915)
    • (1996) Biochemistry , vol.35 , Issue.31 , pp. 10004-10013
    • Zamble, D.B.1    Mu, D.2    Reardon, J.T.3    Sancar, A.4    Lippard, S.J.5
  • 43
    • 0033781210 scopus 로고    scopus 로고
    • Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells
    • DOI 10.1128/MCB.20.21.7980-7990.2000
    • De Silva IU, McHugh PJ, Clingen PH, Hartley JA. Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol Cell Biol 2000;20: 7980-7990. (Pubitemid 30777715)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.21 , pp. 7980-7990
    • De Silva, I.U.1    McHugh, P.J.2    Clingen, P.H.3    Hartley, J.A.4
  • 46
    • 21644466123 scopus 로고    scopus 로고
    • Escisión repair cross complementing- Group 1: Gene expresion and platinum resistance
    • Altaha R, Liang X, Yu JJ, Reed E. Escisión repair cross complementing- group 1: gene expresion and platinum resistance. Int J Mol Med 2004;14:959-970.
    • (2004) Int J Mol Med , vol.14 , pp. 959-970
    • Altaha, R.1    Liang, X.2    Yu, J.J.3    Reed, E.4
  • 48
    • 4143051317 scopus 로고    scopus 로고
    • Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy
    • DOI 10.1158/1078-0432.CCR-04-0247
    • Zhou W, Gurubhagavatula S, Liu G, et al. Excision repair crosscomplementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinumbased chemotherapy. Clin Cancer Res 2004;10:4939-4943. (Pubitemid 39099767)
    • (2004) Clinical Cancer Research , vol.10 , Issue.15 , pp. 4939-4943
    • Zhou, W.1    Gurubhagavatula, S.2    Liu, G.3    Park, S.4    Neuberg, D.S.5    Wain, J.C.6    Lynch, T.J.7    Su, L.8    Christiani, D.C.9
  • 49
    • 24344479165 scopus 로고    scopus 로고
    • ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer
    • DOI 10.1158/1078-0432.CCR-04-2216
    • Viguier J, Boige V, Miquel C, et al. ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluoruracil combination chemotherapy in patients with advanced colorectal cancer. Clin Cancer Res 2005;11:6212-6217. (Pubitemid 41262950)
    • (2005) Clinical Cancer Research , vol.11 , Issue.17 , pp. 6212-6217
    • Viguier, J.1    Boige, V.2    Miquel, C.3    Pocard, M.4    Giraudeau, B.5    Sabourin, J.-C.6    Ducreux, M.7    Sarasin, A.8    Praz, F.9
  • 50
    • 15844372318 scopus 로고    scopus 로고
    • ERCC1 expression is a predictor of survival in resected patients with non-small cell lung cancer
    • DOI 10.1378/chest.127.3.978
    • Simon GR, Sharma S, Cantor A, Smith P, Bepler G. ERCC1 expression is a predictor of survival in resected patients with non-small cell lung cancer. Chest 2005;127:978-983. (Pubitemid 40775532)
    • (2005) Chest , vol.127 , Issue.3 , pp. 978-983
    • Simon, G.R.1    Sharma, S.2    Cantor, A.3    Smith, P.4    Bepler, G.5
  • 52
    • 0038636459 scopus 로고    scopus 로고
    • RRM1-induced metastasis suppression through PTEN-regulated pathways
    • DOI 10.1038/sj.onc.1206232
    • Gautam A, Li ZR, Bepler G. RRM1-induced metastasis suppresion through PTEN-regulated pathways. Oncogene 2003;22:2135-2142. (Pubitemid 36539563)
    • (2003) Oncogene , vol.22 , Issue.14 , pp. 2135-2142
    • Gautam, A.1    Li, Z.-R.2    Bepler, G.3
  • 55
    • 33746164472 scopus 로고    scopus 로고
    • Suppression of lung tumor formation by the regulatory subunit of ribonucleotide reductase
    • DOI 10.1158/0008-5472.CAN-05-4462
    • Gautam A, Bepler G. Suppression of lung tumor formation by the regulatory subunit of ribonucleotide reductase. Cancer Res 2006;66: 6497-6502. (Pubitemid 44085603)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6497-6502
    • Gautam, A.1    Bepler, G.2
  • 58
    • 23844515641 scopus 로고    scopus 로고
    • A randomized phase III trial of gemcitabine in combination with carboplatin or paclitaxel versus paclitaxel plus carboplatin in advanced non-small cell lung cancer: Update of the alpha oncology trial (A1-99002L)
    • Abstract
    • Treat J, Belani C, Edelman M, et al. A randomized phase III trial of gemcitabine in combination with carboplatin or paclitaxel versus paclitaxel plus carboplatin in advanced non-small cell lung cancer: update of the Alpha Oncology trial (A1-99002L). Proc Am Soc Clin Oncol 2005;23:627s. Abstract.
    • (2005) Proc Am Soc Clin Oncol , vol.23
    • Treat, J.1    Belani, C.2    Edelman, M.3
  • 61
    • 29844434293 scopus 로고    scopus 로고
    • Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis
    • DOI 10.1093/jnci/dji427
    • McCabe A, Dolled-Filhart M, Camp RL, Rimm DL. Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis. J Natl Cancer Inst 2005;97:1808-1815. (Pubitemid 43033901)
    • (2005) Journal of the National Cancer Institute , vol.97 , Issue.24 , pp. 1808-1815
    • McCabe, A.1    Dolled-Filhart, M.2    Camp, R.L.3    Rimm, D.L.4
  • 62
    • 0037190607 scopus 로고    scopus 로고
    • BRCA1: Mechanisms of inactivation and implications for management of patients
    • Kennedy RD, Quinn JE, Johnston PG, Harkin DP. BRCA1: mechanisms of inactivation and implications for management of patients. Lancet 2002;360:1007-1014.
    • (2002) Lancet , vol.360 , pp. 1007-1014
    • Kennedy, R.D.1    Quinn, J.E.2    Johnston, P.G.3    Harkin, D.P.4
  • 63
    • 0035959804 scopus 로고    scopus 로고
    • BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents
    • Mullan PB, Quinn JE, Gilmore PR, et al. BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents. Oncogene 2001;20:6123-6131.
    • (2001) Oncogene , vol.20 , pp. 6123-6131
    • Mullan, P.B.1    Quinn, J.E.2    Gilmore, P.R.3
  • 64
    • 0036836565 scopus 로고    scopus 로고
    • Subcellular localization of the BRCA1 gene product in mitotic cells
    • Lotti LV, Ottini L, D'Amico C, et al. Subcellular localization of the BRCA1 gene product in mitotic cells. Genes Chromosomes Cancer 2002;35:193-203.
    • (2002) Genes Chromosomes Cancer , vol.35 , pp. 193-203
    • Lotti, L.V.1    Ottini, L.2    D'Amico, C.3
  • 66
    • 0030920914 scopus 로고    scopus 로고
    • The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin
    • DOI 10.1074/jbc.272.22.14041
    • Potapova O, Haghighi A, Bost F, et al. The Jun Kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin. J Biol Chem 1997; 272:14041-14044. (Pubitemid 27232804)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.22 , pp. 14041-14044
    • Potapova, O.1    Haghighi, A.2    Bost, F.3    Liu, C.4    Birrer, M.J.5    Gjerset, R.6    Mercola, D.7
  • 67
    • 0035807219 scopus 로고    scopus 로고
    • Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway
    • DOI 10.1038/sj.onc.1204812
    • Lafarge S, Sylvain V, Ferrara M, Bignon YJ. Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway. Oncogene 2001;20:6597-6606. (Pubitemid 32980286)
    • (2001) Oncogene , vol.20 , Issue.45 , pp. 6597-6606
    • Lafarge, S.1    Sylvain, V.2    Ferrara, M.3    Bignon, Y.-J.4
  • 69
    • 68549116746 scopus 로고    scopus 로고
    • Increased BRCA1 mRNA: An independent prognostic variable in completely resected chemo-naïve non-small cell lung cancer (NSCLC) patienst (p)
    • abstract 7551
    • Rosell R, Jassem E, Skrzypski M, et al. Increased BRCA1 mRNA: an independent prognostic variable in completely resected chemo-naïve non-small cell lung cancer (NSCLC) patienst (p). J Clin Oncol 2007; 25(supp):abstract 7551.
    • (2007) J Clin Oncol , vol.25 , Issue.SUPPL.
    • Rosell, R.1    Jassem, E.2    Skrzypski, M.3
  • 72
    • 32144446618 scopus 로고    scopus 로고
    • MZF1 possesses a repressively regulatory function in ERCC1 expression
    • DOI 10.1016/j.bcp.2005.12.015, PII S0006295205008440
    • Yan QW, Reed E, Zhong XS, Thornton K, Guo Y, Yu JJ. MZF1possesses a repressively regulatory function in ERCC1 expression. Biochem Pharmacol 2006;71:761-771. (Pubitemid 43208832)
    • (2006) Biochemical Pharmacology , vol.71 , Issue.6 , pp. 761-771
    • Yan, Q.-W.1    Reed, E.2    Zhong, X.-S.3    Thornton, K.4    Guo, Y.5    Yu, J.J.6
  • 73
    • 8344280283 scopus 로고    scopus 로고
    • Sp1/Sp3 and the myeloid zinc finger gene MZF1 regulate the human N-cadherin promoter in osteoblasts
    • DOI 10.1016/j.yexcr.2004.08.028, PII S0014482704005075
    • Le Mee S, Fromigue O, Marie PJ. Sp1/Sp3 and the myeloid zinc finger gene MZF1 regulate the human N-cadherin promoter in osteoblasts. Exp Cell Res 2005;302:129-142. (Pubitemid 39482374)
    • (2005) Experimental Cell Research , vol.302 , Issue.1 , pp. 129-142
    • Le Mee, S.1    Fromigue, O.2    Marie, P.J.3
  • 75
    • 33645733588 scopus 로고    scopus 로고
    • N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1
    • Alexander NR, Tran NL, Rekapally H, Summers CE, Glackin C, Heimark RL. N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1. Cancer Res 2006;66:3365-3369.
    • (2006) Cancer Res , vol.66 , pp. 3365-3369
    • Alexander, N.R.1    Tran, N.L.2    Rekapally, H.3    Summers, C.E.4    Glackin, C.5    Heimark, R.L.6
  • 77
    • 32244449328 scopus 로고    scopus 로고
    • The involvement of thioredoxin and thioredoxin binding protein-2 on cellular proliferation and aging process
    • DOI 10.1196/annals.1323.002
    • Yoshida T, Nakamura H, Masutani H, Yodoi J. The involvement of thioredoxin and thioredoxin binding protein-2 on cellular proliferation and aging process. Ann N Y Acad Sci 2005;1055:1-12. (Pubitemid 43211660)
    • (2005) Annals of the New York Academy of Sciences , vol.1055 , pp. 1-12
    • Yoshida, T.1    Nakamura, H.2    Masutani, H.3    Yodoi, J.4
  • 79
    • 3042665933 scopus 로고    scopus 로고
    • Gene expression as a predictive marker of outcome in stage IIB-IIIA-IIIB non-small cell lung cancer after induction gemcitabine-based chemotherapy followed by resectional surgery
    • DOI 10.1158/1078-0432.CCR-040006
    • Rosell R, Felip E, Taron M, et al. Gene expression as a predictive marker of outcome in stage IIB-IIIA-IIIB non-small cell lung cancer after induction gemcitabine-based chemotherapy followed by resectional surgery. Clin Cancer Res 2004;10:4215s- 4219s. (Pubitemid 38812449)
    • (2004) Clinical Cancer Research , vol.10 , Issue.12
    • Rosell, R.1    Felip, E.2    Taron, M.3    Majo, J.4    Mendez, P.5    Sanchez-Ronco, M.6    Queralt, C.7    Sanchez, J.J.8    Maestre, J.9
  • 80
    • 21844437071 scopus 로고    scopus 로고
    • SCAN1 mutant Tdp1 accumulates the enzyme-DNA intermediate and causes camptothecin hypersensitivity
    • DOI 10.1038/sj.emboj.7600694
    • Interthal H, Chen HJ, Kehl-Fie TE, Zotzmann J, Leppard JB, Champoux JJ. SCAN1 mutant Tdp1 accumulates the enzyme-DNA intermediate and causes camptothecin hypersensitivity. Embo J 2005;24: 2224-2233. (Pubitemid 40961806)
    • (2005) EMBO Journal , vol.24 , Issue.12 , pp. 2224-2233
    • Interthal, H.1    Chen, H.J.2    Kehl-Fie, T.E.3    Zotzmann, J.4    Leppard, J.B.5    Champoux, J.J.6
  • 82
    • 33847326382 scopus 로고    scopus 로고
    • Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer
    • DOI 10.1016/j.lungcan.2006.10.019, PII S0169500206006039
    • Liu C, Zhou S, Begum S, et al. Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer. Lung Cancer 2007;55:303-311. (Pubitemid 46329184)
    • (2007) Lung Cancer , vol.55 , Issue.3 , pp. 303-311
    • Liu, C.1    Zhou, S.2    Begum, S.3    Sidransky, D.4    Westra, W.H.5    Brock, M.6    Califano, J.A.7
  • 83
    • 27944446105 scopus 로고    scopus 로고
    • Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
    • DOI 10.1016/j.molcel.2005.10.033, PII S1097276505017284
    • Yoeli-Lerner M, Yiu GK, Rabinovitz I, Erhardt P, Jauliac S, Toker A. Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol Cell 2005;20:539-550. (Pubitemid 41668639)
    • (2005) Molecular Cell , vol.20 , Issue.4 , pp. 539-550
    • Yoeli-Lerner, M.1    Yiu, G.K.2    Rabinovitz, I.3    Erhardt, P.4    Jauliac, S.5    Toker, A.6
  • 84
    • 0036308285 scopus 로고    scopus 로고
    • The role of NFAT transcription factors in integrin-mediated carcinoma invasion
    • DOI 10.1038/ncb816
    • Jauliac S, Lopez-Rodriguez C, Shaw LM, Brown LF, Rao A, Toker A. The role of NFAT transcription factors in integrin-mediated carcinoma invasion. Nat Cell Biol 2002;4:540-544. (Pubitemid 34752442)
    • (2002) Nature Cell Biology , vol.4 , Issue.7 , pp. 540-544
    • Jauliac, S.1    Lopez-Rodriguez, C.2    Shaw, L.M.3    Brown, L.F.4    Rao, A.5    Toker, A.6
  • 86
    • 33646409883 scopus 로고    scopus 로고
    • 2BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance
    • Chabalier C, Lamare C, Racca C, Privat M, Valette A, Larminat F. 2BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance. Cell Cycle 2006;5:1001-1007.
    • (2006) Cell Cycle , vol.5 , pp. 1001-1007
    • Chabalier, C.1    Lamare, C.2    Racca, C.3    Privat, M.4    Valette, A.5    Larminat, F.6
  • 87
    • 0036141441 scopus 로고    scopus 로고
    • Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival
    • Shichiri M, Yoshinaga K, Hisatomi H, Sugihara K, Hirata Y. Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival. Cancer Res 2002;62:13-17. (Pubitemid 34073977)
    • (2002) Cancer Research , vol.62 , Issue.1 , pp. 13-17
    • Shichiri, M.1    Yoshinaga, K.2    Hisatomi, H.3    Sugihara, K.4    Hirata, Y.5
  • 89
    • 37549025804 scopus 로고    scopus 로고
    • BRCA1 mRNA expression levels predict for overall survival on ovarian cancer after chemotherapy
    • Quinn J, James C, Stewart G, et al. BRCA1 mRNA expression levels predict for overall survival on ovarian cancer after chemotherapy. Clin Cancer Res 2007;13:7413-7420.
    • (2007) Clin Cancer Res , vol.13 , pp. 7413-7420
    • Quinn, J.1    James, C.2    Stewart, G.3
  • 90
    • 59449107777 scopus 로고    scopus 로고
    • Spanish customized adjuvant trial (SCAT) based on BRCA1 mRNA levels
    • abstract 7533
    • Cobo M, Massuti T, Morán T, et al. Spanish customized adjuvant trial (SCAT) based on BRCA1 mRNA levels. J Clin Oncol 2008;26(supp): abstract 7533.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Cobo, M.1    Massuti, T.2    Morán, T.3
  • 91
    • 68549128241 scopus 로고    scopus 로고
    • Influence of XPG mRNA levels on the effect of BRCA1 mRNA levels in pronosis of early Non-Small Cell Lung Cancer (NSCLC)
    • abstract 7545
    • Bartolucci R, Botia M, Mendez P, et al. Influence of XPG mRNA levels on the effect of BRCA1 mRNA levels in pronosis of early non-small cell lung cancer (NSCLC). J Clin Oncol 2008;26(supp): abstract 7545.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Bartolucci, R.1    Botia, M.2    Mendez, P.3
  • 96
  • 97
    • 16544393675 scopus 로고    scopus 로고
    • Resistance to microtubuletargeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization
    • Dumuntet C, Jaffrezou JP, Tsuchiya E, et al. Resistance to microtubuletargeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization. Bull Cancer 2004;91: E81-E112.
    • (2004) Bull Cancer , vol.91
    • Dumuntet, C.1    Jaffrezou, J.P.2    Tsuchiya, E.3
  • 99
    • 0027484720 scopus 로고
    • Removal of β(III) isotype enhances taxol induced microtubule assembly
    • Lu Q, Luduena RF. Removal of beta III isotype enhances taxol induced microtubule assembly. Cell Struct Funct 1993;18:173-182. (Pubitemid 23307472)
    • (1993) Cell Structure and Function , vol.18 , Issue.3 , pp. 173-182
    • Lu, Q.1    Luduena, R.F.2
  • 100
    • 0025058099 scopus 로고
    • Increased microtubule assembly in bovine brain tubulin lacking the type III isotype of β-tubulin
    • Banerjee A, Roach MC, Trcka P, Luduena RF. Increased microtubule assembly in bovine brain tubulin lacking the type III isotype of beta-tubulin. J Biol Chem 1990;265:1794-1799. (Pubitemid 20049015)
    • (1990) Journal of Biological Chemistry , vol.265 , Issue.3 , pp. 1794-1799
    • Banerjee, A.1    Roach, M.C.2    Trcka, P.3    Luduena, R.F.4
  • 102
    • 14544302690 scopus 로고    scopus 로고
    • Expression of class III beta tubulin in non-small cell lung cancer is correlated with resistance to taxane chemotherapy
    • Dumontet C, Isaac S, Souquet PJ, et al. Expression of class III beta tubulin in non-small cell lung cancer is correlated with resistance to taxane chemotherapy. Bull Cancer 2005;92:E25-E30.
    • (2005) Bull Cancer , vol.92
    • Dumontet, C.1    Isaac, S.2    Souquet, P.J.3
  • 103
    • 30344437279 scopus 로고    scopus 로고
    • Class III β-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel
    • DOI 10.1158/1535-7163.MCT-05-0244
    • Séve P, Mackey J, Isaac S, et al. Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel. Mol Cancer Ther 2005;4:2001-2007. (Pubitemid 43056983)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.12 , pp. 2001-2007
    • Seve, P.1    Mackey, J.2    Isaac, S.3    Tredan, O.4    Souquet, P.-J.5    Perol, M.6    Lai, R.7    Voloch, A.8    Dumontet, C.9
  • 107
    • 68549092183 scopus 로고    scopus 로고
    • Prognostic value of class III b-tubulin (TUBB3) in operable non-small cell lung cancer (NSCLC) and predictive value for adjuvant cisplatin-based chemotherapy (CT): A validation study on three randomized trials
    • abstract 7506
    • Reiman T, Seve P, Vataire A, et al. Prognostic value of class III b-tubulin (TUBB3) in operable non-small cell lung cancer (NSCLC) and predictive value for adjuvant cisplatin-based chemotherapy (CT): a validation study on three randomized trials. J Clin Oncol 2008; 26(supp):abstract 7506.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Reiman, T.1    Seve, P.2    Vataire, A.3
  • 108
    • 18344377030 scopus 로고    scopus 로고
    • The p53 pathway: Positive and negative feedback loops
    • Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene 2005;24:2899-2908.
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1    Levine, A.J.2
  • 110
    • 0033765491 scopus 로고    scopus 로고
    • Prognostic significance of p53 alterations in patients with non-small cell lung cancer: A meta-analysis
    • Mitsudomi T, Hamajima N, Ogawa M, Takahashi T. Prognostic significance of p53 alterations in patients with non-small cell lung cancer: a meta-analysis. Clin Cancer Res 2000;6:4055-4063. (Pubitemid 30807100)
    • (2000) Clinical Cancer Research , vol.6 , Issue.10 , pp. 4055-4063
    • Mitsudomi, T.1    Hamajima, N.2    Ogawa, M.3    Takahashi, T.4
  • 113
    • 0032855959 scopus 로고    scopus 로고
    • K-ras oncogene mutation as a prognostic marker in non-small cell lung cancer: A combined analysis of 881 cases
    • DOI 10.1093/carcin/20.8.1507
    • Huncharek M, Muscat J, Geschwind JF. K-ras oncogene mutation as a prognostic marker in non-small cell lung cancer: a combined analysis of 881 cases. Carcinogenesis 1999;20:1507-1510. (Pubitemid 29385437)
    • (1999) Carcinogenesis , vol.20 , Issue.8 , pp. 1507-1510
    • Huncharek, M.1    Muscat, J.2    Geschwind, J.-F.3
  • 114
    • 23244461458 scopus 로고    scopus 로고
    • Selective reporting biases in cancer prognostic factor studies
    • Kyzas PA, Loizou KT, Ioannidis JP. Selective reporting biases in cancer prognostic factor studies. J Natl Cancer Inst 2005;97:1043-1055.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1043-1055
    • Kyzas, P.A.1    Loizou, K.T.2    Ioannidis, J.P.3
  • 115
    • 33747074100 scopus 로고    scopus 로고
    • Immunohistochemical markers of prognosis in non-small cell lung cancer: A review and proposal for a multiphase approach to marker evaluation
    • DOI 10.1136/jcp.2005.031351
    • Zhu CQ, Shih W, Ling CH, Tsao MS. Immunohistochemical markers of prognosis in non-small cell lung cancer: a review and proposal for amultiphase approach to marker evaluation. J Clin Pathol 2006;59:790-800. (Pubitemid 44211740)
    • (2006) Journal of Clinical Pathology , vol.59 , Issue.8 , pp. 790-800
    • Zhu, C.-Q.1    Shih, W.2    Ling, C.-H.3    Tsao, M.-S.4
  • 117
    • 11244344381 scopus 로고    scopus 로고
    • P53: Traffic cop at the crossroads of DNA repair and recombination
    • DOI 10.1038/nrm1546
    • Sengupta S, Harris CC. p53: traffic cop at the crossroads of DNA repair and recombination. Nat Rev Mol Cell Biol 2005;6:44-55. (Pubitemid 40064898)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.1 , pp. 44-55
    • Sengupta, S.1    Harris, C.C.2
  • 119
    • 0036258111 scopus 로고    scopus 로고
    • The IARC TP53 database: New online mutation analysis and recommendations to users
    • DOI 10.1002/humu.10081
    • Olivier M, Eeles R, Hollstein M, Khan MA, Harris CC, Hainaut P. The IARC Tp53 database: new online mutation analysis and recommendations to users. Hum Mutat 2002;19:607-614. (Pubitemid 34556481)
    • (2002) Human Mutation , vol.19 , Issue.6 , pp. 607-614
    • Olivier, M.1    Eeles, R.2    Hollstein, M.3    Khan, M.A.4    Harris, C.C.5    Hainaut, P.6
  • 120
    • 0028299342 scopus 로고
    • P53 in tumour pathology: Can we trust immunohistochemistry?- Revisited!
    • Hall PA, Lane DP. p53 in tumour pathology: can we trust immunohistochemistry?- revisited! J Pathol 1994;172:1-4.
    • (1994) J Pathol , vol.172 , pp. 1-4
    • Hall, P.A.1    Lane, D.P.2
  • 121
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1994;54:4855-4878. (Pubitemid 24289415)
    • (1994) Cancer Research , vol.54 , Issue.18 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 122
    • 0345824732 scopus 로고    scopus 로고
    • Cell cycle regulatory functions of the human oncoprotein MDM2
    • Deb SP. Cell cycle regulatory functions of the human oncoprotein MDM2. Mol Cancer Res 2003;1:1009-1016.
    • (2003) Mol Cancer Res , vol.1 , pp. 1009-1016
    • Deb, S.P.1
  • 123
    • 0030825813 scopus 로고    scopus 로고
    • P53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding
    • Midgley CA, Lane DP. p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding. Oncogene 1997;15:1179-1189.
    • (1997) Oncogene , vol.15 , pp. 1179-1189
    • Midgley, C.A.1    Lane, D.P.2
  • 124
    • 16644396297 scopus 로고    scopus 로고
    • Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: An alternative pathway to non-small-cell lung cancer
    • Wang YC, Lin RK, Tan YH, Chen JT, Chen CY, Wang YC. Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: an alternative pathway to non-small-cell lung cancer. J Clin Oncol 2005;23:154-164.
    • (2005) J Clin Oncol , vol.23 , pp. 154-164
    • Wang, Y.C.1    Lin, R.K.2    Tan, Y.H.3    Chen, J.T.4    Chen, C.Y.5    Wang, Y.C.6
  • 125
    • 0033118475 scopus 로고    scopus 로고
    • Apoptosis, p53, and tumor cell sensitivity to anticancer agents
    • Brown JM, Wouters BG. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res 1999;59:1391-1399.
    • (1999) Cancer Res , vol.59 , pp. 1391-1399
    • Brown, J.M.1    Wouters, B.G.2
  • 126
    • 0037309326 scopus 로고    scopus 로고
    • Tumor suppression by Ink4a-Arf: Progress and puzzles
    • Lowe SW, Sherr CJ. Tumor suppression by Ink4a-Arf: progress and puzzles. Curr Opin Gen Dev 2003;13:77-83.
    • (2003) Curr Opin Gen Dev , vol.13 , pp. 77-83
    • Lowe, S.W.1    Sherr, C.J.2
  • 127
    • 0030913266 scopus 로고    scopus 로고
    • Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard
    • Fan S, Chang JK, Smith ML, Duba D, Fornace AJ Jr, O'Connor PM. Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard. Oncogene 1997;14:2127-2136. (Pubitemid 27248224)
    • (1997) Oncogene , vol.14 , Issue.18 , pp. 2127-2136
    • Fan, S.1    Chang, J.K.2    Smith, M.L.3    Duba, D.4    Fornace Jr., A.J.5    O'Connor, P.M.6
  • 129
    • 68549118425 scopus 로고    scopus 로고
    • Patterns of co-expression of ERCC1 and p27 in resected non-small cell lung cancer by immunohistochemistry
    • abstract 7595
    • Rekhtman N, Azzoli CG, Kris MG, et al. Patterns of co-expression of ERCC1 and p27 in resected non-small cell lung cancer by immunohistochemistry. J Clin Oncol 2008;26(supp):abstract 7595.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Rekhtman, N.1    Azzoli, C.G.2    Kris, M.G.3
  • 130
    • 0345357773 scopus 로고    scopus 로고
    • Gene Silencing in Cancer in Association with Promoter Hypermethylation
    • DOI 10.1056/NEJMra023075
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003;349:2042-2054. (Pubitemid 37448928)
    • (2003) New England Journal of Medicine , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 131
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer- A mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer- a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006;6:107-116.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 132
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • Esteller M, Corn PG, Baylin SB, Herman JG. A gene hypermethylation profile of human cancer. Cancer Res 2001;61:3225-3229. (Pubitemid 32695003)
    • (2001) Cancer Research , vol.61 , Issue.8 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 133
    • 40849124009 scopus 로고    scopus 로고
    • DNA methylation markers and early recurrence in stage I lung cancer
    • Brock M, Hooker C, Ota-Machida E, et al. DNA methylation markers and early recurrence in stage I lung cancer. N Engl J Med 2008;358: 1118-1128.
    • (2008) N Engl J Med , vol.358 , pp. 1118-1128
    • Brock, M.1    Hooker, C.2    Ota-Machida, E.3
  • 137
    • 33745700196 scopus 로고    scopus 로고
    • Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer
    • Machida EO, Brock MV, Hooker CM, et al. Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer. Cancer Res 2006;66:6210-6218.
    • (2006) Cancer Res , vol.66 , pp. 6210-6218
    • Machida, E.O.1    Brock, M.V.2    Hooker, C.M.3
  • 138
    • 1642564204 scopus 로고    scopus 로고
    • Pulmonary resection in octogenarians with stage I nonsmall cell lung cancer: A 22-year experience
    • Brock MV, Kim MP, Hooker CM, et al. Pulmonary resection in octogenarians with stage I nonsmall cell lung cancer: a 22-year experience. Ann Thorac Surg 2004;77:271-277.
    • (2004) Ann Thorac Surg , vol.77 , pp. 271-277
    • Brock, M.V.1    Kim, M.P.2    Hooker, C.M.3
  • 141
    • 33846187641 scopus 로고    scopus 로고
    • Aberrant promoter methylation profile and association with survival in patients with non-small cell lung cancer
    • DOI 10.1158/1078-0432.CCR-06-0894
    • Gu J, Berman D, Lu C, et al. Aberrant promoter methylation profile and association with survival in patients with non-small cell lung cancer. Clin Cancer Res 2006;12:7329-7338. (Pubitemid 46095405)
    • (2006) Clinical Cancer Research , vol.12 , Issue.24 , pp. 7329-7338
    • Gu, J.1    Berman, D.2    Lu, C.3    Wistuba, I.I.4    Roth, J.A.5    Frazier, M.6    Spitz, M.R.7    Wu, X.8
  • 144
    • 33645521023 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort
    • Belinsky SA, Liechty KC, Gentry FD, et al. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res 2006;66:3338-3344.
    • (2006) Cancer Res , vol.66 , pp. 3338-3344
    • Belinsky, S.A.1    Liechty, K.C.2    Gentry, F.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.