-
1
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
-
2
-
-
19744368302
-
Cancer of the ovary
-
Cannistra SA. Cancer of the ovary. N Engl J Med 2004;351:2519-29.
-
(2004)
N Engl J Med
, vol.351
, pp. 2519-2529
-
-
Cannistra, S.A.1
-
3
-
-
0142178215
-
Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2
-
King MC, Marks JH, Mandell JB. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 2003;302:643-6.
-
(2003)
Science
, vol.302
, pp. 643-646
-
-
King, M.C.1
Marks, J.H.2
Mandell, J.B.3
-
4
-
-
29144509766
-
BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases
-
Pal T, Permuth-Wey J, Betts JA, et al. BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases. Cancer 2005;104:2807-16.
-
(2005)
Cancer
, vol.104
, pp. 2807-2816
-
-
Pal, T.1
Permuth-Wey, J.2
Betts, J.A.3
-
5
-
-
4344665689
-
The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer
-
McCoy ML, Mueller CR, Roskelley CD. The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer. Reprod Biol Endocrinol 2003;1:72.
-
(2003)
Reprod Biol Endocrinol
, vol.1
, pp. 72
-
-
McCoy, M.L.1
Mueller, C.R.2
Roskelley, C.D.3
-
6
-
-
0034256069
-
Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers
-
Russell PA, Pharoah PD, De Foy K, et al. Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers. Int J Cancer 2000;87:317-21.
-
(2000)
Int J Cancer
, vol.87
, pp. 317-321
-
-
Russell, P.A.1
Pharoah, P.D.2
De Foy, K.3
-
7
-
-
1142311552
-
Expression of BRCA1 protein in benign, borderline, and malignant epithelial ovarian neoplasms and its relationship to methylation and allelic loss of the BRCA1 gene
-
Wang C, Horiuchi A, Imai T, et al. Expression of BRCA1 protein in benign, borderline, and malignant epithelial ovarian neoplasms and its relationship to methylation and allelic loss of the BRCA1 gene. J Pathol 2004;202:215-3.
-
(2004)
J Pathol
, vol.202
, pp. 215-213
-
-
Wang, C.1
Horiuchi, A.2
Imai, T.3
-
8
-
-
0034307160
-
BRCA1 promoter region hypermethylation in ovarian carcinoma: A population-based study
-
Baldwin RL, Nemeth E, Tran H, et al. BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study. Cancer Res 2000;60:5329-33.
-
(2000)
Cancer Res
, vol.60
, pp. 5329-5333
-
-
Baldwin, R.L.1
Nemeth, E.2
Tran, H.3
-
9
-
-
0037099625
-
Epigenetic factors controlling the BRCA1 and BRCA2 genes in sporadic ovarian cancer
-
Chan KY, Ozcelik H, Cheung AN, Ngan HY, Khoo US. Epigenetic factors controlling the BRCA1 and BRCA2 genes in sporadic ovarian cancer. Cancer Res 2002;62:4151-6.
-
(2002)
Cancer Res
, vol.62
, pp. 4151-4156
-
-
Chan, K.Y.1
Ozcelik, H.2
Cheung, A.N.3
Ngan, H.Y.4
Khoo, U.S.5
-
10
-
-
0038147067
-
BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells
-
Tassone P, Tagliaferri P, Perricelli A, et al. BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells. Br J Cancer 2003;88:1285-91.
-
(2003)
Br J Cancer
, vol.88
, pp. 1285-1291
-
-
Tassone, P.1
Tagliaferri, P.2
Perricelli, A.3
-
11
-
-
0141954010
-
BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis
-
Quinn JE, Kennedy RD, Mullan PB, et al. BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis. Cancer Res 2003;63:6221-8.
-
(2003)
Cancer Res
, vol.63
, pp. 6221-6228
-
-
Quinn, J.E.1
Kennedy, R.D.2
Mullan, P.B.3
-
12
-
-
0035807219
-
Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway
-
Lafarge S, Sylvain V, Ferrara M, Bignon YJ. Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway. Oncogene 2001;20:6597-606.
-
(2001)
Oncogene
, vol.20
, pp. 6597-6606
-
-
Lafarge, S.1
Sylvain, V.2
Ferrara, M.3
Bignon, Y.J.4
-
14
-
-
0043130465
-
The effect of loss of brca1 on the sensitivity to anticancer agents in p53-deficient cells
-
Fedier A, Steiner RA, Schwarz VA, Lenherr L, Haller U, Fink D. The effect of loss of brca1 on the sensitivity to anticancer agents in p53-deficient cells. Int J Oncol 2003;22:1169-73.
-
(2003)
Int J Oncol
, vol.22
, pp. 1169-1173
-
-
Fedier, A.1
Steiner, R.A.2
Schwarz, V.A.3
Lenherr, L.4
Haller, U.5
Fink, D.6
-
15
-
-
14644435658
-
Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS
-
Sgagias MK, Wagner KU, Hamik B, et al. Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS. Cell Cycle 2004;3:1451-6.
-
(2004)
Cell Cycle
, vol.3
, pp. 1451-1456
-
-
Sgagias, M.K.1
Wagner, K.U.2
Hamik, B.3
-
16
-
-
0036341143
-
A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer
-
Chappuis PO, Goffin J, Wong N, et al. A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer. J Med Genet 2002;39:608-10.
-
(2002)
J Med Genet
, vol.39
, pp. 608-610
-
-
Chappuis, P.O.1
Goffin, J.2
Wong, N.3
-
17
-
-
26244453280
-
Risk of breast cancer recurrence and contralateral breast cancer in relation to BRCA1 and BRCA2 mutation status following breast-conserving surgery and radiotherapy
-
Kirova YM, Stoppa-Lyonnet D, Savignoni A, Sigal-Zafrani B, Fabre N, Fourquet A. Risk of breast cancer recurrence and contralateral breast cancer in relation to BRCA1 and BRCA2 mutation status following breast-conserving surgery and radiotherapy. Eur J Cancer 2005;41:2304-11.
-
(2005)
Eur J Cancer
, vol.41
, pp. 2304-2311
-
-
Kirova, Y.M.1
Stoppa-Lyonnet, D.2
Savignoni, A.3
Sigal-Zafrani, B.4
Fabre, N.5
Fourquet, A.6
-
18
-
-
33645359491
-
BRCA1 expression in a large series of sporadic ovarian carcinomas: A Gynecologic Oncology Group study
-
Thrall M, Gallion HH, Kryscio R, Kapali M, Armstrong DK, DeLoia JA. BRCA1 expression in a large series of sporadic ovarian carcinomas: a Gynecologic Oncology Group study. Int J Gynecol Cancer 2006;1:166-71.
-
(2006)
Int J Gynecol Cancer
, vol.1
, pp. 166-171
-
-
Thrall, M.1
Gallion, H.H.2
Kryscio, R.3
Kapali, M.4
Armstrong, D.K.5
DeLoia, J.A.6
-
19
-
-
19544379515
-
BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer
-
Taron M, Rosell R, Felip E, et al. BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer. Hum Mol Genet 2004;13:2443-9.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2443-2449
-
-
Taron, M.1
Rosell, R.2
Felip, E.3
-
20
-
-
0035959804
-
2/M cell cycle arrest in response to antimicrotubule agents
-
2/M cell cycle arrest in response to antimicrotubule agents. Oncogene 2001;20:6123-31.
-
(2001)
Oncogene
, vol.20
, pp. 6123-6131
-
-
Mullan, P.B.1
Quinn, J.E.2
Gilmore, P.M.3
-
21
-
-
33646409883
-
BRCA1 down-regulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance
-
Chabalier C, Lamare C, Racca C, Privat M, Valette A, Larminat F. BRCA1 down-regulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance. Cell Cycle 2006;5:1001-7.
-
(2006)
Cell Cycle
, vol.5
, pp. 1001-1007
-
-
Chabalier, C.1
Lamare, C.2
Racca, C.3
Privat, M.4
Valette, A.5
Larminat, F.6
-
22
-
-
32144439074
-
Loss of BRCA1 expression may predict shorter time-to-progression in metastatic breast cancer patients treated with taxanes
-
Kurebayashi J, Yamamoto Y, Kurosumi M, et al. Loss of BRCA1 expression may predict shorter time-to-progression in metastatic breast cancer patients treated with taxanes. Anticancer Res 2006;26:695-701.
-
(2006)
Anticancer Res
, vol.26
, pp. 695-701
-
-
Kurebayashi, J.1
Yamamoto, Y.2
Kurosumi, M.3
-
23
-
-
0032521537
-
-
Husain A, He G, Venkatraman ES, Spriggs DR. BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II). Cancer Res 1998;58:1120-3.
-
Husain A, He G, Venkatraman ES, Spriggs DR. BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II). Cancer Res 1998;58:1120-3.
-
-
-
-
24
-
-
0036546218
-
Dominant-negative activity of a Brca1 truncationmutant: Effects on proliferation, tumorigenicity in vivo, and chemosensitivity in a mouse ovarian cancer cell line
-
Sylvain V, Lafarge S, Bignon YJ. Dominant-negative activity of a Brca1 truncationmutant: effects on proliferation, tumorigenicity in vivo, and chemosensitivity in a mouse ovarian cancer cell line. Int J Oncol 2002;20:845-53.
-
(2002)
Int J Oncol
, vol.20
, pp. 845-853
-
-
Sylvain, V.1
Lafarge, S.2
Bignon, Y.J.3
-
25
-
-
0038031592
-
Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1
-
Zhou C, Smith JL, Liu J. Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1. Oncogene 2003;22:2396-404.
-
(2003)
Oncogene
, vol.22
, pp. 2396-2404
-
-
Zhou, C.1
Smith, J.L.2
Liu, J.3
-
26
-
-
10544220023
-
Clinical and pathological features of ovarian cancer in women with germ-line mutations of BRCA1
-
Rubin SC, Benjamin I, Behbakht K, et al. Clinical and pathological features of ovarian cancer in women with germ-line mutations of BRCA1. N Engl J Med 1996;335:1413-6.
-
(1996)
N Engl J Med
, vol.335
, pp. 1413-1416
-
-
Rubin, S.C.1
Benjamin, I.2
Behbakht, K.3
-
27
-
-
0037403380
-
Improved survival in women with BRCA-associated ovarian carcinoma
-
Cass I, Baldwin RL, Varkey T, Moslehi R, Narod SA, Karlan BY. Improved survival in women with BRCA-associated ovarian carcinoma. Cancer 2003;97:2187-95.
-
(2003)
Cancer
, vol.97
, pp. 2187-2195
-
-
Cass, I.1
Baldwin, R.L.2
Varkey, T.3
Moslehi, R.4
Narod, S.A.5
Karlan, B.Y.6
-
28
-
-
0034469046
-
Increased cell survival by inhibition of BRCA1using an antisense approach in an estrogen responsive ovarian carcinoma cell line
-
Annab LA, Hawkins RE, Solomon G, Barrett JC, Afshari CA. Increased cell survival by inhibition of BRCA1using an antisense approach in an estrogen responsive ovarian carcinoma cell line. Breast Cancer Res 2000;2:139-48.
-
(2000)
Breast Cancer Res
, vol.2
, pp. 139-148
-
-
Annab, L.A.1
Hawkins, R.E.2
Solomon, G.3
Barrett, J.C.4
Afshari, C.A.5
-
29
-
-
10644254600
-
Development and applications of a real-time quantitative RT-PCR method (QRT-PCR) for BRCA1 mRNA
-
Kroupis C, Stathopoulou A, Zygalaki E, Ferekidou L, Talieri M, Lianidou ES. Development and applications of a real-time quantitative RT-PCR method (QRT-PCR) for BRCA1 mRNA. Clin Biochem 2005;38:50-7.
-
(2005)
Clin Biochem
, vol.38
, pp. 50-57
-
-
Kroupis, C.1
Stathopoulou, A.2
Zygalaki, E.3
Ferekidou, L.4
Talieri, M.5
Lianidou, E.S.6
-
30
-
-
33847035558
-
BRCA1, a potential predictive biomarker in the treatment of breast cancer
-
James CR, Quinn JE, Mullan PB, Johnston PG, Harkin DP. BRCA1, a potential predictive biomarker in the treatment of breast cancer. Oncologist 2007;12:142-50.
-
(2007)
Oncologist
, vol.12
, pp. 142-150
-
-
James, C.R.1
Quinn, J.E.2
Mullan, P.B.3
Johnston, P.G.4
Harkin, D.P.5
-
31
-
-
0024489926
-
Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors
-
Geisinger KR, Kute TE, Pettenati MJ, et al. Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors. Cancer 1989;63:280-8.
-
(1989)
Cancer
, vol.63
, pp. 280-288
-
-
Geisinger, K.R.1
Kute, T.E.2
Pettenati, M.J.3
-
32
-
-
0021683409
-
Characterization of a xenograft model of human ovarian carcinoma which produces ascites and intraabdominal carcinomatosis inmice
-
Hamilton TC, Young RC, Louie KG, et al. Characterization of a xenograft model of human ovarian carcinoma which produces ascites and intraabdominal carcinomatosis inmice. Cancer Res 1984;44:5286-90.
-
(1984)
Cancer Res
, vol.44
, pp. 5286-5290
-
-
Hamilton, T.C.1
Young, R.C.2
Louie, K.G.3
-
33
-
-
33749482498
-
A mouse model for the molecular characterization of brca1-associated ovarian carcinoma
-
Xing D, Orsulic S. A mouse model for the molecular characterization of brca1-associated ovarian carcinoma. Cancer Res 2006;66:8949-53.
-
(2006)
Cancer Res
, vol.66
, pp. 8949-8953
-
-
Xing, D.1
Orsulic, S.2
-
34
-
-
33845644738
-
Conditional inactivation of brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes
-
Clark-Knowles KV, Garson K, Jonkers J, Vanderhyden BC. Conditional inactivation of brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes. Exp Cell Res 2007;313:133-45.
-
(2007)
Exp Cell Res
, vol.313
, pp. 133-145
-
-
Clark-Knowles, K.V.1
Garson, K.2
Jonkers, J.3
Vanderhyden, B.C.4
-
35
-
-
33845464255
-
Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions
-
Bartz SR, Zhang Z, Burchard J, et al. Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions. Mol Cell Biol 2006;26:9377-86.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9377-9386
-
-
Bartz, S.R.1
Zhang, Z.2
Burchard, J.3
-
36
-
-
33847304077
-
BRCA1-A good predictive marker of drug sensitivity in breast cancer treatment?
-
Mullan PB, Gorski JJ, Harkin DP. BRCA1-A good predictive marker of drug sensitivity in breast cancer treatment? Biochim Biophys Acta 2006;2:205-16.
-
(2006)
Biochim Biophys Acta
, vol.2
, pp. 205-216
-
-
Mullan, P.B.1
Gorski, J.J.2
Harkin, D.P.3
-
37
-
-
0034600109
-
Clinicopathologic features of BRCA-linked and sporadic ovarian cancer
-
Boyd J, Sonoda Y, Federici MG, et al. Clinicopathologic features of BRCA-linked and sporadic ovarian cancer. JAMA 2000;283:2260-5.
-
(2000)
JAMA
, vol.283
, pp. 2260-2265
-
-
Boyd, J.1
Sonoda, Y.2
Federici, M.G.3
-
38
-
-
0037080115
-
Effect of BRCA mutations on the length of survival in epithelial ovarian tumors
-
Ben David Y, Chetrit A, Hirsh-Yechezkel G, et al. Effect of BRCA mutations on the length of survival in epithelial ovarian tumors. J Clin Oncol 2002;20:463-6.
-
(2002)
J Clin Oncol
, vol.20
, pp. 463-466
-
-
Ben David, Y.1
Chetrit, A.2
Hirsh-Yechezkel, G.3
-
39
-
-
0037368187
-
Increased expression of BRCA1 mRNA predicts favorable response to anthracycline-containing chemotherapy in breast cancers
-
Egawa C, Motomura K, Miyoshi Y, et al. Increased expression of BRCA1 mRNA predicts favorable response to anthracycline-containing chemotherapy in breast cancers. Breast Cancer Res Treat 2003;78:45-50.
-
(2003)
Breast Cancer Res Treat
, vol.78
, pp. 45-50
-
-
Egawa, C.1
Motomura, K.2
Miyoshi, Y.3
-
40
-
-
9744263911
-
The role of BRCA1 in the cellular response to chemotherapy
-
Kennedy RD, Quinn JE, Mullan PB, Johnston PG, Harkin DP. The role of BRCA1 in the cellular response to chemotherapy. J Natl Cancer Inst 2004;96:1659-68.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1659-1668
-
-
Kennedy, R.D.1
Quinn, J.E.2
Mullan, P.B.3
Johnston, P.G.4
Harkin, D.P.5
-
41
-
-
0142053372
-
Current status of taxane and platinum-based chemotherapy in ovarian cancer
-
McGuire WP III. Current status of taxane and platinum-based chemotherapy in ovarian cancer. J Clin Oncol 2003;21:133-5.
-
(2003)
J Clin Oncol
, vol.21
, pp. 133-135
-
-
McGuire III, W.P.1
-
42
-
-
0034600305
-
Randomized intergroup trial of cisplatin-paclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: Three-year results
-
Piccart MJ, Bertelsen K, James K, et al. Randomized intergroup trial of cisplatin-paclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: three-year results. J Natl Cancer Inst 2000;92:699-708.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 699-708
-
-
Piccart, M.J.1
Bertelsen, K.2
James, K.3
|