The R1 component of mammalian ribonucleotide reductase has malignancy-suppressing activity as demonstrated by gene transfer experiments

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 24, 1997, Pages 13181-13186

  Fan, Huizhou ^a   Huang, Aiping ^a   Villegas, Cristy ^a   Wright, Jim A ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; RIBONUCLEOTIDE REDUCTASE;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; COLONY FORMATION; GENE ACTIVATION; GENE OVEREXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LUNG METASTASIS; MALIGNANT TRANSFORMATION; NONHUMAN; ONCOGENE; ONCOGENE MYC; ONCOGENE RAS; PRIORITY JOURNAL;

ANIMALS; CELL ADHESION; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; GENE TRANSFER TECHNIQUES; GENES, RAS; HUMANS; MICE; MICE, INBRED C3H; NEOPLASM METASTASIS; OLIGONUCLEOTIDES, ANTISENSE; RECOMBINANT PROTEINS; RIBONUCLEOTIDE REDUCTASES; TRANSFECTION;

ANIMALIA; MAMMALIA;

EID: 0030720867     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.24.13181     Document Type: Article

References (39)

1. Lewis, W. H., Kuzik, B. A. & Wright, J. A. (1978) J. Cell Physiol. 94, 287-298.
2. Reichard, P. (1993) Science 260, 1773-1777.
3. Wright, J. A. (1989) Int. Encyclop. Pharmacol. Therapeut. 128, 89-111.
4. Tonin, P. N., Stallings, R. L., Carman, M. D., Bertino, J. R., Wright, J. A., Srinivasan, P. R. & Lewis, W. H. (1987) Cytogenet. Cell Genet. 45, 102-108.
5. Wright, J. A., Chan, A. K., Choy, B. K., Hurta, R. A. R., McClarty, G. A. & Tagger, A. Y. (1990) Biochem. Cell. Biol. 68, 1364-1371.
6. McClarty, G. A., Chan, A. K., Choy, B. K. & Wright, J. A. (1990) J. Biol. Chem. 265, 7539-7547.
7. Davis, R., Thelander, M., Mann, G. J., Behravan, G., Soucy, F., Beaulieu, P., Lavallee, P., Gräslund, A. & Thelander, L. (1994) J. Biol. Chem. 269, 23171-23176.
8. Choy, B. K., McClarty, G. A., Chan, A. K., Thelander, L. & Wright, J. A. (1988) Cancer Res. 48, 2029-2035.
9. Eriksson, S., Gräslund, A., Skog, A., Thelander, L. & Tribukait, B. (1984) J. Biol. Chem. 259, 11695-11700.
10. Björklund, S., Skog, S., Tribukait, B. & Thelander, L. (1990) Biochemistry 29, 5452-5458.
11. Hurta, R. A. R. & Wright, J. A. (1992) J. Biol. Chem. 267, 7066-7071.
12. Weber, G. (1983) Cancer Res. 43, 3466-3492.
13. Wright, J. A., McClarty, G. A., Lewis, W. H. & Srinivasan, P. R. in (1989) Drug Resistance in Mammalian Cells, ed. Gupta, R. S. (CRC, Boca Raton, FL), Vol. 1, pp. 15-27.
14. Saeki, T., Takashashi, T., Okabe, M., Furuya, A., Hanai, N., Yamagami, K, Mandai, K., Moriwaki, S., Doihara, H., Takashima, S. & Salomon, D. S. (1995) Int. J. Oncol. 6, 523-533.
15. Jensen, R. A., Page, D. L. & Holt, J. T. (1994) Proc. Natl. Acad. Sci. USA 91, 9257-9261.
16. Amara, F. M., Sun, J. & Wright, J. A. (1996) J. Biol. Chem. 271, 20126-20131.
17. Chen, F. Y., Amara, F. M. & Wright, J. A. (1993) EMBO J. 12, 3977-3986.
18. Amara, F. M., Chen, F. Y. & Wright, J. A. (1995) Nucleic Acids Res. 23, 1461-1467.
19. Hurta, R. A. R., Samuel, S. K., Greenberg, A. H. & Wright, J. A. (1991) J. Biol. Chem. 266, 24097-24100.
20. Fan, H., Villegas, C. & Wright J. A. (1996) Proc. Natl. Acad. Sci. USA 93, 13036-14040.
21. Kozak, M. (1987) Nucleic Acids Res. 20, 8125-8148.
22. Thelander, L. & Berg, P. (1986) Mol. Cell. Biol. 6, 3433-3442.
23. Miller, A. D., Miller, D. G., Garcia, J. V. & Lynch, C. M. (1993) Methods Enzymol. 217, 581-599.
24. Fan, H., Villegas, C. & Wright, J. A. (1996) FEBS Lett. 382, 145-148.
25. Egan, S. E., McClarty, G. A., Jarolim, L., Wright, J. A., Spiro, I., Hager, G. & Greenberg, A. H. (1987) Mol. Cell. Biol. 7, 830-837.
26. Taylor, W. R., Egan, S. E., Mowat, M., Greenberg, A. H. & Wright, J. A. (1992) Oncogene 7, 1383-1390.
27. Kempe, T. D., Swaryl, E. A., Bruist, M. & Stark, G. R. (1976) Cell 9, 541-550.
28. Leonhardt, U., Page, A. W., Weier, H.-U. & Bestor, T. H. Cell 71, 865-873.
29. Goding, J. W. (1978) J. Immunol. Methods 20, 241-253.
30. Mann, G. J., Gräslund, A., Ochiai, E.-I., Ingermarson, R. & Thelander, L. (1991) Biochemistry 30, 1939-1947.
31. Wright, J. A., Turley, E. A. & Greenberg, A. H. (1993) Crit. Rev. Oncog. 4, 473-492.
32. Huang, A., Jin, H., Taylor, W. R. & Wright, J. A. (1995) Int. J. Oncol. 7, 57-63.
33. MacDonald, N. J., De La Rosa, A. & Steeg, P. S. (1995) Eur. J. Cancer 31A, 1096-1100.
34. Welch, D. R., Chen, P., Miele, M. E., McGary, C. T., Bower, J. M., Stanbridge, E. J. & Weissman, B. E. (1994) Oncogene 9, 255-262.
35. Mader, R. M., Schmidt, W., Rizovski, B., Sedivy, R., Steger, G. G., Jakesz, R., Rainer, H. & Mueller, M. W. (1996) Proceedings of the Eighty-Seventh Annual Meeting, American Association of Cancer Research, Vol. 37, p. 547 (abstr.).
36. Wright, J. A. & Anazodo, M. (1995) Cancer J. 8, 185-189.
37. Levine, A. J. (1997) Cell 88, 323-331.
38. Connell-Crowley, L., Harper, J. W. & Doodrich, D. W. (1997) Mol. Biol. Cell 5, 287-301.
39. Bookstein, R., Shew, J. Y., Chen, P. L., Scully, P. & Lee, W.-H. (1990) Science 247, 712-715.