Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding

Journal of Medicinal Chemistry

Volumn 52, Issue 15, 2009, Pages 4923-4935

  Ehrlich, Katharina ^a   Gotz, Angela ^a   Bollinger, Stefan ^a   Tschammer, Nuska ^a   Bettinetti, Laura ^a   Harterich, Steffen ^a   Hubner, Harald ^a   Lanig, Harald ^a   Gmeiner, Peter ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; ASPARTIC ACID; BENZENE DERIVATIVE; BETA 2 ADRENERGIC RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; HETEROCYCLIC COMPOUND; HISTIDINE; INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; RADIOLIGAND; RECEPTOR SUBTYPE; DOPAMINE 1 RECEPTOR; LIGAND; PHENYLPIPERAZINE; SPIPERONE;

ANIMAL CELL; ARTICLE; CRYSTAL STRUCTURE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; GENETIC CONSERVATION; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR MODEL; MOLECULAR PROBE; NONHUMAN; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL; CRICETULUS; HAMSTER; METABOLISM; RADIOASSAY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PIPERAZINES; RADIOLIGAND ASSAY; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; SPIPERONE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 68549110381     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900690y     Document Type: Article

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