Dopamine D4/D2 receptor selectivity is determined by a divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments

Molecular Pharmacology

Volumn 56, Issue 6, 1999, Pages 1116-1126

  Simpson, Merrill M ^a   Ballesteros, Juan A ^a,b   Chiappa, Victor ^a   Chen, Jiayun ^a   Suehiro, Makiko ^a   Hartman, Deborah S ^c,e   Godel, Thierry ^c   Snyder, Lenore A ^d,f   Sakmar, Thomas P ^d   Javitch, Jonathan A ^a,g  

^a Columbia Univ Coll Phys Surgs ^*  (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

^d ROCKEFELLER UNIVERSITY   (United States)

^e Astra Arcus USA Inc   (United States)

^f Linguagen Corp   (United States)

^g Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATECHOLAMINE RELEASE; COMPETITIVE INHIBITION; DRUG RECEPTOR BINDING; EXTRACELLULAR MATRIX; LIGAND BINDING; MEMBRANE BINDING; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; SCHIZOPHRENIA;

EID: 0032723795     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.6.1116     Document Type: Article

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