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Volumn 52, Issue 9, 2009, Pages 1899-1912

Microarray analysis of genes with impaired insulin regulation in the skeletal muscle of type 2 diabetic patients indicates the involvement of basic helix-loop-helix domain-containing, class B, 2 protein (BHLHB2)

Author keywords

BHLHB2; Hyperinsulinaemic euglycaemic clamp; Insulin; Skeletal muscle; Transcription factors; Transcription network; Type 2 diabetes

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BHLHB2 PROTEIN; CREATINE KINASE; ESTROGEN RECEPTOR; FORKHEAD TRANSCRIPTION FACTOR; HIGH MOBILITY GROUP A1A PROTEIN; HYPOXIA INDUCIBLE FACTOR 1BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; NUCLEAR FACTOR I; THYROID HORMONE RECEPTOR BETA; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR GATA 5; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR MASH1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 68449087392     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1442-4     Document Type: Article
Times cited : (19)

References (41)
  • 1
    • 0042570843 scopus 로고    scopus 로고
    • Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
    • A Virkamaki K Ueki CR Kahn 1999 Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance J Clin Invest 103 931 943
    • (1999) J Clin Invest , vol.103 , pp. 931-943
    • Virkamaki, A.1    Ueki, K.2    Kahn, C.R.3
  • 2
    • 45549083411 scopus 로고    scopus 로고
    • Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo
    • DK Coletta B Balas AO Chavez 2008 Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo Am J Physiol 294 E910 E917
    • (2008) Am J Physiol , vol.294
    • Coletta, D.K.1    Balas, B.2    Chavez, A.O.3
  • 3
    • 0038724906 scopus 로고    scopus 로고
    • Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp
    • S Rome K Clement R Rabasa-Lhoret 2003 Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp J Biol Chem 278 18063 18068
    • (2003) J Biol Chem , vol.278 , pp. 18063-18068
    • Rome, S.1    Clement, K.2    Rabasa-Lhoret, R.3
  • 4
    • 35248874438 scopus 로고    scopus 로고
    • The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle
    • X Wu J Wang X Cui 2007 The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle Endocrine 31 5 17
    • (2007) Endocrine , vol.31 , pp. 5-17
    • Wu, X.1    Wang, J.2    Cui, X.3
  • 5
    • 42149146205 scopus 로고    scopus 로고
    • Microarray analysis of insulin-regulated gene expression in the liver: The use of transgenic mice co-expressing insulin-siRNA and human IDE as an animal model
    • S Jee D Hwang S Seo 2007 Microarray analysis of insulin-regulated gene expression in the liver: the use of transgenic mice co-expressing insulin-siRNA and human IDE as an animal model Int J Mol Med 20 829 835
    • (2007) Int J Mol Med , vol.20 , pp. 829-835
    • Jee, S.1    Hwang, D.2    Seo, S.3
  • 6
    • 0029859045 scopus 로고    scopus 로고
    • Regulation of gene expression by insulin
    • RM O'Brien DK Granner 1996 Regulation of gene expression by insulin Physiol Rev 76 1109 1161
    • (1996) Physiol Rev , vol.76 , pp. 1109-1161
    • O'Brien, R.M.1    Granner, D.K.2
  • 7
    • 0034693259 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
    • TF Osborne 2000 Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action J Biol Chem 275 32379 32382
    • (2000) J Biol Chem , vol.275 , pp. 32379-32382
    • Osborne, T.F.1
  • 8
    • 53249156226 scopus 로고    scopus 로고
    • Regulation of insulin-response element binding protein-1 in obesity and diabetes: Potential role in impaired insulin-induced gene transcription
    • J Chahal CC Chen MJ Rane 2008 Regulation of insulin-response element binding protein-1 in obesity and diabetes: potential role in impaired insulin-induced gene transcription Endocrinology 149 4829 4836
    • (2008) Endocrinology , vol.149 , pp. 4829-4836
    • Chahal, J.1    Chen, C.C.2    Rane, M.J.3
  • 10
    • 0027303280 scopus 로고
    • Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion
    • PH Andersen S Lund H Vestergaard S Junker BB Kahn O Pedersen 1993 Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion J Clin Endocrinol Metab 77 27 32
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 27-32
    • Andersen, P.H.1    Lund, S.2    Vestergaard, H.3    Junker, S.4    Kahn, B.B.5    Pedersen, O.6
  • 11
    • 0035029812 scopus 로고    scopus 로고
    • Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes
    • PH Ducluzeau N Perretti M Laville 2001 Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes Diabetes 50 1134 1142
    • (2001) Diabetes , vol.50 , pp. 1134-1142
    • Ducluzeau, P.H.1    Perretti, N.2    Laville, M.3
  • 12
    • 0028842531 scopus 로고
    • Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients
    • H Vestergaard C Bjorbaek T Hansen FS Larsen DK Granner O Pedersen 1995 Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients J Clin Invest 96 2639 2645
    • (1995) J Clin Invest , vol.96 , pp. 2639-2645
    • Vestergaard, H.1    Bjorbaek, C.2    Hansen, T.3    Larsen, F.S.4    Granner, D.K.5    Pedersen, O.6
  • 13
    • 0037477855 scopus 로고    scopus 로고
    • Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
    • ME Patti AJ Butte S Crunkhorn 2003 Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1 Proc Natl Acad Sci U S A 100 8466 8471
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8466-8471
    • Patti, M.E.1    Butte, A.J.2    Crunkhorn, S.3
  • 14
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • VK Mootha CM Lindgren KF Eriksson 2003 PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes Nat Genet 34 267 273
    • (2003) Nat Genet , vol.34 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3
  • 15
    • 21344471947 scopus 로고    scopus 로고
    • Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; Their gene expressions are regulated by multiple extracellular stimuli
    • K Yamada K Miyamoto 2005 Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their gene expressions are regulated by multiple extracellular stimuli Front Biosci 10 3151 3171
    • (2005) Front Biosci , vol.10 , pp. 3151-3171
    • Yamada, K.1    Miyamoto, K.2
  • 16
    • 0030037364 scopus 로고    scopus 로고
    • Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle
    • M Laville D Auboeuf Y Khalfallah N Vega JP Riou H Vidal 1996 Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle J Clin Invest 98 43 49
    • (1996) J Clin Invest , vol.98 , pp. 43-49
    • Laville, M.1    Auboeuf, D.2    Khalfallah, Y.3    Vega, N.4    Riou, J.P.5    Vidal, H.6
  • 17
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Y Benjamini Y Hochberg 1995 Controlling the false discovery rate: a practical and powerful approach to multiple testing J R Stat Soc: Ser B (Methodol) 57 289 300
    • (1995) J R Stat Soc: Ser B (Methodol) , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 18
    • 21444443478 scopus 로고    scopus 로고
    • MatInspector and beyond: Promoter analysis based on transcription factor binding sites
    • K Cartharius K Frech K Grote 2005 MatInspector and beyond: promoter analysis based on transcription factor binding sites Bioinformatics (Oxford, England) 21 2933 2942
    • (2005) Bioinformatics (Oxford, England) , vol.21 , pp. 2933-2942
    • Cartharius, K.1    Frech, K.2    Grote, K.3
  • 19
    • 57049172674 scopus 로고    scopus 로고
    • Microarrays analysis of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle
    • S Rome V Lecomte E Meugnier 2008 Microarrays analysis of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle Physiol Genomics 34 327 337
    • (2008) Physiol Genomics , vol.34 , pp. 327-337
    • Rome, S.1    Lecomte, V.2    Meugnier, E.3
  • 20
    • 33746847084 scopus 로고    scopus 로고
    • An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes
    • K Le Brigand R Russell C Moreilhon 2006 An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes Nucleic Acids Res 34 e87
    • (2006) Nucleic Acids Res , vol.34 , pp. 87
    • Le Brigand, K.1    Russell, R.2    Moreilhon, C.3
  • 21
    • 0025779431 scopus 로고
    • HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1
    • N Nomura MJ Zhao T Nagase 1991 HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1 J Biol Chem 266 8590 8594
    • (1991) J Biol Chem , vol.266 , pp. 8590-8594
    • Nomura, N.1    Zhao, M.J.2    Nagase, T.3
  • 22
    • 20444477132 scopus 로고    scopus 로고
    • Transcriptional regulatory networks in lipid metabolism control ABCA1 expression
    • G Schmitz T Langmann 2005 Transcriptional regulatory networks in lipid metabolism control ABCA1 expression Biochim Biophys Acta 1735 1 19
    • (2005) Biochim Biophys Acta , vol.1735 , pp. 1-19
    • Schmitz, G.1    Langmann, T.2
  • 23
    • 0032169214 scopus 로고    scopus 로고
    • Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT
    • E Zelzer Y Levy C Kahana BZ Shilo M Rubinstein B Cohen 1998 Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT EMBO J 17 5085 5094
    • (1998) EMBO J , vol.17 , pp. 5085-5094
    • Zelzer, E.1    Levy, Y.2    Kahana, C.3    Shilo, B.Z.4    Rubinstein, M.5    Cohen, B.6
  • 24
    • 0028865103 scopus 로고
    • DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins
    • HI Swanson WK Chan CA Bradfield 1995 DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins J Biol Chem 270 26292 26302
    • (1995) J Biol Chem , vol.270 , pp. 26292-26302
    • Swanson, H.I.1    Chan, W.K.2    Bradfield, C.A.3
  • 25
    • 0037195939 scopus 로고    scopus 로고
    • Stra13 homodimers repress transcription through class B E-box elements
    • B St-Pierre G Flock E Zacksenhaus SE Egan 2002 Stra13 homodimers repress transcription through class B E-box elements J Biol Chem 277 46544 46551
    • (2002) J Biol Chem , vol.277 , pp. 46544-46551
    • St-Pierre, B.1    Flock, G.2    Zacksenhaus, E.3    Egan, S.E.4
  • 26
    • 40949114964 scopus 로고    scopus 로고
    • Up-regulation of hypertonicity-activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1
    • F Klaus M Palmada R Lindner 2008 Up-regulation of hypertonicity-activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1 J Physiol 586 1539 1547
    • (2008) J Physiol , vol.586 , pp. 1539-1547
    • Klaus, F.1    Palmada, M.2    Lindner, R.3
  • 27
    • 0031938843 scopus 로고    scopus 로고
    • Insulin-induced hexokinase II expression is reduced in obesity and NIDDM
    • M Pendergrass J Koval C Vogt 1998 Insulin-induced hexokinase II expression is reduced in obesity and NIDDM Diabetes 47 387 394
    • (1998) Diabetes , vol.47 , pp. 387-394
    • Pendergrass, M.1    Koval, J.2    Vogt, C.3
  • 28
    • 0033029101 scopus 로고    scopus 로고
    • Defective regulation of phosphatidylinositol-3-kinase gene expression in skeletal muscle and adipose tissue of non-insulin-dependent diabetes mellitus patients
    • F Andreelli M Laville PH Ducluzeau 1999 Defective regulation of phosphatidylinositol-3-kinase gene expression in skeletal muscle and adipose tissue of non-insulin-dependent diabetes mellitus patients Diabetologia 42 358 364
    • (1999) Diabetologia , vol.42 , pp. 358-364
    • Andreelli, F.1    Laville, M.2    Ducluzeau, P.H.3
  • 29
    • 58549084978 scopus 로고    scopus 로고
    • Alterations of insulin signaling in type 2 diabetes: A review of the current evidence from humans
    • S Frojdo H Vidal L Pirola 2009 Alterations of insulin signaling in type 2 diabetes: a review of the current evidence from humans Biochim Biophys Acta 1792 83 92
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 83-92
    • Frojdo, S.1    Vidal, H.2    Pirola, L.3
  • 30
    • 0038321436 scopus 로고    scopus 로고
    • Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes
    • K Bouzakri M Roques P Gual 2003 Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes Diabetes 52 1319 1325
    • (2003) Diabetes , vol.52 , pp. 1319-1325
    • Bouzakri, K.1    Roques, M.2    Gual, P.3
  • 31
    • 33749342069 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance: Serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: The two sides of a coin
    • B Draznin 2006 Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin Diabetes 55 2392 2397
    • (2006) Diabetes , vol.55 , pp. 2392-2397
    • Draznin, B.1
  • 32
    • 56149119808 scopus 로고    scopus 로고
    • Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose
    • I Dahlman M Vaxillaire M Nilsson 2008 Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose Pharmacogenet Genomics 18 967 975
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 967-975
    • Dahlman, I.1    Vaxillaire, M.2    Nilsson, M.3
  • 33
    • 33748919513 scopus 로고    scopus 로고
    • NFkappaB and its inhibitor IkappaB in relation to type 2 diabetes and its microvascular and atherosclerotic complications
    • M Romzova D Hohenadel K Kolostova 2006 NFkappaB and its inhibitor IkappaB in relation to type 2 diabetes and its microvascular and atherosclerotic complications Hum Immunol 67 706 713
    • (2006) Hum Immunol , vol.67 , pp. 706-713
    • Romzova, M.1    Hohenadel, D.2    Kolostova, K.3
  • 34
    • 22544482628 scopus 로고    scopus 로고
    • Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
    • D Foti E Chiefari M Fedele 2005 Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice Nat Med 11 765 773
    • (2005) Nat Med , vol.11 , pp. 765-773
    • Foti, D.1    Chiefari, E.2    Fedele, M.3
  • 35
    • 47749120570 scopus 로고    scopus 로고
    • Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping
    • K Iizuka Y Horikawa 2008 Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping Biochem Biophys Res Commun 374 95 100
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 95-100
    • Iizuka, K.1    Horikawa, Y.2
  • 36
    • 0042733340 scopus 로고    scopus 로고
    • Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway
    • K Yamada H Kawata Z Shou T Mizutani T Noguchi K Miyamoto 2003 Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway J Biol Chem 278 30719 30724
    • (2003) J Biol Chem , vol.278 , pp. 30719-30724
    • Yamada, K.1    Kawata, H.2    Shou, Z.3    Mizutani, T.4    Noguchi, T.5    Miyamoto, K.6
  • 37
    • 0031852665 scopus 로고    scopus 로고
    • Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
    • A Krook RA Roth XJ Jiang JR Zierath H Wallberg-Henriksson 1998 Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects Diabetes 47 1281 1286
    • (1998) Diabetes , vol.47 , pp. 1281-1286
    • Krook, A.1    Roth, R.A.2    Jiang, X.J.3    Zierath, J.R.4    Wallberg-Henriksson, H.5
  • 38
    • 56649103933 scopus 로고    scopus 로고
    • Stra13/DEC1 and DEC2 inhibit sterol regulatory element binding protein-1c in a hypoxia-inducible factor-dependent mechanism
    • SM Choi HJ Cho H Cho KH Kim JB Kim H Park 2008 Stra13/DEC1 and DEC2 inhibit sterol regulatory element binding protein-1c in a hypoxia-inducible factor-dependent mechanism Nucleic Acids Res 36 6372 6385
    • (2008) Nucleic Acids Res , vol.36 , pp. 6372-6385
    • Choi, S.M.1    Cho, H.J.2    Cho, H.3    Kim, K.H.4    Kim, J.B.5    Park, H.6
  • 39
    • 0032705145 scopus 로고    scopus 로고
    • MEF2: A transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation
    • FJ Naya E Olson 1999 MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation Curr Opin Cell Biol 11 683 688
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 683-688
    • Naya, F.J.1    Olson, E.2
  • 40
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • DE Kelley J He EV Menshikova VB Ritov 2002 Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes Diabetes 51 2944 2950
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 41
    • 42549089170 scopus 로고    scopus 로고
    • Muscular response and adaptation to diabetes mellitus
    • Z Sun L Liu N Liu Y Liu 2008 Muscular response and adaptation to diabetes mellitus Front Biosci 13 4765 4794
    • (2008) Front Biosci , vol.13 , pp. 4765-4794
    • Sun, Z.1    Liu, L.2    Liu, N.3    Liu, Y.4


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