-
1
-
-
0042570843
-
Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
-
A Virkamaki K Ueki CR Kahn 1999 Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance J Clin Invest 103 931 943
-
(1999)
J Clin Invest
, vol.103
, pp. 931-943
-
-
Virkamaki, A.1
Ueki, K.2
Kahn, C.R.3
-
2
-
-
45549083411
-
Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo
-
DK Coletta B Balas AO Chavez 2008 Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo Am J Physiol 294 E910 E917
-
(2008)
Am J Physiol
, vol.294
-
-
Coletta, D.K.1
Balas, B.2
Chavez, A.O.3
-
3
-
-
0038724906
-
Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp
-
S Rome K Clement R Rabasa-Lhoret 2003 Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp J Biol Chem 278 18063 18068
-
(2003)
J Biol Chem
, vol.278
, pp. 18063-18068
-
-
Rome, S.1
Clement, K.2
Rabasa-Lhoret, R.3
-
4
-
-
35248874438
-
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle
-
X Wu J Wang X Cui 2007 The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle Endocrine 31 5 17
-
(2007)
Endocrine
, vol.31
, pp. 5-17
-
-
Wu, X.1
Wang, J.2
Cui, X.3
-
5
-
-
42149146205
-
Microarray analysis of insulin-regulated gene expression in the liver: The use of transgenic mice co-expressing insulin-siRNA and human IDE as an animal model
-
S Jee D Hwang S Seo 2007 Microarray analysis of insulin-regulated gene expression in the liver: the use of transgenic mice co-expressing insulin-siRNA and human IDE as an animal model Int J Mol Med 20 829 835
-
(2007)
Int J Mol Med
, vol.20
, pp. 829-835
-
-
Jee, S.1
Hwang, D.2
Seo, S.3
-
6
-
-
0029859045
-
Regulation of gene expression by insulin
-
RM O'Brien DK Granner 1996 Regulation of gene expression by insulin Physiol Rev 76 1109 1161
-
(1996)
Physiol Rev
, vol.76
, pp. 1109-1161
-
-
O'Brien, R.M.1
Granner, D.K.2
-
7
-
-
0034693259
-
Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
-
TF Osborne 2000 Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action J Biol Chem 275 32379 32382
-
(2000)
J Biol Chem
, vol.275
, pp. 32379-32382
-
-
Osborne, T.F.1
-
8
-
-
53249156226
-
Regulation of insulin-response element binding protein-1 in obesity and diabetes: Potential role in impaired insulin-induced gene transcription
-
J Chahal CC Chen MJ Rane 2008 Regulation of insulin-response element binding protein-1 in obesity and diabetes: potential role in impaired insulin-induced gene transcription Endocrinology 149 4829 4836
-
(2008)
Endocrinology
, vol.149
, pp. 4829-4836
-
-
Chahal, J.1
Chen, C.C.2
Rane, M.J.3
-
10
-
-
0027303280
-
Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion
-
PH Andersen S Lund H Vestergaard S Junker BB Kahn O Pedersen 1993 Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion J Clin Endocrinol Metab 77 27 32
-
(1993)
J Clin Endocrinol Metab
, vol.77
, pp. 27-32
-
-
Andersen, P.H.1
Lund, S.2
Vestergaard, H.3
Junker, S.4
Kahn, B.B.5
Pedersen, O.6
-
11
-
-
0035029812
-
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes
-
PH Ducluzeau N Perretti M Laville 2001 Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes Diabetes 50 1134 1142
-
(2001)
Diabetes
, vol.50
, pp. 1134-1142
-
-
Ducluzeau, P.H.1
Perretti, N.2
Laville, M.3
-
12
-
-
0028842531
-
Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients
-
H Vestergaard C Bjorbaek T Hansen FS Larsen DK Granner O Pedersen 1995 Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients J Clin Invest 96 2639 2645
-
(1995)
J Clin Invest
, vol.96
, pp. 2639-2645
-
-
Vestergaard, H.1
Bjorbaek, C.2
Hansen, T.3
Larsen, F.S.4
Granner, D.K.5
Pedersen, O.6
-
13
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
ME Patti AJ Butte S Crunkhorn 2003 Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1 Proc Natl Acad Sci U S A 100 8466 8471
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
-
14
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
VK Mootha CM Lindgren KF Eriksson 2003 PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes Nat Genet 34 267 273
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
-
15
-
-
21344471947
-
Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; Their gene expressions are regulated by multiple extracellular stimuli
-
K Yamada K Miyamoto 2005 Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their gene expressions are regulated by multiple extracellular stimuli Front Biosci 10 3151 3171
-
(2005)
Front Biosci
, vol.10
, pp. 3151-3171
-
-
Yamada, K.1
Miyamoto, K.2
-
16
-
-
0030037364
-
Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle
-
M Laville D Auboeuf Y Khalfallah N Vega JP Riou H Vidal 1996 Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle J Clin Invest 98 43 49
-
(1996)
J Clin Invest
, vol.98
, pp. 43-49
-
-
Laville, M.1
Auboeuf, D.2
Khalfallah, Y.3
Vega, N.4
Riou, J.P.5
Vidal, H.6
-
17
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Y Benjamini Y Hochberg 1995 Controlling the false discovery rate: a practical and powerful approach to multiple testing J R Stat Soc: Ser B (Methodol) 57 289 300
-
(1995)
J R Stat Soc: Ser B (Methodol)
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
18
-
-
21444443478
-
MatInspector and beyond: Promoter analysis based on transcription factor binding sites
-
K Cartharius K Frech K Grote 2005 MatInspector and beyond: promoter analysis based on transcription factor binding sites Bioinformatics (Oxford, England) 21 2933 2942
-
(2005)
Bioinformatics (Oxford, England)
, vol.21
, pp. 2933-2942
-
-
Cartharius, K.1
Frech, K.2
Grote, K.3
-
19
-
-
57049172674
-
Microarrays analysis of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle
-
S Rome V Lecomte E Meugnier 2008 Microarrays analysis of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle Physiol Genomics 34 327 337
-
(2008)
Physiol Genomics
, vol.34
, pp. 327-337
-
-
Rome, S.1
Lecomte, V.2
Meugnier, E.3
-
20
-
-
33746847084
-
An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes
-
K Le Brigand R Russell C Moreilhon 2006 An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes Nucleic Acids Res 34 e87
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 87
-
-
Le Brigand, K.1
Russell, R.2
Moreilhon, C.3
-
21
-
-
0025779431
-
HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1
-
N Nomura MJ Zhao T Nagase 1991 HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1 J Biol Chem 266 8590 8594
-
(1991)
J Biol Chem
, vol.266
, pp. 8590-8594
-
-
Nomura, N.1
Zhao, M.J.2
Nagase, T.3
-
22
-
-
20444477132
-
Transcriptional regulatory networks in lipid metabolism control ABCA1 expression
-
G Schmitz T Langmann 2005 Transcriptional regulatory networks in lipid metabolism control ABCA1 expression Biochim Biophys Acta 1735 1 19
-
(2005)
Biochim Biophys Acta
, vol.1735
, pp. 1-19
-
-
Schmitz, G.1
Langmann, T.2
-
23
-
-
0032169214
-
Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT
-
E Zelzer Y Levy C Kahana BZ Shilo M Rubinstein B Cohen 1998 Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT EMBO J 17 5085 5094
-
(1998)
EMBO J
, vol.17
, pp. 5085-5094
-
-
Zelzer, E.1
Levy, Y.2
Kahana, C.3
Shilo, B.Z.4
Rubinstein, M.5
Cohen, B.6
-
24
-
-
0028865103
-
DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins
-
HI Swanson WK Chan CA Bradfield 1995 DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins J Biol Chem 270 26292 26302
-
(1995)
J Biol Chem
, vol.270
, pp. 26292-26302
-
-
Swanson, H.I.1
Chan, W.K.2
Bradfield, C.A.3
-
25
-
-
0037195939
-
Stra13 homodimers repress transcription through class B E-box elements
-
B St-Pierre G Flock E Zacksenhaus SE Egan 2002 Stra13 homodimers repress transcription through class B E-box elements J Biol Chem 277 46544 46551
-
(2002)
J Biol Chem
, vol.277
, pp. 46544-46551
-
-
St-Pierre, B.1
Flock, G.2
Zacksenhaus, E.3
Egan, S.E.4
-
26
-
-
40949114964
-
Up-regulation of hypertonicity-activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1
-
F Klaus M Palmada R Lindner 2008 Up-regulation of hypertonicity-activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1 J Physiol 586 1539 1547
-
(2008)
J Physiol
, vol.586
, pp. 1539-1547
-
-
Klaus, F.1
Palmada, M.2
Lindner, R.3
-
27
-
-
0031938843
-
Insulin-induced hexokinase II expression is reduced in obesity and NIDDM
-
M Pendergrass J Koval C Vogt 1998 Insulin-induced hexokinase II expression is reduced in obesity and NIDDM Diabetes 47 387 394
-
(1998)
Diabetes
, vol.47
, pp. 387-394
-
-
Pendergrass, M.1
Koval, J.2
Vogt, C.3
-
28
-
-
0033029101
-
Defective regulation of phosphatidylinositol-3-kinase gene expression in skeletal muscle and adipose tissue of non-insulin-dependent diabetes mellitus patients
-
F Andreelli M Laville PH Ducluzeau 1999 Defective regulation of phosphatidylinositol-3-kinase gene expression in skeletal muscle and adipose tissue of non-insulin-dependent diabetes mellitus patients Diabetologia 42 358 364
-
(1999)
Diabetologia
, vol.42
, pp. 358-364
-
-
Andreelli, F.1
Laville, M.2
Ducluzeau, P.H.3
-
29
-
-
58549084978
-
Alterations of insulin signaling in type 2 diabetes: A review of the current evidence from humans
-
S Frojdo H Vidal L Pirola 2009 Alterations of insulin signaling in type 2 diabetes: a review of the current evidence from humans Biochim Biophys Acta 1792 83 92
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 83-92
-
-
Frojdo, S.1
Vidal, H.2
Pirola, L.3
-
30
-
-
0038321436
-
Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes
-
K Bouzakri M Roques P Gual 2003 Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes Diabetes 52 1319 1325
-
(2003)
Diabetes
, vol.52
, pp. 1319-1325
-
-
Bouzakri, K.1
Roques, M.2
Gual, P.3
-
31
-
-
33749342069
-
Molecular mechanisms of insulin resistance: Serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: The two sides of a coin
-
B Draznin 2006 Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin Diabetes 55 2392 2397
-
(2006)
Diabetes
, vol.55
, pp. 2392-2397
-
-
Draznin, B.1
-
32
-
-
56149119808
-
Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose
-
I Dahlman M Vaxillaire M Nilsson 2008 Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose Pharmacogenet Genomics 18 967 975
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 967-975
-
-
Dahlman, I.1
Vaxillaire, M.2
Nilsson, M.3
-
33
-
-
33748919513
-
NFkappaB and its inhibitor IkappaB in relation to type 2 diabetes and its microvascular and atherosclerotic complications
-
M Romzova D Hohenadel K Kolostova 2006 NFkappaB and its inhibitor IkappaB in relation to type 2 diabetes and its microvascular and atherosclerotic complications Hum Immunol 67 706 713
-
(2006)
Hum Immunol
, vol.67
, pp. 706-713
-
-
Romzova, M.1
Hohenadel, D.2
Kolostova, K.3
-
34
-
-
22544482628
-
Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
-
D Foti E Chiefari M Fedele 2005 Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice Nat Med 11 765 773
-
(2005)
Nat Med
, vol.11
, pp. 765-773
-
-
Foti, D.1
Chiefari, E.2
Fedele, M.3
-
35
-
-
47749120570
-
Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping
-
K Iizuka Y Horikawa 2008 Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping Biochem Biophys Res Commun 374 95 100
-
(2008)
Biochem Biophys Res Commun
, vol.374
, pp. 95-100
-
-
Iizuka, K.1
Horikawa, Y.2
-
36
-
-
0042733340
-
Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway
-
K Yamada H Kawata Z Shou T Mizutani T Noguchi K Miyamoto 2003 Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway J Biol Chem 278 30719 30724
-
(2003)
J Biol Chem
, vol.278
, pp. 30719-30724
-
-
Yamada, K.1
Kawata, H.2
Shou, Z.3
Mizutani, T.4
Noguchi, T.5
Miyamoto, K.6
-
38
-
-
56649103933
-
Stra13/DEC1 and DEC2 inhibit sterol regulatory element binding protein-1c in a hypoxia-inducible factor-dependent mechanism
-
SM Choi HJ Cho H Cho KH Kim JB Kim H Park 2008 Stra13/DEC1 and DEC2 inhibit sterol regulatory element binding protein-1c in a hypoxia-inducible factor-dependent mechanism Nucleic Acids Res 36 6372 6385
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 6372-6385
-
-
Choi, S.M.1
Cho, H.J.2
Cho, H.3
Kim, K.H.4
Kim, J.B.5
Park, H.6
-
39
-
-
0032705145
-
MEF2: A transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation
-
FJ Naya E Olson 1999 MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation Curr Opin Cell Biol 11 683 688
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 683-688
-
-
Naya, F.J.1
Olson, E.2
-
40
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
DE Kelley J He EV Menshikova VB Ritov 2002 Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes Diabetes 51 2944 2950
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
41
-
-
42549089170
-
Muscular response and adaptation to diabetes mellitus
-
Z Sun L Liu N Liu Y Liu 2008 Muscular response and adaptation to diabetes mellitus Front Biosci 13 4765 4794
-
(2008)
Front Biosci
, vol.13
, pp. 4765-4794
-
-
Sun, Z.1
Liu, L.2
Liu, N.3
Liu, Y.4
|