Up-regulation of hypertonicity-activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1

Journal of Physiology

Volumn 586, Issue 6, 2008, Pages 1539-1547

  Klaus, F ^a   Palmada, M ^a,b   Lindner, R ^a   Laufer, J ^a   Jeyaraj, S ^a   Lang, Florian ^a   Boehmer, C ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; BREFELDIN A; CARRIER PROTEIN; HYPERTONIC SOLUTION; PROTEIN KINASE; PROTEIN KINASE B; REGULATOR PROTEIN; SERUM AND GLUCOCORTICOID INDUCIBLE KINASE 2; SERUM AND GLUCOCORTICOID INDUCIBLE KINASE 3; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM MYOINOSITOL TRANSPORTER 1; TONICITY ENHANCER BINDING PROTEIN; TONICITY RESPONSIVE ENHANCER PROTEIN; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG; CASPASE 2; INOSITOL; PROTEIN SERINE THREONINE KINASE; SGK2 PROTEIN; SGK3 PROTEIN; SMIT1 PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL SURFACE; CELL VOLUME; CONTROLLED STUDY; ENHANCER REGION; FEMALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STABILITY; PROTEIN TRANSPORT; TRANSPORT KINETICS; UPREGULATION; VOLTAGE CLAMP; XENOPUS LAEVIS; CELL MEMBRANE; ENZYME ACTIVITY; MEMBRANE CURRENT; OSMOLARITY; PROTEIN EXPRESSION;

ANIMALS; CELL SIZE; CELLS, CULTURED; IMMEDIATE-EARLY PROTEINS; OOCYTES; OSMOTIC PRESSURE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SYMPORTERS; UP-REGULATION; WATER-ELECTROLYTE BALANCE; XENOPUS LAEVIS;

EID: 40949114964     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.146191     Document Type: Article

References (40)

1. Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P & Hemmings BA (1996). Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15, 6541-6551.
2. +/myo-inositol cotransporter gene (SLC5A3): Molecular cloning and localization to chromosome 21. Genomics 25, 507-513.
3. Bitoun M & Tappaz M (2000). Gene expression of the transporters and biosynthetic enzymes of the osmolytes in astrocyte primary cultures exposed to hyperosmotic conditions. Glia 32, 165-176.
4. Boehmer C, Henke G, Schniepp R, Palmada M, Rothstein JD, Broer S & Lang F (2003). Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B. J Neurochem 86, 1181-1188.
5. Boehmer C, Palmada M, Rajamanickam J, Schniepp R, Amara S & Lang F (2006). Post-translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases. J Neurochem 97, 911-921.
6. Boehmer C, Rajamanickam J, Schniepp R, Kohler K, Wulff P, Kuhl D, Palmada M & Lang F (2005). Regulation of the excitatory amino acid transporter EAAT5 by the serum and glucocorticoid dependent kinases SGK1 and SGK3. Biochem Biophys Res Commun 329, 738-742.
7. + channel cell surface expression. EMBO J 20, 7052-7059.
8. Denkert C, Warskulat U, Hensel F & Haussinger D (1998). Osmolyte strategy in human monocytes and macrophages: Involvement of p38MAPK in hyperosmotic induction of betaine and myoinositol transporters. Arch Biochem Biophys 354, 172-180.
9. Dieter M, Palmada M, Rajamanickam J, Aydin A, Busjahn A, Boehmer C, Luft FC & Lang F (2004). Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. Obes Res 12, 862-870.
10. Ferraris JD, Williams CK, Jung KY, Bedford JJ, Burg MB & Garcia-Perez A (1996). ORE, a eukaryotic minimal essential osmotic response element. The aldose reductase gene in hyperosmotic stress. J Biol Chem 271, 18318-18321.
11. +/myo-inositol cotransporter expressed in Xenopus oocytes. J Membr Biol 143, 103-113.
12. Hou J, Speirs HJ, Seckl JR & Brown RW (2002). Sgk1 gene expression in kidney and its regulation by aldosterone: Spatio-temporal heterogeneity and quantitative analysis. J Am Soc Nephrol 13, 1190-1198.
13. Ito T, Fujio Y, Hirata M, Takatani T, Matsuda T, Muraoka S, Takahashi K & Azuma J (2004). Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells. Biochem J 382, 177-182.
14. Kitamura H, Yamauchi A, Sugiura T, Matsuoka Y, Horio M, Tohyama M, Shimada S, Imai E & Hori M (1998). Inhibition of myo-inositol transport causes acute renal failure with selective medullary injury in the rat. Kidney Int 53, 146-153.
15. Kobayashi T, Deak M, Morrice N & Cohen P (1999). Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. Biochem J 344, 189-197.
16. +/myo-inositol cotransporter, a hypertonicity stress protein. J Biol Chem 267, 6297-6301.
17. Lang F, Bohmer C, Palmada M, Seebohm G, Strutz-Seebohm N & Vallon V (2006). (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms. Physiol Rev 86, 1151-1178.
18. Lang F, Busch GL & Volkl H (1998). The diversity of volume regulatory mechanisms. Cell Physiol Biochem 8, 1-45.
19. Lang F, Volkl H, Woll E & Haussinger D (1991). Mechanisms of cell volume regulation in kidney and liver. Contrib Nephrol 95, 237-245.
20. Maallem S, Berod A, Mutin M, Kwon HM & Tappaz ML (2006 a). Large discrepancies in cellular distribution of the tonicity-induced expression of osmoprotective genes and their regulatory transcription factor TonEBP in rat brain. Neuroscience 142, 355-368.
21. Maallem S, Mutin M, Kwon HM & Tappaz ML (2006 b). Differential cellular distribution of tonicity-induced expression of transcription factor TonEBP in the rat brain following prolonged systemic hypertonicity. Neuroscience 137, 51-71.
22. McCormick JA, Bhalla V, Pao AC & Pearce D (2005). SGK1: A rapid aldosterone-induced regulator of renal sodium reabsorption. Physiology (Bethesda) 20, 134-139.
23. Macknight AD (1988). Principles of cell volume regulation. Ren Physiol Biochem 11, 114-141.
24. Macknight AD, Gordon LG & Purves RD (1994). Problems in the understanding of cell volume regulation. J Exp Zool 268, 80-89.
25. Miyakawa H, Woo SK, Dahl SC, Handler JS & Kwon HM (1999). Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity. Proc Natl Acad Sci U S A 96, 2538-2542.
26. Rajamanickam J, Palmada M, Lang F & Boehmer C (2007). EAAT4 phosphorylation at the SGK1 consensus site is required for transport modulation by the kinase. J Neurochem 102, 858-866.
27. Rim JS, Tanawattanacharoen S, Takenaka M, Handler JS & Kwon HM (1997). The canine sodium/myo-inositol cotransporter gene: Structural organization and characterization of the promoter. Arch Biochem Biophys 341, 193-199.
28. Somero GN (1986). Protons, osmolytes, and fitness of internal milieu for protein function. Am J Physiol Regul Integr Comp Physiol 251, R197-R213.
29. +/myo-inositol cotransport in rat cortical astrocytes. Glia 12, 35-43.
30. Takenaka M, Preston AS, Kwon HM & Handler JS (1994). The tonicity-sensitive element that mediates increased transcription of the betaine transporter gene in response to hypertonic stress. J Biol Chem 269, 29379-29381.
31. Wagner CA, Friedrich B, Setiawan I, Lang F & Broer S (2000). The use of Xenopus laevis oocytes for the functional characterization of heterologously expressed membrane proteins. Cell Physiol Biochem 10, 1-12.
32. Waldegger S, Barth P, Forrest JN Jr, Greger R & Lang F (1998 a). Cloning of sgk serine-threonine protein kinase from shark rectal gland -a gene induced by hypertonicity and secretagogues. Pflugers Arch 436, 575-580.
33. Waldegger S, Barth P, Raber G & Lang F (1997). Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume. Proc Natl Acad Sci U S A 94, 4440-4445.
34. Waldegger S, Steuer S, Risler T, Heidland A, Capasso G, Massry S & Lang F (1998 b). Mechanisms and clinical significance of cell volume regulation. Nephrol Dial Transplant 13, 867-874.
35. Warntges S, Friedrich B, Henke G, Duranton C, Lang PA, Waldegger S, Meyermann R, Kuhl D, Speckmann EJ, Obermuller N, Witzgall R, Mack AF, Wagner HJ, Wagner A, Broer S & Lang F (2002). Cerebral localization and regulation of the cell volume-sensitive serum- and glucocorticoid-dependent kinase SGK1. Pflugers Arch 443, 617-624.
36. Webster MK, Goya L, Ge Y, Maiyar AC & Firestone GL (1993). Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum. Mol Cell Biol 13, 2031-2040.
37. Wiese TJ, Dunlap JA, Conner CE, Grzybowski JA, Lowe WL Jr & Yorek MA (1996). Osmotic regulation of Na-myo-inositol cotransporter mRNA level and activity in endothelial and neural cells. Am J Physiol Cell Physiol 270, C990-C997.
38. Yancey PH, Clark ME, Hand SC, Bowlus RD & Somero GN (1982). Living with water stress: Evolution of osmolyte systems. Science 217, 1214-1222.
39. + channel ROMK1. J Am Soc Nephrol 13, 2823-2830.
40. Zhang F, Warskulat U, Wettstein M & Haussinger D (1996). Identification of betaine as an osmolyte in rat liver macrophages (Kupffer cells). Gastroenterology 110, 1543-1552.