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Volumn 294, Issue 5, 2008, Pages

Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo

Author keywords

Euglycemic hyperinsulinemic clamp; Gene expression; Inflammation; Insulin action; Muscle

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; INSULIN; MESSENGER RNA; PROTEIN FOS; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOSB; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR JUNB; COLORING AGENT; GLUCOSE;

EID: 45549083411     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00607.2007     Document Type: Article
Times cited : (78)

References (44)
  • 2
    • 0035016566 scopus 로고    scopus 로고
    • Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
    • Andersson U, Scarpulla RC. Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol Cell Biol 21: 3738-3749, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 3738-3749
    • Andersson, U.1    Scarpulla, R.C.2
  • 3
    • 33845514376 scopus 로고    scopus 로고
    • Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia
    • Asmann YW, Stump CS, Short KR, Coenen-Schimke JM, Guo Z, Bigelow ML, Nair KS. Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia. Diabetes 55: 3309-3319, 2006.
    • (2006) Diabetes , vol.55 , pp. 3309-3319
    • Asmann, Y.W.1    Stump, C.S.2    Short, K.R.3    Coenen-Schimke, J.M.4    Guo, Z.5    Bigelow, M.L.6    Nair, K.S.7
  • 4
    • 0038547023 scopus 로고    scopus 로고
    • Metabolic and molecular basis of insulin resistance
    • Bajaj M, DeFronzo RA. Metabolic and molecular basis of insulin resistance. J Nucl Cardiol 10: 311-323, 2003.
    • (2003) J Nucl Cardiol , vol.10 , pp. 311-323
    • Bajaj, M.1    DeFronzo, R.A.2
  • 5
    • 33644695097 scopus 로고    scopus 로고
    • Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients
    • Bajaj M, Suraamornkul S, Romanelli A, Cline GW, Mandarino LJ, Shulman GI, DeFronzo RA. Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients. Diabetes 54: 3148-3153, 2005.
    • (2005) Diabetes , vol.54 , pp. 3148-3153
    • Bajaj, M.1    Suraamornkul, S.2    Romanelli, A.3    Cline, G.W.4    Mandarino, L.J.5    Shulman, G.I.6    DeFronzo, R.A.7
  • 9
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 54: 1615-1625, 2005.
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 11
    • 0026021161 scopus 로고
    • Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
    • DeFronzo RA, Ferrannini E. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14: 173-194, 1991.
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.A.1    Ferrannini, E.2
  • 12
    • 0021994683 scopus 로고
    • Effects of insulin on peripheral and splanchnic glucose metabolism in non-insulin-dependent (type II) diabetes mellitus
    • DeFronzo RA, Gunnarsson R, Bjorkman O, Olsson M, Wahren J. Effects of insulin on peripheral and splanchnic glucose metabolism in non-insulin-dependent (type II) diabetes mellitus. J Clin Invest 76: 149-155, 1985.
    • (1985) J Clin Invest , vol.76 , pp. 149-155
    • DeFronzo, R.A.1    Gunnarsson, R.2    Bjorkman, O.3    Olsson, M.4    Wahren, J.5
  • 14
    • 0024026298 scopus 로고
    • Lilly lecture 1987. The triumvirate: Beta-cell, muscle, liver. A collusion responsible for NIDDM
    • DeFronzo RA Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 37: 667-687, 1988.
    • (1988) Diabetes , vol.37 , pp. 667-687
    • DeFronzo, R.A.1
  • 15
    • 0035029812 scopus 로고    scopus 로고
    • Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes
    • Ducluzeau PH, Perretti N, Laville M, Andreelli F, Vega N, Riou JP, Vidal H. Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. Diabetes 50: 1134-1142, 2001.
    • (2001) Diabetes , vol.50 , pp. 1134-1142
    • Ducluzeau, P.H.1    Perretti, N.2    Laville, M.3    Andreelli, F.4    Vega, N.5    Riou, J.P.6    Vidal, H.7
  • 16
    • 0035016103 scopus 로고    scopus 로고
    • A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans
    • Duggirala R, Blangero J, Almasy L, Arya R, Dyer TD, Williams KL, Leach RJ, O'Connell P, Stern MP. A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans. Am J Hum Genet 68: 1149-1164, 2001.
    • (2001) Am J Hum Genet , vol.68 , pp. 1149-1164
    • Duggirala, R.1    Blangero, J.2    Almasy, L.3    Arya, R.4    Dyer, T.D.5    Williams, K.L.6    Leach, R.J.7    O'Connell, P.8    Stern, M.P.9
  • 20
    • 0036628008 scopus 로고    scopus 로고
    • Skeletal muscle triglyceride: Marker or mediator of obesity-induced insulin resistance in type 2 diabetes mellitus?
    • Goodpaster BH, Kelley DE. Skeletal muscle triglyceride: marker or mediator of obesity-induced insulin resistance in type 2 diabetes mellitus? Curr Diab Rep 2: 216-222, 2002.
    • (2002) Curr Diab Rep , vol.2 , pp. 216-222
    • Goodpaster, B.H.1    Kelley, D.E.2
  • 21
    • 4544364176 scopus 로고    scopus 로고
    • Expression profiling of insulin action in human myotubes: Induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes
    • Hansen L, Gaster M, Oakeley EJ, Brusgaard K, Damsgaard Nielsen EM, Beck-Nielsen H, Pedersen O, Hemmings BA. Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes. Biochem Biophys Res Commun 323: 685-695, 2004.
    • (2004) Biochem Biophys Res Commun , vol.323 , pp. 685-695
    • Hansen, L.1    Gaster, M.2    Oakeley, E.J.3    Brusgaard, K.4    Damsgaard Nielsen, E.M.5    Beck-Nielsen, H.6    Pedersen, O.7    Hemmings, B.A.8
  • 22
    • 0033536236 scopus 로고    scopus 로고
    • Insulin signaling in the arterial wall
    • Hsueh WA, Law RE. Insulin signaling in the arterial wall. Am J Cardiol 84: 21-24, 1999.
    • (1999) Am J Cardiol , vol.84 , pp. 21-24
    • Hsueh, W.A.1    Law, R.E.2
  • 24
    • 0035856598 scopus 로고    scopus 로고
    • Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms
    • Lang F, Cohen P. Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms. Sci STKE 108: RE17, 2001.
    • (2001) Sci STKE , vol.108
    • Lang, F.1    Cohen, P.2
  • 25
    • 0030037364 scopus 로고    scopus 로고
    • Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle
    • Laville M, Auboeuf D, Khalfallah Y, Vega N, Riou JP, Vidal H. Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle. J Clin Invest 98: 43-49, 1996.
    • (1996) J Clin Invest , vol.98 , pp. 43-49
    • Laville, M.1    Auboeuf, D.2    Khalfallah, Y.3    Vega, N.4    Riou, J.P.5    Vidal, H.6
  • 27
    • 0038054341 scopus 로고    scopus 로고
    • Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. PGC-1 a-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34: 267-273, 2003.
    • Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. PGC-1 a-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34: 267-273, 2003.
  • 28
    • 34249660144 scopus 로고    scopus 로고
    • Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Björnholm M, Tornqvist H, Zierath JR, Ridderstråle M, Altshuler D, Lee RT, Vaag A, Groop LC, Mootha VK. TXNIP regulates peripheral glucose metabolism in humans. PLoS Med 4: e158, 2007.
    • Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Björnholm M, Tornqvist H, Zierath JR, Ridderstråle M, Altshuler D, Lee RT, Vaag A, Groop LC, Mootha VK. TXNIP regulates peripheral glucose metabolism in humans. PLoS Med 4: e158, 2007.
  • 31
    • 0035937788 scopus 로고    scopus 로고
    • Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin
    • Perrotti N, He RA, Phillips SA, Haft CR, Taylor SI. Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin. J Biol Chem 276: 9406-9412, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 9406-9412
    • Perrotti, N.1    He, R.A.2    Phillips, S.A.3    Haft, C.R.4    Taylor, S.I.5
  • 32
    • 0023829632 scopus 로고
    • Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects
    • Polonsky KS, Given BD, Van Cauter E. Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. J Clin Invest 81: 442-448, 1988.
    • (1988) J Clin Invest , vol.81 , pp. 442-448
    • Polonsky, K.S.1    Given, B.D.2    Van Cauter, E.3
  • 34
    • 0029037649 scopus 로고
    • Pathophysiology of insulin resistance in human disease
    • Reaven GM. Pathophysiology of insulin resistance in human disease. Physiol Rev 75: 473-486, 1995.
    • (1995) Physiol Rev , vol.75 , pp. 473-486
    • Reaven, G.M.1
  • 35
    • 0027741390 scopus 로고
    • Rad: A member of the Ras family overexpressed in muscle of type II diabetic humans
    • Reynet C, Kahn CR. Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans. Science 262: 1441-1444, 1993.
    • (1993) Science , vol.262 , pp. 1441-1444
    • Reynet, C.1    Kahn, C.R.2
  • 36
    • 15444370639 scopus 로고    scopus 로고
    • Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle
    • Richardson DK, Kashyap S, Bajaj M, Cusi K, Mandarino SJ, Finlayson J, DeFronzo RA, Jenkinson CP, Mandarino LJ. Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle. J Biol Chem 280: 10290-10297, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 10290-10297
    • Richardson, D.K.1    Kashyap, S.2    Bajaj, M.3    Cusi, K.4    Mandarino, S.J.5    Finlayson, J.6    DeFronzo, R.A.7    Jenkinson, C.P.8    Mandarino, L.J.9
  • 37
    • 0038724906 scopus 로고    scopus 로고
    • Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp
    • Rome S, Clement K, Rabasa-Lhoret R, Loizon E, Poitou C, Barsh GS, Riou JP, Laville M, Vidal H. Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp. J Biol Chem 278: 18063-18068, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 18063-18068
    • Rome, S.1    Clement, K.2    Rabasa-Lhoret, R.3    Loizon, E.4    Poitou, C.5    Barsh, G.S.6    Riou, J.P.7    Laville, M.8    Vidal, H.9
  • 38
    • 33644674576 scopus 로고    scopus 로고
    • Metallothionein-mediated antioxidant defense system and its response to exercise training are impaired in human type 2 diabetes
    • Scheede-Bergdahl C, Penkowa M, Hidalgo J, Olsen DB, Schjerling P, Prats C, Boushel R, Dela F. Metallothionein-mediated antioxidant defense system and its response to exercise training are impaired in human type 2 diabetes. Diabetes 54: 3089-3094, 2005.
    • (2005) Diabetes , vol.54 , pp. 3089-3094
    • Scheede-Bergdahl, C.1    Penkowa, M.2    Hidalgo, J.3    Olsen, D.B.4    Schjerling, P.5    Prats, C.6    Boushel, R.7    Dela, F.8
  • 39
    • 0033595121 scopus 로고    scopus 로고
    • Glucose transporters and insulin action - implications for insulin resistance and diabetes mellitus
    • Shepherd PR, Kahn BB. Glucose transporters and insulin action - implications for insulin resistance and diabetes mellitus. N Engl J Med 341: 248-257, 1999.
    • (1999) N Engl J Med , vol.341 , pp. 248-257
    • Shepherd, P.R.1    Kahn, B.B.2
  • 40
    • 0036266251 scopus 로고    scopus 로고
    • Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment
    • Sreekumar R, Halvatsiotis P, Schimke JC, Nair KS. Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment. Diabetes 51: 1913-1920, 2002.
    • (2002) Diabetes , vol.51 , pp. 1913-1920
    • Sreekumar, R.1    Halvatsiotis, P.2    Schimke, J.C.3    Nair, K.S.4
  • 41
    • 2642518857 scopus 로고    scopus 로고
    • Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator
    • Tien ES, Davis JW, Vanden Heuvel JP. Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator. J Biol Chem 279: 24053-24063, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 24053-24063
    • Tien, E.S.1    Davis, J.W.2    Vanden Heuvel, J.P.3
  • 42
    • 0027325287 scopus 로고
    • Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus
    • Vestergaard H, Lund S, Larsen FS, Bjerrum OJ, Pedersen O. Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus. J Clin Invest 91: 2342-2350, 1993.
    • (1993) J Clin Invest , vol.91 , pp. 2342-2350
    • Vestergaard, H.1    Lund, S.2    Larsen, F.S.3    Bjerrum, O.J.4    Pedersen, O.5
  • 44
    • 0036435899 scopus 로고    scopus 로고
    • Microarray profiling of skeletal muscle tissues from equally obese, non-diabetic insulin-sensitive and insulin-resistant Pima Indians
    • Yang X, Pratley RE, Tokraks S, Bogardus C, Permana PA. Microarray profiling of skeletal muscle tissues from equally obese, non-diabetic insulin-sensitive and insulin-resistant Pima Indians. Diabetologia 45: 1584-1593, 2002.
    • (2002) Diabetologia , vol.45 , pp. 1584-1593
    • Yang, X.1    Pratley, R.E.2    Tokraks, S.3    Bogardus, C.4    Permana, P.A.5


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