-
1
-
-
0022590628
-
Defense strategies against hypoxia and hypothermia
-
Hochachka,P.W. (1986) Defense strategies against hypoxia and hypothermia. Science, 231, 234-241.
-
(1986)
Science
, vol.231
, pp. 234-241
-
-
Hochachka, P.W.1
-
2
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim,J.W., Tchernyshyov,I., Semenza,G.L. and Dang,C.V. (2006) HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia. Cell Metab., 3, 177-185.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
3
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
-
Zhang,H., Gao,P., Fukuda,R., Kumar,G., Krishnamachary,B., Zeller,K.I., Dang,C.V. and Semenza,G.L. (2007) HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell, 11, 407-420.
-
(2007)
Cancer Cell
, vol.11
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
Kumar, G.4
Krishnamachary, B.5
Zeller, K.I.6
Dang, C.V.7
Semenza, G.L.8
-
4
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
Papandreou,I., Cairns,R.A., Fontana,L., Lim,A.L. and Denko,N.C. (2006) HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab., 3, 187-197.
-
(2006)
Cell Metab
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
5
-
-
0035917808
-
-
2-regulated prolyl hydroxylation. Science 292, 468-472.
-
2-regulated prolyl hydroxylation. Science 292, 468-472.
-
-
-
-
7
-
-
0037315337
-
Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs
-
Wiesener,M.S., Jurgensen,J.S., Rosenberger,C., Scholze,C.K., Horstrup,J.H., Warnecke,C., Mandriota,S., Bechmann,I., Frei,U.A., Pugh,C.W. et al. (2003) Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. FASEB J. 17, 271-273.
-
(2003)
FASEB J
, vol.17
, pp. 271-273
-
-
Wiesener, M.S.1
Jurgensen, J.S.2
Rosenberger, C.3
Scholze, C.K.4
Horstrup, J.H.5
Warnecke, C.6
Mandriota, S.7
Bechmann, I.8
Frei, U.A.9
Pugh, C.W.10
-
8
-
-
34247477207
-
Hypoxia inducible factor-2alpha in cancer
-
Löfstedt,T., Fredlund,E., Holmquist-Mengelbier,L., Pietras,A., Ovenberger,M., Poellinger,L. and Påhlman,S. (2007) Hypoxia inducible factor-2alpha in cancer. Cell Cycle, 6, 919-926.
-
(2007)
Cell Cycle
, vol.6
, pp. 919-926
-
-
Löfstedt, T.1
Fredlund, E.2
Holmquist-Mengelbier, L.3
Pietras, A.4
Ovenberger, M.5
Poellinger, L.6
Påhlman, S.7
-
9
-
-
0029796904
-
Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack
-
Hochachka,P.W., Buck,L.T., Doll,C.J. and Land,S.C. (1996) Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc. Natl Acad. Sci. USA, 93, 9493-9498.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 9493-9498
-
-
Hochachka, P.W.1
Buck, L.T.2
Doll, C.J.3
Land, S.C.4
-
10
-
-
0035038782
-
Mechanisms of nutritional and hormonal regulation of lipogenesis
-
Kersten,S. (2001) Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Rep., 2, 282-286.
-
(2001)
EMBO Rep
, vol.2
, pp. 282-286
-
-
Kersten, S.1
-
11
-
-
2442490613
-
The human fatty acid synthase gene and de novo lipogenesis are coordinately regulated in human adipose tissue
-
Wang,Y., Jones Voy,B., Urs,S., Kim,S., Soltani-Bejnood,M., Quigley,N., Heo,Y.R., Standridge,M., Andersen,B., Dhar,M. et al. (2004) The human fatty acid synthase gene and de novo lipogenesis are coordinately regulated in human adipose tissue. J. Nutr., 134, 1032-1038.
-
(2004)
J. Nutr
, vol.134
, pp. 1032-1038
-
-
Wang, Y.1
Jones Voy, B.2
Urs, S.3
Kim, S.4
Soltani-Bejnood, M.5
Quigley, N.6
Heo, Y.R.7
Standridge, M.8
Andersen, B.9
Dhar, M.10
-
12
-
-
0028875426
-
Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways
-
Bennett,M.K., Lopez,J.M., Sanchez,H.B. and Osborne,T.F. (1995) Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways. J. Biol. Chem., 270, 25578-25583.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 25578-25583
-
-
Bennett, M.K.1
Lopez, J.M.2
Sanchez, H.B.3
Osborne, T.F.4
-
13
-
-
0028897395
-
In vivo effects of hyperinsulinemia on lipogenic enzymes and glucose transporter expression in rat liver and adipose tissues
-
Assimacopoulos-Jeannet,F., Brichard,S., Rencurel,F., Cusin,I. and Jeanrenaud,B. (1995) In vivo effects of hyperinsulinemia on lipogenic enzymes and glucose transporter expression in rat liver and adipose tissues. Metabolism, 44, 228-233.
-
(1995)
Metabolism
, vol.44
, pp. 228-233
-
-
Assimacopoulos-Jeannet, F.1
Brichard, S.2
Rencurel, F.3
Cusin, I.4
Jeanrenaud, B.5
-
14
-
-
0028963743
-
Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain
-
Kim,J.B., Spotts,G.D., Halvorsen,Y.D., Shih,H.M., Ellenberger,T., Towle,H.C. and Spiegelman,B.M. (1995) Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Mol. Cell. Biol., 15, 2582-2588.
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 2582-2588
-
-
Kim, J.B.1
Spotts, G.D.2
Halvorsen, Y.D.3
Shih, H.M.4
Ellenberger, T.5
Towle, H.C.6
Spiegelman, B.M.7
-
15
-
-
0030961960
-
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
-
Shimomura,I., Shimano,H., Horton,J.D., Goldstein,J.L. and Brown,M.S. (1997) Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J. Clin. Invest., 99, 838-845.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 838-845
-
-
Shimomura, I.1
Shimano, H.2
Horton, J.D.3
Goldstein, J.L.4
Brown, M.S.5
-
16
-
-
0034613175
-
Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene
-
Amemiya-Kudo,M., Shimano,H., Yoshikawa,T., Yahagi,N., Hasty,A.H., Okazaki,H., Tamura,Y., Shionoiri,F., Iizuka,Y., Ohashi,K. et al. (2000) Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene. J. Biol. Chem., 275, 31078-31085.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 31078-31085
-
-
Amemiya-Kudo, M.1
Shimano, H.2
Yoshikawa, T.3
Yahagi, N.4
Hasty, A.H.5
Okazaki, H.6
Tamura, Y.7
Shionoiri, F.8
Iizuka, Y.9
Ohashi, K.10
-
17
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
-
Repa,J.J., Liang,G., Ou,J., Bashmakov,Y., Lobaccaro,J.M., Shimomura,I., Shan,B., Brown,M.S., Goldstein,J.L. and Mangelsdorf,D.J. (2000) Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev. 14, 2819-2830.
-
(2000)
Genes Dev
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.M.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
18
-
-
19344361859
-
Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues
-
Gosmain,Y., Dif,N., Berbe,V., Loizon,E., Rieusset,J., Vidal,H. and Lefai,E. (2005) Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues. J. Lipid. Res., 46, 697-705.
-
(2005)
J. Lipid. Res
, vol.46
, pp. 697-705
-
-
Gosmain, Y.1
Dif, N.2
Berbe, V.3
Loizon, E.4
Rieusset, J.5
Vidal, H.6
Lefai, E.7
-
19
-
-
3843061127
-
Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver
-
Chen,G., Liang,G., Ou,J., Goldstein,J.L. and Brown,M.S. (2004) Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc. Natl Acad. Sci. USA, 101, 11245-11250.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 11245-11250
-
-
Chen, G.1
Liang, G.2
Ou, J.3
Goldstein, J.L.4
Brown, M.S.5
-
20
-
-
0036198010
-
Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: A mechanism for regulation of adipogenesis by hypoxia
-
Yun,Z., Maecker,H.L., Johnson,R.S. and Giaccia,A.J. (2002) Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: A mechanism for regulation of adipogenesis by hypoxia. Dev. Cell, 2, 331-341.
-
(2002)
Dev. Cell
, vol.2
, pp. 331-341
-
-
Yun, Z.1
Maecker, H.L.2
Johnson, R.S.3
Giaccia, A.J.4
-
21
-
-
0037033095
-
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes
-
Miyazaki,K., Kawamoto,T., Tanimoto,K., Nishiyama,M., Honda,H. and Kato,Y. (2002) Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J. Biol. Chem., 277, 47014-47021.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 47014-47021
-
-
Miyazaki, K.1
Kawamoto, T.2
Tanimoto, K.3
Nishiyama, M.4
Honda, H.5
Kato, Y.6
-
22
-
-
21344471947
-
Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their gene expressions are regulated by multiple extracellular stimuli
-
Yamada,K. and Miyamoto,K. (2005) Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their gene expressions are regulated by multiple extracellular stimuli. Front Biosci., 10, 3151-3171.
-
(2005)
Front Biosci
, vol.10
, pp. 3151-3171
-
-
Yamada, K.1
Miyamoto, K.2
-
23
-
-
10744220537
-
Twist2, a novel ADD1/SREBP1c interacting protein, represses the transcriptional activity of ADD1/SREBP1c
-
Lee,Y.S., Lee,H.H., Park,J., Yoo,E.J., Glackin,C.A., Choi,Y.I., Jeon,S.H., Seong,R.H., Park,S.D. and Kim,J.B. (2003) Twist2, a novel ADD1/SREBP1c interacting protein, represses the transcriptional activity of ADD1/SREBP1c. Nucleic Acids Res., 31, 7165-7174.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 7165-7174
-
-
Lee, Y.S.1
Lee, H.H.2
Park, J.3
Yoo, E.J.4
Glackin, C.A.5
Choi, Y.I.6
Jeon, S.H.7
Seong, R.H.8
Park, S.D.9
Kim, J.B.10
-
24
-
-
0031963963
-
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1
-
Kim,J.B., Sarraf,P., Wright,M., Yao,K.M., Mueller,E., Solanes,G., Lowell,B.B. and Spiegelman,B.M. (1998) Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J. Clin. Invest., 101, 1-9.
-
(1998)
J. Clin. Invest
, vol.101
, pp. 1-9
-
-
Kim, J.B.1
Sarraf, P.2
Wright, M.3
Yao, K.M.4
Mueller, E.5
Solanes, G.6
Lowell, B.B.7
Spiegelman, B.M.8
-
25
-
-
33845922640
-
Clioquinol, a Cu(II)/Zn(II) chelator, inhibits both ubiquitination and asparagine hydroxylation of hypoxia-inducible factor-1alpha, leading to expression of vascular endothelial growth factor and erythropoietin in normoxic cells
-
Choi,S.M., Choi,K.O., Park,Y.K., Cho,H., Yang,E.G. and Park,H. (2006) Clioquinol, a Cu(II)/Zn(II) chelator, inhibits both ubiquitination and asparagine hydroxylation of hypoxia-inducible factor-1alpha, leading to expression of vascular endothelial growth factor and erythropoietin in normoxic cells. J. Biol. Chem., 281, 34056-34063.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 34056-34063
-
-
Choi, S.M.1
Choi, K.O.2
Park, Y.K.3
Cho, H.4
Yang, E.G.5
Park, H.6
-
26
-
-
0141643339
-
Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha
-
Yim,S., Choi,S.M., Choi,Y., Lee,N., Chung,J. and Park,H. (2003) Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha. J. Biol. Chem., 278, 38260-38268.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 38260-38268
-
-
Yim, S.1
Choi, S.M.2
Choi, Y.3
Lee, N.4
Chung, J.5
Park, H.6
-
27
-
-
40649089223
-
Analysis of epigenetic modifications of chromatin at specific gene loci by native chromatin immunoprecipitation of nucleosomes isolated using hydroxyapatite chromatography
-
Brand,M., Rampalli,S., Chaturvedi,C.P. and Dilworth,F.J. (2008) Analysis of epigenetic modifications of chromatin at specific gene loci by native chromatin immunoprecipitation of nucleosomes isolated using hydroxyapatite chromatography. Nat. Protoc., 3, 398-409.
-
(2008)
Nat. Protoc
, vol.3
, pp. 398-409
-
-
Brand, M.1
Rampalli, S.2
Chaturvedi, C.P.3
Dilworth, F.J.4
-
28
-
-
0020680990
-
A peroxidase-coupled method for the colorimetric determination of serum triglycerides
-
McGowan,M.W., Artiss,J.D., Strandbergh,D.R. and Zak,B. (1983) A peroxidase-coupled method for the colorimetric determination of serum triglycerides. Clin. Chem., 29, 538-542.
-
(1983)
Clin. Chem
, vol.29
, pp. 538-542
-
-
McGowan, M.W.1
Artiss, J.D.2
Strandbergh, D.R.3
Zak, B.4
-
29
-
-
0031015287
-
Exogenous oxidized low-density lipoprotein injures and alters the barrier function of endothelium in rats in vivo
-
Rangaswamy,S., Penn,M.S., Saidel,G.M. and Chisolm,G.M. (1997) Exogenous oxidized low-density lipoprotein injures and alters the barrier function of endothelium in rats in vivo. Circ. Res., 80, 37-44.
-
(1997)
Circ. Res
, vol.80
, pp. 37-44
-
-
Rangaswamy, S.1
Penn, M.S.2
Saidel, G.M.3
Chisolm, G.M.4
-
30
-
-
11144356074
-
Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression
-
Seo,J.B., Moon,H.M., Kim,W.S., Lee,Y.S., Jeong,H.W., Yoo,E.J., Ham,J., Kang,H., Park,M.G., Steffensen,K.R. et al. (2004) Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression. Mol. Cell. Biol., 24, 3430-3444.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 3430-3444
-
-
Seo, J.B.1
Moon, H.M.2
Kim, W.S.3
Lee, Y.S.4
Jeong, H.W.5
Yoo, E.J.6
Ham, J.7
Kang, H.8
Park, M.G.9
Steffensen, K.R.10
-
31
-
-
34247359442
-
Chronic intermittent hypoxia predisposes to liver injury
-
Savransky,V., Nanayakkara,A., Vinero,A., Li,J., Bevans,S., Smith,P.L., Torbenson,M.S. and Polotsky,V.Y. (2007) Chronic intermittent hypoxia predisposes to liver injury. Hepatology, 45, 1007-1013.
-
(2007)
Hepatology
, vol.45
, pp. 1007-1013
-
-
Savransky, V.1
Nanayakkara, A.2
Vinero, A.3
Li, J.4
Bevans, S.5
Smith, P.L.6
Torbenson, M.S.7
Polotsky, V.Y.8
-
32
-
-
56649099909
-
Aryl hydrocarbon receptor nuclear translocator is involved in ATP homeostasis in both normoxic and hypoxic monolayer mouse hepatoma cells
-
Choi,S.M. and Park,H. (2006) Aryl hydrocarbon receptor nuclear translocator is involved in ATP homeostasis in both normoxic and hypoxic monolayer mouse hepatoma cells. J. Appl. Pharmacol., 14, 132-136.
-
(2006)
J. Appl. Pharmacol
, vol.14
, pp. 132-136
-
-
Choi, S.M.1
Park, H.2
-
33
-
-
0035027828
-
Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells
-
Seagroves,T.N., Ryan,H.E., Lu,H., Wouters,B.G., Knapp,M., Thibault,P., Laderoute,K. and Johnson,R.S. (2001) Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. Mol. Cell. Biol., 21, 3436-3444.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 3436-3444
-
-
Seagroves, T.N.1
Ryan, H.E.2
Lu, H.3
Wouters, B.G.4
Knapp, M.5
Thibault, P.6
Laderoute, K.7
Johnson, R.S.8
-
34
-
-
0029655655
-
Dioxin-induced CYP1A1 transcription in vivo: The aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure
-
Ko,H.P., Okino,S.T., Ma,Q. and Whitlock,J.P. Jr. (1996) Dioxin-induced CYP1A1 transcription in vivo: The aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure. Mol. Cell. Biol., 16, 430-436.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 430-436
-
-
Ko, H.P.1
Okino, S.T.2
Ma, Q.3
Whitlock Jr., J.P.4
-
35
-
-
33750630119
-
Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype
-
Holmquist-Mengelbier,L., Fredlund,E., Löfstedt,T., Noguera,R., Navarro,S., Nilsson,H., Pietras,A., Vallon-Christersson,J., Borg,A., Gradin,K. et al. (2006) Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell, 10 413-423.
-
(2006)
Cancer Cell
, vol.10
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Löfstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
Pietras, A.7
Vallon-Christersson, J.8
Borg, A.9
Gradin, K.10
-
36
-
-
12744271884
-
Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements
-
Cagen,L.M., Deng,X., Wilcox,H.G., Park,E.A., Raghow,R. and Elam,M.B. (2005) Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements. Biochem. J., 385 207-216.
-
(2005)
Biochem. J
, vol.385
, pp. 207-216
-
-
Cagen, L.M.1
Deng, X.2
Wilcox, H.G.3
Park, E.A.4
Raghow, R.5
Elam, M.B.6
-
37
-
-
0037930808
-
DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter
-
Li,Y., Xie,M., Song,X., Gragen,S., Sachdeva,K., Wan,Y. and Yan,B. (2003) DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter. J. Biol. Chem., 278, 16899-16907.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 16899-16907
-
-
Li, Y.1
Xie, M.2
Song, X.3
Gragen, S.4
Sachdeva, K.5
Wan, Y.6
Yan, B.7
-
38
-
-
10744225254
-
A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation
-
Kawamoto,T., Noshiro,M., Sato,F., Maemura,K., Takeda,N., Nagai,R., Iwata,T., Fujimoto,K., Furukawa,M., Miyazaki,K. et al. (2004) A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation. Biochem. Biophys. Res. Commun., 313, 117-124.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.313
, pp. 117-124
-
-
Kawamoto, T.1
Noshiro, M.2
Sato, F.3
Maemura, K.4
Takeda, N.5
Nagai, R.6
Iwata, T.7
Fujimoto, K.8
Furukawa, M.9
Miyazaki, K.10
-
39
-
-
12644314084
-
Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter
-
Magana,M.M. and Osborne,T.F. (1996) Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter. J. Biol. Chem., 271, 32689-32694.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 32689-32694
-
-
Magana, M.M.1
Osborne, T.F.2
-
40
-
-
0030868519
-
Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins
-
Magana,M.M., Lin,S.S., Dooley,K.A. and Osborne,T.F. (1997) Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins. J. Lipid Res., 38, 1630-1638.
-
(1997)
J. Lipid Res
, vol.38
, pp. 1630-1638
-
-
Magana, M.M.1
Lin, S.S.2
Dooley, K.A.3
Osborne, T.F.4
-
41
-
-
47049105096
-
Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2
-
Nakamura,H., Tanimoto,K., Hiyama,K., Yunokawa,M., Kawamoto,T., Kato,Y., Yoshiga,K., Poellinger,L., Hiyama,E. and Nishiyama,M. (2008) Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2. Oncogene, 27, 4200-4209.
-
(2008)
Oncogene
, vol.27
, pp. 4200-4209
-
-
Nakamura, H.1
Tanimoto, K.2
Hiyama, K.3
Yunokawa, M.4
Kawamoto, T.5
Kato, Y.6
Yoshiga, K.7
Poellinger, L.8
Hiyama, E.9
Nishiyama, M.10
-
42
-
-
34447556690
-
Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis
-
Noshiro,M., Usui,E., Kawamoto,T., Kubo,H., Fujimoto,K., Furukawa,M., Honma,S., Makishima,M., Honma,K. and Kato,Y. (2007) Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis. J. Biol. Rhythms, 22, 299-311.
-
(2007)
J. Biol. Rhythms
, vol.22
, pp. 299-311
-
-
Noshiro, M.1
Usui, E.2
Kawamoto, T.3
Kubo, H.4
Fujimoto, K.5
Furukawa, M.6
Honma, S.7
Makishima, M.8
Honma, K.9
Kato, Y.10
-
43
-
-
0037167847
-
Dec1 and Dec2 are regulators of the mammalian molecular clock
-
Honma,S., Kawamoto,T., Takagi,Y., Fujimoto,K., Sato,F., Noshiro,M., Kato,Y. and Honma,K. (2002) Dec1 and Dec2 are regulators of the mammalian molecular clock. Nature, 419, 841-844.
-
(2002)
Nature
, vol.419
, pp. 841-844
-
-
Honma, S.1
Kawamoto, T.2
Takagi, Y.3
Fujimoto, K.4
Sato, F.5
Noshiro, M.6
Kato, Y.7
Honma, K.8
-
44
-
-
4744373356
-
DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1
-
Li,Y., Song,X., Ma,Y., Liu,J., Yang,D. and Yan,B. (2004) DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1. Biochem. J., 382, 895-904.
-
(2004)
Biochem. J
, vol.382
, pp. 895-904
-
-
Li, Y.1
Song, X.2
Ma, Y.3
Liu, J.4
Yang, D.5
Yan, B.6
-
45
-
-
33747157406
-
Nuclear receptor expression links the circadian clock to metabolism
-
Yang,X., Downes,M., Yu,R.T., Bookout,A.L., He,W., Straume,M., Mangelsdorf,D.J. and Evans,R.M. (2006) Nuclear receptor expression links the circadian clock to metabolism. Cell, 126, 801-810.
-
(2006)
Cell
, vol.126
, pp. 801-810
-
-
Yang, X.1
Downes, M.2
Yu, R.T.3
Bookout, A.L.4
He, W.5
Straume, M.6
Mangelsdorf, D.J.7
Evans, R.M.8
-
46
-
-
33645790960
-
Characterization of peripheral circadian clocks in adipose tissues
-
Zvonic,S., Ptitsyn,A.A., Conrad,S.A., Scott,L.K., Floyd,Z.E., Kilroy,G., Wu,X., Goh,B.C., Mynatt,R.L. and Gimble,J.M. (2006) Characterization of peripheral circadian clocks in adipose tissues. Diabetes, 55 962-970.
-
(2006)
Diabetes
, vol.55
, pp. 962-970
-
-
Zvonic, S.1
Ptitsyn, A.A.2
Conrad, S.A.3
Scott, L.K.4
Floyd, Z.E.5
Kilroy, G.6
Wu, X.7
Goh, B.C.8
Mynatt, R.L.9
Gimble, J.M.10
-
47
-
-
24944497666
-
Tissue-specific disruption of rhythmic expression of Dec1 and Dec2 in clock mutant mice
-
Noshiro,M., Furukawa,M., Honma,S., Kawamoto,T., Hamada,T., Honma,K. and Kato,Y. (2005) Tissue-specific disruption of rhythmic expression of Dec1 and Dec2 in clock mutant mice. J. Biol. Rhythms, 20, 404-418.
-
(2005)
J. Biol. Rhythms
, vol.20
, pp. 404-418
-
-
Noshiro, M.1
Furukawa, M.2
Honma, S.3
Kawamoto, T.4
Hamada, T.5
Honma, K.6
Kato, Y.7
-
48
-
-
0035065450
-
Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-de.cient mice
-
Patel,D.D., Knight,B.L., Wiggins,D., Humphreys,S.M. and Gibbons,G.F. (2001) Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-de.cient mice. J. Lipid Res., 42, 328-337.
-
(2001)
J. Lipid Res
, vol.42
, pp. 328-337
-
-
Patel, D.D.1
Knight, B.L.2
Wiggins, D.3
Humphreys, S.M.4
Gibbons, G.F.5
-
49
-
-
0033572654
-
Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adipocytes
-
Moldes,M., Boizard,M., Liepvre,X.L., Feve,B., Dugail,I. and Pairault,J. (1999) Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adipocytes. Biochem. J. 344, 873-880.
-
(1999)
Biochem. J
, vol.344
, pp. 873-880
-
-
Moldes, M.1
Boizard, M.2
Liepvre, X.L.3
Feve, B.4
Dugail, I.5
Pairault, J.6
-
50
-
-
34247119238
-
Direct interaction between USF and SREBP-1c mediates synergistic activation of the fatty acid synthase promoter
-
Griffin,M.J., Wong,R.H., Pandya,N. and Sul,H.S. (2006) Direct interaction between USF and SREBP-1c mediates synergistic activation of the fatty acid synthase promoter. J. Biol. Chem., 282, 5453-5467.
-
(2006)
J. Biol. Chem
, vol.282
, pp. 5453-5467
-
-
Griffin, M.J.1
Wong, R.H.2
Pandya, N.3
Sul, H.S.4
-
51
-
-
0035797525
-
Cross-regulatory interaction between Stra13 and USF results in functional antagonism
-
Dhar,M. and Taneja,R. (2001) Cross-regulatory interaction between Stra13 and USF results in functional antagonism. Oncogene, 20, 4750-4756.
-
(2001)
Oncogene
, vol.20
, pp. 4750-4756
-
-
Dhar, M.1
Taneja, R.2
-
52
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cnacer pathogenesis
-
Menendez,J.A. and Lupu,R. (2007) Fatty acid synthase and the lipogenic phenotype in cnacer pathogenesis. Nat. Rev. Cancer, 7, 763-777.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
53
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
-
DeBerardinis,R.J., Lum,J.J., Hatzivassiliou,G. and Thompson,C.B. (2008) The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation. Cell Metab., 7, 11-20.
-
(2008)
Cell Metab
, vol.7
, pp. 11-20
-
-
DeBerardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
54
-
-
0034724397
-
Synthesis and antitumor activity of an inhibitor of fatty acid synthase
-
Kuhajda,F.P., Pizer,E.S., Li,J.N., Mani,N.S., Frehywot,G.L. and Townsend,C.A. (2000) Synthesis and antitumor activity of an inhibitor of fatty acid synthase. Proc. Natl Acad. Sci. USA, 97, 3450-3454.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3450-3454
-
-
Kuhajda, F.P.1
Pizer, E.S.2
Li, J.N.3
Mani, N.S.4
Frehywot, G.L.5
Townsend, C.A.6
-
55
-
-
6344227760
-
Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand
-
Bauer,D.E., Harris,M.H., Plas,D.R., Lum,J.J., Hammerman,P.S., Rathmell,J.C., Riley,J.L. and Thompson,C.B. (2004) Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. FASEB J., 18, 1303-1305.
-
(2004)
FASEB J
, vol.18
, pp. 1303-1305
-
-
Bauer, D.E.1
Harris, M.H.2
Plas, D.R.3
Lum, J.J.4
Hammerman, P.S.5
Rathmell, J.C.6
Riley, J.L.7
Thompson, C.B.8
-
56
-
-
34247631690
-
The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
-
Lum,J.J., Bui,T., Gruber,M., Gordan,J.D., DeBerardinis,R.J., Covello,K.L., Simon,M.C. and Thompson,C.B. (2007) The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes Dev., 21, 1037-1049.
-
(2007)
Genes Dev
, vol.21
, pp. 1037-1049
-
-
Lum, J.J.1
Bui, T.2
Gruber, M.3
Gordan, J.D.4
DeBerardinis, R.J.5
Covello, K.L.6
Simon, M.C.7
Thompson, C.B.8
-
57
-
-
0037177867
-
Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1α nor sufficient for HIF-1-dependent target gene transcription
-
Arsham,A.M., Plas,D.R., Thompson,C.B. and Simon,M.C. (2002) Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1α nor sufficient for HIF-1-dependent target gene transcription. J. Biol. Chem., 277, 15162-15170.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 15162-15170
-
-
Arsham, A.M.1
Plas, D.R.2
Thompson, C.B.3
Simon, M.C.4
-
58
-
-
39549117982
-
Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1
-
Furuta,E., Pai,S.K., Zhan,R., Bandyopadhyay,S., Watabe,M., Mo,Y.Y., Hirota,S., Hosobe,S., Tsukada,T., Miura,K. et al. (2008) Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1. Cancer Res., 68 1003-1011.
-
(2008)
Cancer Res
, vol.68
, pp. 1003-1011
-
-
Furuta, E.1
Pai, S.K.2
Zhan, R.3
Bandyopadhyay, S.4
Watabe, M.5
Mo, Y.Y.6
Hirota, S.7
Hosobe, S.8
Tsukada, T.9
Miura, K.10
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