Click chemistry based rapid one-pot synthesis and evaluation for protease inhibition of new tetracyclic triazole fused benzodiazepine derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 17, 2009, Pages 5241-5245

  Mohapatra, Debendra K ^a,b   Maity, Pradip K ^a   Shabab, M ^a   Khan, M I ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,11A TETRAHYDRO 8 HYDROXY 7 METHOXY 5H PYRROLO[2,1 C][1,4]BENZODIAZEPIN 5 ONE; 5 (BENZYLOXY)BENZO[E]PYRROLO[1,2 A][1,2,3] TRIAZOLO[5,1 C][1,4]DIAZEPIN 8(4H) ONE; 5 (BENZYLOXY)BENZO[E]PYRROLO[1,2 A][1,2,3]TRIAZOLO[5,1 C][1,4]DIAZEPIN 8(4H) ONE; ABBEYMYCIN; ANTHRAMYCIN; BENZO[E]PYRROLO[1,2 A][1,2,3]TRIAZOLO[5,1 C][1,4]DIAZEPIN 8(4H) ONE; BENZODIAZEPINE DERIVATIVE; BRETAZENIL; NEOTHRAMYCIN; PROTEINASE INHIBITOR; PYRROLO[2,1 C][1,4] BENZODIAZEPIN 5 ONE; PYRROLO[2,1 C][1,4]BENZODIAZEPINE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CRYSTAL STRUCTURE; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; PROTEINASE INHIBITION; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY DIFFRACTION;

BENZODIAZEPINES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; MOLECULAR CONFORMATION; PROTEASE INHIBITORS; SERINE ENDOPEPTIDASES; TRIAZOLES;

EID: 68349130204     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.06.107     Document Type: Article

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