Convergent approach toward the synthesis of the stereoisomers of C-6 homologues of 1-deoxynojirimycin and their analogues: Evaluation as specific glycosidase inhibitors

Journal of Organic Chemistry

Volumn 71, Issue 22, 2006, Pages 8481-8488

  Pandey, Ganesh ^a   Dumbre, Shrinivas G ^a   Khan, M Islam ^a   Shabab, M ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ENANTIOMERS; GLYCOSIDASE INHIBITORS; STEREOISOMERS; STEREOSELECTIVITY;

ISOMERS;

1 DEOXY 4 HYDROXYMETHYL DEXTRO GLUCOHOMONOJIRIMYCIN; 1 DEOXY DEXTRO GALACTOHOMONOJIRIMYCIN; 1 DEOXYNOJIRIMYCIN; 2 (2 HYDROXYETHYL)PIPERIDINE 3,4,5 TRIOL; 2,2 DIMETHYL 10 METHYLENEHEXAHYDRO 4H 1,3 DIOXOLO[4,5]PYRIDO[1,2C][1,3]OXAZINE; ALPHA GALACTOSIDASE; BETA GLUCOSIDASE; CARBOHYDRATE DERIVATIVE; CARBON; GALACTOSE; GLUCOSE DERIVATIVE; GLYCOSIDASE INHIBITOR; LACTAM DERIVATIVE; METHYL GROUP; OXAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BINDING; CHEMICAL STRUCTURE; ENANTIOMER; ENANTIOSELECTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; STEREOCHEMISTRY; STEREOISOMERISM; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS; SYNTHESIS;

1-DEOXYNOJIRIMYCIN; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GLYCOSIDE HYDROLASES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33750487513     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo061455v     Document Type: Article

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