Immune response induced by fluorescent nanocrystal quantum dots in vitro and in vivo

IEEE Transactions on Nanobioscience

Volumn 8, Issue 1, 2009, Pages 51-57

  Hoshino, Akiyoshi ^a   Hanada, Sanshiro ^a,b   Manabe, Noriyoshi ^a,b   Nakayama, Toshinori ^c   Yamamoto, Kenji ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b Japan Association for the Advancement of Medical Equipment   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

+ T lymphocyte; Cytotoxicity; Immune response; Inflammation; Lymphocyte; Macrophage; Nanocrystal; Nanoscale products; Peritoneal macrophage (PM ); Quantum dots (QDs); Toxicity

Indexed keywords

+ T LYMPHOCYTE; IMMUNE RESPONSE; INFLAMMATION; LYMPHOCYTE; NANOSCALE PRODUCTS; QUANTUM DOTS (QDS);

BIOCHEMISTRY; CELL CULTURE; CELL MEMBRANES; CYTOTOXICITY; FLUORESCENCE; MACROPHAGES; MAMMALS; MOLECULAR BIOLOGY; NANOCRYSTALS; NANOSTRUCTURED MATERIALS; NUCLEIC ACIDS; NUCLEOTIDES; PATHOLOGY; PEPTIDES; PERMANENT MAGNETS;

SEMICONDUCTOR QUANTUM DOTS;

CHEMOKINE; CYTOKINE; ENHANCED GREEN FLUORESCENT PROTEIN; NANOCRYSTAL; NANOPARTICLE; NUCLEOTIDE; QUANTUM DOT;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CD4+ T LYMPHOCYTE; CELL LABELING; CONTROLLED STUDY; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE CULTURE; MACROPHAGE; MALE; MOUSE; NANOTECHNOLOGY; NONHUMAN; PERITONEAL CAVITY; PROTEIN EXPRESSION;

ANIMALS; CELLS, CULTURED; IMMUNITY, INNATE; INFLAMMATION; MACROPHAGES; MATERIALS TESTING; MICE; MICE, INBRED BALB C; QUANTUM DOTS;

MAMMALIA; MUS;

EID: 68149176628     PISSN: 15361241     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNB.2009.2016550     Document Type: Article

References (68)

1. R. Kubo, "Statistical-mechanical theory of irreversible processes," J. Phys. Soc. Jpn., vol. 12, pp. 570-586, 1957.
2. R. Kubo, "Generalized cumulant expansion method," J. Phys. Soc. Jpn., vol. 17, pp. 1100-1120, 1962.
3. R. Kubo, "Stochastic liouville equations," J. Math. Phys., vol. 4, pp. 174-183, 1962.
4. M. A. Hines and P. Guyot-Sionnest, "Synthesis and characterization of strongly luminescing ZnS-capped CdSe nanocrystals," J. Phys. Chem., vol. 100, pp. 468-471, 1996.
5. B. O. Dabbousi, J. Rodriguez-Viejo, F. V. Mikulec, J. R. Heine, H. Mattoussi, R. Ober, K. F. Jensen, and M. Bawendi, "(CdSe)ZnS core-shell quantum dots: Synthesis and characterization of a size series of highly luminescent nanocrystallites," J. Phys. Chem., vol. 101, pp. 9463-9475, 1997.
6. W. C. Chan, D. J. Maxwell, X. Gao, R. E. Bailey, M. Han, and S. Nie, "Luminescent quantum dots for multiplexed biological detection and imaging," Curr. Opin. Biotechnol., vol. 13, pp. 40-46, 2002.
7. W. C. Chan and S. Nie, "Quantum dot bioconjugates for ultrasensitive nonisotopic detection," Science, vol. 281, pp. 2016-2018, 1998.
8. J. K. Jaiswal, H. Mattoussi, J. M. Mauro, and S. M. Simon, "Long-term multiple color imaging of live cells using quantum dot bioconjugates," Nat. Biotechnol., vol. 21, pp. 47-51, 2003.
9. M. Osinski, T. M. Jovin, and K. Yamamoto, "Biomedical applications of colloidal nanocrystals," J. Biomed. Biotechnol., vol. 2007, pp. 82752-1-82752-3, 2007.
10. A. P. Alivisatos, W. Gu, and C. Larabell, "Quantum dots as cellular probes," Annu. Rev. Biomed. Eng., vol. 7, pp. 55-76, 2005.
11. C. Z. Hotz, "Applications of quantum dots in biology: An overview," Methods Mol. Biol., vol. 303, pp. 1-17, 2005.
12. X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, "Quantum dots for live cells, in vivo imaging, and diagnostics," Science, vol. 307, pp. 538-544, 2005.
13. S. M. Rozenzhak, M. P. Kadakia, T. M. Caserta, T. R. Westbrook, M. O. Stone, and R. R. Naik, "Cellular internalization and targeting of semiconductor quantum dots," Chem. Commun. (Camb.), vol. 7, no. 17, pp. 2217-2219, 2005.
14. H. J. Tanke, R. W. Dirks, and T. Raap, "FISH and immunocytochemistry: Towards visualising single target molecules in living cells," Curr. Opin. Biotechnol., vol. 16, pp. 49-54, 2005.
15. A. M. Smith, X. Gao, and S. Nie, "Quantum dot nanocrystals for in vivo molecular and cellular imaging," Photochem. Photobiol., vol. 80, pp. 377-385, 2004.
16. M. J. Levene, D. A. Dombeck, K. A. Kasischke, R. P. Molloy, and W. W. Webb, "In vivo multiphoton microscopy of deep brain tissue," J. Neurophysiol., vol. 91, pp. 1908-1912, 2004.
17. B. Ballou, B. C. Lagerholm, L. A. Ernst, M. P. Bruchez, and A. S. Waggoner, "Noninvasive imaging of quantum dots in mice," Bioconjug. Chem., vol. 15, pp. 79-86, 2004.
18. W. Jiang, E. Papa, H. Fischer, S. Mardyani, and W. C. Chan, "Semiconductor quantum dots as contrast agents for whole animal imaging," Trends Biotechnol., vol. 22, pp. 607-609, 2004.
19. X. Gao, L. Yang, J. A. Petros, F. F. Marshall, J. W. Simons, and S. Nie, "In vivo molecular and cellular imaging with quantum dots," Curr. Opin. Biotechnol., vol. 16, pp. 63-72, 2005.
20. N. Y. Morgan, S. English, W. Chen, V. Chernomordik, A. Russo, P. D. Smith, and A. Gandjbakhche, "Real time in vivo non-invasive optical imaging using near-infrared fluorescent quantum dots," Acad. Radiol., vol. 12, pp. 313-323, 2005.
21. A. Hoshino, Y. I. Kawamura, M. Yasuhara, N. Toyama-Sorimachi, K. Ya-mamoto, A. Matsukawa, S. A. Lira, and T. Dohi, "Inhibition of CCL1-CCR8 interaction prevents aggregation of macrophages and development of peritoneal adhesions," J. Immunol., vol. 178, pp. 5296-5304, 2007.
22. M. Green, "Semiconductor quantum dots as biological imaging agents," Angew. Chem. Int. Ed. Engl., vol. 43, pp. 4129-4131, 2004.
23. K. K. Jain, "Nanotechnology in clinical laboratory diagnostics," Clin. Chim. Acta, vol. 358, pp. 37-54, 2005.
24. M. Ebbesen and T. G. Jensen, "Nanomedicine: Techniques, potentials, and ethical implications," J. Biomed. Biotechnol., vol. 2006, pp. 51516-1-51516-11, 2006.
25. R. A. Freitas, Jr., "Nanotechnology, nanomedicine and nanosurgery," Int. J. Surg., vol. 3, pp. 243-246, 2005.
26. S. D. Caruthers, S. A. Wickline, and G. M. Lanza, "Nanotechnological applications in medicine," Curr. Opin. Biotechnol., vol. 18, pp. 26-30, 2007.
27. R. M. Navalakhe and T. D. Nandedkar, "Application of nanotechnology in biomedicine," Indian J. Exp. Biol., vol. 45, pp. 160-165, 2007.
28. M. S. Arayne and N. Sultana, "Review: Nanoparticles in drug delivery for the treatment of cancer," Pak. J. Pharm. Sci., vol. 19, pp. 258-268, 2006.
29. H. Lin and R. H. Datar, "Medical applications of nanotechnology," Nat. Med. J. India, vol. 19, pp. 27-32, 2006.
30. A. Hoshino, T. Ito-Ihara, A. Ishida-Okawara, E. Muso, K. Yamamoto, and K. Suzuki, "Detection of neutrophil MPO in patient with rapidly progressive glumerulonephritis," J. Med. Technol., vol. 50, pp. 1409-1415, 2006.
31. D. S. Lidke, P. Nagy, R. Heintzmann, D. J. Arndt-Jovin, J. N. Post, H. E. Grecco, E. A. Jares-Erijman, and T. M. Jovin, "Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduc tion," Nat. Biotechnol., vol. 22, pp. 198-203, 2004.
32. X. Gao, Y. Cui, R. M. Levenson, L. W. Chung, and S. Nie, "In vivo cancer targeting and imaging with semiconductor quantum dots," Nat. Biotechnol., vol. 22, pp. 969-976, 2004.
33. G. Y. Chen and S. Q. Yao, "Lighting up cancer cells with "dots"," Lancet, vol. 364, pp. 2001-2003, 2004.
34. B. Ballou, L. A. Ernst, and A. S. Waggoner, "Fluorescence imaging of tumors in vivo," Curr. Med. Chem., vol. 12, pp. 795-805, 2005.
35. M. Stroh, J. P. Zimmer, D. G. Duda, T. S. Levchenko, K. S. Cohen, E. B. Brown, D. T. Scadden, V. P. Torchilin, M. G. Bawendi, D. Fukumura, and R. K. Jain, "Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo," Nat. Med., vol. 11, pp. 678-682, 2005.
36. S. Kim, Y. T. Lim, E. G. Soltesz, A. M. De Grand, J. Lee, A. Nakayama, J. A. Parker, T. Mihaljevic, R. G. Laurence, D. M. Dor, L. H. Cohn, M. G. Bawendi, and J. V. Frangioni, "Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping," Nat. Biotechnol., vol. 22, pp. 93-97, 2004.
37. E. G. Soltesz, S. Kim, R. G. Laurence, A. M. DeGrand, C. P. Parungo, D. M. Dor, L. H. Cohn, M. G. Bawendi, J. V. Frangioni, and T. Mihaljevic, "Intraoperative sentinel lymph node mapping of the lung using near-infrared fluorescent quantum dots," Ann. Thorac. Surg., vol. 79, pp. 269-277, 2005 (discussion 269-277).
38. C. P. Parungo, S. Ohnishi, S. W. Kim, S. Kim, R. G. Laurence, E. G. Soltesz, F. Y. Chen, Y. L. Colson, L. H. Cohn, M. G. Bawendi, and J. V. Frangioni, "Intraoperative identification of esophageal sentinel lymph nodes with near-infrared fluorescence imaging," J. Thorac. Cardiovasc. Surg., vol. 129, pp. 844-850, 2005.
39. C. P. Parungo, Y. L. Colson, S. W. Kim, S. Kim, L. H. Cohn, M. G. Bawendi, and J. V. Frangioni, "Sentinel lymph node mapping of the pleural space," Chest, vol. 127, pp. 1799-1804, 2005.
40. M. Takeda, H. Tada, H. Higuchi, Y. Kobayashi, M. Kobayashi, Y. Sakurai, T. Ishida, and N. Ohuchi, "In vivo single molecular imaging and sentinel node navigation by nanotechnology for molecular targeting drug-delivery systems and tailor-made medicine," Breast Cancer, vol. 15, pp. 145-152, 2008.
41. T. C. Harman, P. J. Taylor, M. P. Walsh, and B. E. LaForge, "Quantum dot superlattice thermoelectric materials and devices," Science, vol. 297, pp. 2229-2232, 2002.
42. X. Wu, H. Liu, J. Liu, K. N. Haley, J. A. Treadway, J. P. Larson, N. Ge, F. Peale, andM.P.Bruchez, "Immunofluorescentlabelingofcancer marker Her2 and other cellular targets with semiconductor quantum dots," Nat. Biotechnol., vol. 21, pp. 41-46, 2003.
43. B. Dubertret, P. Skourides, D. J. Norris, V. Noireaux, A. H. Brivanlou, and A. Libchaber, "In vivo imaging of quantum dots encapsulated in phospholipid micelles," Science, vol. 298, pp. 1759-1762, 2002.
44. D. R. Larson, W. R. Zipfel, R. M. Williams, S. W. Clark, M. Bruchez, F. W. Wise, and W. W. Webb, "Water-soluble quantum dots for multiphoton fluorescence imaging in vivo," Science, vol. 300, pp. 1434-1436, 2003.
45. A. Hoshino, K. Fujioka, T. Oku, S. Nakamura, M. Suga, Y. Yamaguchi, K. Suzuki, M. Yasuhara, and K. Yamamoto, "Quantum dots targeted to the assigned organelle in living cells," Microbiol. Immunol., vol. 48, pp. 985-994, 2004.
46. A. Mansson, M. Sundberg, M. Balaz, R. Bunk, I. A. Nicholls, P. Omling, S. Tagerud, and L. Montelius, "In vitro sliding of actin filaments labelled with single quantum dots," Biochem. Biophys. Res. Commun., vol. 314, pp. 529-534, 2004.
47. F. Osaki, T. Kanamori, S. Sando, T. Sera, and Y. Aoyama, "A quantum dot conjugated sugar ball and its cellular uptake. On the size effects of endocytosis in the subviral region," J. Amer. Chem. Soc., vol. 126, pp. 6520-6521, 2004.
48. J. N. Mason, I. D. Tomlinson, S. J. Rosenthal, and R. D. Blakely, "Labeling cell-surface proteins via antibody quantum dot streptavidin conjugates," Methods Mol. Biol., vol. 303, pp. 35-50, 2005.
49. I. D. Tomlinson, J. N. Mason, R. D. Blakely, and S. J. Rosenthal, "Peptideconjugated quantum dots: Imaging the angiotensin type1receptor in living cells," Methods Mol. Biol., vol. 303, pp. 51-60, 2005.
50. A. Matsuno, J. Itoh, S. Takekoshi, T. Nagashima, and R. Y. Osamura, "Three-dimensional imaging of the intracellular localization of growth hormone and prolactin and their mRNA using nanocrystal (Quantum dot) and confocal laser scanning microscopy techniques," J. Histochem. Cytochem., vol. 53, pp. 833-838, 2005.
51. E. L. Bentzen, F. House, T. J. Utley, J. E. Crowe, Jr., and D. W. Wright, "Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes," Nano Lett., vol. 5, pp. 591-595, 2005.
52. A. Agrawal, R. A. Tripp, L. J. Anderson, and S. Nie, "Real-time detection of virus particles and viral protein expression with two-color nanoparticle probes," J. Virol., vol. 79, pp. 8625-8628, 2005.
53. N. Manabe, A. Hoshino, Y. Liang, T. Goto, N. Kato, and K. Yamamoto, "Quantum dot conjugated with medicine as the drug tracer in vitro and in vivo," IEEE Trans. NanoBiosci., vol. 5, no. 4, pp. 263-267, Dec. 2006.
54. S. Yamamoto, N. Manabe, K. Fujioka, A. Hoshino, and K. Yamamoto, "Visualizing vitreous using quantum dots as imaging reagents," IEEE Trans. NanoBiosci., vol. 6, no. 1, pp. 94-98, Mar. 2007.
55. J. L. Bouldin, T. M. Ingle, A. Sengupta, R. Alexander, R. E. Hannigan, and R. A. Buchanan, "Aqueous toxicity and food chain transfer of quantum DotStrade mark in freshwater Algae and Ceriodaphnia dubia," Environ. Toxicol. Chem., vol. 27, no. 9, pp. 1958-1963, 2008.
56. A. Hoshino, N. Manabe, K. Fujioka, K. Suzuki, M. Yasuhara, and K. Yamamoto, "Use of fluorescent quantum dot bioconjugates for cellular imaging of immune cells, cell organelle labeling, and nanomedicine: Surface modification regulates biological function, including cytotoxicity," J. Artif. Organs, vol. 10, pp. 149-157, 2007.
57. R. Hardman, "A toxicologic review of quantum dots: Toxicity depends on physicochemical and environmental factors," Environ. Health Perspect., vol. 114, pp. 165-172, 2006.
58. M. Matsushita, K. Tomizawa, A. Moriwaki, S. T. Li, H. Terada, and H. Matsui, "A high-efficiency protein transduction system demonstrating the role of PKA in long-lasting long-term potentiation," J. Neurosci., vol. 21, pp. 6000-6007, 2001.
59. A. Hoshino, K. Hanaki, K. Suzuki, and K. Yamamoto, "Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse body," Biochem. Biophys. Res. Commun., vol. 314, pp. 46-53, 2004.
60. A. Hoshino, K. Fujioka, T. Oku, M. Suga, Y. F. Sasaki, T. Ohta, M. Yasuhara, K. Suzuki, and K. Yamamoto, "Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification," Nano Lett., vol. 4, pp. 2163-2169, 2004.
61. A. Hoshino, N. Manabe, K. Fujioka, S. Hanada, M. Yasuhara, A. Kondo, and K. Yamamoto, "GFP expression by intracellular gene delivery of GFP-coding fragments using nanocrystal quantum dots," Nanotechnology, vol. 19, pp. 495102-1-495102-12, 2008.
62. A. Zlotnik,O. Yoshie, and H. Nomiyama, "The chemokine and chemokine receptor superfamilies and their molecular evolution," Genome Biol., vol. 7, p. 243, 2006.
63. M. Tang, T. Xing, J. Zeng, H. Wang, C. Li, S. Yin, D. Yan, H. Deng, J. Liu, M. Wang, J. Chen, and D. Y. Ruan, "Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hip-pocampal neurons," Environ. Health Perspect., vol. 116, pp. 915-922, 2008.
64. S. T. Stern, B. S. Zolnik, C. B. McLeland, J. Clogston, J. Zheng, and S. E. McNeil, "Induction of autophagy in porcine kidney cells by quantum dots: A common cellular response to nanomaterials?," Toxicol. Sci., vol. 106, pp. 140-152, 2008.
65. J. G. Rouse, C. M. Haslauer, E. G. Loboa, and N. A. Monteiro-Riviere, "Cyclic tensile strain increases interactions between human epidermal keratinocytes and quantum dot nanoparticles," Toxicol. In Vitro, vol. 22, pp. 491-497, 2008.
66. H. Hemmi, O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, M. Mat-sumoto, K. Hoshino, H. Wagner, K. Takeda, and S. Akira, "A Toll-like receptor recognizes bacterial DNA," Nature, vol. 408, pp. 740-745, 2000.
67. S. S. Diebold, T. Kaisho, H. Hemmi, S. Akira, and C. Reis e Sousa, "Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA," Science, vol. 303, pp. 1529-1531, 2004.
68. E. Latz, A. Schoenemeyer, A. Visintin, K. A. Fitzgerald, B. G. Monks, C. F. Knetter, E. Lien, N. J. Nilsen, T. Espevik, and D. T. Golenbock, "TLR9 signals after translocating from the ER to CpG DNA in the lysosome," Nat. Immunol., vol. 5, pp. 190-198, 2004.