-
1
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007;128:683-692
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
2
-
-
0345357773
-
Gene Silencing in Cancer in Association with Promoter Hypermethylation
-
DOI 10.1056/NEJMra023075
-
Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003;349:2042-2054 (Pubitemid 37448928)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.21
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
3
-
-
33846569960
-
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
-
DOI 10.1038/ng1972, PII NG1972
-
Ohm JE, McGarvey KM, Yu X, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 2007;39:237-242 (Pubitemid 46184356)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 237-242
-
-
Ohm, J.E.1
McGarvey, K.M.2
Yu, X.3
Cheng, L.4
Schuebel, K.E.5
Cope, L.6
Mohammad, H.P.7
Chen, W.8
Daniel, V.C.9
Yu, W.10
Berman, D.M.11
Jenuwein, T.12
Pruitt, K.13
Sharkis, S.J.14
Watkins, D.N.15
Herman, J.G.16
Baylin, S.B.17
-
4
-
-
33846576622
-
Epigenetic stem cell signature in cancer
-
DOI 10.1038/ng1941, PII NG1941
-
Widschwendter M, Fiegl H, Egle D, et al. Epigenetic stem cell signature in cancer. Nat Genet 2007;39:157-158 (Pubitemid 46184343)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 157-158
-
-
Widschwendter, M.1
Fiegl, H.2
Egle, D.3
Mueller-Holzner, E.4
Spizzo, G.5
Marth, C.6
Weisenberger, D.J.7
Campan, M.8
Young, J.9
Jacobs, I.10
Laird, P.W.11
-
5
-
-
33846649587
-
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
-
DOI 10.1038/ng1950, PII NG1950
-
Schlesinger Y, Straussman R, Keshet I, et al. Polycombmediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet 2007;39:232-236 (Pubitemid 46184355)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
Farkash, S.4
Hecht, M.5
Zimmerman, J.6
Eden, E.7
Yakhini, Z.8
Ben-Shushan, E.9
Reubinoff, B.E.10
Bergman, Y.11
Simon, I.12
Cedar, H.13
-
6
-
-
33847084602
-
Genome Regulation by Polycomb and Trithorax Proteins
-
DOI 10.1016/j.cell.2007.02.009, PII S0092867407001900
-
Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G. Genome regulation by polycomb and trithorax proteins. Cell 2007;128:735-745 (Pubitemid 46273581)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 735-745
-
-
Schuettengruber, B.1
Chourrout, D.2
Vervoort, M.3
Leblanc, B.4
Cavalli, G.5
-
7
-
-
4644319204
-
Stem cells and cancer: The polycomb connection
-
DOI 10.1016/j.cell.2004.08.005, PII S0092867404007457
-
Valk-Lingbeek ME, Bruggeman SW, van Lohuizen M. Stem cells and cancer; the polycomb connection. Cell 2004;118:409-418 (Pubitemid 39485661)
-
(2004)
Cell
, vol.118
, Issue.4
, pp. 409-418
-
-
Valk-Lingbeek, M.E.1
Bruggeman, S.W.M.2
Van Lohuizen, M.3
-
8
-
-
0036830642
-
Role of histone H3 lysine 27 methylation in polycomb-group silencing
-
DOI 10.1126/science.1076997
-
Cao R, Wang L, Wang H, et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 2002;298:1039-1043 (Pubitemid 35247314)
-
(2002)
Science
, vol.298
, Issue.5595
, pp. 1039-1043
-
-
Cao, R.1
Wang, L.2
Wang, H.3
Xia, L.4
Erdjument-Bromage, H.5
Tempst, P.6
Jones, R.S.7
Zhang, Y.8
-
9
-
-
3042781030
-
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27
-
DOI 10.1101/gad.1200204
-
Kirmizis A, Bartley SM, Kuzmichev A, et al. Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27. Genes Dev 2004;18:1592-1605 (Pubitemid 38868910)
-
(2004)
Genes and Development
, vol.18
, Issue.13
, pp. 1592-1605
-
-
Kirmizis, A.1
Bartley, S.M.2
Kuzmichev, A.3
Margueron, R.4
Reinberg, D.5
Green, R.6
Farnham, P.J.7
-
10
-
-
32844459336
-
The Polycomb group protein EZH2 directly controls DNA methylation
-
DOI 10.1038/nature04431, PII NATURE04431
-
Vire E, Brenner C, Deplus R, et al. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 2006;439:871-874 (Pubitemid 43255707)
-
(2006)
Nature
, vol.439
, Issue.7078
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
Morey, L.7
Van Eynde, A.8
Bernard, D.9
Vanderwinden, J.-M.10
Bollen, M.11
Esteller, M.12
Di Croce, L.13
De Launoit, Y.14
Fuks, F.15
-
11
-
-
34347233479
-
DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2
-
DOI 10.1158/0008-5472.CAN-06-2029
-
McGarvey KM, Greene E, Fahrner JA, Jenuwein T, Baylin SB. DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2. Cancer Res 2007;67:5097-5102 (Pubitemid 46997244)
-
(2007)
Cancer Research
, vol.67
, Issue.11
, pp. 5097-5102
-
-
McGarvey, K.M.1
Greene, E.2
Fahrner, J.A.3
Jenuwein, T.4
Baylin, S.B.5
-
12
-
-
44349131472
-
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
-
DOI 10.1038/ng.159, PII NG159
-
Kondo Y, Shen L, Cheng AS, et al. Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet 2008;40:741-750 (Pubitemid 351748874)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 741-750
-
-
Kondo, Y.1
Shen, L.2
Cheng, A.S.3
Ahmed, S.4
Boumber, Y.5
Charo, C.6
Yamochi, T.7
Urano, T.8
Furukawa, K.9
Kwabi-Addo, B.10
Gold, D.L.11
Sekido, Y.12
Huang, T.H.-M.13
Issa, J.-P.J.14
-
14
-
-
1342332096
-
Polycomb CBX7 has a unifying role in cellular lifespan
-
DOI 10.1038/ncb1077
-
Gil J, Bernard D, Martinez D, Beach D. Polycomb CBX7 has a unifying role in cellular lifespan. Nat Cell Biol 2004;6:67-72. (Pubitemid 38425732)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.1
, pp. 67-72
-
-
Gil, J.1
Bernard, D.2
Martinez, D.3
Beach, D.4
-
15
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman JG, Merlo A, Mao L, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995;55:4525-4530
-
(1995)
Cancer Res
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
-
16
-
-
34248328001
-
Role of the chromobox protein CBX7 in lymphomagenesis
-
DOI 10.1073/pnas.0608721104
-
Scott CL, Gil J, Hernando E, et al. Role of the chromobox protein CBX7 in lymphomagenesis. Proc Natl Acad Sci U S A 2007;104:5389-5394 (Pubitemid 47175690)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.13
, pp. 5389-5394
-
-
Scott, C.L.1
Gil, J.2
Hernando, E.3
Teruya-Feldstein, J.4
Narita, M.5
Martinez, D.6
Visakorpi, T.7
Mu, D.8
Cordon-Cardo, C.9
Peters, G.10
Beach, D.11
Lowe, S.W.12
-
17
-
-
33645231102
-
Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin
-
Bernstein E, Duncan EM, Masui O, Gil J, Heard E, Allis CD. Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. Mol Cell Biol 2006;26:2560-2569
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2560-2569
-
-
Bernstein, E.1
Duncan, E.M.2
Masui, O.3
Gil, J.4
Heard, E.5
Allis, C.D.6
-
18
-
-
33645751058
-
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
-
McGarvey KM, Fahrner JA, Greene E, Martens J, Jenuwein T, Baylin SB. Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Res 2006;66:3541-3549
-
(2006)
Cancer Res
, vol.66
, pp. 3541-3549
-
-
McGarvey, K.M.1
Fahrner, J.A.2
Greene, E.3
Martens, J.4
Jenuwein, T.5
Baylin, S.B.6
-
19
-
-
34848918829
-
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer
-
DOI 10.1371/journal.pgen.0030157
-
Schuebel KE, Chen W, Cope L, et al. Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. PLoS Genet 2007;3:1709-1723 (Pubitemid 47510263)
-
(2007)
PLoS Genetics
, vol.3
, Issue.9
, pp. 1709-1723
-
-
Schuebel, K.E.1
Chen, W.2
Cope, L.3
Glockner, S.C.4
Suzuki, H.5
Yi, J.-M.6
Chan, T.A.7
Van Neste, L.8
Van Criekinge, W.9
Van Den Bosch, S.10
Van Engeland, M.11
Ting, A.H.12
Jair, K.13
Yu, W.14
Toyota, M.15
Imai, K.16
Ahuja, N.17
Herman, J.G.18
Baylin, S.B.19
-
20
-
-
0026546877
-
A genomic sequencing protocol that yields a positive display of 5-methylcytosi ne residues in individual DNA strands
-
Frommer M, McDonald LE, Millar DS, et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosi ne residues in individual DNA strands. Proc Natl Acad Sci U S A 1992;89:1827-1831
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 1827-1831
-
-
Frommer, M.1
McDonald, L.E.2
Millar, D.S.3
-
21
-
-
61449477534
-
GoldenGate assay for DNA methylation profiling
-
Bibikova M, Fan JB. GoldenGate assay for DNA methylation profiling. Methods Mol Biol 2009;507:149-163
-
(2009)
Methods Mol Biol
, vol.507
, pp. 149-163
-
-
Bibikova, M.1
Fan, J.B.2
-
22
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
DOI 10.1038/416552a
-
Rhee I, Bachman KE, Park BH, et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 2002;416:552-556 (Pubitemid 34288859)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.-W.4
Yen, R.-W.C.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
Baylin, S.B.11
Vogelstein, B.12
-
23
-
-
12144255958
-
Replication-independent chromatin loading of Dnmt1 during G2 and M phases
-
DOI 10.1038/sj.embor.7400295
-
Easwaran HP, Schermelleh L, Leonhardt H, Cardoso MC. Replication- independent chromatin loading of Dnmt1 during G2 and M phases. EMBO Rep 2004;5:1181-1186 (Pubitemid 40103614)
-
(2004)
EMBO Reports
, vol.5
, Issue.12
, pp. 1181-1186
-
-
Easwaran, H.P.1
Schermelleh, L.2
Leonhardt, H.3
Cardoso, M.C.4
-
24
-
-
0024213022
-
Cloning of a mammalian DNA methyltransferase
-
Bestor TH. Cloning of a mammalian DNA methyltransferase. Gene 1988;74:9-12.
-
(1988)
Gene
, vol.74
, pp. 9-12
-
-
Bestor, T.H.1
-
25
-
-
0026439115
-
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
-
Leonhardt H, Page AW, Weier HU, Bestor TH. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 1992;71:865-873
-
(1992)
Cell
, vol.71
, pp. 865-873
-
-
Leonhardt, H.1
Page, A.W.2
Weier, H.U.3
Bestor, T.H.4
-
26
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
DOI 10.1016/S0092-8674(00)81656-6
-
Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999;99:247-257 (Pubitemid 29519904)
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
27
-
-
0037924433
-
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene
-
DOI 10.1016/S1535-6108(02)00234-9
-
Bachman KE, Park BH, Rhee I, et al. Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene. Cancer Cell 2003;3:89-95. (Pubitemid 37443893)
-
(2003)
Cancer Cell
, vol.3
, Issue.1
, pp. 89-95
-
-
Bachman, K.E.1
Park, B.H.2
Rhee, I.3
Rajagopalan, H.4
Herman, J.G.5
Baylin, S.B.6
Kinzler, K.W.7
Vogelstein, B.8
-
28
-
-
0035943709
-
Dnmt3a and Dnmt3b Are Transcriptional Repressors That Exhibit Unique Localization Properties to Heterochromatin
-
DOI 10.1074/jbc.M104661200
-
Bachman KE, Rountree MR, Baylin SB. Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin. J Biol Chem 2001;276:32282-32287 (Pubitemid 37384893)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.34
, pp. 32282-32287
-
-
Bachman, K.E.1
Rountree, M.R.2
Baylin, S.B.3
-
29
-
-
35348982301
-
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
-
DOI 10.1101/gad.1588207
-
Loh YH, Zhang W, Chen X, George J, Ng HH. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate selfrenewal in embryonic stem cells. Genes Dev 2007;21:2545-2557 (Pubitemid 47607666)
-
(2007)
Genes and Development
, vol.21
, Issue.20
, pp. 2545-2557
-
-
Loh, Y.-H.1
Zhang, W.2
Chen, X.3
George, J.4
Ng, H.-H.5
-
30
-
-
0037064088
-
A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation
-
DOI 10.1074/jbc.M205312200
-
Chen T, Ueda Y, Xie S, Li E. A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation. J Biol Chem 2002;277:38746-38754 (Pubitemid 35154737)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.41
, pp. 38746-38754
-
-
Chen, T.1
Ueda, Y.2
Xie, S.3
Li, E.4
-
31
-
-
33751209468
-
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
-
DOI 10.1101/gad.1463706
-
Esteve PO, Chin HG, Smallwood A, et al. Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Genes Dev 2006;20:3089-3103 (Pubitemid 44790625)
-
(2006)
Genes and Development
, vol.20
, Issue.22
, pp. 3089-3103
-
-
Esteve, P.-O.1
Hang, G.C.2
Smallwood, A.3
Feehery, G.R.4
Gangisetty, O.5
Karpf, A.R.6
Carey, M.F.7
Pradhan, S.8
-
32
-
-
55549145072
-
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
-
Epsztejn-Litman S, Feldman N, Abu-Remaileh M, et al. De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes. Nat Struct Mol Biol 2008;15:1176-1183
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1176-1183
-
-
Epsztejn-Litman, S.1
Feldman, N.2
Abu-Remaileh, M.3
-
33
-
-
0021447637
-
Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro
-
Andrews PW. Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro . Dev Biol 1984;103:285-293
-
(1984)
Dev Biol
, vol.103
, pp. 285-293
-
-
Andrews, P.W.1
-
34
-
-
0022640511
-
Differentiation of TERA-2 human embryonal carcinoma cells into neurons and HCMV permissive cells. Induction by agents other than retinoic acid
-
Andrews PW, Gonczol E, Plotkin SA, Dignazio M, Oosterhuis JW. Differentiation of TERA-2 human embryonal carcinoma cells into neurons and HCMV permissive cells. Induction by agents other than retinoic acid. Differentiation 1986;31:119-126
-
(1986)
Differentiation
, vol.31
, pp. 119-126
-
-
Andrews, P.W.1
Gonczol, E.2
Plotkin, S.A.3
Dignazio, M.4
Oosterhuis, J.W.5
-
35
-
-
33646870495
-
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
-
Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 2006;20:1123-1136
-
(2006)
Genes Dev
, vol.20
, pp. 1123-1136
-
-
Bracken, A.P.1
Dietrich, N.2
Pasini, D.3
Hansen, K.H.4
Helin, K.5
-
36
-
-
33646865180
-
Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells
-
DOI 10.1016/j.cell.2006.02.043, PII S0092867406003849
-
Lee TI, Jenner RG, Boyer LA, et al. Control of developmental regulators by polycomb in human embryonic stem cells. Cell 2006;125:301-313 (Pubitemid 44313811)
-
(2006)
Cell
, vol.125
, Issue.2
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
Guenther, M.G.4
Levine, S.S.5
Kumar, R.M.6
Chevalier, B.7
Johnstone, S.E.8
Cole, M.F.9
Isono, K.-I.10
Koseki, H.11
Fuchikami, T.12
Abe, K.13
Murray, H.L.14
Zucker, J.P.15
Yuan, B.16
Bell, G.W.17
Herbolsheimer, E.18
Hannett, N.M.19
Sun, K.20
Odom, D.T.21
Otte, A.P.22
Volkert, T.L.23
Bartel, D.P.24
Melton, D.A.25
Gifford, D.K.26
Jaenisch, R.27
Young, R.A.28
more..
-
37
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
DOI 10.1038/nature06008, PII NATURE06008
-
Mikkelsen TS, Ku M, Jaffe DB, et al. Genome-wide maps of chroma tin state in pluripotent and lineagecommitted cells. Nature 2007;448:553-560 (Pubitemid 47206934)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
Lieberman, E.5
Giannoukos, G.6
Alvarez, P.7
Brockman, W.8
Kim, T.-K.9
Koche, R.P.10
Lee, W.11
Mendenhall, E.12
O'Donovan, A.13
Presser, A.14
Russ, C.15
Xie, X.16
Meissner, A.17
Wernig, M.18
Jaenisch, R.19
Nusbaum, C.20
Lander, E.S.21
Bernstein, B.E.22
more..
-
38
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden M, Frommer M. CpG islands in vertebrate genomes. J Mol Biol 1987;196:261-282
-
(1987)
J Mol Biol
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
39
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, Mikkelsen TS, Xie X, et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006;125:315-326
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
-
40
-
-
0037215568
-
Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer
-
DOI 10.1128/MCB.23.1.206-215.2003
-
Kondo Y, Shen L, Issa JP. Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. Mol Cell Biol 2003;23:206-215 (Pubitemid 36008514)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.1
, pp. 206-215
-
-
Kondo, Y.1
Shen, L.2
Issa, J.-P.J.3
-
41
-
-
0037112369
-
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′- deoxycytidine
-
Nguyen CT, Weisenberger DJ, Velicescu M, et al. Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′-deoxycytidine. Cancer Res 2002;62:6456-6461 (Pubitemid 35364106)
-
(2002)
Cancer Research
, vol.62
, Issue.22
, pp. 6456-6461
-
-
Nguyen, C.T.1
Weisenberger, D.J.2
Velicescu, M.3
Gonzales, F.A.4
Lin, J.C.Y.5
Liang, G.6
Jones, P.A.7
-
42
-
-
0036149471
-
Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium
-
DOI 10.1006/dbio.2001.0424
-
Jacobsen CM, Narita N, Bielinska M, Syder AJ, Gordon JI, Wilson DB. Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium. Dev Biol 2002;241:34-46. (Pubitemid 34066760)
-
(2002)
Developmental Biology
, vol.241
, Issue.1
, pp. 34-46
-
-
Jacobsen, C.M.1
Narita, N.2
Bielinska, M.3
Syder, A.J.4
Gordon, J.I.5
Wilson, D.B.6
-
44
-
-
42349108108
-
Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer
-
DOI 10.1158/0008-5472.CAN-07-6349
-
Zhang W, Glockner SC, Guo M, et al. Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res 2008;68:2764-2772 (Pubitemid 351556274)
-
(2008)
Cancer Research
, vol.68
, Issue.8
, pp. 2764-2772
-
-
Zhang, W.1
Glockner, S.C.2
Guo, M.3
Machida, E.O.4
Wang, D.H.5
Easwaran, H.6
Van Neste, L.7
Herman, J.G.8
Schuebel, K.E.9
Watkins, D.N.10
Ahuja, N.11
Baylin, S.B.12
-
45
-
-
0033919595
-
DNMT1 forms a complex with rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
-
Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP. DNMT1 forms a complex with rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat Genet 2000;25:338-342
-
(2000)
Nat Genet
, vol.25
, pp. 338-342
-
-
Robertson, K.D.1
Ait-Si-Ali, S.2
Yokochi, T.3
Wade, P.A.4
Jones, P.L.5
Wolffe, A.P.6
-
46
-
-
0033988813
-
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
-
DOI 10.1038/71750
-
Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T. DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet 2000;24:88-91. (Pubitemid 30041428)
-
(2000)
Nature Genetics
, vol.24
, Issue.1
, pp. 88-91
-
-
Fuks, F.1
Burgers, W.A.2
Brehm, A.3
Hughes-Davies, L.4
Kouzarides, T.5
-
47
-
-
0035873225
-
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
-
DOI 10.1093/emboj/20.10.2536
-
Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T. Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. EMBO J 2001;20:2536-2544 (Pubitemid 32452872)
-
(2001)
EMBO Journal
, vol.20
, Issue.10
, pp. 2536-2544
-
-
Fuks, F.1
Burgers, W.A.2
Godin, N.3
Kasai, M.4
Kouzarides, T.5
-
48
-
-
0033945861
-
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
-
Rountree MR, Bachman KE, Baylin SB. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet 2000;25:269-277
-
(2000)
Nat Genet
, vol.25
, pp. 269-277
-
-
Rountree, M.R.1
Bachman, K.E.2
Baylin, S.B.3
-
49
-
-
38049155825
-
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
-
Yu W, Gius D, Onyango P, et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 2008;451:202-206
-
(2008)
Nature
, vol.451
, pp. 202-206
-
-
Yu, W.1
Gius, D.2
Onyango, P.3
|