Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium

Developmental Biology

Volumn 241, Issue 1, 2002, Pages 34-46

  Jacobsen, Christina M ^a   Narita, Naoko ^b   Bielinska, Malgorzata ^a   Syder, Andrew J ^a   Gordon, Jeffrey I ^a   Wilson, David B ^a  

^a ST LOUIS CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Endoderm; H+, K+ ATPase; Sonic hedgehog; Stomach; Transcription factor

Indexed keywords

BINDING PROTEIN; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CHIMERA; CYTOLOGY; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; ENDODERM; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC ENGINEERING; IMMUNOHISTOCHEMISTRY; INTESTINE MALFORMATION; MORULA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH EPITHELIUM;

ERINACEIDAE;

EID: 0036149471     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0424     Document Type: Article

References (85)

1. Transcription factor GATA-6 activates expression of gastroprotective trefoil genes TFF1 and TFF2
2. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
3. Mouse GATA-4: A retinoic acid-inducible GATA-binding transcription factor expressed in endodermal derivatives and heart
4. Apolipoprotein J expression at fluid-tissue interfaces: Potential role in barrier cytoprotection
5. Distinct expression of CDX2 and GATA4/5, development-related genes, in human gastric cancer cell lines
6. Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart
7. Distinct roles for visceral endoderm during embryonic mouse development
8. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
9. GATA transcription factors as potentiators of gut endoderm differentiation
10. Repressive and restrictive mesodermal interactions with gut endoderm: Possible relation to Meckel's Diverticulum
11. Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping
12. Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors
13. HNF3beta and GATA-4 transactivate the liver-enriched homeobox gene, Hex
14. The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis
15. tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman
16. Lectins are sensitive tools for defining the differentiation programs of mouse gut epithelial cell lineages
17. Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice
18. Direct visualization of the elt-2 gut-specific GATA factor binding to a target promoter inside the living Caenorhabditis elegans embryo
19. Anterior endoderm is sufficient to rescue foregut apoptosis and heart tube morphogenesis in an embryo lacking retinoic acid
20. Endoderm development: From patterning to organogenesis
21. Pepsinogen gene transcription induced in heterologous epithelial-mesenchymal recombinations of chicken endoderms and glandular stomach mesenchyme
22. Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development
23. The GATA-4 transcription factor transactivates the cardiac-specific troponin C promoter-enhancer in non-muscle cells
24. The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation
25. Cell lineage relationship in the stomach of normal and genetically manipulated mice
26. Gastric epithelial morphogenesis in normal and transgenic mice
27. Expression and regulation of transcription factors GATA-4 and GATA-6 in developing mouse testis
28. Reciprocal changes in the expression of transcription factors GATA-4 and GATA-6 accompany adrenocortical tumorigenesis in mice and humans
29. Activin receptor patterning of foregut organogenesis
30. In vitro analysis of mesenchymal influences on the differentiation of stomach epithelial cells of the chicken embryo
31. Retinoid signaling required for normal heart development regulates GATA-4 in a pathway distinct from cardiomyocyte differentiation
32. The transcription factor GATA6 is essential for early extraembryonic development
33. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
34. Transcription factors GATA-4 and GATA-6 and a GATA family cofactor, FOG-2, are expressed in human ovary and sex cord-derived ovarian tumors
35. A new timnan-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm
36. Stimulation of activin receptor II signaling pathways inhibits differentiation of multiple gastric epithelial lineages
37. Simian virus 40 T antigen-induced amplification of pre-parietal cells in transgenic mice. Effects on other gastric epithelial cell lineages and evidence for a p53-independent apoptotic mechanism that operates in a committed progenitor
38. Diphtheria toxin-mediated ablation of parietal cells in the stomach of transgenic mice
39. A minimal critical region of the 8p22-23 amplicon in esophageal adenocarcinomas defined using sequence tagged site-amplification mapping and quantitative polymerase chain reaction includes the GATA-4 gene
40. Use of transgenic mice to study regulation of gene expression in the parietal cell lineage of gastric units
41. Different phenotypes for mice deficient in either activins or activin receptor type II
42. The zinc finger-containing transcription factors GATA-4, -5, and -6: Ubiquitously expressed regulators of tissue-specific gene expression
43. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
44. Abnormalities of the genitourinary tract in female mice lacking GATA5
45. Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4
46. GATA-6: A zinc finger transcription factor that is expressed in multiple cell lineages derived from the lateral mesoderm
47. The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially-regulated by GATA-6 and GATA-4 in the visceral endoderm
48. GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo
49. +-ATPase are specifically transcribed in gastric parietal cells
50. Cardiomyocyte differentiation by GATA-4 deficient embryonic stem cells
51. Wild type endoderm abrogates the ventral developmental defects associated with GATA-4 deficiency in the mouse
52. The gene for transcription factor GATA-6 resides on mouse chromosome 18 and is expressed in myocardium and vascular smooth muscle
53. BMPs are necessary for stomach gland formation in the chicken embryo: A study using virally induced BMP-2 and Noggin expression
54. +-ATPase genes by gastric GATA binding proteins
55. Lineage and clonal development of gastric glands
56. Homeobox gene product Nkx 6.1 immunoreactivity in nuclei of endocrine cells of rat and mouse stomach
57. Production of chimeras and genetically defined offspring from targeted ES cells
58. The mouse fetoprotein transcription factor (FTF) gene promoter is regulated by three GATA elements with tandem E-box and Nkx motifs, and FTF in turn activates the HNF3B, HNF4a and HNF1a gene promoters
59. Hedgehog signals regulate multiple aspects of gastrointestinal development
60. Chicken Nkx-2.8: A novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm
61. A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila
62. Gata5 is required for the development of the heart and endoderm in zebrafish
63. Multiple roles for Gata5 in zebrafish endoderm formation
64. Induction of the mesendoderm in the zebrafish germ ring by yolk cell-derived TGF-beta family signals and discrimination of mesoderm and endoderm by FGF
65. Role for cGATA-5 in transcriptional regulation of the embryonic chicken pepsinogen gene by epithelial-mesenchymal interactions in the developing chicken stomach
66. Analysis of temporal expression pattern and cis-regulatory sequences of chicken pepsinogen A and C
67. GATA-4 and nkx-2.5 coactivate nkx-2 DNA binding targets: Role for regulating early cardiac gene expression
68. Action of the Caenorhabditis elegans GATA factor END-1 in Xenopus suggests that similar mechanisms initiate endoderm development in ecdysozoa and vertebrates
69. Transcription factor GATA-4 is expressed in pediatric yolk sac tumors
70. Roles of BMP signaling and Nkx2.5 in patterning at the chick midgut-foregut boundary
71. Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro
72. The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium
73. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
74. Helicobacter pylori attaches to NeuAc alpha 2,3Gal beta 1,4 glycoconjugates produced in the stomach of transgenic mice lacking parietal cells
75. Tissue interaction regulates expression of a spasmolytic polypeptide gene in chicken stomach epithelium
76. Gastric DNA-binding proteins recognize upstream sequence motifs of parietal cell-specific genes
77. Formation of the definitive endoderm in mouse is a Smad2-dependent process
78. Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter
79. A role for GATA5 in Xenopus endoderm specification
80. Vertebrate endoderm development
81. A two-step model for the fate determination of presumptive endodermal blastomeres in Xenopus embryos
82. Developmental competence of the gut endoderm: Genetic potentiation by GATA and HNF3/fork head proteins
83. Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus
84. end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos