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Volumn 39, Issue 12, 2009, Pages 1305-1317

Flow cytometric analysis and microsatellite genotyping reveal extensive DNA content variation in Trypanosoma cruzi populations and expose contrasts between natural and experimental hybrids

Author keywords

DNA content; Genetic exchange; Hybridisation; Microsatellite; Ploidy; Trypanosoma cruzi

Indexed keywords

DNA; NUCLEOTIDE;

EID: 68049124799     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2009.04.001     Document Type: Article
Times cited : (102)

References (101)
  • 1
    • 0037854703 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms of the Trypanosoma cruzi MSH2 gene support the existence of three phylogenetic lineages presenting differences in mismatch-repair efficiency
    • Augusto-Pinto L., Teixeira S.M.R., Pena S.D.J., and Machado C.R. Single-nucleotide polymorphisms of the Trypanosoma cruzi MSH2 gene support the existence of three phylogenetic lineages presenting differences in mismatch-repair efficiency. Genetics 164 (2003) 117-126
    • (2003) Genetics , vol.164 , pp. 117-126
    • Augusto-Pinto, L.1    Teixeira, S.M.R.2    Pena, S.D.J.3    Machado, C.R.4
  • 2
    • 0034071224 scopus 로고    scopus 로고
    • Population structure and genetic typing of Trypanosoma cruzi, the agent of Chagas disease: a multilocus enzyme electrophoresis approach
    • Barnabé C., Brisse S., and Tibayrenc M. Population structure and genetic typing of Trypanosoma cruzi, the agent of Chagas disease: a multilocus enzyme electrophoresis approach. Parasitology 120 (2000) 513-526
    • (2000) Parasitology , vol.120 , pp. 513-526
    • Barnabé, C.1    Brisse, S.2    Tibayrenc, M.3
  • 3
    • 0035936871 scopus 로고    scopus 로고
    • Trypanosoma cruzi: presence of the two major phylogenetic lineages and of several lesser discrete typing units (DTUs) in Chile and Paraguay
    • Barnabé C., Neubauer K., Solari A., and Tibayrenc M. Trypanosoma cruzi: presence of the two major phylogenetic lineages and of several lesser discrete typing units (DTUs) in Chile and Paraguay. Acta Trop. 78 (2001) 127-137
    • (2001) Acta Trop. , vol.78 , pp. 127-137
    • Barnabé, C.1    Neubauer, K.2    Solari, A.3    Tibayrenc, M.4
  • 4
    • 0035676034 scopus 로고    scopus 로고
    • Trypanosoma cruzi: a considerable phylogenetic divergence indicates that the agent of Chagas disease is indigenous to the native fauna of the United States
    • Barnabé C., Yaeger R., Pung O., and Tibayrenc M. Trypanosoma cruzi: a considerable phylogenetic divergence indicates that the agent of Chagas disease is indigenous to the native fauna of the United States. Exp. Parasitol. 99 (2001) 73-79
    • (2001) Exp. Parasitol. , vol.99 , pp. 73-79
    • Barnabé, C.1    Yaeger, R.2    Pung, O.3    Tibayrenc, M.4
  • 5
    • 0038577154 scopus 로고    scopus 로고
    • Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains
    • Bennett R.J., and Johnson A.D. Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains. EMBO J. 22 (2003) 2505-2515
    • (2003) EMBO J. , vol.22 , pp. 2505-2515
    • Bennett, R.J.1    Johnson, A.D.2
  • 8
    • 33645867686 scopus 로고    scopus 로고
    • Comparative karyotyping as a tool for genome structure analysis of Trypanosoma cruzi
    • Branche C., Ochaya S., Aslund L., and Andersson B. Comparative karyotyping as a tool for genome structure analysis of Trypanosoma cruzi. Mol. Biochem. Parasitol. 147 (2006) 30-38
    • (2006) Mol. Biochem. Parasitol. , vol.147 , pp. 30-38
    • Branche, C.1    Ochaya, S.2    Aslund, L.3    Andersson, B.4
  • 9
    • 0025980624 scopus 로고
    • An isoenzyme study of naturally occurring clones of Trypanosoma cruzi isolated from both sides of the West Andes highland
    • Brenière S.F., Braquemond P., Solari A., Agnèse J.F., and Tibayrenc M. An isoenzyme study of naturally occurring clones of Trypanosoma cruzi isolated from both sides of the West Andes highland. Trans. R. Soc. Trop. Med. Hyg. 85 (1991) 62-66
    • (1991) Trans. R. Soc. Trop. Med. Hyg. , vol.85 , pp. 62-66
    • Brenière, S.F.1    Braquemond, P.2    Solari, A.3    Agnèse, J.F.4    Tibayrenc, M.5
  • 12
    • 0004806921 scopus 로고    scopus 로고
    • A phylogenetic analysis of the Trypanosoma cruzi genome project CL Brener reference strain by multilocus enzyme electrophoresis and multiprimer random amplified polymorphic DNA fingerprinting
    • Brisse S., Barnabé C., Banuls A.-L., Sidibe I., Noel S., and Tibayrenc M. A phylogenetic analysis of the Trypanosoma cruzi genome project CL Brener reference strain by multilocus enzyme electrophoresis and multiprimer random amplified polymorphic DNA fingerprinting. Mol. Biochem. Parasitol. 92 (1998) 253-263
    • (1998) Mol. Biochem. Parasitol. , vol.92 , pp. 253-263
    • Brisse, S.1    Barnabé, C.2    Banuls, A.-L.3    Sidibe, I.4    Noel, S.5    Tibayrenc, M.6
  • 13
    • 0033954610 scopus 로고    scopus 로고
    • Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis
    • Brisse S., Barnabé C., and Tibayrenc M. Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis. Int. J. Parasitol. 30 (2000) 35-44
    • (2000) Int. J. Parasitol. , vol.30 , pp. 35-44
    • Brisse, S.1    Barnabé, C.2    Tibayrenc, M.3
  • 14
    • 0034881536 scopus 로고    scopus 로고
    • Characterisation of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages
    • Brisse S., Verhoef J., and Tibayrenc M. Characterisation of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages. Int. J. Parasitol. 31 (2001) 1218-1226
    • (2001) Int. J. Parasitol. , vol.31 , pp. 1218-1226
    • Brisse, S.1    Verhoef, J.2    Tibayrenc, M.3
  • 16
    • 0032487732 scopus 로고    scopus 로고
    • Conserved linkage groups associated with large-scale chromosomal rearrangements between Old World and New World Leishmania genomes
    • Britto C., Ravel C., Bastien P., Blaineau C., Pagès M., Dedet J.-P., and Wincker P. Conserved linkage groups associated with large-scale chromosomal rearrangements between Old World and New World Leishmania genomes. Gene 222 (1998) 107-117
    • (1998) Gene , vol.222 , pp. 107-117
    • Britto, C.1    Ravel, C.2    Bastien, P.3    Blaineau, C.4    Pagès, M.5    Dedet, J.-P.6    Wincker, P.7
  • 17
    • 33748280640 scopus 로고    scopus 로고
    • Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length
    • Callejas S., Leech V., Reitter C., and Melville S. Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length. Genome Res. 16 (2006) 1109-1118
    • (2006) Genome Res. , vol.16 , pp. 1109-1118
    • Callejas, S.1    Leech, V.2    Reitter, C.3    Melville, S.4
  • 19
    • 0029868150 scopus 로고    scopus 로고
    • Genetic exchange as a possible source of genomic diversity in sylvatic populations of Trypanosoma cruzi
    • Carrasco H., Frame I., Valente S., and Miles M. Genetic exchange as a possible source of genomic diversity in sylvatic populations of Trypanosoma cruzi. Am. J. Trop. Med. Hyg. 54 (1996) 418-424
    • (1996) Am. J. Trop. Med. Hyg. , vol.54 , pp. 418-424
    • Carrasco, H.1    Frame, I.2    Valente, S.3    Miles, M.4
  • 21
  • 22
    • 0027410144 scopus 로고
    • Plasticity in chromosome number and testing of essential genes in Leishmania by targeting
    • Cruz A.K., Titus R., and Beverley S.M. Plasticity in chromosome number and testing of essential genes in Leishmania by targeting. Proc. Natl. Acad. Sci. USA 90 (1993) 1599-1603
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1599-1603
    • Cruz, A.K.1    Titus, R.2    Beverley, S.M.3
  • 24
    • 33748641580 scopus 로고    scopus 로고
    • Novel cell biology of Trypanosoma cruzi
    • American Trypanosomiasis. Tyler K.M., and Miles M.A. (Eds), Springer, Boston
    • de Souza W. Novel cell biology of Trypanosoma cruzi. In: Tyler K.M., and Miles M.A. (Eds). American Trypanosomiasis. World Class Parasites vol. 7 (2003), Springer, Boston 13-24
    • (2003) World Class Parasites , vol.7 , pp. 13-24
    • de Souza, W.1
  • 27
    • 0030926411 scopus 로고    scopus 로고
    • Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages
    • Dumas C., Ouellette M., Tovar J., Cunningham M., Fairlamb A., Tamar S., Olivier M., and Papadopoulou B. Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages. EMBO J. 16 (1997) 2590-2598
    • (1997) EMBO J. , vol.16 , pp. 2590-2598
    • Dumas, C.1    Ouellette, M.2    Tovar, J.3    Cunningham, M.4    Fairlamb, A.5    Tamar, S.6    Olivier, M.7    Papadopoulou, B.8
  • 28
    • 0020429209 scopus 로고
    • Trypanosoma cruzi: flow cytometric analysis. I. Analysis of total DNA/organism by means of mithramycin-induced fluorescence
    • Dvorak J., Hall T., Crane M., Engel J., McDaniel J., and Uriegas R. Trypanosoma cruzi: flow cytometric analysis. I. Analysis of total DNA/organism by means of mithramycin-induced fluorescence. J. Protozool. 29 (1982) 430-437
    • (1982) J. Protozool. , vol.29 , pp. 430-437
    • Dvorak, J.1    Hall, T.2    Crane, M.3    Engel, J.4    McDaniel, J.5    Uriegas, R.6
  • 30
    • 0023088917 scopus 로고
    • Trypanosoma cruzi exhibits inter- and intra-strain heterogeneity in molecular karyotype and chromosomal gene location
    • Engman D.M., Reddy L.V., Donelson J.E., and Kirchhoff L.V. Trypanosoma cruzi exhibits inter- and intra-strain heterogeneity in molecular karyotype and chromosomal gene location. Mol. Biochem. Parasitol. 22 (1987) 115-123
    • (1987) Mol. Biochem. Parasitol. , vol.22 , pp. 115-123
    • Engman, D.M.1    Reddy, L.V.2    Donelson, J.E.3    Kirchhoff, L.V.4
  • 31
    • 45149091409 scopus 로고    scopus 로고
    • The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains
    • Forche A., Alby K., Schaefer D., Johnson A.D., Berman J., and Bennett R.J. The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains. PLoS Biol. 6 (2008) e110
    • (2008) PLoS Biol. , vol.6
    • Forche, A.1    Alby, K.2    Schaefer, D.3    Johnson, A.D.4    Berman, J.5    Bennett, R.J.6
  • 33
    • 33749420389 scopus 로고    scopus 로고
    • Genomic convergence toward diploidy in Saccharomyces cerevisiae
    • Gerstein A.C., Chun H.-J.E., Grant A., and Otto S.P. Genomic convergence toward diploidy in Saccharomyces cerevisiae. PLoS Genet. 2 (2006) e145
    • (2006) PLoS Genet. , vol.2
    • Gerstein, A.C.1    Chun, H.-J.E.2    Grant, A.3    Otto, S.P.4
  • 34
    • 40949087238 scopus 로고    scopus 로고
    • Ploidy reduction in Saccharomyces cerevisiae
    • Gerstein A.C., McBride R.M., and Otto S.P. Ploidy reduction in Saccharomyces cerevisiae. Biol. Lett. 4 (2008) 91-94
    • (2008) Biol. Lett. , vol.4 , pp. 91-94
    • Gerstein, A.C.1    McBride, R.M.2    Otto, S.P.3
  • 35
    • 0022729122 scopus 로고
    • The karyotype and ploidy of Trypanosoma cruzi
    • Gibson W., and Miles M. The karyotype and ploidy of Trypanosoma cruzi. EMBO J. 5 (1986) 1299-1305
    • (1986) EMBO J. , vol.5 , pp. 1299-1305
    • Gibson, W.1    Miles, M.2
  • 36
    • 0024821472 scopus 로고
    • Analysis of a genetic cross between Trypanosoma brucei rhodesiense and T. b. brucei
    • Gibson W. Analysis of a genetic cross between Trypanosoma brucei rhodesiense and T. b. brucei. Parasitology 99 (1989) 391-402
    • (1989) Parasitology , vol.99 , pp. 391-402
    • Gibson, W.1
  • 37
    • 0026018624 scopus 로고
    • Genetic exchange in Trypanosoma brucei brucei: variable chromosomal location of housekeeping genes in different trypanosome stocks
    • Gibson W., and Garside L. Genetic exchange in Trypanosoma brucei brucei: variable chromosomal location of housekeeping genes in different trypanosome stocks. Mol. Biochem. Parasitol. 45 (1991) 77-89
    • (1991) Mol. Biochem. Parasitol. , vol.45 , pp. 77-89
    • Gibson, W.1    Garside, L.2
  • 38
    • 0026550312 scopus 로고
    • Trisomy and chromosome size changes in hybrid trypanosomes from a genetic cross between Trypanosoma brucei rhodesiense and T. b. brucei
    • Gibson W., Garside L., and Bailey M. Trisomy and chromosome size changes in hybrid trypanosomes from a genetic cross between Trypanosoma brucei rhodesiense and T. b. brucei. Mol. Biochem. Parasitol. 51 (1992) 189-199
    • (1992) Mol. Biochem. Parasitol. , vol.51 , pp. 189-199
    • Gibson, W.1    Garside, L.2    Bailey, M.3
  • 39
    • 0028356257 scopus 로고
    • Genetic exchange in Trypanosoma brucei: evidence for meiosis from analysis of a cross between drug-resistant transformants
    • Gibson W., and Bailey M. Genetic exchange in Trypanosoma brucei: evidence for meiosis from analysis of a cross between drug-resistant transformants. Mol. Biochem. Parasitol. 64 (1994) 241-252
    • (1994) Mol. Biochem. Parasitol. , vol.64 , pp. 241-252
    • Gibson, W.1    Bailey, M.2
  • 40
    • 0030937089 scopus 로고    scopus 로고
    • Intraclonal mating in Trypanosoma brucei is associated with out-crossing
    • Gibson W., Winters K., Mizen G., Kearns J., and Bailey M. Intraclonal mating in Trypanosoma brucei is associated with out-crossing. Microbiology 143 (1997) 909-920
    • (1997) Microbiology , vol.143 , pp. 909-920
    • Gibson, W.1    Winters, K.2    Mizen, G.3    Kearns, J.4    Bailey, M.5
  • 41
    • 48749114495 scopus 로고    scopus 로고
    • The use of yellow fluorescent hybrids to indicate mating in Trypanosoma brucei
    • Gibson W., Peacock L., Ferris V., Williams K., and Bailey M. The use of yellow fluorescent hybrids to indicate mating in Trypanosoma brucei. Parasites Vectors 1 (2008) 4
    • (2008) Parasites Vectors , vol.1 , pp. 4
    • Gibson, W.1    Peacock, L.2    Ferris, V.3    Williams, K.4    Bailey, M.5
  • 42
    • 85078505418 scopus 로고    scopus 로고
    • Improved flow cytometric analysis of the budding yeast cell cycle
    • Haase S., and Reed S. Improved flow cytometric analysis of the budding yeast cell cycle. Cell cycle 1 (2002) 132-136
    • (2002) Cell cycle , vol.1 , pp. 132-136
    • Haase, S.1    Reed, S.2
  • 47
    • 33744486308 scopus 로고    scopus 로고
    • Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria
    • Hotez P.J., Molyneux D.H., Fenwick A., Ottesen E., Ehrlich Sachs S., and Sachs J.D. Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Med. 3 (2006) e102
    • (2006) PLoS Med. , vol.3
    • Hotez, P.J.1    Molyneux, D.H.2    Fenwick, A.3    Ottesen, E.4    Ehrlich Sachs, S.5    Sachs, J.D.6
  • 48
    • 0034647487 scopus 로고    scopus 로고
    • Evidence for mating of the "asexual" yeast Candida albicans in a mammalian host
    • Hull C.M., Raisner R.M., and Johnson A.D. Evidence for mating of the "asexual" yeast Candida albicans in a mammalian host. Science 289 (2000) 307-310
    • (2000) Science , vol.289 , pp. 307-310
    • Hull, C.M.1    Raisner, R.M.2    Johnson, A.D.3
  • 49
    • 0032077295 scopus 로고    scopus 로고
    • Relation between variation in copy number of ribosomal RNA encoding genes and size of harbouring chromosomes in Leishmania of subgenus Viannia
    • Inga R., De Doncker S., Gomez J., Lopez M., Garcia R., Le Ray D., Arevalo J., and Dujardin J.-C. Relation between variation in copy number of ribosomal RNA encoding genes and size of harbouring chromosomes in Leishmania of subgenus Viannia. Mol. Biochem. Parasitol. 92 (1998) 219-228
    • (1998) Mol. Biochem. Parasitol. , vol.92 , pp. 219-228
    • Inga, R.1    De Doncker, S.2    Gomez, J.3    Lopez, M.4    Garcia, R.5    Le Ray, D.6    Arevalo, J.7    Dujardin, J.-C.8
  • 51
    • 0030888619 scopus 로고    scopus 로고
    • Wide variation in DNA content among isolates of Trypanosoma brucei ssp
    • Kanmogne G.D., Bailey M., and Gibson W.C. Wide variation in DNA content among isolates of Trypanosoma brucei ssp. Acta Trop. 63 (1997) 75-87
    • (1997) Acta Trop. , vol.63 , pp. 75-87
    • Kanmogne, G.D.1    Bailey, M.2    Gibson, W.C.3
  • 52
    • 0033119277 scopus 로고    scopus 로고
    • Size-polymorphism of mini-exon gene-bearing chromosomes among natural populations of Leishmania, subgenus Viannia
    • Kebede A., De Doncker S., Arevalo J., Le Ray D., and Dujardin J.C. Size-polymorphism of mini-exon gene-bearing chromosomes among natural populations of Leishmania, subgenus Viannia. Int. J. Parasitol. 29 (1999) 549-557
    • (1999) Int. J. Parasitol. , vol.29 , pp. 549-557
    • Kebede, A.1    De Doncker, S.2    Arevalo, J.3    Le Ray, D.4    Dujardin, J.C.5
  • 53
    • 75949146309 scopus 로고
    • The number of alleles that can be maintained in a finite population
    • Kimura M., and Crow J.F. The number of alleles that can be maintained in a finite population. Genetics 49 (1964) 725-738
    • (1964) Genetics , vol.49 , pp. 725-738
    • Kimura, M.1    Crow, J.F.2
  • 54
    • 67249129142 scopus 로고    scopus 로고
    • Llewellyn, M.S., Miles, M.A., Carrasco, H.J., Lewis, M.D., Yeo, M., Vargas, J., Torrico, F., Diosque, P., Valente, V., Valente, S.A., Gaunt, M.W., 2009. Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection. PLoS Pathog 5, e1000410.
    • Llewellyn, M.S., Miles, M.A., Carrasco, H.J., Lewis, M.D., Yeo, M., Vargas, J., Torrico, F., Diosque, P., Valente, V., Valente, S.A., Gaunt, M.W., 2009. Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection. PLoS Pathog 5, e1000410.
  • 55
    • 0035912819 scopus 로고    scopus 로고
    • Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi
    • Machado C.A., and Ayala F.J. Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi. Proc. Natl. Acad. Sci. USA 98 (2001) 7396-7401
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7396-7401
    • Machado, C.A.1    Ayala, F.J.2
  • 57
    • 22844441538 scopus 로고    scopus 로고
    • Allelic segregation and independent assortment in T. brucei crosses: Proof that the genetic system is Mendelian and involves meiosis
    • MacLeod A., Tweedie A., McLellan S., Taylor S., Cooper A., Sweeney L., Turner C.M.R., and Tait A. Allelic segregation and independent assortment in T. brucei crosses: Proof that the genetic system is Mendelian and involves meiosis. Mol. Biochem. Parasitol. 143 (2005) 12-19
    • (2005) Mol. Biochem. Parasitol. , vol.143 , pp. 12-19
    • MacLeod, A.1    Tweedie, A.2    McLellan, S.3    Taylor, S.4    Cooper, A.5    Sweeney, L.6    Turner, C.M.R.7    Tait, A.8
  • 58
    • 0034647921 scopus 로고    scopus 로고
    • Induction of mating in Candida albicans by construction of MTLa and MTLalpha strains
    • Magee B.B., and Magee P.T. Induction of mating in Candida albicans by construction of MTLa and MTLalpha strains. Science 289 (2000) 310-313
    • (2000) Science , vol.289 , pp. 310-313
    • Magee, B.B.1    Magee, P.T.2
  • 59
    • 0014054519 scopus 로고
    • The detection of disease clustering and a generalized regression approach
    • Mantel N. The detection of disease clustering and a generalized regression approach. Cancer Res. 27 (1967) 209-222
    • (1967) Cancer Res. , vol.27 , pp. 209-222
    • Mantel, N.1
  • 60
    • 15044343109 scopus 로고    scopus 로고
    • Ploidy changes associated with disruption of two adjacent genes on Leishmania major chromosome 1
    • Martinez-Calvillo S., Stuart K., and Myler P.J. Ploidy changes associated with disruption of two adjacent genes on Leishmania major chromosome 1. Int. J. Parasitol. 35 (2005) 419-429
    • (2005) Int. J. Parasitol. , vol.35 , pp. 419-429
    • Martinez-Calvillo, S.1    Stuart, K.2    Myler, P.J.3
  • 61
    • 0027393934 scopus 로고
    • Identification, isolation, and characterization of naturally-occurring Trypanosoma cruzi variants
    • McDaniel J., and Dvorak J. Identification, isolation, and characterization of naturally-occurring Trypanosoma cruzi variants. Mol. Biochem. Parasitol. 57 (1993) 213-222
    • (1993) Mol. Biochem. Parasitol. , vol.57 , pp. 213-222
    • McDaniel, J.1    Dvorak, J.2
  • 62
    • 0032145092 scopus 로고    scopus 로고
    • The molecular karyotype of the megabase chromosomes of Trypanosoma brucei and the assignment of chromosome markers
    • Melville S.E., Leech V., Gerrard C.S., Tait A., and Blackwell J.M. The molecular karyotype of the megabase chromosomes of Trypanosoma brucei and the assignment of chromosome markers. Mol. Biochem. Parasitol. 94 (1998) 155-173
    • (1998) Mol. Biochem. Parasitol. , vol.94 , pp. 155-173
    • Melville, S.E.1    Leech, V.2    Gerrard, C.S.3    Tait, A.4    Blackwell, J.M.5
  • 63
    • 0034492653 scopus 로고    scopus 로고
    • The molecular karyotype of the megabase chromosomes of Trypanosoma brucei stock 427
    • Melville S.E., Leech V., Navarro M., and Cross G.A.M. The molecular karyotype of the megabase chromosomes of Trypanosoma brucei stock 427. Mol. Biochem. Parasitol. 111 (2000) 261-273
    • (2000) Mol. Biochem. Parasitol. , vol.111 , pp. 261-273
    • Melville, S.E.1    Leech, V.2    Navarro, M.3    Cross, G.A.M.4
  • 64
    • 0017727673 scopus 로고
    • The identification by isoenzyme patterns of two distinct strain-groups of Trypanosoma cruzi, circulating independently in a rural area of Brazil
    • Miles M., Toye P., Oswald S., and Godfrey D. The identification by isoenzyme patterns of two distinct strain-groups of Trypanosoma cruzi, circulating independently in a rural area of Brazil. Trans. R. Soc. Trop. Med. Hyg. 71 (1977) 217-225
    • (1977) Trans. R. Soc. Trop. Med. Hyg. , vol.71 , pp. 217-225
    • Miles, M.1    Toye, P.2    Oswald, S.3    Godfrey, D.4
  • 65
    • 0017854251 scopus 로고
    • Isozymic heterogeneity of Trypanosoma cruzi in the first autochthonous patients with Chagas' disease in Amazonian Brazil
    • Miles M.A., Souza A., Povoa M., Shaw J.J., Lainson R., and Toye P.J. Isozymic heterogeneity of Trypanosoma cruzi in the first autochthonous patients with Chagas' disease in Amazonian Brazil. Nature 272 (1978) 819-821
    • (1978) Nature , vol.272 , pp. 819-821
    • Miles, M.A.1    Souza, A.2    Povoa, M.3    Shaw, J.J.4    Lainson, R.5    Toye, P.J.6
  • 66
    • 0019739903 scopus 로고
    • Chagas's disease in the Amazon Basin: II. The distribution of Trypanosoma cruzi zymodemes 1 and 3 in Pará State, north Brazil
    • Miles M.A., Povoa M.M., De Souza A.A., Lainson R., Shaw J.J., and Ketteridge D.S. Chagas's disease in the Amazon Basin: II. The distribution of Trypanosoma cruzi zymodemes 1 and 3 in Pará State, north Brazil. Trans. R. Soc. Trop. Med. Hyg. 75 (1981) 667-674
    • (1981) Trans. R. Soc. Trop. Med. Hyg. , vol.75 , pp. 667-674
    • Miles, M.A.1    Povoa, M.M.2    De Souza, A.A.3    Lainson, R.4    Shaw, J.J.5    Ketteridge, D.S.6
  • 68
    • 0029830610 scopus 로고    scopus 로고
    • Gene disruptions indicate an essential function for the LmmCRK1 cdc2-related kinase of Leishmania mexicana
    • Mottram J.C., McCready B.P., Brown K.G., and Grant K.M. Gene disruptions indicate an essential function for the LmmCRK1 cdc2-related kinase of Leishmania mexicana. Mol. Microbiol. 22 (1996) 573-582
    • (1996) Mol. Microbiol. , vol.22 , pp. 573-582
    • Mottram, J.C.1    McCready, B.P.2    Brown, K.G.3    Grant, K.M.4
  • 69
    • 0026161681 scopus 로고
    • Trypanosoma cruzi: flow cytometric analysis of developmental stage differences in DNA
    • Nozaki T., and Dvorak J. Trypanosoma cruzi: flow cytometric analysis of developmental stage differences in DNA. J. Protozool. 38 (1991) 234-243
    • (1991) J. Protozool. , vol.38 , pp. 234-243
    • Nozaki, T.1    Dvorak, J.2
  • 70
    • 0027213449 scopus 로고
    • Intraspecific diversity in the response of Trypanosoma cruzi to environmental stress
    • Nozaki T., and Dvorak J. Intraspecific diversity in the response of Trypanosoma cruzi to environmental stress. J. Parasitol. 79 (1993) 451-454
    • (1993) J. Parasitol. , vol.79 , pp. 451-454
    • Nozaki, T.1    Dvorak, J.2
  • 71
    • 12744273368 scopus 로고    scopus 로고
    • Functional mapping of a trypanosome centromere by chromosome fragmentation identifies a 16-kb GC-rich transcriptional "strand-switch" domain as a major feature
    • Obado S.O., Taylor M.C., Wilkinson S.R., Bromley E.V., and Kelly J.M. Functional mapping of a trypanosome centromere by chromosome fragmentation identifies a 16-kb GC-rich transcriptional "strand-switch" domain as a major feature. Genome Res. 15 (2005) 36-43
    • (2005) Genome Res. , vol.15 , pp. 36-43
    • Obado, S.O.1    Taylor, M.C.2    Wilkinson, S.R.3    Bromley, E.V.4    Kelly, J.M.5
  • 74
    • 33644871292 scopus 로고    scopus 로고
    • Genalex 6: genetic analysis in Excel. Population genetic software for teaching and research
    • Peakall R., and Smouse P. Genalex 6: genetic analysis in Excel. Population genetic software for teaching and research. Mol. Ecol. Notes 6 (2006) 288-295
    • (2006) Mol. Ecol. Notes , vol.6 , pp. 288-295
    • Peakall, R.1    Smouse, P.2
  • 75
    • 0038512544 scopus 로고    scopus 로고
    • Evaluation of Trypanosoma cruzi hybrid stocks based on chromosomal size variation
    • Pedroso A., Cupolillo E., and Zingales B. Evaluation of Trypanosoma cruzi hybrid stocks based on chromosomal size variation. Mol. Biochem. Parasitol. 129 (2003) 79-90
    • (2003) Mol. Biochem. Parasitol. , vol.129 , pp. 79-90
    • Pedroso, A.1    Cupolillo, E.2    Zingales, B.3
  • 77
    • 12544259704 scopus 로고    scopus 로고
    • A phylogenomic inventory of meiotic genes: evidence for sex in Giardia and an early eukaryotic origin of meiosis
    • Ramesh M.A., Malik S.-B., Logsdon J., and John M. A phylogenomic inventory of meiotic genes: evidence for sex in Giardia and an early eukaryotic origin of meiosis. Curr. Biol. 15 (2005) 185-191
    • (2005) Curr. Biol. , vol.15 , pp. 185-191
    • Ramesh, M.A.1    Malik, S.-B.2    Logsdon, J.3    John, M.4
  • 78
    • 0034603698 scopus 로고    scopus 로고
    • Evolutionary relationships in Trypanosoma cruzi: molecular phylogenetics supports the existence of a new major lineage of strains
    • Robello C., Gamarro F., Castanys S., and Alvarez-Valin F. Evolutionary relationships in Trypanosoma cruzi: molecular phylogenetics supports the existence of a new major lineage of strains. Gene 246 (2000) 331-338
    • (2000) Gene , vol.246 , pp. 331-338
    • Robello, C.1    Gamarro, F.2    Castanys, S.3    Alvarez-Valin, F.4
  • 79
    • 0000379026 scopus 로고
    • Studies of polyploid Saccharomyces. I. Tetraploid segregation
    • Roman H., Phillips M.M., and Sands S.M. Studies of polyploid Saccharomyces. I. Tetraploid segregation. Genetics 40 (1955) 546-561
    • (1955) Genetics , vol.40 , pp. 546-561
    • Roman, H.1    Phillips, M.M.2    Sands, S.M.3
  • 84
    • 0020670968 scopus 로고
    • A genetic comparison between Brazilian and Bolivian zymodemes of Trypanosoma cruzi
    • Tibayrenc M., and Miles M.A. A genetic comparison between Brazilian and Bolivian zymodemes of Trypanosoma cruzi. Trans. R. Soc. Trop. Med. Hyg. 77 (1983) 76-83
    • (1983) Trans. R. Soc. Trop. Med. Hyg. , vol.77 , pp. 76-83
    • Tibayrenc, M.1    Miles, M.A.2
  • 85
    • 0342636508 scopus 로고
    • Natural populations of Trypanosoma cruzi, the agent of Chagas disease, have a complex multiclonal structure
    • Tibayrenc M., Ward P., Moya A., and Ayala F.J. Natural populations of Trypanosoma cruzi, the agent of Chagas disease, have a complex multiclonal structure. Proc. Natl. Acad. Sci. USA 83 (1986) 115-119
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 115-119
    • Tibayrenc, M.1    Ward, P.2    Moya, A.3    Ayala, F.J.4
  • 86
    • 0000595112 scopus 로고
    • Isozyme variability of Trypanosoma cruzi, the agent of Chagas' disease: genetical, taxonomical and epidemiological significance
    • Tibayrenc M., and Ayala F. Isozyme variability of Trypanosoma cruzi, the agent of Chagas' disease: genetical, taxonomical and epidemiological significance. Evolution 42 (1988) 277-292
    • (1988) Evolution , vol.42 , pp. 277-292
    • Tibayrenc, M.1    Ayala, F.2
  • 87
    • 0027497964 scopus 로고
    • Genetic characterization of six parasitic protozoa: parity between random-primer DNA typing and multilocus enzyme electrophoresis
    • Tibayrenc M., Neubauer K., Barnabé C., Guerrini F., Skarecky D., and Ayala F.J. Genetic characterization of six parasitic protozoa: parity between random-primer DNA typing and multilocus enzyme electrophoresis. Proc. Natl. Acad. Sci. USA 90 (1993) 1335-1339
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1335-1339
    • Tibayrenc, M.1    Neubauer, K.2    Barnabé, C.3    Guerrini, F.4    Skarecky, D.5    Ayala, F.J.6
  • 88
    • 0033367221 scopus 로고    scopus 로고
    • Toward an integrated genetic epidemiology of parasitic protozoa and other pathogens
    • Tibayrenc M. Toward an integrated genetic epidemiology of parasitic protozoa and other pathogens. Annu. Rev. Genet. 33 (1999) 449-477
    • (1999) Annu. Rev. Genet. , vol.33 , pp. 449-477
    • Tibayrenc, M.1
  • 89
    • 0036746010 scopus 로고    scopus 로고
    • The clonal theory of parasitic protozoa: 12 years on
    • Tibayrenc M., and Ayala F.J. The clonal theory of parasitic protozoa: 12 years on. Trends Parasitol. 18 (2002) 405-410
    • (2002) Trends Parasitol. , vol.18 , pp. 405-410
    • Tibayrenc, M.1    Ayala, F.J.2
  • 90
    • 0037757540 scopus 로고    scopus 로고
    • Trypanothione synthetase locus in Trypanosoma cruzi CL Brener strain shows an extensive allelic divergence
    • Tran A.N., Andersson B., Pettersson U., and Åslund L. Trypanothione synthetase locus in Trypanosoma cruzi CL Brener strain shows an extensive allelic divergence. Acta Trop. 87 (2003) 269-278
    • (2003) Acta Trop. , vol.87 , pp. 269-278
    • Tran, A.N.1    Andersson, B.2    Pettersson, U.3    Åslund, L.4
  • 91
    • 0025642730 scopus 로고
    • Evidence that the mechanism of gene exchange in Trypanosoma brucei involves meiosis and syngamy
    • Turner C., Sternberg J., Buchanan N., Smith E., Hide G., and Tait A. Evidence that the mechanism of gene exchange in Trypanosoma brucei involves meiosis and syngamy. Parasitology 101 (1990) 377-386
    • (1990) Parasitology , vol.101 , pp. 377-386
    • Turner, C.1    Sternberg, J.2    Buchanan, N.3    Smith, E.4    Hide, G.5    Tait, A.6
  • 93
    • 6944246593 scopus 로고    scopus 로고
    • Chromosomal polymorphism, gene synteny and genome size in T. cruzi I and T. cruzi II groups
    • Vargas N., Pedroso A., and Zingales B. Chromosomal polymorphism, gene synteny and genome size in T. cruzi I and T. cruzi II groups. Mol. Biochem. Parasitol. 138 (2004) 131-141
    • (2004) Mol. Biochem. Parasitol. , vol.138 , pp. 131-141
    • Vargas, N.1    Pedroso, A.2    Zingales, B.3
  • 94
    • 0029143811 scopus 로고
    • Plasticity of gp63 gene organization in Leishmania (Viannia) braziliensis and Leishmania (Viannia) peruviana
    • Victoir K., Dujardin J., de Doncker S., Barker D., Arevalo J., Hamers R., and Le Ray D. Plasticity of gp63 gene organization in Leishmania (Viannia) braziliensis and Leishmania (Viannia) peruviana. Parasitology 111 (1995) 265-273
    • (1995) Parasitology , vol.111 , pp. 265-273
    • Victoir, K.1    Dujardin, J.2    de Doncker, S.3    Barker, D.4    Arevalo, J.5    Hamers, R.6    Le Ray, D.7
  • 95
    • 33846588843 scopus 로고    scopus 로고
    • Trypanosoma cruzi: typing of genotype (sub)lineages in megacolon samples from Bolivian patients
    • Virreira M., Serrano G., Maldonado L., and Svoboda M. Trypanosoma cruzi: typing of genotype (sub)lineages in megacolon samples from Bolivian patients. Acta Trop. 100 (2006) 252-255
    • (2006) Acta Trop. , vol.100 , pp. 252-255
    • Virreira, M.1    Serrano, G.2    Maldonado, L.3    Svoboda, M.4
  • 96
    • 0023263402 scopus 로고
    • DNA contents and molecular karyotypes of hybrid Trypanosoma brucei
    • Wells J.M., Prospero T., Jenni L., and Le Page R. DNA contents and molecular karyotypes of hybrid Trypanosoma brucei. Mol. Biochem. Parasitol. 24 (1987) 103-116
    • (1987) Mol. Biochem. Parasitol. , vol.24 , pp. 103-116
    • Wells, J.M.1    Prospero, T.2    Jenni, L.3    Le Page, R.4
  • 97
    • 31544467265 scopus 로고    scopus 로고
    • Two hybridization events define the population structure of Trypanosoma cruzi
    • Westenberger S.J., Barnabé C., Campbell D.A., and Sturm N.R. Two hybridization events define the population structure of Trypanosoma cruzi. Genetics 171 (2005) 527-543
    • (2005) Genetics , vol.171 , pp. 527-543
    • Westenberger, S.J.1    Barnabé, C.2    Campbell, D.A.3    Sturm, N.R.4
  • 99
    • 0023099368 scopus 로고
    • Temperature modulation of growth rates and glucosephosphate isomerase isozyme activity in Trypanosoma cruzi
    • Widmer G., Dvorak J., and Miles M. Temperature modulation of growth rates and glucosephosphate isomerase isozyme activity in Trypanosoma cruzi. Mol. Biochem. Parasitol. 23 (1987) 55-62
    • (1987) Mol. Biochem. Parasitol. , vol.23 , pp. 55-62
    • Widmer, G.1    Dvorak, J.2    Miles, M.3
  • 101
    • 33845791934 scopus 로고    scopus 로고
    • Resolution of multiclonal infections of Trypanosoma cruzi from naturally infected triatomine bugs and from experimentally infected mice by direct plating on a sensitive solid medium
    • Yeo M., Lewis M.D., Carrasco H.J., Acosta N., Llewellyn M., da Silva Valente S.A., de Costa Valente V., de Arias A.R., and Miles M.A. Resolution of multiclonal infections of Trypanosoma cruzi from naturally infected triatomine bugs and from experimentally infected mice by direct plating on a sensitive solid medium. Int. J. Parasitol. 37 (2007) 111-120
    • (2007) Int. J. Parasitol. , vol.37 , pp. 111-120
    • Yeo, M.1    Lewis, M.D.2    Carrasco, H.J.3    Acosta, N.4    Llewellyn, M.5    da Silva Valente, S.A.6    de Costa Valente, V.7    de Arias, A.R.8    Miles, M.A.9


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