Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination

Journal of Controlled Release

Volumn 138, Issue 2, 2009, Pages 113-121

  Slütter, Bram ^a   Plapied, Laurence ^b   Fievez, Virgine ^b   Alonso Sande, Maria ^c   des Rieux, Anne ^b   Schneider, Yves Jacques ^b   Van Riet, Elly ^a   Jiskoot, Wim ^a   Préat, Véronique ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Chitosan; M cells; Nanoparticles; Oral vaccine; Trimethyl chitosan

Indexed keywords

ANTIBODY RESPONSE; BIODEGRADABLE NANOPARTICLE; CACO-2 CELLS; CONFOCAL LASER SCANNING MICROSCOPY; DENDRITIC CELLS; EX-VIVO; HUMAN MONOCYTES; IMMUNE RESPONSE; IN-VITRO; INTESTINAL EPITHELIUM; M-CELLS; MECHANISTIC STUDIES; ORAL ADMINISTRATION; ORAL VACCINE; OVALBUMIN; PLGA NANOPARTICLES; TRIMETHYL-CHITOSAN; TRIPOLYPHOSPHATE;

ANTIBODIES; ANTIGENS; CELL MEMBRANES; CHITIN; CHITOSAN; COAGULATION; CONFOCAL MICROSCOPY; DENDRIMERS; FLOW CYTOMETRY; GELATION; VACCINES;

NANOPARTICLES;

CHITOSAN; FLUORESCEIN ISOTHIOCYANATE; N TRIMETHYLCHITOSAN; NANOPARTICLE; OVALBUMIN; POLYGLACTIN; TRIPOLYPHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BIODEGRADABILITY; CELL MATURATION; CELL STRAIN CACO 2; CHEMICAL COMPOSITION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DENDRITIC CELL; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; GELATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IN VITRO STUDY; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BIOCOMPATIBLE MATERIALS; CACO-2 CELLS; CELL SURVIVAL; CHITOSAN; DENDRITIC CELLS; DRUG CARRIERS; DRUG COMPOUNDING; DUODENUM; FEMALE; HUMANS; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; MICE; MICE, INBRED BALB C; NANOPARTICLES; PARTICLE SIZE; PEYER'S PATCHES; SERUM ALBUMIN, BOVINE; SURFACE PROPERTIES; VACCINES;

EID: 67651230400     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.05.011     Document Type: Article

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