메뉴 건너뛰기




Volumn 78, Issue 1, 2005, Pages 62-69

Local and systemic activity of the polysaccharide chitosan at lymphoid tissues after oral administration

Author keywords

Cytokines; Immature dendritic cell; Mucosa

Indexed keywords

ANTIGEN; B7 ANTIGEN; CD11B ANTIGEN; CD3 ANTIGEN; CD86 ANTIGEN; CHITIN; CHITOSAN; CYTOKINE; GLYCOPROTEIN P 15095; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; POLYSACCHARIDE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 22144431850     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0904541     Document Type: Article
Times cited : (116)

References (55)
  • 1
    • 0037983745 scopus 로고    scopus 로고
    • Mucosal immunity
    • Mayer, L. (2003) Mucosal immunity. Pediatrics 111, 1595-1600.
    • (2003) Pediatrics , vol.111 , pp. 1595-1600
    • Mayer, L.1
  • 2
    • 0033792233 scopus 로고    scopus 로고
    • Oral tolerance, an active immunologic process mediated by multiple mechanisms
    • Weiner, H. L. (2000) Oral tolerance, an active immunologic process mediated by multiple mechanisms. J. Clin. Invest. 106, 935-937.
    • (2000) J. Clin. Invest. , vol.106 , pp. 935-937
    • Weiner, H.L.1
  • 3
    • 0036278333 scopus 로고    scopus 로고
    • T-cell activation occurs simultaneously in local and peripheral lyniphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen, although tolerized T cells display a defect in cell division
    • Smith, K. M., Davidson, J. M., Garside, P. (2002) T-cell activation occurs simultaneously in local and peripheral lyniphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen, although tolerized T cells display a defect in cell division. Immunology 106, 144-158.
    • (2002) Immunology , vol.106 , pp. 144-158
    • Smith, K.M.1    Davidson, J.M.2    Garside, P.3
  • 4
    • 2942620546 scopus 로고    scopus 로고
    • Therapeutic potential of oral tolerance
    • Mayer, L., Shao, L. (2004) Therapeutic potential of oral tolerance. Nat. Rev. Immunol. 4, 407-419.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 407-419
    • Mayer, L.1    Shao, L.2
  • 6
    • 0038325751 scopus 로고    scopus 로고
    • Mucosal immunization and adjuvants: A brief overview of recent advances and challenges
    • Holmgren, J., Czerkinsky, C., Eriksson, K., Mharandi, A. (2003) Mucosal immunization and adjuvants: a brief overview of recent advances and challenges. Vaccine 21 (Suppl. 2), S89-S95.
    • (2003) Vaccine , vol.21 , Issue.SUPPL. 2
    • Holmgren, J.1    Czerkinsky, C.2    Eriksson, K.3    Mharandi, A.4
  • 7
    • 85044700671 scopus 로고    scopus 로고
    • Recent advances in vaccine adjuvants for systemic and mucosal administration
    • O'Hagan, D. T. (1998) Recent advances in vaccine adjuvants for systemic and mucosal administration. J. Pharm. Pharmacol. 50, 1-10.
    • (1998) J. Pharm. Pharmacol. , vol.50 , pp. 1-10
    • O'Hagan, D.T.1
  • 8
    • 0034214322 scopus 로고    scopus 로고
    • Effective mucosal immunization against respiratory syncytial virus using purified F protein and a genetically detoxified cholera holotoxin, CT-E29H
    • Tebbey, P. W., Scheuer, C. A., Peek, J. A., Zhu, D., LaPierre, N. A., Green, B. A., Phillips, E. D., Ibraghimov, A. R., Eldridge, J. H., Hancock, G. E. (2000) Effective mucosal immunization against respiratory syncytial virus using purified F protein and a genetically detoxified cholera holotoxin, CT-E29H. Vaccine 18, 2723-2734.
    • (2000) Vaccine , vol.18 , pp. 2723-2734
    • Tebbey, P.W.1    Scheuer, C.A.2    Peek, J.A.3    Zhu, D.4    Lapierre, N.A.5    Green, B.A.6    Phillips, E.D.7    Ibraghimov, A.R.8    Eldridge, J.H.9    Hancock, G.E.10
  • 9
    • 0034327167 scopus 로고    scopus 로고
    • Cutting edge: The mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues
    • van Ginkel, F. W., Jackson, R. J., Yuki, Y., McGhee, J. R. (2000) Cutting edge: the mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues. J. Immunol. 165, 4778-4782.
    • (2000) J. Immunol. , vol.165 , pp. 4778-4782
    • Van Ginkel, F.W.1    Jackson, R.J.2    Yuki, Y.3    McGhee, J.R.4
  • 13
    • 4043093490 scopus 로고    scopus 로고
    • Reduction of nasal colonization of nontypeable Haemophilus influenzae following intranasal immunization with rLP4/rLP6/UspA2 proteins combined with aqueous formulation of RC529
    • Mason, K. W., Zhu, D., Scheuer, C. A., McMichael, J. C., Zlotnick, G. W., Green, B. A. (2004) Reduction of nasal colonization of nontypeable Haemophilus influenzae following intranasal immunization with rLP4/rLP6/UspA2 proteins combined with aqueous formulation of RC529. Vaccine 22, 3449-3456.
    • (2004) Vaccine , vol.22 , pp. 3449-3456
    • Mason, K.W.1    Zhu, D.2    Scheuer, C.A.3    McMichael, J.C.4    Zlotnick, G.W.5    Green, B.A.6
  • 14
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • Illum, L. (1998) Chitosan and its use as a pharmaceutical excipient. Pharm. Res. 15, 1326-1331.
    • (1998) Pharm. Res. , vol.15 , pp. 1326-1331
    • Illum, L.1
  • 15
    • 0037304911 scopus 로고    scopus 로고
    • Protective levels of diphtheria-neutralizing antibody induced in healthy volunteers by unilateral priming-boosting intranasal immunization associated with restricted ipsilateral mucosal secretory immunoglobulin A
    • Mills, K. H., Cosgrove, C., McNeela, E. A., Sexton, A., Giemza, R., Jabbal-Gill, I., Church, A., Lin, W., Illum, L., Podda, A., Rappuoli, R., Pizza, M., Griffin, G. E., Lewis, D. J. (2003) Protective levels of diphtheria-neutralizing antibody induced in healthy volunteers by unilateral priming-boosting intranasal immunization associated with restricted ipsilateral mucosal secretory immunoglobulin A. Infect. Immun. 71, 726-732.
    • (2003) Infect. Immun. , vol.71 , pp. 726-732
    • Mills, K.H.1    Cosgrove, C.2    McNeela, E.A.3    Sexton, A.4    Giemza, R.5    Jabbal-Gill, I.6    Church, A.7    Lin, W.8    Illum, L.9    Podda, A.10    Rappuoli, R.11    Pizza, M.12    Griffin, G.E.13    Lewis, D.J.14
  • 16
    • 0006752021 scopus 로고
    • Hypocholesterolemic action of chitosans with different viscosity in rats
    • Sugano, M., Watanabe, S., Kishi, A., Izume, M., Ohtakara, A. (1988) Hypocholesterolemic action of chitosans with different viscosity in rats. Lipids 23, 187-191.
    • (1988) Lipids , vol.23 , pp. 187-191
    • Sugano, M.1    Watanabe, S.2    Kishi, A.3    Izume, M.4    Ohtakara, A.5
  • 17
    • 8244242523 scopus 로고    scopus 로고
    • Dietary fibers modulate indices of intestinal immune function in rats
    • Lim, B. O., Yamada, K., Nonaka, M., Kuramoto, Y., Hung, P., Sugano, M. (1997) Dietary fibers modulate indices of intestinal immune function in rats. J. Nutr. 127, 663-667.
    • (1997) J. Nutr. , vol.127 , pp. 663-667
    • Lim, B.O.1    Yamada, K.2    Nonaka, M.3    Kuramoto, Y.4    Hung, P.5    Sugano, M.6
  • 19
    • 0035813752 scopus 로고    scopus 로고
    • Oral drug absorption enhancement by chitosan and its derivatives
    • Thanou, M., Verhorf, J. C., Junginger, H. E. (2001) Oral drug absorption enhancement by chitosan and its derivatives. Adv. Drug Deliv. Rev. 52, 117-126.
    • (2001) Adv. Drug Deliv. Rev. , vol.52 , pp. 117-126
    • Thanou, M.1    Verhorf, J.C.2    Junginger, H.E.3
  • 22
    • 0037471396 scopus 로고    scopus 로고
    • Chitosan microparticles for mucosal vaccination against diphtheria: Oral and nasal efficacy studies in mice
    • van der Lubben, I. M., Kersten, G., Fretz, M. M., Beuvery, C., Coos Verhoef, J., Junginger, H. E. (2003) Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice. Vaccine 21, 1400-1408.
    • (2003) Vaccine , vol.21 , pp. 1400-1408
    • Van Der Lubben, I.M.1    Kersten, G.2    Fretz, M.M.3    Beuvery, C.4    Coos Verhoef, J.5    Junginger, H.E.6
  • 23
    • 0032374351 scopus 로고    scopus 로고
    • Stimulation of mucosal and systemic antibody responses against Bordetella pertussis filamentous haemagglutinin and recombinant pertussis toxin after nasal administration with chitosan in mice
    • Jabbal-Gill, I., Fisher, A. N., Rappuoli, R., Davis, S. S., Illum, L. (1998) Stimulation of mucosal and systemic antibody responses against Bordetella pertussis filamentous haemagglutinin and recombinant pertussis toxin after nasal administration with chitosan in mice. Vaccine 16, 2039-2046.
    • (1998) Vaccine , vol.16 , pp. 2039-2046
    • Jabbal-Gill, I.1    Fisher, A.N.2    Rappuoli, R.3    Davis, S.S.4    Illum, L.5
  • 24
    • 1542359555 scopus 로고    scopus 로고
    • Early events associated to the oral co-administration of type II collagen and chitosan: Induction of anti-inflammatory cytokines
    • Porporatto, C., Bianco, I. D., Cabanillas, A. M., Correa, S. G. (2004) Early events associated to the oral co-administration of type II collagen and chitosan: induction of anti-inflammatory cytokines. Int. Immunol. 16, 433-441.
    • (2004) Int. Immunol. , vol.16 , pp. 433-441
    • Porporatto, C.1    Bianco, I.D.2    Cabanillas, A.M.3    Correa, S.G.4
  • 25
    • 9544222615 scopus 로고    scopus 로고
    • Adjuvant synergy: The effects of nasal coadministration of adjuvants
    • Moschos, S., Bramwell, V., Somavarapu, S., Alpar, H. (2004) Adjuvant synergy: the effects of nasal coadministration of adjuvants. Immunol. Cell Biol. 82, 628-637.
    • (2004) Immunol. Cell Biol. , vol.82 , pp. 628-637
    • Moschos, S.1    Bramwell, V.2    Somavarapu, S.3    Alpar, H.4
  • 27
    • 0344088434 scopus 로고    scopus 로고
    • Chitosan induces different L-arginine metabolic pathways in resting and inflammatory macrophages
    • Porporatto, C., Bianco, I. D., Riera, C. M., Correa, S. G. (2003) Chitosan induces different L-arginine metabolic pathways in resting and inflammatory macrophages. Biochem. Biophys. Res. Commun. 304, 266-272.
    • (2003) Biochem. Biophys. Res. Commun. , vol.304 , pp. 266-272
    • Porporatto, C.1    Bianco, I.D.2    Riera, C.M.3    Correa, S.G.4
  • 28
    • 0033956192 scopus 로고    scopus 로고
    • Chitosan-induced phospholipase A2 activation and arachidonic acid mobilization in P388D1 macrophages
    • Bianco, I. D., Balsinde, J., Beltramo, D. M., Castagna, L. F., Landa, C. A., Dennis, E. A. (2000) Chitosan-induced phospholipase A2 activation and arachidonic acid mobilization in P388D1 macrophages. FEBS Lett. 466, 292-294.
    • (2000) FEBS Lett. , vol.466 , pp. 292-294
    • Bianco, I.D.1    Balsinde, J.2    Beltramo, D.M.3    Castagna, L.F.4    Landa, C.A.5    Dennis, E.A.6
  • 29
    • 32744460072 scopus 로고    scopus 로고
    • Characterization of murine macrophages
    • (J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, W. Strober, eds.), New York, NY, Wiley & Sons, 14.2.8
    • Riedy, M. C. (1997) Characterization of murine macrophages. In Current Protocols in Immunology (J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, W. Strober, eds.), New York, NY, Wiley & Sons, 14.2.8.
    • (1997) Current Protocols in Immunology
    • Riedy, M.C.1
  • 30
    • 0010623062 scopus 로고
    • Methodology and quality control for flow cytometry
    • (N. R. Rose, E. C. De Macario, J-L. Fahey, H. Friedman, G. M. Penn, eds.), Washington, DC, American Society for Microbiology
    • Lewis, D. E., Rickman, W. J. (1992) Methodology and quality control for flow cytometry. In Manual of Clinical Laboratory Immunology (N. R. Rose, E. C. De Macario, J-L. Fahey, H. Friedman, G. M. Penn, eds.), Washington, DC, American Society for Microbiology, 164.
    • (1992) Manual of Clinical Laboratory Immunology , pp. 164
    • Lewis, D.E.1    Rickman, W.J.2
  • 31
    • 0031127940 scopus 로고    scopus 로고
    • Involvement of peritoneal dendritic cells in the induction of autoimmune prostatitis
    • Correa, S. G., Riera, C. M., Iribarren, P. (1997) Involvement of peritoneal dendritic cells in the induction of autoimmune prostatitis. J. Autoimmun. 10, 107-113.
    • (1997) J. Autoimmun. , vol.10 , pp. 107-113
    • Correa, S.G.1    Riera, C.M.2    Iribarren, P.3
  • 32
    • 0032100767 scopus 로고    scopus 로고
    • Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen
    • Gutgemann, I., Fahrer, A. M., Altman, J. D., Davis, M. M., Chien, Y. (1998) Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen. Immunity 8, 667-673.
    • (1998) Immunity , vol.8 , pp. 667-673
    • Gutgemann, I.1    Fahrer, A.M.2    Altman, J.D.3    Davis, M.M.4    Chien, Y.5
  • 33
    • 0033563273 scopus 로고    scopus 로고
    • Antigen-specific T cell activation and proliferation during oral tolerance induction
    • Sun, J., Dirden-Kramer, B., Ito, K., Ernst, P. B., van Houten, N. (1999) Antigen-specific T cell activation and proliferation during oral tolerance induction. J. Immunol. 162, 5868-5875.
    • (1999) J. Immunol. , vol.162 , pp. 5868-5875
    • Sun, J.1    Dirden-Kramer, B.2    Ito, K.3    Ernst, P.B.4    Van Houten, N.5
  • 36
    • 0034699514 scopus 로고    scopus 로고
    • Flow cytometric measurement of intracellular cytokines
    • Pala, P., Hussell, T., Openshaw, P. J. (2000) Flow cytometric measurement of intracellular cytokines. J. Immunol. Methods 243, 107-124.
    • (2000) J. Immunol. Methods , vol.243 , pp. 107-124
    • Pala, P.1    Hussell, T.2    Openshaw, P.J.3
  • 39
    • 0028220472 scopus 로고
    • Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gancher disease
    • Hollak, C. E., van Weely, S., van Oers, M. H., Aerts, J. M. (1994) Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gancher disease. J. Clin. Invest. 93, 1288-1292.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1288-1292
    • Hollak, C.E.1    Van Weely, S.2    Van Oers, M.H.3    Aerts, J.M.4
  • 40
    • 0031008078 scopus 로고    scopus 로고
    • Maturation of Peyer's patch dendritic cells in vitro upon stimulation via cytokines or CD40 triggering
    • Ruedl, C., Hubele, S. (1997) Maturation of Peyer's patch dendritic cells in vitro upon stimulation via cytokines or CD40 triggering. Eur. J. Immunol. 27, 1325-1330.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1325-1330
    • Ruedl, C.1    Hubele, S.2
  • 41
    • 0035871705 scopus 로고    scopus 로고
    • Unique functions of CD11b+, CD8α+, and double-negative Peyer's patch dendritic cells
    • Iwasaki, A., Kelsall, B. L. (2001) Unique functions of CD11b+, CD8α+, and double-negative Peyer's patch dendritic cells. J. Immunol. 166, 4884-4890.
    • (2001) J. Immunol. , vol.166 , pp. 4884-4890
    • Iwasaki, A.1    Kelsall, B.L.2
  • 42
    • 1542343951 scopus 로고    scopus 로고
    • In situ demonstration of dendritic cell migration from rat intestine to mesenteric lymph nodes: Relationships to maturation and role of chemokines
    • Kobayashi, H., Miura, S., Nagata, H., Tsuzuki, Y., Hokari, R., Ogino, T., Watanabe, C., Azuma, T., Ishii, H. (2004) In situ demonstration of dendritic cell migration from rat intestine to mesenteric lymph nodes: relationships to maturation and role of chemokines. J. Leukoc. Biol. 75, 434-442.
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 434-442
    • Kobayashi, H.1    Miura, S.2    Nagata, H.3    Tsuzuki, Y.4    Hokari, R.5    Ogino, T.6    Watanabe, C.7    Azuma, T.8    Ishii, H.9
  • 43
    • 0026603367 scopus 로고
    • The MRC OX-62 antigen: A useful marker in the purification of rat veiled cells with the biochemical properties of an integrin
    • Brenan, M., Puklavec, M. (1992) The MRC OX-62 antigen: a useful marker in the purification of rat veiled cells with the biochemical properties of an integrin. J. Exp. Med. 175, 1457-1465.
    • (1992) J. Exp. Med. , vol.175 , pp. 1457-1465
    • Brenan, M.1    Puklavec, M.2
  • 44
    • 0141853945 scopus 로고    scopus 로고
    • Phenotype and function of rat dendritic cell subsets
    • Yrlid, U., MacPherson, G. (2003) Phenotype and function of rat dendritic cell subsets. APMIS 111, 756-765.
    • (2003) APMIS , vol.111 , pp. 756-765
    • Yrlid, U.1    MacPherson, G.2
  • 45
    • 0035174046 scopus 로고    scopus 로고
    • Collaboration of epithelial cells with organized mucosal lymphoid tissues
    • Neutra, M. R., Mantis, N. J., Krachenbuhl, J. P. (2001) Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nat. Immunol. 2, 1004-1009.
    • (2001) Nat. Immunol. , vol.2 , pp. 1004-1009
    • Neutra, M.R.1    Mantis, N.J.2    Krachenbuhl, J.P.3
  • 46
    • 0033584234 scopus 로고    scopus 로고
    • Freshly isolated Peyer's patches, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells
    • Iwasaki, A., Kelsall, B. L. (1999) Freshly isolated Peyer's patches, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J. Exp. Med. 190, 229-239.
    • (1999) J. Exp. Med. , vol.190 , pp. 229-239
    • Iwasaki, A.1    Kelsall, B.L.2
  • 47
    • 0034885046 scopus 로고    scopus 로고
    • The mucosal milieu creates tolerogenic dendritic cells and Tr1 and Th3 regulatory cells
    • Weiner, H. (2001) The mucosal milieu creates tolerogenic dendritic cells and Tr1 and Th3 regulatory cells. Nat. Immunol. 2, 671-672.
    • (2001) Nat. Immunol. , vol.2 , pp. 671-672
    • Weiner, H.1
  • 48
    • 0026607155 scopus 로고
    • IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function
    • Ding, L., Shevach, E. M. (1992) IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function. J. Immunol. 148, 3133-3139.
    • (1992) J. Immunol. , vol.148 , pp. 3133-3139
    • Ding, L.1    Shevach, E.M.2
  • 49
    • 0036134861 scopus 로고    scopus 로고
    • Detection of early changes in autoimmune T cell phenotype and function following intravenous administration of type II collagen in a TCR-transgenic model
    • Brand, D. D., Myers, L. K., Whittington, K. B., Lathman, K. A., Stuart, J. M., Kang, A. H., Rosloniec, E. F. (2002) Detection of early changes in autoimmune T cell phenotype and function following intravenous administration of type II collagen in a TCR-transgenic model. J. Immunol. 168, 490-498.
    • (2002) J. Immunol. , vol.168 , pp. 490-498
    • Brand, D.D.1    Myers, L.K.2    Whittington, K.B.3    Lathman, K.A.4    Stuart, J.M.5    Kang, A.H.6    Rosloniec, E.F.7
  • 51
    • 0028200604 scopus 로고
    • Molecular adjuvants and immunomodulators: New approaches to immunization
    • Johnson, A. G. (1994) Molecular adjuvants and immunomodulators: new approaches to immunization. Clin. Microbiol. Rev. 7, 277-289.
    • (1994) Clin. Microbiol. Rev. , vol.7 , pp. 277-289
    • Johnson, A.G.1
  • 52
    • 0036912057 scopus 로고    scopus 로고
    • Kinetics and mode of peptide delivery via the respiratory mucosa determine the outcome of activation versus Th2 immunity in allergic inflammation of the airways
    • Hall, G., Lund, L., Lamb, J. R., Jarman, E. R. (2002) Kinetics and mode of peptide delivery via the respiratory mucosa determine the outcome of activation versus Th2 immunity in allergic inflammation of the airways. J. Allergy Clin. Immunol. 110, 883-890.
    • (2002) J. Allergy Clin. Immunol. , vol.110 , pp. 883-890
    • Hall, G.1    Lund, L.2    Lamb, J.R.3    Jarman, E.R.4
  • 53
    • 1842583687 scopus 로고    scopus 로고
    • Receptor-mediated stimulatory effect of oligochitosan in macrophages
    • Feng, J., Zhao, L., Yu, Q. (2004) Receptor-mediated stimulatory effect of oligochitosan in macrophages. Biochem. Biophys. Res. Commun. 317, 414-420.
    • (2004) Biochem. Biophys. Res. Commun. , vol.317 , pp. 414-420
    • Feng, J.1    Zhao, L.2    Yu, Q.3
  • 54
    • 0034728779 scopus 로고    scopus 로고
    • Chitinous materials inhibit nitric oxide production by activated RAW 264.7 macrophages
    • Hwang, S. M., Chen, C. Y., Chen, S. S., Chen, J. C. (2000) Chitinous materials inhibit nitric oxide production by activated RAW 264.7 macrophages. Biochem. Biophys. Res. Commun. 271, 229-233.
    • (2000) Biochem. Biophys. Res. Commun. , vol.271 , pp. 229-233
    • Hwang, S.M.1    Chen, C.Y.2    Chen, S.S.3    Chen, J.C.4
  • 55
    • 0043095370 scopus 로고    scopus 로고
    • Chitosan inhibits prostaglandin E2 formation and cyclooxygenase-2 induction in lipopolysacharide-treated RAW 264.7 macrophages
    • Chou, T. C., Fu, E., Shen, E. C. (2003) Chitosan inhibits prostaglandin E2 formation and cyclooxygenase-2 induction in lipopolysacharide-treated RAW 264.7 macrophages. Biochem. Biophys. Res. Commun. 308, 403-407.
    • (2003) Biochem. Biophys. Res. Commun. , vol.308 , pp. 403-407
    • Chou, T.C.1    Fu, E.2    Shen, E.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.