Endogenous cGMP regulates adult longevity via the insulin signaling pathway in Caenorhabditis elegans

Aging Cell

Volumn 8, Issue 4, 2009, Pages 473-483

  Hahm, Jeong Hoon ^a   Kim, Sunhee ^a   Paik, Young Ki ^a  

^a Yonsei University   (South Korea)

Author keywords

C. elegans; cGMP; GPA 3; Insulin IGF 1 Pathway; Lifespan; Phosphodiesterase

Indexed keywords

CYCLIC GMP; CYCLIC GMP PHOSPHODIESTERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HELMINTH PROTEIN; INSULIN; MESSENGER RNA; PHOSPHODIESTERASE I; PHOSPHODIESTERASE V; PROTEIN DAF 28; PROTEIN GPA 3; PROTEIN INS 7; SOMATOMEDIN C; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CELL LEVEL; CELLULAR STRESS RESPONSE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION REGULATION; INSULIN RELEASE; LIFE EXTENSION; LONGEVITY; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CYCLIC GMP; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; INSULIN; LONGEVITY; OXIDATIVE STRESS; PEPTIDE HORMONES; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

CAENORHABDITIS ELEGANS;

EID: 67651172980     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2009.00495.x     Document Type: Article

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