Molecular time-course and the metabolic basis of entry into Dauer in Caenorhabditis elegans

PLoS ONE

Volumn 4, Issue 1, 2009, Pages

  Jeong, Pan Young ^a,b   Kwon, Min Seok ^a   Joo, Hyoe Jin ^a   Paik, Young Ki ^a  

^a Yonsei University   (South Korea)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; FAT; GLYOXYLIC ACID; PHEROMONE; CAENORHABDITIS ELEGANS PROTEIN; DAUMONE, C ELEGANS; FATTY ACID;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; CULTURE MEDIUM; DEVELOPMENTAL STAGE; DNA MICROARRAY; ENERGY BALANCE; ENERGY EXPENDITURE; GENE CONTROL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE PROBE; GENETIC DATABASE; LARVAL DEVELOPMENT; LIPID METABOLISM; METABOLIC REGULATION; NONHUMAN; SIGNAL TRANSDUCTION; SURVIVAL; TIME SERIES ANALYSIS; ANIMAL; COMPARATIVE STUDY; GENE; GENETICS; METABOLISM;

CAENORHABDITIS ELEGANS; NEMATODA;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DATABASES, GENETIC; FATTY ACIDS; GENE EXPRESSION PROFILING; GENES, HELMINTH; PHEROMONES; SIGNAL TRANSDUCTION;

EID: 58349085789     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004162     Document Type: Article

References (51)

1. Riddle DL, Albert PS (1997) Genetic and environmental regulation of dauer larva development: C. elegans II. New York: Cold Spring Harvor Laboratory Press. pp 739-768.
2. Golden JW, Riddle DL (1982) A pheromone influences larval development in the nematode Caenorhabditis elegans. Science 218: 578-80.
3. Jeong PY, Jung M, Yim YH, Kim H, Park M, et al. (2005) Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone. Nature 433: 541-545.
4. Riddle DL, Swanson MM, Albert PS (1981) Interacting genes in nematode dauer larva formation. Nature 290: 668-671.
5. Butcher RA, Fujita M, Schroeder FC, Clardy J (2007) Small-molecule pheromones that control dauer development in Caenorhabditis elegans. Nat Chem Biol 7: 420-222.
6. Cassada RC, Russell RL (1975) The dauer larva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans. Dev Biol 46: 326-342.
7. Klass M, Hirsh D (1976) Non-ageing developmental variant of Caenorhabditis elegans. Nature 260: 523-525.
8. Kim S, Paik YK (2008) Developmental and reproductive consequences of prolonged non-aging dauer in Caenorhabditis elegans. Biochem Biophys Res Commun 368: 588-92.
9. Bargmann CI, Horvitz HR (1991) Control of larval development by chemosensory neurons in Caenorhabditis elegans. Science 251: 1243-1246.
10. Zwaal RR, Mendel JE, Sternberg PW, Plasterk RH (1997) Two neuronal G proteins are involved in chemosensation of the Caenorhabditis elegans Dauer-inducing pheromone. Genetics 145: 715-27.
11. Baiga TJ, Guo H, Xing Y, O'Doherty GA, Dillin A, et al. (2008) Metabolite Induction of Caenorhabditis elegans Dauer Larvae Arises via Transport in the Pharynx. ACS Chem Biol. E-publication.
12. Liu T, Zimmerman KK, Patterson GI (2004) Regulation of signaling genes by TGF-beta during entry into dauer diapause in C. elegans. BMC Dev Biol 4: 11.
13. McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D (2004) Shared transcriptional signature in Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. J Biol Chem 279: 44533-44543.
14. Wang J, Kim SK (2003) Global analysis of dauer gene expression in Caenorhabditis elegans. Development 130: 1621-1634.
15. Holt SJ, Riddle DL (2003) SAGE surveys C. elegans carbohydrate metabolism: evidence for an anaerobic shift in the long-lived dauer larva. Mech Aging Dev 124: 779-800.
16. Reich M, Ohm K, Angelo M, Tamayo P, Mesirov JP (2004) GeneCluster 2.0: an advanced toolset for bioarray analysis. Bioinformatics 20: 1797-1798.
17. Lee ML, Kuo FC, Whitmore GA, Sklar J (2000) Importance of replication in microarray gene expression studies: statistical methods and evidence from repetitive cDNA hybridizations. Proc Natl Acad Sci USA 97: 9834-9839.
18. Schaffitzel E, Hertweck M (2006) Recent aging research in Caenorhabditis elegans. Exp Gerontol 41: 557-563.
19. Vanfleteren JR, Braeckman BP (1999) Mechanisms of life span determination in Caenorhabditis elegans. Neurobiol Aging 20: 487-502.
20. Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366: 461-464.
21. Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
22. Paradis S, Ruvkun G (1998) Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. Genes Dev 12: 2488-2498.
23. Li W, Kennedy SG, Ruvkun G (2003) daf-28 encodes a C. elegans insulin suprefamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway. Genes Dev 17: 844-858.
24. Cao J, Li JL, Li D, Tobin JF, Gimeno RE (2006) Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis. Proc Natl Acad Sci USA 103: 19695-19700.
25. O'Riordan V, Burnell AM (1990) Intermediary metabolism in the dauer larva. II. The glyoxylate cycle and fatty acid oxidation. Comp Biochem Physiol 95B: 125-130.
26. Jones SJ, Riddle DL, Pouzyrev AT, Velculescu VE, Hillier L, et al. (2001) Changes in gene expression associated with developmental arrest and longevity in Caenorhabditis elegans. Genome Res 11: 1346-1352.
27. Larsen PL (1993) Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc Natl Acad Sci USA 90: 8905-8909.
28. Vanfleteren JR, De Vreese A (1996) Rate of aerobic metabolism and superoxide production rate potential in the nematode Caenorhabditis elegans. J Exp Zool 274: 93-100.
29. McGarry JD, Brown NF (1997) The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur J Biochem 244: 1-14.
30. Lund J, Tedesco P, Duke K, Wang J, Kim SK, et al. (2002) Transcriptional profile of aging in C. elegans. Curr Biol 12: 1566-1573.
31. McElwee J, Bubb K, Thomas JH (2003) Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2: 111-121.
32. Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, et al. (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277-283.
33. Oldham S, Hafen E (2003) Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol 13: 79-85.
34. Hay N, Sonenberg N (2004) Upstream and downstream of mTOR. Genes Dev 18: 1926-1945.
35. Long X, Spvcher C, Han ZS, Rose AM, Muller F, et al. (2002) TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. 12: 1448-14461.
36. Jia K, Chen D, Riddle DL (2004) The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131: 3897-906.
37. Vellai T, Takacs-Vellai K, Zhang Y, Kovacs AL, Orosz L, et al. (2003) Genetics: influence of TOR kinase on lifespan in C. elegans. Nature 426: 620.
38. Nehrke K (2003) A reduction in intestinal cell pHi due to loss of the Caenorhabditis elegans Na+/H+ exchanger NHX-2 increases life span. J Biol Chem 278: 44657-44666.
39. Meléndez A, Tallóczy Z, Seaman M, Eskelinen EL, Hall DH, et al. (2003) Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301: 1387-1391.
40. O'Riordan V, Burnell AM (1989) Intermediary metabolism in the dauer larva of the nematode C. elegans. I. Glycolysis, gludoneogenesis, oxidate phoshphorylation and the tricarboxylic acid cycle. Comp Biochem Physiol 92B: 233-238.
41. Tóth ML, Simon P, Kovács AL, Vellai T (2007) Influence of autophagy genes on ion-channel-dependent neuronal degradation in Caenorhabditis elegans. J Cell Sci 120: 1134-1141.
42. Hars ES, Qi H, Ryazanov AG, Jin S, Cai L, et al. (2007) Autophagy regulates ageing in C. elegans. Autophagy 3: 93-95.
43. Coleman RA, Lee DP (2004) Enzymes of triacylglycerol synthesis and their regulation. Prog Lipid Res 43: 134-176.
44. Wadsworth WG, Riddle DL (1989) Developmental regulation of energy metabolism in Caenorhabditis elegans. Dev Biol 132: 167-173.
45. Ruzanov P, Riddle DL, Marra MA, McKay SJ, Jones SM (2007) Genes that may modulate longevity in C. elegans in both dauer larvae and long-lived daf-2 adults. Exp Gerontol Aug;42: 825-39.
46. Dwinell LD (1997) The pinewood nematode: regulation and mitigation. Annu Rev Physiopathol 35: 135-166.
47. Mamiya Y (1983) Pathology of the pine wilt disease cuased by Bursaphelenchus xylophilus. Annu Rev Phytopathol 21: 201-220.
48. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29.
49. Van Gilst MR, Hadjivassiliou H, Yamamoto KR (2005) A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. PNAS 102: 13496-13501.
50. Ashrafi K, Chang EY, Watts JL, Fraser AG, Kamath RS, et al. (2003) Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421: 268-272.
51. Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-237.