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Volumn 41, Issue 1, 2008, Pages 120-129

Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CARRIER PROTEIN; CELL SURFACE RECEPTOR; FOLATE BINDING PROTEIN; FOLATE-BINDING PROTEIN; FOLIC ACID; UNCLASSIFIED DRUG;

EID: 38949215454     PISSN: 00014842     EISSN: None     Source Type: Journal    
DOI: 10.1021/ar7000815     Document Type: Article
Times cited : (1027)

References (61)
  • 1
    • 33947362046 scopus 로고    scopus 로고
    • The folate receptor: What does it promise in tissue-targeted therapeutics
    • Salazar, M. D.; Ratnam, M. The folate receptor: What does it promise in tissue-targeted therapeutics. Cancer Metastasis Rev 2007, 26, 141-152.
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 141-152
    • Salazar, M.D.1    Ratnam, M.2
  • 2
    • 1942535110 scopus 로고    scopus 로고
    • Folate receptor-targeted drugs for cancer and inflammatory diseases
    • Low, P. S.; Antony, A. C. Folate receptor-targeted drugs for cancer and inflammatory diseases. Adv. Drug Delivery Rev. 2004, 56, 1055-1231.
    • (2004) Adv. Drug Delivery Rev , vol.56 , pp. 1055-1231
    • Low, P.S.1    Antony, A.C.2
  • 3
    • 26844549171 scopus 로고    scopus 로고
    • Inhibition of glycinamide ribonucleotide formyltransferase results in selective inhibition of macrophage cytokine secretion in vitro and in vivo efficacy in rat adjuvant arthritis
    • Chintalacharuvu, S.; Evans, G. F.; Shih, C.; Bryant, H. U.; Sandusky, G. E.; Zuckerman, S. H. Inhibition of glycinamide ribonucleotide formyltransferase results in selective inhibition of macrophage cytokine secretion in vitro and in vivo efficacy in rat adjuvant arthritis. Clin. Exp. Rheumatol. 2005, 23, 438-446.
    • (2005) Clin. Exp. Rheumatol , vol.23 , pp. 438-446
    • Chintalacharuvu, S.1    Evans, G.F.2    Shih, C.3    Bryant, H.U.4    Sandusky, G.E.5    Zuckerman, S.H.6
  • 5
    • 1942439032 scopus 로고    scopus 로고
    • Antifolates targeted specifically to the folate receptor
    • Jackman, A. L.; Theti, D. S.; Gibbs, D. D. Antifolates targeted specifically to the folate receptor. Adv. Drug Delivery Rev. 2004, 56, 1111-1125.
    • (2004) Adv. Drug Delivery Rev , vol.56 , pp. 1111-1125
    • Jackman, A.L.1    Theti, D.S.2    Gibbs, D.D.3
  • 6
    • 0346258211 scopus 로고    scopus 로고
    • LY309887, antifolate via the folate receptor suppresses murine type II collagen-induced arthritis
    • Nagayoshi, R.; Nakamura, M.; Ijiri, K.; Yoshida, H.; Komiya, S.; Matsuyama, T. LY309887, antifolate via the folate receptor suppresses murine type II collagen-induced arthritis. Clin. Exp. Rheumatol. 2003, 21, 719-725.
    • (2003) Clin. Exp. Rheumatol , vol.21 , pp. 719-725
    • Nagayoshi, R.1    Nakamura, M.2    Ijiri, K.3    Yoshida, H.4    Komiya, S.5    Matsuyama, T.6
  • 7
    • 0037742256 scopus 로고    scopus 로고
    • Selective delivery of CB300638, a cyclopenta[(g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the α-isoform of the folate receptor
    • Theti, D. S.; Bavetsias, V.; Skelton, L. A.; Titley, J.; Gibbs, D.; Jansen, G.; Jackman, A. L. Selective delivery of CB300638, a cyclopenta[(g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the α-isoform of the folate receptor. Cancer Res. 2003, 63, 3612-3618.
    • (2003) Cancer Res , vol.63 , pp. 3612-3618
    • Theti, D.S.1    Bavetsias, V.2    Skelton, L.A.3    Titley, J.4    Gibbs, D.5    Jansen, G.6    Jackman, A.L.7
  • 8
    • 0000989463 scopus 로고
    • Receptor-mediated endocytosis in plant cells
    • Horn, M. A.; Heinstein, P. F.; Low, P. S. Receptor-mediated endocytosis in plant cells. Plant Cell 1989, 1, 1003-1009.
    • (1989) Plant Cell , vol.1 , pp. 1003-1009
    • Horn, M.A.1    Heinstein, P.F.2    Low, P.S.3
  • 9
    • 0001672151 scopus 로고
    • Characterization of parameters influencing receptor-mediated endocytosis in cultured soybean cells
    • Horn, M. A.; Heinstein, P. F.; Low, P. S. Characterization of parameters influencing receptor-mediated endocytosis in cultured soybean cells. Plant Physiol. 1992, 98, 673-679.
    • (1992) Plant Physiol , vol.98 , pp. 673-679
    • Horn, M.A.1    Heinstein, P.F.2    Low, P.S.3
  • 10
    • 0030472471 scopus 로고    scopus 로고
    • Riboflavin-enhanced transport of serum albumin across the distal pulmonary epithelium
    • Wangensteen, O. D.; Bartlett, M. M.; James, J. K.; Yang, Z. F.; Low, P. S. Riboflavin-enhanced transport of serum albumin across the distal pulmonary epithelium. Pharm. Res. 1996, 13, 1861-1864.
    • (1996) Pharm. Res , vol.13 , pp. 1861-1864
    • Wangensteen, O.D.1    Bartlett, M.M.2    James, J.K.3    Yang, Z.F.4    Low, P.S.5
  • 11
    • 0025951931 scopus 로고
    • Delivery of macromolecules into living cells: A method that exploits folate receptor endocytosis
    • Leamon, C. P.; Low, P. S. Delivery of macromolecules into living cells: A method that exploits folate receptor endocytosis. Proc. Natl. Acad. Sci. U.S.A. 1991, 88, 5572-5576.
    • (1991) Proc. Natl. Acad. Sci. U.S.A , vol.88 , pp. 5572-5576
    • Leamon, C.P.1    Low, P.S.2
  • 12
    • 0022358451 scopus 로고
    • Studies of the role of a particulate folate-binding protein in the uptake of 5-methyltetrahydrofolate by cultured human KB cells
    • Antony, A. C.; Kane, M. A.; Portillo, R. M.; Elwood, P. C.; Kolhouse, J. F. Studies of the role of a particulate folate-binding protein in the uptake of 5-methyltetrahydrofolate by cultured human KB cells. J. Biol Chem. 1985, 260, 14911-14917.
    • (1985) J. Biol Chem , vol.260 , pp. 14911-14917
    • Antony, A.C.1    Kane, M.A.2    Portillo, R.M.3    Elwood, P.C.4    Kolhouse, J.F.5
  • 13
    • 0344401038 scopus 로고
    • Receptor-mediated folate accumulation is regulated by the cellular folate content
    • Kamen, B. A.; Capdevila, A. Receptor-mediated folate accumulation is regulated by the cellular folate content. Proc. Natl. Acad. Sci. U.S.A. 1986, 83, 5983-5987.
    • (1986) Proc. Natl. Acad. Sci. U.S.A , vol.83 , pp. 5983-5987
    • Kamen, B.A.1    Capdevila, A.2
  • 14
    • 0027280460 scopus 로고
    • Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells
    • Leamon, C. P.; Low, P. S. Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells. Biochem. J. 1993, 291 (part 3), 855-860.
    • (1993) Biochem. J , vol.291 , Issue.PART 3 , pp. 855-860
    • Leamon, C.P.1    Low, P.S.2
  • 15
    • 0027436790 scopus 로고
    • Endocytosis of folate-protein conjugates: Ultrastructural localization in KB cells
    • Turek, J. J.; Leamon, C. P.; Low, P. S. Endocytosis of folate-protein conjugates: Ultrastructural localization in KB cells. J. Cell Sci. 1993, 106 (part 1), 423-430.
    • (1993) J. Cell Sci , vol.106 , Issue.PART 1 , pp. 423-430
    • Turek, J.J.1    Leamon, C.P.2    Low, P.S.3
  • 16
    • 0027423248 scopus 로고
    • Cytotoxicity of folate-Pseudomonas exotoxin conjugates toward tumor cells. Contribution of translocation domain
    • Leamon, C. P.; Pastan, I.; Low, P. S. Cytotoxicity of folate-Pseudomonas exotoxin conjugates toward tumor cells. Contribution of translocation domain. J. Biol. Chem. 1993, 268, 24847-24854.
    • (1993) J. Biol. Chem , vol.268 , pp. 24847-24854
    • Leamon, C.P.1    Pastan, I.2    Low, P.S.3
  • 17
    • 33748792549 scopus 로고    scopus 로고
    • Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging
    • Yang, J.; Chen, H.; Vlahov, I. R.; Cheng, J. X.; Low, P. S. Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 13872-13877.
    • (2006) Proc. Natl. Acad. Sci. U.S.A , vol.103 , pp. 13872-13877
    • Yang, J.1    Chen, H.2    Vlahov, I.R.3    Cheng, J.X.4    Low, P.S.5
  • 20
    • 0025949661 scopus 로고
    • Folate-binding protein is a marker for ovarian cancer
    • Campbell, I. G.; Jones, T. A.; Foulkes, W. D.; Trowsdale, J. Folate-binding protein is a marker for ovarian cancer. Cancer Res. 1991, 51, 5329-5338.
    • (1991) Cancer Res , vol.51 , pp. 5329-5338
    • Campbell, I.G.1    Jones, T.A.2    Foulkes, W.D.3    Trowsdale, J.4
  • 21
    • 0026496180 scopus 로고
    • Cytotoxicity of momordin-folate conjugates in cultured human cells
    • Leamon, C. P.; Low, P. S. Cytotoxicity of momordin-folate conjugates in cultured human cells. J. Biol. Chem. 1992, 267, 24966-24971.
    • (1992) J. Biol. Chem , vol.267 , pp. 24966-24971
    • Leamon, C.P.1    Low, P.S.2
  • 22
    • 0028001056 scopus 로고
    • Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis
    • Lee, R. J.; Low, P. S. Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis. J. Biol. Chem. 1994, 269, 3198-3204.
    • (1994) J. Biol. Chem , vol.269 , pp. 3198-3204
    • Lee, R.J.1    Low, P.S.2
  • 23
    • 0028794831 scopus 로고
    • Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro
    • Lee, R. J.; Low, P. S. Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro. Biochim. Biophys. Acta 1995, 1233, 134-144.
    • (1995) Biochim. Biophys. Acta , vol.1233 , pp. 134-144
    • Lee, R.J.1    Low, P.S.2
  • 24
    • 0033106119 scopus 로고    scopus 로고
    • Targeting folate receptor with folate linked to extremities of polyethylene glycol)-grafted liposomes: In vitro studies
    • Gabizon, A.; Horowitz, A. T.; Goren, D.; Tzemach, D.; Mandelbaum-Shavit, F.; Qazen, M. M.; Zalipsky, S. Targeting folate receptor with folate linked to extremities of polyethylene glycol)-grafted liposomes: In vitro studies. Bioconjugate Chem. 1999, 10, 289-298.
    • (1999) Bioconjugate Chem , vol.10 , pp. 289-298
    • Gabizon, A.1    Horowitz, A.T.2    Goren, D.3    Tzemach, D.4    Mandelbaum-Shavit, F.5    Qazen, M.M.6    Zalipsky, S.7
  • 25
    • 0037050752 scopus 로고    scopus 로고
    • Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs
    • Turk, M. J.; Reddy, J. A.; Chmielewski, J. A.; Low, P. S. Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs. Biochim. Biophys. Acta 2002, 1559, 56-68.
    • (2002) Biochim. Biophys. Acta , vol.1559 , pp. 56-68
    • Turk, M.J.1    Reddy, J.A.2    Chmielewski, J.A.3    Low, P.S.4
  • 26
    • 0031752755 scopus 로고    scopus 로고
    • The effects of pH and intraliposomal buffer strength on the rate of liposome content release and intracellular drug delivery
    • Lee, R. J.; Wang, S.; Turk, M. J.; Low, P. S. The effects of pH and intraliposomal buffer strength on the rate of liposome content release and intracellular drug delivery. Biosci. Rep. 1998, 18, 69-78.
    • (1998) Biosci. Rep , vol.18 , pp. 69-78
    • Lee, R.J.1    Wang, S.2    Turk, M.J.3    Low, P.S.4
  • 27
    • 0033971786 scopus 로고    scopus 로고
    • Enhanced folate receptor mediated gene therapy using a novel pH-sensitive lipid formulation
    • Reddy, J. A.; Low, P. S. Enhanced folate receptor mediated gene therapy using a novel pH-sensitive lipid formulation. J. Controlled Release 2000, 64, 27-37.
    • (2000) J. Controlled Release , vol.64 , pp. 27-37
    • Reddy, J.A.1    Low, P.S.2
  • 28
    • 0032508960 scopus 로고    scopus 로고
    • Diplasmenylcholine-folate liposomes: An efficient vehicle for intracellular drug delivery
    • Rui, Y.; Wang, S.; Low, P. S.; Thompson, D. H. Diplasmenylcholine-folate liposomes: An efficient vehicle for intracellular drug delivery. J. Am. Chem. Soc. 1998, 120, 11213-11218.
    • (1998) J. Am. Chem. Soc , vol.120 , pp. 11213-11218
    • Rui, Y.1    Wang, S.2    Low, P.S.3    Thompson, D.H.4
  • 29
    • 0028924955 scopus 로고
    • Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol
    • Wang, S.; Lee, R. J.; Cauchon, G.; Gorenstein, D. G.; Low, P. S. Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 3318-3322.
    • (1995) Proc. Natl. Acad. Sci. U.S.A , vol.92 , pp. 3318-3322
    • Wang, S.1    Lee, R.J.2    Cauchon, G.3    Gorenstein, D.G.4    Low, P.S.5
  • 30
    • 0032726144 scopus 로고    scopus 로고
    • Optimization of folate-conjugated liposomal vectors for folate receptor-mediated gene therapy
    • Reddy, J. A.; Dean, D.; Kennedy, M. D.; Low, P. S. Optimization of folate-conjugated liposomal vectors for folate receptor-mediated gene therapy. J. Pharm. Sci. 1999, 88, 1112-1118.
    • (1999) J. Pharm. Sci , vol.88 , pp. 1112-1118
    • Reddy, J.A.1    Dean, D.2    Kennedy, M.D.3    Low, P.S.4
  • 33
    • 0033625094 scopus 로고    scopus 로고
    • 99mTc]DTPA-folate and its evaluation as a folate-receptor-targeted radiopharmaceutical
    • 99mTc]DTPA-folate and its evaluation as a folate-receptor-targeted radiopharmaceutical. Bioconjugate Chem. 2000, 11, 253-257.
    • (2000) Bioconjugate Chem , vol.11 , pp. 253-257
    • Mathias, C.J.1    Hubers, D.2    Low, P.S.3    Green, M.A.4
  • 35
    • 0031658693 scopus 로고    scopus 로고
    • Indium-111-DTPA-folate as a potential folate-receptor-targeted radiopharmaceutical
    • Mathias, C. J.; Wang, S.; Waters, D. J.; Turek, J. J.; Low, P. S.; Green, M. A. Indium-111-DTPA-folate as a potential folate-receptor-targeted radiopharmaceutical. J. Nucl. Med. 1998, 39, 1579-1585.
    • (1998) J. Nucl. Med , vol.39 , pp. 1579-1585
    • Mathias, C.J.1    Wang, S.2    Waters, D.J.3    Turek, J.J.4    Low, P.S.5    Green, M.A.6
  • 36
    • 0030611096 scopus 로고    scopus 로고
    • 111In]DTPA- folate for use as a tumor-targeted radiopharmaceutical. Bioconjugate Chem. 1997, 8, 673-679.
    • 111In]DTPA- folate for use as a tumor-targeted radiopharmaceutical. Bioconjugate Chem. 1997, 8, 673-679.
  • 37
    • 0036068396 scopus 로고    scopus 로고
    • Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis
    • Turk, M. J.; Breur, G. J.; Widmer, W. R.; Paulos, C. M.; Xu, L. C.; Grote, L. A.; Low, P. S. Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis. Arthritis Rheum. 2002, 46, 1947-1955.
    • (2002) Arthritis Rheum , vol.46 , pp. 1947-1955
    • Turk, M.J.1    Breur, G.J.2    Widmer, W.R.3    Paulos, C.M.4    Xu, L.C.5    Grote, L.A.6    Low, P.S.7
  • 39
    • 0036242840 scopus 로고    scopus 로고
    • Synthesis and evaluation of taxol-folic acid conjugates as targeted antineoplastics
    • Lee, J. W.; Lu, J. Y.; Low, P. S.; Fuchs, P. L. Synthesis and evaluation of taxol-folic acid conjugates as targeted antineoplastics. Bioorg. Med. Chem. 2002, 10, 2397-2414.
    • (2002) Bioorg. Med. Chem , vol.10 , pp. 2397-2414
    • Lee, J.W.1    Lu, J.Y.2    Low, P.S.3    Fuchs, P.L.4
  • 42
    • 33749034747 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of EC140: A novel folate-targeted vinca alkaloid conjugate
    • Leamon, C. P.; Reddy, J. A.; Vlahov, I. R.; Kleindl, P. J.; Vetzel, M.; Westrick, E. Synthesis and biological evaluation of EC140: A novel folate-targeted vinca alkaloid conjugate. Bioconjugate Chem. 2006, 17, 1226-1232.
    • (2006) Bioconjugate Chem , vol.17 , pp. 1226-1232
    • Leamon, C.P.1    Reddy, J.A.2    Vlahov, I.R.3    Kleindl, P.J.4    Vetzel, M.5    Westrick, E.6
  • 43
    • 33747349484 scopus 로고    scopus 로고
    • Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide
    • Vlahov, I. R.; Santhapuram, H. K.; Kleindl, P. J.; Howard, S. J.; Stanford, K. M.; Leamon, C. P. Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide. Bioorg. Med. Chem. Lett. 2006, 16, 5093-5096.
    • (2006) Bioorg. Med. Chem. Lett , vol.16 , pp. 5093-5096
    • Vlahov, I.R.1    Santhapuram, H.K.2    Kleindl, P.J.3    Howard, S.J.4    Stanford, K.M.5    Leamon, C.P.6
  • 45
    • 0030600223 scopus 로고    scopus 로고
    • Measurement of endosome pH following folate receptor-mediated endocytosis
    • Lee, R. J.; Wang, S.; Low, P. S. Measurement of endosome pH following folate receptor-mediated endocytosis. Biochim. Biophys. Acta 1996, 1312, 237-242.
    • (1996) Biochim. Biophys. Acta , vol.1312 , pp. 237-242
    • Lee, R.J.1    Wang, S.2    Low, P.S.3
  • 46
    • 34247249415 scopus 로고    scopus 로고
    • Characterization of the pH of folate receptor-containing endosomes and the rate of hydrolysis of internalized acid-labile folate-drug conjugates
    • Yang, J.; Chen, H.; Vlahov, I. R.; Cheng, J. X.; Low, P. S. Characterization of the pH of folate receptor-containing endosomes and the rate of hydrolysis of internalized acid-labile folate-drug conjugates. J. Pharmacol. Exp. Ther. 2007, 321, 462-468.
    • (2007) J. Pharmacol. Exp. Ther , vol.321 , pp. 462-468
    • Yang, J.1    Chen, H.2    Vlahov, I.R.3    Cheng, J.X.4    Low, P.S.5
  • 47
    • 9444279605 scopus 로고    scopus 로고
    • Ligand binding and kinetics of folate receptor recycling in vivo: Impact on receptor-mediated drug delivery
    • Paulos, C. M.; Reddy, J. A.; Leamon, C. P.; Turk, M. J.; Low, P. S. Ligand binding and kinetics of folate receptor recycling in vivo: Impact on receptor-mediated drug delivery. Mol. Pharmacol. 2004, 66, 1406-1414.
    • (2004) Mol. Pharmacol , vol.66 , pp. 1406-1414
    • Paulos, C.M.1    Reddy, J.A.2    Leamon, C.P.3    Turk, M.J.4    Low, P.S.5
  • 48
    • 0036219732 scopus 로고    scopus 로고
    • Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors
    • Lu, Y.; Low, P. S. Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors. Cancer Immunol. Immunother. 2002, 51, 153-162.
    • (2002) Cancer Immunol. Immunother , vol.51 , pp. 153-162
    • Lu, Y.1    Low, P.S.2
  • 49
    • 0348223342 scopus 로고    scopus 로고
    • Optical imaging of metastatic tumors using a folate-targeted fluorescent probe
    • Kennedy, M. D.; Jallad, K. N.; Thompson, D. H.; Ben-Amotz, D.; Low, P. S. Optical imaging of metastatic tumors using a folate-targeted fluorescent probe. J. Biomed. Opt. 2003, 8, 636-641.
    • (2003) J. Biomed. Opt , vol.8 , pp. 636-641
    • Kennedy, M.D.1    Jallad, K.N.2    Thompson, D.H.3    Ben-Amotz, D.4    Low, P.S.5
  • 50
    • 4344586166 scopus 로고    scopus 로고
    • Folate-conjugated liposomes preferentially target macrophages associated with ovarian carcinoma
    • Turk, M. J.; Waters, D. J.; Low, P. S. Folate-conjugated liposomes preferentially target macrophages associated with ovarian carcinoma. Cancer Lett. 2004, 213, 165-172.
    • (2004) Cancer Lett , vol.213 , pp. 165-172
    • Turk, M.J.1    Waters, D.J.2    Low, P.S.3
  • 51
    • 1942503257 scopus 로고    scopus 로고
    • Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis
    • Paulos, C. M.; Turk, M. J.; Breur, G. J.; Low, P. S. Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis. Adv. Drug Delivery Rev. 2004, 56, 1205-1217.
    • (2004) Adv. Drug Delivery Rev , vol.56 , pp. 1205-1217
    • Paulos, C.M.1    Turk, M.J.2    Breur, G.J.3    Low, P.S.4
  • 52
    • 0033509413 scopus 로고    scopus 로고
    • Selective expression of folate receptor β and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis
    • Nakashima-Matsushita, N.; Homma, T.; Yu, S.; Matsuda, T.; Sunahara, N.; Nakamura, T.; Tsukano, M.; Ratnam, M.; Matsuyama, T. Selective expression of folate receptor β and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis. Arthritis Rheum. 1999, 42, 1609-1616.
    • (1999) Arthritis Rheum , vol.42 , pp. 1609-1616
    • Nakashima-Matsushita, N.1    Homma, T.2    Yu, S.3    Matsuda, T.4    Sunahara, N.5    Nakamura, T.6    Tsukano, M.7    Ratnam, M.8    Matsuyama, T.9
  • 53
    • 34547109974 scopus 로고    scopus 로고
    • Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis
    • Paulos, C. M.; Varghese, B.; Widmer, W. R.; Breur, G. J.; Vlashi, E.; Low, P. S. Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis. Arthritis Res. Ther. 2006, 8, R77.
    • (2006) Arthritis Res. Ther , vol.8
    • Paulos, C.M.1    Varghese, B.2    Widmer, W.R.3    Breur, G.J.4    Vlashi, E.5    Low, P.S.6
  • 55
    • 0035232487 scopus 로고    scopus 로고
    • Cooperation of liver cells in health and disease
    • Kmiec, Z. Cooperation of liver cells in health and disease. Adv. Anat. Embryol. Cell Biol. 2001, 161 (3-13), 1-151.
    • (2001) Adv. Anat. Embryol. Cell Biol , vol.161 , Issue.3-13 , pp. 1-151
    • Kmiec, Z.1
  • 56
    • 0034785930 scopus 로고    scopus 로고
    • Tumour necrosis factor-α blockers in rheumatoid arthritis: Review of the clinical experience
    • Richard-Miceli, C.; Dougados, M. Tumour necrosis factor-α blockers in rheumatoid arthritis: Review of the clinical experience. BioDrugs 2001, 15, 251-259.
    • (2001) BioDrugs , vol.15 , pp. 251-259
    • Richard-Miceli, C.1    Dougados, M.2
  • 57
    • 0033765449 scopus 로고    scopus 로고
    • Role of interleukin 1 and interleukin 1 receptor antagonist in the mediation of rheumatoid arthritis
    • Schiff, M. H. Role of interleukin 1 and interleukin 1 receptor antagonist in the mediation of rheumatoid arthritis. Ann. Rheum. Dis. 2000, 59 (supplement 1), i103-i108.
    • (2000) Ann. Rheum. Dis , vol.59 , Issue.SUPPL.EMENT 1
    • Schiff, M.H.1
  • 58
    • 0032818121 scopus 로고    scopus 로고
    • Celecoxib, a selective cyclooxygenase-2 inhibitor for the treatment of rheumatoid arthritis and osteoarthritis
    • and discussion 1427-1428
    • Goldenberg, M. M. Celecoxib, a selective cyclooxygenase-2 inhibitor for the treatment of rheumatoid arthritis and osteoarthritis. Clin. Ther. 1999, 21, 1497-1513, and discussion 1427-1428.
    • (1999) Clin. Ther , vol.21 , pp. 1497-1513
    • Goldenberg, M.M.1
  • 59
    • 2942672189 scopus 로고    scopus 로고
    • A review of the use of infliximab to manage cutaneous dermatoses
    • Gupta, A. K.; Skinner, A. R. A review of the use of infliximab to manage cutaneous dermatoses. J. Cutan. Med. Surg. 2004, 8, 77-89.
    • (2004) J. Cutan. Med. Surg , vol.8 , pp. 77-89
    • Gupta, A.K.1    Skinner, A.R.2
  • 60
    • 3242726883 scopus 로고    scopus 로고
    • Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy
    • Sandoval, R. M.; Kennedy, M. D.; Low, P. S.; Molitoris, B. A. Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy. Am. J. Physiol. Cell Physiol. 2004, 287, C517-C526.
    • (2004) Am. J. Physiol. Cell Physiol , vol.287
    • Sandoval, R.M.1    Kennedy, M.D.2    Low, P.S.3    Molitoris, B.A.4


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