Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein

Pharmaceutical Research

Volumn 17, Issue 7, 2000, Pages 803-810

  Brimer, Cynthia ^a   Dalton, James T ^b   Zhu, Zixin ^b   Schuetz, John ^a,b   Yasuda, Kazuto ^a   Vanin, Elio ^a   Relling, Mary V ^a,b   Lu, Yi ^c   Schuetz, Erin G ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

Caco 2; CYP3A4; LLC PK1; Pgp

Indexed keywords

CYTOCHROME P450 3A4; DIGOXIN; GLYCOPROTEIN P; MIDAZOLAM; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; TESTOSTERONE; VINBLASTINE;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL CULTURE; CELL LINE; CELL MEMBRANE; CELL METABOLISM; CELL POLARITY; CONTROLLED STUDY; DRUG TRANSPORT; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CACO-2 CELLS; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; LLC-PK1 CELLS; MIXED FUNCTION OXYGENASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; P-GLYCOPROTEIN; SWINE; TRANSFECTION;

EID: 0033849236     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007599923694     Document Type: Article

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