1,25-Dihydroxyvitamin D and 25-hydroxyvitamin D - Mediated regulation of TRPV6 (a putative epithelial calcium channel) mRNA expression in Caco-2 cells

European Journal of Nutrition

Volumn 45, Issue 4, 2006, Pages 196-204

  Taparia, Shveta ^a,b   Fleet, James C ^c   Peng, Ji Bin ^d   Xiang, Dong Wang ^a   Wood, Richard J ^a  

^a TUFTS UNIVERSITY   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c PURDUE UNIVERSITY   (United States)

^d University of Alabama at Birmingham   (United States)

Author keywords

CaT1; Gene expression; Intestine; TRPV6; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; CALCIUM CHANNEL; CYCLOHEXIMIDE; CYTOCHROME P450; CYTOCHROME P450 27B1; DACTINOMYCIN; INSULIN; MESSENGER RNA; OXYGENASE; SELENIUM; TRANSFERRIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR; VANILLOID RECEPTOR 6; VITAMIN D;

ARTICLE; AUTOCRINE EFFECT; CELL CULTURE; CELL LINE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLING; SIGNAL TRANSDUCTION;

CACO-2 CELLS; CALCIUM CHANNELS; CYCLOHEXIMIDE; DACTINOMYCIN; HUMANS; PROTEIN SYNTHESIS INHIBITORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRPV CATION CHANNELS; VITAMIN D;

EID: 33646892848     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-005-0586-3     Document Type: Article

References (37)

1. Norman AW (1990) Intestinal calcium absorption: a vitamin D-hormone-mediated adaptive response. Am J Clin Nutr 51:290-300
2. Bronner F (1991) Calcium transport across epithelia. Int Rev Cytol 131:169-212
3. Clapham DE (2003) TRP channels as cellular sensors. Nature 426:517-524
4. Peng JB, Chen XZ, Berger UV, Vassilev PM, Tsukaguchi H, Brown EM, Hediger MA (1999) Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption. J Biol Chem 274:22739-22746
5. Peng JB, Chen XZ, Berger UV, Weremowicz S, Morton CC, Vassilev PM, Brown EM, Hediger MA (2000) Human calcium transport protein CaT1. Biochem Biophys Res Commun 278:326-332
6. Wood RJ, Tchack L, Taparia S (2001) 1,25-Dihydroxyvitamin D3 increases the expression of the CaT1 epithelial calcium channel in the Caco-2 human intestinal cell line. BMC Physiol 1:11
7. Giuliano AR, Wood RJ (1991) Vitamin D-regulated calcium transport in Caco-2 cells: unique in vitro model. Am J Physiol 260:G207-G212
8. Fleet JC, Wood RJ (1999) Specific 1,25(OH)2D3-mediated regulation of transcellular calcium transport in Caco-2 cells. Am J Physiol 276:G958-G964
9. Song Y, Peng X, Porta A, Takanaga H, Peng JB, Hediger MA, Fleet JC, Christakos S (2003) Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1,25 dihydroxyvitamin D3 in the intestine and kidney of mice. Endocrinology 144:3885-3894
10. Van Cromphaut SJ, Dewerchin M, Hoenderop JG, Stockmans I, Van Herck E, Kato S, Bindels RJ, Collen D, Carmeliet P, Bouillon R, Carmeliet G (2001) Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects. Proc Natl Acad Sci USA 98:13324-13329
11. Jones G, Strugnell SA, DeLuca HF (1998) Current understanding of the molecular actions of vitamin D Physiol Rev 78:1193-1231
12. Gonzalez EA, Disthabanchong S, Kowalewski R, Martin KJ (2002) Mechanisms of the regulation of EGF receptor gene expression by calcitriol and parathyroid hormone in UMR 106-01 cells. Kidney Int 61:1627-1634
13. 3 upregulates natriuretic peptide receptor-C expression in mouse osteoblasts. Am J Physiol 275:E965-E973
14. Mosavin R, Mellon WS (1996) Posttranscriptional regulation of osteocalcin mRNA in clonal osteoblast cells by 1,25-dihydroxyvitamin D3. Arch Biochem Biophys 332:142-152
15. Grumbles RM, Shao L, Jeffrey JJ, Howell DS (1996) Regulation of rat interstitial collagenase gene expression in growth cartilage and chondrocytes by vitamin D3, interleukin-1 beta, and okadaic acid. J Cell Biochem 63:395-409
16. Biskobing DM, Fan D, Rubin J (1997) c-fms mRNA is regulated posttranscriptionally by 1,25(OH)2D3 in HL-60 cells. Calcif Tissue Int 61:205-209
17. Tobler A, Miller CW, Norman AW, Koeffler HP (1988) 1,25-Dihydroxyvitamin D3 modulates the expression of a lymphokine (granulocyte-macrophage colony-stimulating factor) posttranscriptionally. J Clin Invest 81:1819-1823
18. Mangasarian K, Mellon WS (1993) 1,25-Dihydroxyvitamin D-3 destabilizes c-myc mRNA in HL-60 leukemic cells. Biochim Biophys Acta 1172:55-63
19. Lou YR, Laaksi I, Syvala H, Blauer M, Tammela TL, Ylikomi T, Tuohimaa P (2004) 25-hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells. Faseb J 18:332-334
20. Kallay E, Bareis P, Bajna E, Kriwanek S, Bonner E, Toyokuni S, Cross HS (2002) Vitamin D receptor activity and prevention of colonic hyperproliferation and oxidative stress. Food Chem Toxicol 40:1191-1196
21. Schwartz GG, Eads D, Rao A, Cramer SD, Willingham MC, Chen TC, Jamieson DP, Wang L, Burnstein KL, Holick, MF, Koumenis C (2004) Pancreatic cancer cells express 25-Hydroxyvitamin D-1-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3. Carcinogenesis 25:1015-1026
22. Zehnder D, Evans KN, Kilby MD, Bulmer JN, Innes BA, Stewart PM, Hewison M (2002) The ontogeny of 25-hydroxyvitamin D(3) 1alpha-hydroxylase expression in human placenta and decidua. Am J Pathol 161:105-114
23. Segersten U, Correa P, Hewison M, Hellman P, Dralle H, Carling T, Akerstrom G, Westin G (2002) 25-hydroxyvitamin D(3)-1alpha-hydroxylase expression in normal and pathological parathyroid glands. J Clin Endocrinol Metab 87:2967-2972
24. Friedrich M, Villena-Heinsen C, Axt-Fliedner R, Meyberg R, Tilgen W, Schmidt W, Reichrath J (2002) Analysis of 25-hydroxyvitamin D3-1alpha- hydroxylase in cervical tissue. Anticancer Res 22:183-186
25. Giuliano AR, Franceschi RT, Wood RJ (1991) Characterization of the vitamin D receptor from the Caco-2 human colon carcinoma cell line: effect of cellular differentiation. Arch Biochem Biophys 285:261-269
26. Shao A, Wood RJ, Fleet JC (2001) Increased vitamin D receptor level enhances 1,25-dihydroxyvitamin D3-mediated gene expression and calcium transport in Caco-2 cells. J Bone Miner Res 16:615-624
27. Bareis P, Kallay E, Bischof MG, Bises G, Hofer H, Potzi C, Manhardt T, Bland R, Cross HS (2002) Clonal differences in expression of 25-hydroxyvitamin D (3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3). Exp Cell Res 276:320-327
28. Cross HS, Peterlik M, Reddy GS, Schuster I (1997) Vitamin D metabolism in human colon adenocarcinoma-derived Caco-2 cells: expression of 25-hydroxyvitamin D3-1alpha-hydroxylase activity and regulation of side-chain metabolism. J Steroid Biochem Mol Biol 62:21-28
29. Fleet JC, Eksir F, Hance KW, Wood RJ (2002) Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines. Am J Physiol Gastrointest Liver Physiol 283:G618-G625
30. Peng JB, Brown EM, Hediger MA (2001) Structural conservation of the genes encoding CaT1, CaT2, and related cation channels. Genomics 76:99-109
31. Wang TT, Tavera-Mendoza LE, Laperriere D, Libby E, Macleod NB, Nagai Y, Bourdeau V, Konstorum A, Lallement B, Zhang R, Mader S, White JH (2005) Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol (Epub ahead of print)
32. Heaney RP, Barger-Lux MJ, Dowell MS, Chen TC, Holick MF (1997) Calcium absorptive effects of vitamin D and its major metabolites. J Clin Endocrinol Metab 82:4111-4116
33. Kratz A, Ferraro M, Sluss PM, Lewandrowski KB (2004) Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Laboratory reference values. N Engl J Med 351(15):1548-1563
34. Holick MF (2004) Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr 79:362-371
35. Lamprecht SA, Lipkin M (2004) Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms. Nat Rev Cancer 3:601-614
36. Cross HS, Kallay E, Farhan H, Weiland T, Manhardt T (2003) Regulation of extrarenal vitamin D metabolism as a tool for colon and prostate cancer prevention. Recent Results Cancer Res 164:413-425
37. Keenan MJ, Holmes RP (1991) The up-take and metabolism of 25-hydroxyvitamin D3 and vitamin D binding protein by cultured porcine kidney cells (LLC-PK1). Int J Biochem 23:1225-1230