Carrier mechanisms involved in the transepithelial transport of bis(POM)-PMEA and its metabolites across Caco-2 monolayers

Pharmaceutical Research

Volumn 15, Issue 8, 1998, Pages 1168-1173

  Annaert, P ^a   Van Gelder, J ^a   Naesens, L ^b   De Clercq, E ^b   Van Den Mooter, G ^a   Kinget, R ^a   Augustijns, P ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Antiviral; Bis(POM) PMEA; Caco 2; Carrier mechanisms; Drug efflux; Drug transport; Multi drug resistance; P glycoprotein

Indexed keywords

ADEFOVIR DIPIVOXIL; INDOMETACIN; PRODRUG; VERAPAMIL;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PENETRATION; DRUG TRANSPORT; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS;

ADENINE; ANTIVIRAL AGENTS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; EPITHELIUM; HUMANS; INDOMETHACIN; P-GLYCOPROTEIN; VERAPAMIL;

EID: 0031666188     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011923420719     Document Type: Article

References (21)

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